Patents by Inventor Fred E. Cohen

Fred E. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of metazoan parasite proteases
    Patent number: 5739170
    Abstract: Compositions and methods are disclosed for treating a patient infected with a metazoan parasite by inhibiting the enzymatic action of the metazoan parasite protease, wherein there is employed at least one compound of formula IA--X--Bwherein A is a substituted or unsubstituted homoaromatic ring system comprising one to three rings which bind to at least one of the S2, S1 and S1' subsites; B is a substituted or unsubstituted homoaromatic ring system comprising one to three rings which bind to at least one of the S1', S1 and S2 subsites; and X is --C.dbd.C--C(.dbd.O)--. These compositions and methods have particular utility in the treatment of schistosomiasis, malaria, and other infectious diseases.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: April 14, 1998
    Assignee: The Regents of the University of California
    Inventors: Fred E. Cohen, James H. McKerrow, George L. Kenyon, Zhe Li, Xiaowu Chen, Baoqing Gong, Rongshi Li
  • Inhibitors of metazoan parasite proteases
    Patent number: 5610192
    Abstract: Compositions and methods for treating a patient infected with a metazoan parasite by inhibiting the enzymatic action of the metazoan parasite protease. The compositions comprise at least one metazoan protease inhibitor which binds to the S2 subsite and at least one of the S1 and S1' subsites of the metazoan parasite protease. The methods comprise administration to a patient infected with a metazoan parasite of at least one metazoan protease inhibitor in an amount effective to inhibit the protease of the metazoan parasite, thereby killing the parasite.
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: March 11, 1997
    Assignee: The Regents of the University of California
    Inventors: Fred E. Cohen, James H. McKerrow, Christine S. Ring, Philip J. Rosenthal, George L. Kenyon, Zhe Li
  • Wheeled stackable luggage
    Patent number: 5351792
    Abstract: A piece of luggage in the form of a suitcase of a rectangular configuration having a flat top, a flat bottom and flat sides. Four wheels are mounted at the corners of the bottom. Elongated rigid arcuate members are mounted on the corners of the suitcase and each extends from the top of the suitcase to a plane beyond the bottom of the suitcase to protect the wheels. The top of the suitcase is formed of a soft fabric material with a zippered portion to permit access to the interior of the suitcase. A pull strap and a carrying handle are provided. A rigid plastic tray is mounted inside the suitcase and engages the bottom and the sides to provide strength and rigidity to the suitcase.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: October 4, 1994
    Inventor: Fred E. Cohen
  • Synthetic tetrapeptides for the prevention of schistosome parasite infection
    Patent number: 5284829
    Abstract: The invention relates to synthetic tetrapeptides that contain a peptide blocking group at the amino terminus and an enzyme inhibitor at the carboxy terminus, and their use in the prevention of schistosome parasite infection.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: February 8, 1994
    Assignee: The Regents of the University of California
    Inventors: James H. McKerrow, Fred E. Cohen
  • Expandable hand luggage with wheels and separable compartments
    Patent number: 4756394
    Abstract: Expandable luggage which includes a case forming a first compartment and having a hinged cover, and a collapsible bag located at the top of the case and forming a second compartment to provide additional packing space when required. A removable panel is also attached to the top of the case, and the panel forms a pocket for the collapsible bag when the second compartment is not in use.
    Type: Grant
    Filed: November 17, 1986
    Date of Patent: July 12, 1988
    Inventor: Fred E. Cohen