Abstract: Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R1, Y, and p are disclosed herein.

Abstract: Disclosed are compounds and compositions of Formula (I), pharmaceutically acceptable salts and solvates thereof, and their uses for treating viral infections mediated at least in part by a virus in the Flaviviridae family of viruses.

Abstract: Disclosed are compounds having Formula (I) and the compositions and methods relating to these compounds, for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R1, Y, and p are disclosed herein.

Abstract: A convertible vehicle with a roof can be folded down under a cover part in a rear section of the vehicle. The cover part can be opened in a first direction to release an opening for luggage and in a second direction to release an opening for the roof. The vehicle includes a movement mechanism to hold the cover part and further includes at least one multi-link chain. The multi-link chain includes a plurality of hinges for the movement of the cover part. At least one of the plurality of hinges is held in an idle state when the cover part is opened in the first direction and the second direction.

Abstract: An apparatus includes a sensor body, a circuit board, a cable, at least one light emitting device, and at least one photodetector. The circuit board is enclosed within the sensor body and includes at least one conductive trace and at least one aperture. The cable is coupled to the at least one conductive trace. The cable includes a shield conductor and a signal conductor. The at least one light emitting device is coupled to the circuit board and is configured to emit light into a tissue. The at least one photodetector includes a planar active area coupled to the circuit board and is configured to provide an output signal based on light detected by the active area. The planar active area is aligned with the aperture. The output signal is coupled to the cable.

Abstract: A convertible vehicle with a roof that can be stowed in the rear area of the vehicle, wherein when the roof is closed, an area in front of the rear roof seal relative to the direction of travel and below a rear window can be at least partially covered by a cover in the manner of a rear shelf, the cover being recessed when the roof is opened. The cover comprises a center section and outer sections situated to its sides in relation to the transverse direction of the vehicle, which, when the roof is open, are folded in relative to the center section in an at least nearly opposite orientation.

Abstract: Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R1, Y, and p are disclosed herein.

Abstract: Provided are compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds and compositions are useful for treating viral infections caused by the Flaviviridae family of viruses.

Abstract: Disclosed are compounds of Formula (I), pharmaceutically acceptable salts and solvates thereof, compositions thereof, and methods for their preparation and uses for treating viral infections mediated at least in part by a virus in the Flaviviridae family of viruses.

Abstract: Provided are certain chemical entities, pharmaceutical compositions, and methods of treatment of a member of the flaviviradae family of viruses such as hepacivirus (Hepatitis C or HCV).

Abstract: Disclosed are compounds, compositions and methods for treating Flaviviridae family virus infections.

Abstract: Disclosed are compounds, compositions and methods for treating Flaviviridae family virus infections.

Abstract: Disclosed are compounds of Formula (I), pharmaceutically acceptable salts and solvates thereof, compositions thereof, and methods for their preparation and uses for treating viral infections mediated at least in part by a virus in the Flaviviridae family of viruses.

Abstract: Aromatic amines which have been obtained by reduction of aromatic nitro compounds are purified by mixing the crude amine obtained after phase separation with an aqueous, alkali metal hydroxide solution and subsequent distillation of this mixture over a distillation column. The distillation column has at least an upper and a lower rectifying part and a stripping part. The bottom product of the distillation column is partly to completely sluiced out and is partly evaporated in a main evaporator and at least one downstream re-evaporator and partly recycled back into the column.

Abstract: The present invention relates to a roll-over protection device for a motor vehicle, particularly for a convertible, comprising a roll bar (2). This roll bar is provided with an at least nearly U-shaped design having a transverse yoke (3) and lateral limbs (4A, 4B) while leaving a loading opening (11) unobstructed, and extending such that it essentially spans the width of the vehicle. The lateral limbs (4A, 4B) can be displaced along fixed guiding devices (6, 7) in order to transfer the roll bar (2) out of a lowered non-operational position and into a raised supporting position. To this end, a central retaining and activating device (12) for the roll bar (2), said device being controlled by an actuator (18), is provided and/or a device (17) that synchronizes the displacement of the limbs (4A, 4B) of the roll bar (2) along the guiding devices (6, 7) is provided.

Abstract: A convertible vehicle according to the present invention includes a vehicle body with a windshield frame with an upper transverse frame part. A convertible roof for the vehicle has a front end.

Abstract: A vehicle roof structure (10), which has at least one rear-side convertible top compartment lid (16) and a rigid roof part (12) movable between an opened- and a closed position, which roof part (12) extends in the closed position between a windshield frame (14) of the vehicle and the convertible top compartment lid (16) and in the opened position is stored in a space underneath the convertible top compartment lid (16), is movable between the closed position and the opened position by a linkage mechanism (30, 36) and is additionally provided with at least one guide device (40, 42, 44), with which the roof part (12) is in contact during at least one portion of its movement path between the opened- and closed position and which effects a directional change of the movement path of the roof part (12) when it arrives in contact with the roof part.

Abstract: A convertible vehicle is provided with at least two roof elements that are separated from each other at a joint when the roof is in the closed position and arranged one after the other relative to the direction of travel, and in order to open the roof a rear roof element can move at least essentially rearward and downward, and a front roof element can swivel toward the rear roof element. When the roof is open, the C pillars can be swiveled inward in relation to a center section comprising to mediate the swiveling, at least one shaft, which when the roof is closed has at least one component in the direction of travel and one upwardly directed component, and whose rotary movement in the region of the joint between the roof elements can be translated into a swivel movement between them.

Abstract: Aromatic amines are produced by adiabatic hydrogenation of nitroaromatic compounds in the gas phase on one or more fixed catalysts. The nitroaromatic reactant is passed over the catalyst under pressure and at elevated temperature with hydrogen, water, optionally nitrogen and substantially in the absence of the aromatic amine produced from the nitroaromatic.

Abstract: The invention relates to a cabriolet vehicle (1) comprising a roof which can be stowed away in the rear of the vehicle, wherein, when the roof is closed, an area which, in the direction of travel (F), is considered as the rear roof part (7) and an area below a rear window (4) is at least partially covered by a rear-window shelf-type cover (8), said cover being lowered when the roof is opened. According to the invention, the cover (8), relative to the vehicle cross-direction, has an intermediate part (9) and lateral outer parts (10) which are folded in, when the roof is closed, relative to the intermediate part (9) into an at least approximately opposite position.