Patents by Inventor Frank Hecht

Frank Hecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7593581
    Abstract: Process for the acquisition of images from a sample with a microscope, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: September 22, 2009
    Assignee: Carl Zeiss Micro Imaging GmbH
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Patent number: 7456026
    Abstract: An arrangement for the detection of fluorescent light with at least one imaging microscope unit and at least one device component for analyzing molecular interactions in small volumes, wherein measurement locations for the analysis of molecular interaction are determined and selected in at least two dimensions by the imaging method; the imaging microscope unit and the device components are operated with a shared control unit; and at least the analysis results of the device component are graphically depicted via the control unit and a computer.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: November 25, 2008
    Assignee: Carl Zeiss MicroImaging GmbH
    Inventors: Reinhard Janka, Volker Juengel, Tilo Jankowski, Frank Hecht
  • Publication number: 20080149818
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with line by line scanning, whereas a scanning of the specimen for the creation of a specimen image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the specimen occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the specimen is carried out.
    Type: Application
    Filed: November 28, 2007
    Publication date: June 26, 2008
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20080068709
    Abstract: Method for actuation control of a microscope, in particular of a Laser Scanning Microscope, in which, at least one first illumination light, preferably moving at least in one direction, as well as at least one second illumination light moving at least in one direction, illuminate a sample through a beam combination, a detection of the light coming from the sample takes place, whereby, at least one part of the illumination light is generated through the splitting of the light from a common illuminating unit, characterized in that, by means of a common control unit, a controlled splitting into the first and the second illumination light takes place, in which the intensity of the first illuminating light, specified by the user or specified automatically, is assigned a higher priority (is prioritized) compared to the specified value for the second illumination light, and an adjustment for the second illumination light takes place until a maximum value is obtained, which is determined by the value specified for th
    Type: Application
    Filed: April 6, 2007
    Publication date: March 20, 2008
    Inventors: Bernhard Zimmermann, Ralf Netz, Frank Hecht, Joerg-Michael Funk, Ralf Engelmann
  • Publication number: 20080048105
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: March 12, 2007
    Publication date: February 28, 2008
    Applicant: CARL ZEISS JENA GMBH
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Patent number: 7323679
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with line by line scanning, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: January 29, 2008
    Assignee: Carl Zeiss Jena GmbH
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Patent number: 7235777
    Abstract: Light scanning microscope with an at least single-dimensional light distribution for grid-shaped illumination of a sample in a locally limited grid field and detector means for recording sample light as well as a sample table that moves in at least one direction, whereby in a first process step an illumination of the sample, detection of sample light and data recording of the detection is carried out during a movement of the sample table in at least a first direction over the dimensions of the grid field and the recording of the respective table position is assigned to the data recording.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: June 26, 2007
    Assignee: Carl Zeiss Jena GmbH
    Inventor: Frank Hecht
  • Publication number: 20070053594
    Abstract: Process for the acquisition of images from a probe with a light scanning electron microscope, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Application
    Filed: October 19, 2004
    Publication date: March 8, 2007
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Publication number: 20060273261
    Abstract: A Laser Scanning Microscope with an illumination radiation distribution, which is guided over a sample for scanning and in which an image of the sample is taken from the sample radiation generated and detected during the scanning, wherein the sample is sampled with an imaging rate of x images per second, wherein in a mode for the adjustment of the device parameters, the imaging rate is reduced with uniform sampling speed. preferably for sparing the sample the exposure, to a fraction X/Y of X, Y>1.
    Type: Application
    Filed: May 3, 2006
    Publication date: December 7, 2006
    Inventors: Ralf Wolleschensky, Wolfgang Bathe, Frank Hecht, Ralf Engelmann, Joerg Steinert
  • Publication number: 20060208178
    Abstract: Light scanning microscope with an at least single-dimensional light distribution for grid-shaped illumination of a sample in a locally limited grid field and detector means for recording sample light as well as a sample table that moves in at least one direction, whereby in a first process step an illumination of the sample, detection of sample light and data recording of the detection is carried out during a movement of the sample table in at least a first direction over the dimensions of the grid field and the recording of the respective table position is assigned to the data recording.
