Abstract: The invention relates generally to the field of cancer diagnosis, prognosis, treatment and prevention. More particularly, the present invention relates to methods of diagnosing, treating and preventing lung cancer. In particular, aspects of the invention are directed to methods of diagnosing, treating and preventing small cell lung cancers. Methods of using a nucleic acid and/or a protein, which are differentially expressed in tumor cells, and antibodies immunospecific for the protein, to treat, diagnose and/or prevent said cancers, are provided for by the present invention.

Abstract: The disclosed technology relates to a single terminal (10, 110) with a terminal body (20, 120) designed in the shape of a frame and made of an electrically conductive material, with at least one connection pin (27, 127) being arranged on one exterior side (20, 120) and a clamping spring (30, 130) being inserted in the terminal body (20, 120).

Abstract: An oxidation catalyst is described for the exhaust gas purification of utility vehicles with diesel engines, which contains a substrate and a catalytically active coating of platinum, active aluminium oxide and aluminium-silicon mixed oxide. The two oxidic support materials, aluminium oxide and aluminium-silicon mixed oxide, are catalytically activated with platinum, the majority of platinum being present on the active aluminium oxide. The oxidation catalyst is distinguished by good NO oxidation rates together with a high poisoning resistance against sulfur compounds.

Abstract: Disclosed herein are formulations and methods of manufacture of compounds of formula (E): wherein X and Y independently represent leaving groups and A+ is an ammonium cation.

Abstract: The invention proposes a particulate filter having a catalytic coating which contains two catalysts arranged one behind the other. The first catalyst is located in the gas inlet region of the filter and contains a palladium/platinum catalyst. The second catalyst is arranged downstream of the first catalyst and preferably contains platinum alone as catalytically active component. The combination of these two catalysts provides the coated filter with a good ageing stability and resistance to sulphur poisoning.

Abstract: The invention relates to a radiation-curable printing medium based on a thermoplastic polymer and at least one radiation-curable monomeric compound. By means of a compound which comprises a heterocyclic ring, it is possible to achieve a favorable combination of properties comprising reactivity and flexibility of the decoration. Preferred monomeric compounds contain a 1,3-dioxolane or 1,3- or 1,4-dioxane ring, and an acrylic or methacrylic group is attached in the manner of an ester around a methylol group. The invention also provides transfers containing the printing medium and decorative preparations.

Abstract: A method for operating an internal combustion engine having several cylinders, successive time windows, each of which is assigned to a cylinder being defined in a control unit in one time window, a calculation of an ignition time, a start of a charging process for an ignition device, and a triggering of an ignition for a cylinder assigned to the time window being performed; it being necessary for an ignition to start the charging process for the ignition device, the extent of which is at least as long as one time period needed for charging; the following steps being carried out in each time window: ascertaining information for an ignition time for a cylinder assigned to the subsequent time window; establishing whether the ignition time for the cylinder assigned to the subsequent time window is after the beginning of the subsequent time window by at least the time needed for charging; if it is established that the ignition time for the cylinder assigned to the subsequent time window is after the beginning of t

Abstract: A method of assessing kidney function in a human subject to aid in the diagnosis of renal tubule diseases or conditions specific to a particular renal tubule region, comprises contacting a urine sample from said subject with a panel of capture molecules, each capture molecule being capable of binding to a specific biomarker from at least one of the four major regions of the renal tubule, in particular the proximal, distal, collecting duct and loop of Henle regions, the detection of one or more biomarkers in the urine sample being indicative of damage in a corresponding region of the renal tubule. The method facilitates inter alia the non-invasive detection of renal tubule damage and serves as a prognostic method to determine the level of tubule damage and monitor the effectiveness of therapeutic treatment.

Abstract: A diesel particulate filter with an oxidation catalyst comprising platinum and palladium deposited thereon is described. Addition of HC storage components to the oxidation catalyst allows the conversion of hydrocarbons and carbon monoxide to be improved significantly.

