Abstract: Drug combinations, compositions including pharmaceutical compositions as well as methods of using and treating a viral infection, including one of the following: (1) atovaquone with a second group of substances consisting of ademetionine, albendazole, celastrol, cepharantine, chloroquine, cycloheximide, diethylstilbestrol, gemcitabine, homoharringtonine, hydroxy progesterone, imatinib, imipramine, indomethacin, ivermectin, niclosamide, raloxifene, sorafenib, and tipifarnib; or (2) cepharantine with a second group of substances consisting of ademetionine, albendazole, atovaquone, celastrol, chloroquine, cycloheximide, diethylstilbestrol, gemcitabine, homoharringtonine, hydroxy progesterone, imatinib, imipramine, indomethacin, ivermectin, raloxifene, sorafenib, and tipifarnib; or (3) one substance selected from a first group of substances consisting of ademetionine, albendazole, atovaquone, celastrol, cepharantine, chloroquine, cycloheximide, diethylstilbestrol, gemcitabine, homoharringtonine, hydroxy progester

Abstract: Drug combinations, compositions including pharmaceutical compositions as well as methods of using and treating a viral infection, the drug combinations including (1) protease inhibitors Camostat, Nafamostat, (2) modulators or inhibitors of intracellular steroid hormone receptors signaling pathways (steroid hormone receptor antagonists), (3) modulators or inhibitors of SKP2 protein, (4) modulators of poly(ADP-ribose) polymerases and (5) angiotensin 2 response modifiers.

Abstract: The invention relates to an electrotechnical coil, to a method for producing same, and to an electromagnet or an electric machine comprising at least one such coil. The aim of the invention is to produce and use an electrotechnical coil for achieving an increased slot fill factor reliably and easily in a reproducible and economical manner. This is achieved in that the method according to the invention has the steps: step A: casting an electrotechnical coil with at least one winding which runs about a coil axis; and step B: shaping the coil, thereby changing the cross-section Q, Q? of the at least one winding, such that the centroid FS, FS? of the cross-section Q, Q? of the at least one winding is displaced at least partly in the radial direction R relative to the coil axis A.

Abstract: The industrial production of an extract by means of solid-liquid extraction improves the exchange of substances during extraction and allows enhanced dehumidification of a raffinate with residual moisture. The extraction is enhanced during a first dwell time by at least partially flooding a vessel in the form of at least one flow discharged with a secondary solvent or the obtained extract, swirling and keeping in suspension the primary mixture within the vessel by supplying the secondary solvent or the obtained extract via a foot area of the vessel, and/or moving the vessel relative to the extraction container within the obtained extract. The secondary solvent or the extract circulates in the extraction container by a circulation guide incorporating the extraction container from top to bottom relative to the extraction container, and the extract freed from raffinate with residual moisture obtained by dehumidification is supplied to the separated or to be separated extract.

Abstract: The disclosed subject matter relates to the construction and use of novel proteomics-based descriptor sets for analyzing high throughput proteomics derived pathogen-host interactome information and the use of these descriptor sets for identifying substances and substance combinations that have utility for treating and or preventing infections and diseases caused by a broad range of pathogens of diverse origins.

Abstract: Controlling the production of an extract using solid-liquid extraction that improves the exchange of material during the extraction process and allows a controlled dehumidification of a raffinate with residual moisture in order to obtain additional valuable extract is described. The steps include providing a first mass in an extraction container, supplying a second mass to the first mass without spatial constraints and distributing and mixing the second mass into and with the first mass, discharging a mixture of the extract and the raffinate from the extraction container, separating the discharged mixture into the raffinate with residual moisture and extracts released from the raffinate with residual moisture, and further treating the raffinate with residual moisture at least such that the residual moisture consisting of the extract is at least partly removed from the raffinate with residual moisture by dehumidification and is supplied to the already separated extract.

Abstract: An airfoil for disposition and exposure to flow in a hot gas duct of a turbomachine is provided. The airfoil has a suction-side wall and a pressure-side wall with respect to its exposure to the flow in the gas duct, the side walls converging in an upstream end region toward a leading edge and converging in a downstream end region toward a trailing edge. The airfoil further has a cavity structure therein which is enclosed between an inner wall surface of the suction-side wall and an inner wall surface of the pressure-side wall when viewed in a cross-sectional plane axially parallel to a longitudinal axis of the turbomachine. When viewed in the cross-sectional plane, at least one of the inner wall surfaces, normalized to a mean camber line of the airfoil as a reference, extends with a change in curvature into at least one of the end regions in such a way that a clearance width of the cavity structure is increased at the at least one end region.

Abstract: The present disclosure relates to pharmaceutical compositions, pharmaceutical combinations and methods of treatment including zileuton, edaravone and atorvastatin compounds combined with nephrotoxicity-inducing antibiotic or anticancer drugs for treating bacterial infections and cancers.

