Abstract: A control system for a vehicle having a seat with a first moveable portion and an adjustment actuator coupled with the first moveable seat portion includes a voice input device, a touchscreen input device, and a controller in communication with the adjustment actuator, the voice input device, and the touchscreen input device. The controller has a processor programed to interpret a first adjustment command from one of a voice command received from the voice input device and a manual command received from the touchscreen input device, carry out a first seat adjustment by causing the adjustment actuator to move the first moveable seat portion according to the first adjustment command, and to present information related to the first adjustment command on the touchscreen.

Abstract: The invention relates to a CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers; a pharmaceutical formulation, pharmaceutical composition and kit comprising said CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers, and use of said CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers. For example, the compounds of the invention are useful for reducing or inhibiting the activity of CDK4/6 kinase in a cell, and/or treating and/or preventing a cancer-related disease mediated by CDK4/6 kinase.

Abstract: The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R1, R2, R3, R4, R5, R6, R7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.

Abstract: According to one or more embodiments, a seat climate control assembly for a seat includes a seatback and a headrest, the seat climate control assembly includes an air intake port positioned on a top portion of the seatback and in fluid communication with the headrest, and an air controller in fluid communication with the air intake port.

Abstract: The present invention in one or more embodiments provides a compartment panel assembly to be positioned between one or more seats and a trunk storage of a vehicle. The compartment panel includes a panel portion, a protruding portion extending from the panel portion and including a first wall which defines thereupon a first aperture, and a first storage container to be at least partially received through the first aperture. The present invention in one or more embodiments is advantageous positioned in providing effective storage within the vehicle interior, and in particular providing storage spaces that are lockable and/or not directly visible for enhanced storage security.

Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.

Abstract: The present invention belongs to the field of pharmaceutical technology, more specifically relates to optically pure benzyl-4-chlorophenyl-C-glucoside derivatives represented by formulae (II) and (III), a process for preparing these compounds and intermediates thereof, a pharmaceutical formulation and a pharmaceutical composition containing these compounds, and the use of the optically pure benzyl-4-chlorophenyl-C-glucoside derivative as a sodium glucose co-transporter (SGLT) inhibitor in manufacture of a medicament for treating and/or preventing diabetes mellitus (including insulin-dependent diabetes mellitus and non-insulin-dependent diabetes mellitus) or diabetes-associated diseases (including insulin resistance disease and obesity)

Abstract: The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt, a stereoisomer or a solvate thereof, wherein R1, R2, R3, R4, X, Y, A and B are as defined in the specification. The present invention further relates to a method for preparing these compounds, a pharmaceutical composition containing these compounds, and a use of these compounds in manufacture of a medicament for treating and/or preventing proliferative diseases.

Abstract: The present invention relates to a biaryl heterocycle substituted oxazolidinone antibacterials shown by general formula (I), a pharmaceutically acceptable salt thereof, an isomer or a prodrug thereof, wherein R1, R2, R3, R4, R5, A and B are as defined in the description. The present invention further relates to a method for preparing the compound, a pharmaceutical composition and a pharmaceutical formulation comprising the compound, and a use of the compound in the manufacture of a medicament for the treatment and/or prevention of infectious diseases and a use for the treatment and/or prevention of infectious diseases.

Abstract: Disclosed are bicyclic group substituted pyrimidine compounds, pharmaceutical acceptable salts thereof or stereoisomers thereof. Also disclosed are preparation methods, pharmaceutical formulations, and pharmaceutical compositions of the compounds, and use of the compounds, pharmaceutical formulations, and pharmaceutical compositions for preparing a medicament for treating and/or preventing sexual dysfunction diseases and diseases with lower urinary tract symptoms.

