Patents by Inventor Franz Esser

Franz Esser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amino acid derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
    Patent number: 5712397
    Abstract: The invention relates to new amino acid derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein the group R.sup.2 is ##STR2## and R.sup.1, A, G, Y, Z and m have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin)-antagonists.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 27, 1998
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Birgit Jung, Erich Burger, Georg Speck
  • Arylglycinamide derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds
    Patent number: 5710155
    Abstract: The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokin (tachykinin) antagonists.
    Type: Grant
    Filed: July 30, 1996
    Date of Patent: January 20, 1998
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Horst Dollinger, Franz Esser, Hans Briem, Birgit Jung, Georg Speck
  • Amino acid derivatives, processes for the manufacture thereof and pharmaceutical compositions (II) containing these compounds
    Patent number: 5700827
    Abstract: The invention relates to new amino acid derivatives of general formula IR.sup.1 --R.sup.11 --A.sup.1 B (I)and the pharmaceutically acceptable salts thereof, wherein group B is --A.sup.2 --NR.sup.2 R.sup.3 or R.sup.5, and whereinR.sup.1, A.sup.1, A.sup.2, R.sup.2, R.sup.3, R.sup.5 and R.sup.11 have the meanings described in the specification, as well as the preparation and use thereof. The novel compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 23, 1997
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerd Schnorrenberg, Franz Esser, Horst Dollinger, Birgit Jung, Georg Speck, Erich Burger
  • Amino acid derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of obesity
    Patent number: 5616620
    Abstract: Amino acid derivatives, suitable for the treatment of obesity. The following compound is exemplary of the class: (R)-N2-(diphenylacetyl)-N-[(4-hydroxyphenyl) methyl]-argininamide-acetate.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: April 1, 1997
    Assignee: Karl Thomae GmbH
    Inventors: Klaus Rudolf, Wolfgang Eberlein, Wolfhard Engel, Gerhard Mihm, Henri Doods, Heike A. Wieland, Klaus-Dieter Willim, Jurgen Krause, Horst Dollinger, Franz Esser, Gerd Schnorrenberg, Michael Entzeroth, Wolfgang Wienen
  • Amino acid derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds
    Patent number: 5596000
    Abstract: The invention relates to new amino acid derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein group B is --A.sup.2 --NR.sup.2 R.sup.3 or R.sup.5, wherein group R.sup.5 is ##STR2## and R.sup.1, A.sup.1, A.sup.2, R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.9, X, Y, Z, t and u have the meanings described in the specification, as well as the preparation and use thereof. The novel compounds are valuable neurokinin (tachykinin) antagonists.
    Type: Grant
    Filed: September 2, 1993
    Date of Patent: January 21, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Franz Esser, Gerd Schnorrenberg, Horst Dollinger, Birgit Jung, Erich Burger
  • Feed additive for improving growth in agricultural animals
    Patent number: 5135929
    Abstract: By using .sub..alpha. -mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilization of fodder and the ratio of muscle to fat in favor of the proportion of muscle and protein.
    Type: Grant
    Filed: September 5, 1990
    Date of Patent: August 4, 1992
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Werner Bomann, Franz Esser, Ulrich Hamel, Helmut Stable
  • Aryloxy-aminoalkanes, and antihypertensive use thereof
    Patent number: 4997833
    Abstract: Aryloxy-aminoalkanes useful as antihypertensive agents are described and disclosed.
    Type: Grant
    Filed: July 5, 1989
    Date of Patent: March 5, 1991
    Assignee: Boehringer Ingelheim K G
    Inventors: KoHerbert, Franz Esser, Wolfram Gaida, Wolfgang Hoefke, Georg Speck
  • Feed additive for improving growth in agricultural animals
    Patent number: 4970208
    Abstract: By using .alpha.-mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilization of fodder and the ratio of muscle to fat in favour of the proportion of muscle and protein.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: November 13, 1990
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Werner Bomann, Franz Esser, Ulrich Hamel, Helmut Stable
  • 1-phenoxy-3-amino-2-propanols use thereof
    Patent number: 4948812
    Abstract: Compounds of formula ##STR1## (the substituents R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are explained in the specification) may be prepared by conventional methods.Owing to their favorable activity profile the compounds may advantageously be used to treat certain heart and circulatory disorders.
    Type: Grant
    Filed: November 25, 1987
    Date of Patent: August 14, 1990
    Assignee: Boehringer Ingelheim KG
    Inventors: Herbert Koppe, Franz Esser, Walter Kobinge, Christian Lillie
  • Feed additive for improving growth in agricultural animals
    Patent number: 4853402
    Abstract: By using .alpha.-mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilisation of fodder and the ratio of muscle to fat in favor of the proportion of muscle and protein.
    Type: Grant
    Filed: February 26, 1987
    Date of Patent: August 1, 1989
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Werner Bomann, Franz Esser, Ulrich Hamel, Helmut Stable
  • 1-aryloxypropanolamines
    Patent number: 4594344
    Abstract: Disclosed are novel compounds having the formula ##STR1## wherein R.sub.1 is a hydrogen or halogen atom, a lower alkyl, lower alkoxy, lower alkoxy lower alkyl, lower alkenyl, lower alkenyl oxy, cyano, hydroxy, trifluoromethyl, nitro, amino, aminocarbonylmethyl, lower monoalkylamino, lower dialkylamino group;R.sub.2 is a hydrogen or halogen atom, cyano, lower alkyl or lower alkoxy or acylamino group;R.sub.3 is a hydrogen or halogen atom, a lower alkyl or lower alkoxy group, while R.sub.2 and R.sub.3 together can also be a butadienyl or methylene dioxy group;R.sub.4 is a hydrogen atom or a lower alkyl group;R.sub.5 is a chlorine atom or a trifluoromethyl group;X is an alkylene group;and the non-toxic, pharmaceutically acceptable acid addition salts thereof.The compounds are suitable for treatment and prophylaxis of hypertension.
    Type: Grant
    Filed: July 15, 1985
    Date of Patent: June 10, 1986
    Assignee: Boehringer Ingelheim KG
    Inventors: Herbert Koppe, Wolfgang Abele, deceased, Franz Esser, Wolfram Gaida, Wolfgang Hoefke
  • Analgesic 1-acetonyl-2-(phenylimino)-imidazolidines and salts thereof
    Patent number: 4588736
    Abstract: Compounds of the formula ##STR1## wherein X, Y and Z are each independently hydrogen, halogen, lower alkyl, halo(lower alkyl), lower alkoxy, halo(lower alkoxy), (lower alkyl)thio or halo(lower alkyl)thio, orY and Z, together with each other, are lower alkylenedioxy;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as analgesics.
    Type: Grant
    Filed: May 21, 1984
    Date of Patent: May 13, 1986
    Assignee: Boehringer Ingelheim KG
    Inventors: Franz Esser, Herbert Koppe, Wolfgang Abele, Klaus Stockhaus
  • Substituted 1-(.alpha.-aminocarbonyl-benzyl)-3,4-dihydro-isoquinolines, compositions and use
    Patent number: 4322418
    Abstract: This invention relates to substituted 1-(.alpha.-aminocarbonyl-benzyl)-3,4-dihydro-isoquinolines in the racemic or optically active form and the non-toxic pharmacologically acceptable salts thereof. These compounds are useful in the promotion of blood circulation in warm-blooded animals.
    Type: Grant
    Filed: April 3, 1981
    Date of Patent: March 30, 1982
    Assignee: C. H. Boehringer Sohn
    Inventors: Walter Losel, Franz Esser, Otto Roos, Richard Reichl, Franz J. Kuhn, Werner Traunecker