Patents by Inventor Franz Esser

Franz Esser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurokinin antagonists
    Publication number: 20020115666
    Abstract: The invention relates to new compounds of formula I 1
    Type: Application
    Filed: October 16, 2001
    Publication date: August 22, 2002
    Inventors: Horst Dollinger, Franz Esser, Birgit Jung, Gerd Schnorrenberg, Kurt Schromm, Georg Speck
  • New arylglycinamide derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds
    Publication number: 20020086863
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I 1
    Type: Application
    Filed: October 5, 2001
    Publication date: July 4, 2002
    Applicant: Boehringer Ingelheim KG.
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Method of treating depression with arylglycinamide derivatives
    Patent number: 6413959
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I and the pharmaceutically acceptable salts thereof, wherein R1 and R2 together with the N to which they are bound form a ring of the formula wherein p is 2 or 3 and X denotes oxygen, N(CH2)nR6 or CR7R8, and R3, R4, R5, R6, R7, R8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: July 2, 2002
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • SKIN TREATMENT COMPOSITONS CONTAINING A CATIONIC POLYMER AND A MICROPARTICLE OR NANOPARTICLE VECTOR
    Publication number: 20020040150
    Abstract: The present invention relates to the use of &agr;1L-agonists for treating urinary incontinence.
    Type: Application
    Filed: March 28, 2000
    Publication date: April 4, 2002
    Inventors: Franz Esser, Helmut Stahle, Sven Luttke, Ikonobu Muramatsu, Hisato Kitagawa, Shujil Uchida
  • Arylgycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds
    Patent number: 6303601
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I and the pharmaceutically acceptable salts thereof, wherein R1 and R2 together with the N to which they are bound form a ring of the formula  wherein is 2 or 3 and X denotes oxygen, N(CH2)nR6 or CR7R8, and R34 R5 R6 R7, R8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: January 3, 2001
    Date of Patent: October 16, 2001
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Arylglycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds
    Patent number: 6294556
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I and the pharmaceutically acceptable salts thereof, wherein R1 and R2 together with the N to which they are bound form a ring of the formula  wherein p is 2 or 3 and X denotes oxygen, N(CH2)nR6 or CR7R8, and R3, R4, R5, R6, R7, R8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: September 25, 2001
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Neurokinin antagonists, processes for preparing them and pharmaceutical compositions containing these compounds
    Patent number: 6277840
    Abstract: The invention relates to new compounds of general formula I or the pharmaceutically acceptable salts thereof, wherein X=N—R3 or CH—R4, Y=CH2 or (CH2)2, Z=O or H2; and R1, R2, R3, R4 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: August 21, 2001
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Sven Luettke, Birgit Jung, Georg Speck
  • Arylgycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds
    Publication number: 20010011093
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I 1
    Type: Application
    Filed: January 3, 2001
    Publication date: August 2, 2001
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Treatment of urinary incontinence by administration of &agr;1L-adrenoceptor agonists
    Patent number: 6268389
    Abstract: The present invention relates to the use of &agr;lL-agonists for treating urinary incontinence.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: July 31, 2001
    Assignee: Boehringer Ingelheim KG
    Inventors: Franz Esser, Helmut Staehle, Sven Luettke, Ikunobu Muramatsu, Hisato Kitagawa, Shuji Uchida
  • Arylglycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds
    Patent number: 6251909
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I and the pharmaceutically acceptable salts thereof, wherein R1 and R2 together with the N to which they are bound form a ring of the formula  wherein p is 2 or 3 and X denotes oxygen, N(CH2)nR6 or CR7R8, and R3, R4, R5, R6, R7, R8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: June 26, 2001
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Dipeptides with neurokinin-antagonistic activity
    Patent number: 6232468
    Abstract: Disclosed are compounds which are neurokinin (tachykinin)-antagonists, useful for the treatment or prevention of inflammatory and allergic disease.