Abstract: A method of tracking information flows through multiple network systems includes selecting a primary network system from a population of primary and secondary network systems, wherein each of the primary and secondary network systems include network nodes, selecting first selected characteristic features that identify network nodes of the primary network system that provide interaction between the selected primary network system and secondary network systems, identifying at least one secondary network system that is capable of interacting with the network nodes of the primary network system, subdividing the primary network into subnetwork systems based on identifying primary network nodes that provide interaction between the primary network system and secondary network nodes, identifying the subnetwork systems that are capable of interacting with one or more network nodes of the secondary network systems, identifying a subnetwork node count of the primary network nodes in each subnetwork, identifying objects

Abstract: The invention relates to an electrotechnical coil, to a method for producing same, and to an electromagnet or an electric machine comprising at least one such coil. The aim of the invention is to produce and use an electrotechnical coil for achieving an increased slot fill factor reliably and easily in a reproducible and economical manner. This is achieved in that the method according to the invention has the steps: step A: casting an electrotechnical coil with at least one winding which runs about a coil axis; and step B: shaping the coil, thereby changing the cross-section Q, Q? of the at least one winding, such that the centroid FS, FS? of the cross-section Q, Q? of the at least one winding is displaced at least partly in the radial direction R relative to the coil axis A.

Abstract: An airfoil for disposition and exposure to flow in a hot gas duct of a turbomachine is provided. The airfoil has a suction-side wall and a pressure-side wall with respect to its exposure to the flow in the gas duct, the side walls converging in an upstream end region toward a leading edge and converging in a downstream end region toward a trailing edge. The airfoil further has a cavity structure therein which is enclosed between an inner wall surface of the suction-side wall and an inner wall surface of the pressure-side wall when viewed in a cross-sectional plane axially parallel to a longitudinal axis of the turbomachine. When viewed in the cross-sectional plane, at least one of the inner wall surfaces, normalized to a mean camber line of the airfoil as a reference, extends with a change in curvature into at least one of the end regions in such a way that a clearance width of the cavity structure is increased at the at least one end region.

Abstract: In the present invention a new solar photovoltaic module is proposed comprising a solar cell comprising a silicon layer having a first surface and a second surface opposite to said first surface. The solar cell further comprises a passivating layer stack comprising a heterogeneous layer arranged on said first surface and/or on said second surface. The heterogeneous layer, having a back surface and a front surface, comprises a non-conducting matrix having a refractive index being lower than 3.0. The heterogeneous layer further comprises inclusions of at least one conductive material in said matrix, and at least some of said inclusions extend from said back surface to said front surface of the heterogeneous layer for electrically connecting the surfaces of the heterogeneous layer.

Abstract: The invention is directed to a class of compounds, including the pharmaceutically acceptable salts of the compounds, having the structure of formula I: as defined in the specification. The invention is also directed to compositions containing and uses of the compounds of formula I.

Abstract: The aspects of the disclosed embodiments are directed to novel compounds, formulations containing said compounds or pharmaceutically acceptable salts thereof which are suitable for administration to a patient.

Abstract: A method of tracking information flows through multiple network systems includes selecting a primary network system from a population of primary and secondary network systems, wherein each of the primary and secondary network systems include network nodes, selecting first selected characteristic features that identify network nodes of the primary network system that provide interaction between the selected primary network system and secondary network systems, identifying at least one secondary network system that is capable of interacting with the network nodes of the primary network system, subdividing the primary network into subnetwork systems based on identifying primary network nodes that provide interaction between the primary network system and secondary network nodes, identifying the subnetwork systems that are capable of interacting with one or more network nodes of the secondary network systems, identifying a subnetwork node count of the primary network nodes in each subnetwork, identifying objects

Abstract: The aspects of the disclosed embodiments are directed to novel compounds, specifically, quaternary ammonium derivatives of tertiary amine containing opioid drug compounds such as hydrocodone, hydromorphone and oxycodone, formulations containing said. compounds or pharmaceutically acceptable salts thereof, which are capable of providing controlled release of the opioid drug upon administration to a patient in order to treat pain.

Abstract: An image forming apparatus includes: an image reading section, an operating section; a synthesizing region acceptance section that accepts, through the touch panel, specification of an object synthesizing region of a document image acquired by reading by the image reading section; an object acquiring section that acquires a plurality of objects to be individually synthesized in the object synthesizing region; and an image creating section that synthesizes each of object images representing the acquired objects in the object synthesizing region of the document image, thus creating, for the plurality of objects, individual outputting synthetic images containing the respective object images synthesized thereinto.

Abstract: An image processing apparatus includes a job processing portion, a first communication portion, a second communication portion, a job control portion. In the image processing apparatus, the first communication portion performs first wireless communication being proximity-type wireless communication. The second communication portion performs second wireless communication whose communicable distance is longer than that of the first wireless communication and whose communication speed is faster than that of the first wireless communication. After the first communication portion automatically establishes communication connection between the first communication portion and a transmission source of the signal through the first wireless communication, the first communication portion hands over the communication connection to second wireless communication.

Abstract: The invention is directed to a class of compounds, including the pharmaceutically acceptable salts of the compounds, having the structure of formula I: as defined in the specification. The invention is also directed to compositions containing and uses of the compounds of formula I.

Abstract: An image processing apparatus includes a job processing portion, a first communication portion, a second communication portion, a job control portion. In the image processing apparatus, the first communication portion performs first wireless communication being proximity-type wireless communication. The second communication portion performs second wireless communication whose communicable distance is longer than that of the first wireless communication and whose communication speed is faster than that of the first wireless communication. After the first communication portion automatically establishes communication connection between the first communication portion and a transmission source of the signal through the first wireless communication, the first communication portion hands over the communication connection to second wireless communication.