Abstract: The present invention belongs to the field of pharmaceutical technology, more specifically relates to optically pure benzyl-4-chlorophenyl-C-glucoside derivatives represented by formulae (II) and (III), a process for preparing these compounds and intermediates thereof, a pharmaceutical formulation and a pharmaceutical composition containing these compounds, and the use of the optically pure benzyl-4-chlorophenyl-C-glucoside derivative as a sodium glucose co-transporter (SGLT) inhibitor in manufacture of a medicament for treating and/or preventing diabetes mellitus (including insulin-dependent diabetes mellitus and non-insulin-dependent diabetes mellitus) or diabetes-associated diseases (including insulin resistance disease and obesity)

Abstract: The present invention in one or more embodiments provides a compartment panel assembly to be positioned between one or more seats and a trunk storage of a vehicle. The compartment panel includes a panel portion, a protruding portion extending from the panel portion and including a first wall which defines thereupon a first aperture, and a first storage container to be at least partially received through the first aperture. The present invention in one or more embodiments is advantageous positioned in providing effective storage within the vehicle interior, and in particular providing storage spaces that are lockable and/or not directly visible for enhanced storage security.

Abstract: The present application relates to a compound as represented by general formula (I), a pharmaceutically acceptable salt, ester, solvate or stereoisomer thereof, preparation method of the compounds, a pharmaceutical composition containing the compounds, uses thereof in the preparation of drugs for treating and/or preventing proliferative diseases, and a method using the compounds to treat and/or prevent proliferative diseases. R1, R2, R3, R4, R5, R6, X, A and B in the formula are as defined in the specification.

Abstract: A sous-vide circulator cooker for home sous-vide cooking. The sous-vide circulator cooker is particularly suited for use in home kitchens and on small countertops. The sous-vide circulator cooker includes a detachable stainless steel skirt which allows for cleaning the skirt itself and cleaning of a heater and pump covered by the skirt. The provision of a stainless steel skirt can also act to ensure that no plastic components are directly wetted during use of the cooker. In at least one embodiment, the sous-vide circulator cooker's removable skirt also exposes the water pump impellers allow users to clean out food and debris.

Abstract: A rotary evaporator configured to communicate to connected devices. In at least one embodiment, the communication between the rotary evaporator and the connected devices can be wireless. Additionally, the rotary evaporator can be configured such that one or more of the components of the rotary evaporator are modular. One or more of the components of the rotary evaporator can be replaceable.

Abstract: The present invention pertains to field of medical technology, specifically relates to a pyridino-oxopyridazine derivative of formula (I), its pharmaceutically acceptable salts, its stereoisomers or its solvates, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R7?, R8?, R9?, L and ring A are defined as the description; the present invention further relates to methods for preparing the compounds, a pharmaceutical composition comprising the compound, and use of the compound and the pharmaceutical composition in manufacture of a medicament for treatment and/or prophylaxis of an inflammatory disease, symptom and condition characterized in undesired inflammatory immunoreaction or associated with undesired inflammatory immunoreaction, as well as all diseases induced by oversecretion of TNF-? and PDE-4 or associated with oversecretion of TNF-? and PDE-4.

Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.

Abstract: According to one or more embodiments, a seat climate control assembly for a seat includes a seatback and a headrest, the seat climate control assembly includes an air intake port positioned on a top portion of the seatback and in fluid communication with the headrest, and an air controller in fluid communication with the air intake port.

Abstract: The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt, a stereoisomer or a solvate thereof, wherein R1, R2, R3, R4, X, Y, A and B are as defined in the specification. The present invention further relates to a method for preparing these compounds, a pharmaceutical composition containing these compounds, and a use of these compounds in manufacture of a medicament for treating and/or preventing proliferative diseases.

Abstract: Disclosed are bicyclic group substituted pyrimidine compounds, pharmaceutical acceptable salts thereof or stereoisomers thereof. Also disclosed are preparation methods, pharmaceutical formulations, and pharmaceutical compositions of the compounds, and use of the compounds, pharmaceutical formulations, and pharmaceutical compositions for preparing a medicament for treating and/or preventing sexual dysfunction diseases and diseases with lower urinary tract symptoms.