Abstract: The invention relates generally to the field of cancer detection, diagnosis, subtyping, staging, prognosis, treatment and prevention. More particularly, the present invention relates to methods for the detection, and/or diagnosing and/or subtyping and/or staging of lung cancer in a patient. Based on a particular panel of biomarkers, the present invention provides methods to detect, diagnose at an early stage and/or differentiate small cell lung cancer (SCLC) from non-small cell lung cancer (NSCLC) and within NSCLC to differentiate between squamous cell carcinomas (SCC), adenocarcinomas (AC), within SCC to discriminate G2 and G3 stage and within lung cancer to differentiate for lung cancers with or without neuroendocrine origin. It further provides the use of said panel of biomarkers in monitoring disease progression in a patient, including both in vitro and in vivo imaging techniques.

Abstract: The present invention provides methods of synthesizing organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.

Abstract: The invention relates to a contact element for a connecting terminal, where the contact element consists of a bent punched part, into which are integrated at least an initial clamping means for fixing a plug link into position and a second clamping means for fixing a connecting pin into position. The invention also relates to a connecting terminal, particularly a circuit board connecting terminal, with at least two clamping elements, where the clamping elements each have an insulating housing, with a contact element of the described type positioned within said insulating housing. Finally, the invention relates to a plug link for such a connecting terminal.

Abstract: The invention relates to a connecting terminal with an insulating housing and a clamping contact positioned in the connecting terminal housing for the purpose of connecting an electrical conductor, such that a contact spring, which is electrically connected to the clamping contact in the housing, is guided through an initial hole in the housing of connecting terminal to the outside of the housing, and where the contact spring is so designed that it presses against the contact surface of the circuit board when the connecting terminal is mounted on a circuit board, to thereby produce an electrical contact between the circuit board and the clamping contact.

Abstract: A diesel particulate filter with an oxidation catalyst comprising platinum and palladium deposited thereon is described. Addition of HC storage components to the oxidation catalyst allows the conversion of hydrocarbons and carbon monoxide to be improved significantly.

Abstract: The invention relates to a contact element for printed circuit boards, comprising a terminal body that has an insertion opening for the insertion of a conductor and a screw for the fastening by clamping of the conductor within the terminal body. A seating element with a seating surface is detachably fastenable by a fastening element to the contact element. The seating surface has a surface area that is greater than the cross-sectional surface area of the terminal body.

Abstract: An improvement to kite control systems for power kites, comprising at least one proportional redirection mechanism, which balances the forces of the main lifting force of the kite and the control handlebar, thus assisting with steering the kite and significantly reducing the effort needed to hold or pull the control handlebar, without taking away the flexibility to instantly depower the kite. A compound pulley system can be used as a proportional redirection device as described in one embodiment, or levers can used as shown in an alternative embodiment.

Abstract: The invention relates to a radiation-curable precious-metal preparation, in particular a bright-gold preparation, that contains—in addition to a gold compound, which in particular is soluble in the printing medium, and further customary organometallic compounds—a radiation-curable, in particular UV-curable, printing medium, the polymerisation being initiated by the UV radiation and proceeding in accordance with a cationic mechanism which may optionally be assisted by y process that takes place simultaneously in accordance with a radical mechanism. The invention also relates to a transfer picture containing the precious-metal preparation, and to a process for decorating substrates that are suitable for decoration firing by direct application/printing and indirect printing (decalcomania).

Abstract: A method and system are provided for enhancing streaming operation in a distributed communication system providing communication links between a plurality of stream servers, a client machine requesting a particular media file, and, a stream server selection unit. First, a list of stream servers is retrieved. Then, the list is evaluated and one of the stream servers is selected as the best-suited stream server. Finally, streaming from the selected stream server is initiated.

Abstract: The invention relates to a single terminal (10, 110) with a terminal body (20, 120) designed in the shape of a frame and made of an electrically conductive material, with at least one connection pin (27, 127) being arranged on one exterior side (20, 120) and a clamping spring (30, 130) being inserted in the terminal body (20, 120).