    Type: Application
    Filed: March 1, 2006
    Publication date: September 21, 2006
    Inventor: Frank Hecht
  • Publication number: 20060013492
    Abstract: Process for the acquisition of images from a probe with a light scanning electron microscope with punctiform light source distribution, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Publication number: 20060011861
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20060011812
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with punctual light source distribution, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20060011859
    Abstract: Procedure for the image acquisition of objects by means of a light raster microscope with line by line scanning, whereas a scanning of the probe for the creation of a probe image occurs in scanning steps and the distance between at least two scanning steps is variably adjustable and at least a second scanning of the probe occurs, during which the position of the scanning steps is shifted with regard to the scanning direction, whereas preferably a line by line scanning of the probe is carried out.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Ralf Wolleschensky, Frank Hecht, Ralf Engelmann
  • Publication number: 20060011860
    Abstract: Process for the acquisition of images from a probe with a microscope, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Publication number: 20060011822
    Abstract: Light scanning microscope with an at least single-dimensional light distribution for grid-shaped illumination of a sample in a locally limited grid field and detector means for recording sample light as well as a sample table that moves in at least one direction, whereby in a first process step an illumination of the sample, detection of sample light and data recording of the detection is carried out during a movement of the sample table in at least a first direction over the dimensions of the grid field and the recording of the respective table position is assigned to the data recording.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventor: Frank Hecht
  • Publication number: 20060013491
    Abstract: Process for the acquisition of images from a probe with a light scanning electron microscope with linear scanning, wherein detected image data that correspond to three dimensional probe regions are detected and stored to memory, wherein data compression ensues in that the data of images lying next to one another and over one another on the probe are taken into consideration during compression. A stack of images is advantageously recorded and images that are respectively adjacent in the image stack are consulted for the compression of data. Temporally and/or spectrally detected and stored data shall be consulted for the compression of data.
    Type: Application
    Filed: October 19, 2004
    Publication date: January 19, 2006
    Inventors: Frank Hecht, Ralf Engelmann, Ralf Wolleschensky
  • Publication number: 20050271549
    Abstract: An arrangement for the detection of fluorescent light with at least one imaging microscope unit and at least one device component for analyzing molecular interactions in small volumes, wherein in that measurement locations for the analysis of molecular interaction are determined and selected in at least two dimensions by the imaging method; the imaging microscope unit and the device components are operated with a shared control unit; and at least the analysis results of the device component are graphically depicted via the control unit and a computer.
    Type: Application
    Filed: February 15, 2001
    Publication date: December 8, 2005
    Inventors: Reinhard Janka, Volker Juengel, Tilo Jankowski, Frank Hecht
  • Patent number: 6819415
    Abstract: A method and arrangement are disclosed for increasing the depth contrast in microscope imaging. The method and implementation described can be designated as structured illumination for generating quasi-confocal optical sections. In implementing the method, a grating structure located in the field diaphragm plane of a microscope, the object plane and the TV intermediate image plane of a microscope are arranged confocally. The term “confocally” refers to the fact that the grating, object and the intermediate image plane are positioned on optically conjugate planes. By this arrangement, the grating structure is projected in the object plane of the microscope and the object which is structured in this way is imaged in the TV intermediate image plane of the microscope by the optical system following it. Optical sections are generated by calculating the modulation depth of the structured object.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: November 16, 2004
    Assignee: Carl Zeiss Jena GmbH
    Inventors: Volker Gerstner, Frank Hecht, Ralph Lange, Helmut Bloos
  • Publication number: 20030086067
    Abstract: The invention relates to a method for increasing the depth of contrast during microscopic imaging. The method and implementation described can be designated as structured illumination, which creates quasi-confocal optical sections. During the implementation of the method, a grid structure, located in the illumination field stop plane of a microscope, the object plane and the TV intermediate-image plane of a microscope are arranged “confocally”. This assembly enables the grid structure to be projected into the object plane of the microscope and the object, thus structured, to be reproduced on the TV intermediate-image plane using the following optical system. Optical sections are created by the calculation of the modulation depth of the structured object. The object is reproduced perpendicular to the direction of observation on several focus planes, to achieve a 3-dimensional registration of said object and is detected using an array-detector (e.g. CCD camera).
    Type: Application
    Filed: August 12, 2002
    Publication date: May 8, 2003
    Inventors: Volker Gerstner, Frank Hecht, Ralph Lange, Helmut Bloos