    Type: Grant
    Filed: December 1, 1999
    Date of Patent: May 15, 2001
    Assignee: Boehringer Ingelheim KG
    Inventors: Franz Esser, Gerd Schnorrenberg, Hans-Peter Ignatow, Günther Giesler, Birgit Jung, Georg Speck
  • Amino acid derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds
    Patent number: 6147212
    Abstract: The invention relates to new amino acid derivatives of general formula I and the pharmaceutically acceptable salts thereof, wherein group B is --A.sup.2 --NR.sup.2 R.sup.3 or R.sup.5, wherein group R.sup.5 is ##STR1## and R.sup.1, A.sup.1, A.sup.2, R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.9, X, Y, Z, t and u have the meanings described in the specification, as well as the preparation and use thereof. The novel compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: July 8, 1998
    Date of Patent: November 14, 2000
    Assignee: Boehringer Ingelheim KG
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Birgit Jung, Erich Burger
  • Arylglycinamide derivatives, methods of producing these substances and pharmaceutical compositions containing such compounds
    Patent number: 6124296
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1 and R.sup.2 together with the N to which they are bound form a ring of the formula ##STR2## wherein p is 2 or 3 andX denotes oxygen, N(CH.sub.2).sub.n R.sup.6 or CR.sup.7 R.sup.8,and R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, Ar and n have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: October 29, 1997
    Date of Patent: September 26, 2000
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Arylglycinamide derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds
    Patent number: 6121262
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokin (tachykinin) antagonists.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: September 19, 2000
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Neurokinin antagonists, processes for preparing them and pharmaceutical compositions containing these compounds
    Patent number: 6103719
    Abstract: The invention relates to new compounds of general formula I ##STR1## or the pharmaceutically acceptable salts thereof, wherein X=N--R.sup.3 or CH--R.sup.4,Y=CH.sub.2 or (CH.sub.2).sub.2,Z=O or H.sub.2 ;and R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: May 27, 1999
    Date of Patent: August 15, 2000
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Sven Luettke, Birgit Jung, Georg Speck
  • Amino acid derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
    Patent number: 5922878
    Abstract: The invention relates to new amino acid derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein the group R.sup.2 is ##STR2## and R.sup.1, A, G, Y, Z and m have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: July 13, 1999
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Brigit Jung, Erich Burger, Georg Speck
  • Arylglycinamide derivatives and pharmaceutical compositions containing these compounds
    Patent number: 5861509
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokin (tachykinin) antagonists.
    Type: Grant
    Filed: October 9, 1997
    Date of Patent: January 19, 1999
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Amino acid derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds
    Patent number: 5849918
    Abstract: The invention relates to new amino acid derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein group B is --A.sup.2 --NR.sup.2 R.sup.3 or R.sup.5, wherein group R.sup.5 is ##STR2## and R.sup.1, A.sup.1, A.sup.2, R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.9, X, Y, Z, t and u have the meanings described in the specification, as well as the preparation and use thereof. The novel compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 15, 1998
    Assignee: Boehringer Ingelheim KG
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Birgit Jung, Erich Burger
  • Amino acid derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
    Patent number: 5807875
    Abstract: Amino acid derivatives, suitable for the treatment of obesity. The following compound is exemplary of the class: (R,S)-N.sup.2 -(diphenylacetyl)-N-?(4-hydroxyphenyl)methyl!-N.sup.5 -(1H-imidazol-2-yl)-ornithinamide.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: September 15, 1998
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Klaus Rudolf, Wolfgang Eberlein, Wolfhard Engel, Gerhard Mihm, Henri Doods, Heike Andrea Wieland, Klaus-Dieter Willim, Jurgen Krause, Horst Dollinger, Franz Esser, Gerd Schnorrenberg, Michael Entzeroth, Wolfgang Wienen
  • Amino acid derivatives, processes for the manufacture thereof and pharmaceutical compositions (II) containing these compounds
    Patent number: 5712273
    Abstract: The invention relates to new amino acid derivatives of general formula IR.sup.1 -R.sup.11 --A.sup.1 --B (I)and the pharmaceutically acceptable salts thereof, wherein group B is --A.sup.2 --NR.sup.2 R.sup.3 or R.sup.5, and whereinR.sup.1, A.sup.1, A.sup.2, R.sup.2, R.sup.3, R.sup.5 and R.sup.11 have the meanings described in the specification, as well as the preparation and use thereof. The novel compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: January 27, 1998
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerd Schnorrenberg, Franz Esser, Horst Dollinger, Birgit Jung, Georg Speck, Erich Burger