Abstract: The invention relates to a manual cutting tool (110), comprising two arms (112) hinged about an axis (X), each arm comprising a first portion (114) to enable said tool to be grasped by a user and a second cutting portion (116), said first and second portions being separated from one another by said axis, the second portions of the arms comprising cutting edges (118) that define a cross-sectional area (A) of an element to be cut, the tool being configured such that a hinge on the arms about said axis brings the cutting edges of the arms together and cuts said element. The invention is characterized in that it further comprises a member (130) for protecting the user, which is made of a transparent material, said member extending substantially in parallel with said cross-sectional area and covering same completely, and being flexible in a plane substantially perpendicular to said cross-sectional area.

Abstract: The present invention discloses compounds according to Formula I: Wherein R1, R2, R3a, R3b, and Cy are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory conditions, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering a compound of the invention.

Abstract: The present invention discloses compounds according to Formula I: Wherein R1, R2, R3a, R3b, and Cy are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory conditions, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering a compound of the invention.

Abstract: A composite cell plate can include a polymer element laterally mated and interlocked, at a plurality of engagement points, with a resilient metal element. The cell plate can be used in an electrochemical cell. A method of forming a cell plate can include fitting a polymer element to a resilient metal element at a plurality of engagement points, and expanding the polymer of the polymer element such that the polymer element and the resilient metal element engage and interlock at the engagement points.

Abstract: An electron tube includes: a microwave structure having an evacuated envelope including two ends, the microwave structure being at a reference potential, an electron gun including a cathode for providing a beam of electrons, along an axis, at one end of the evacuated envelope, an electron collector for gathering electrons of the beam at the other end of the evacuated envelope, and at least one high-voltage power supply for applying to the cathode a negative high-voltage potential with respect to the reference potential. The tube includes between the cathode and the microwave structure a device for extracting the positive ions including at least one electrode carried to a negative potential with respect to the reference potential so as to extract positive ions from the evacuated envelope, these positive ions being produced by the impacting of the electrons of the electron beam with molecules of residual gas in the evacuated envelope. The invention has application to microwave electron tubes, klystron TWT etc.

Abstract: A cell stack comprising an electrochemical cell, or a plurality of axially arranged electrochemical cells, with an end plate at each end of the stack, each cell comprising an active area surrounded by a peripheral area, wherein the active area comprises the membrane electrode assembly, and the peripheral area includes one or more channels for reactants, and wherein the stack comprises means for applying pressure axially to the active area to contact the membrane and electrodes, and separate means for applying pressure axially to the peripheral area. Further, a method of performing an electrochemical reaction in a cell comprising an active area surrounded by a peripheral area, comprises applying pressure to the active area, and varying the pressure during operation of the cell, wherein the active area includes the membrane electrode assembly and is the area where the cell reaction occurs.

Abstract: An electron tube includes: a microwave structure having an evacuated envelope including two ends, the microwave structure being at a reference potential, an electron gun including a cathode for providing a beam of electrons, along an axis, at one end of the evacuated envelope, an electron collector for gathering electrons of the beam at the other end of the evacuated envelope, and at least one high-voltage power supply for applying to the cathode a negative high-voltage potential with respect to the reference potential. The tube includes between the cathode and the microwave structure a device for extracting the positive ions including at least one electrode carried to a negative potential with respect to the reference potential so as to extract positive ions from the evacuated envelope, these positive ions being produced by the impacting of the electrons of the electron beam with molecules of residual gas in the evacuated envelope. The invention has application to microwave electron tubes, klystron TWT etc.

Abstract: The invention relates to an optically-controlled field-emission cathode, comprising a substrate (10, 20, 30, 40, 50, 60, 70, 80, 90, 100) having at least one conducting surface (11, 21, 31, 41, 51, 61, 71, 81, 91, 101) and at least one conducting emitter element (16, 26, 36, 46, 56, 66, 76, 86, 96, 106) in the vicinity of a conducting surface, characterized in that it also comprises at least one photoconducting element (13, 23, 33, 43, 53, 63, 73, 83, 93, 103) electrically connected in series between at least one emitter element and a conducting surface of the substrate. Another subject of the invention is an amplifier tube comprising such a cathode. The application is for Vacuum tubes, in particular for microwave amplification, with a view for example to applications in telecommunications.

Abstract: The invention relates to an optically-controlled field-emission cathode, comprising a substrate (10, 20, 30, 40, 50, 60, 70, 80, 90, 100) having at least one conducting surface (11, 21, 31, 41, 51, 61, 71, 81, 91, 101) and at least one conducting emitter element (16, 26, 36, 46, 56, 66, 76, 86, 96, 106) in the vicinity of a conducting surface, characterized in that it also comprises at least one photoconducting element (13, 23, 33, 43, 53, 63, 73, 83, 93, 103) electrically connected in series between at least one emitter element and a conducting surface of the substrate. Another subject of the invention is an amplifier tube comprising such a cathode. The application is for Vacuum tubes, in particular for microwave amplification, with a view for example to applications in telecommunications.

Abstract: An industrial control and automation human machine interface (HMI) technology is disclosed that includes a centralized definition of data quality and status behaviors for graphical elements. The centralized definition is thereafter applied to every graphical element that is linked to a data value for which status is maintained/provided. Centrally configured data quality and status indication behaviors are incorporated across entire HMI applications and even sets of HMI applications in a system to inform an operator of the data quality and/or status of read/written data through globally defined data status animation behavior. The centrally defined behaviors are distributed to all nodes on a system and incorporated in live applications without shutting down the applications to update their behavior definition. A status graphic element type. The status graphical element examines a designated data variable and displays a picture or icon indicating the quality or status of the data.

Abstract: The present invention relates to delayed release coated cores comprising an active substance in their core and a polymer coating comprising at least one or more ammonio methacrylate copolymer, characterized in that the core comprises at least a surfactant; to monolithic or multiparticulate pharmaceutical dosage forms comprising such delayed release coated cores and to their method of manufacture.

Abstract: The invention concerns a novel formulation for prolonged release of an active principle having a pH-dependent solubility. The inventive formulation comprises a matrix support based on hydrophilic polymer containing a specific dose of active principle, and further comprises one or more acidifying agents in the form of an acid salt of an organic acid.

Abstract: The present invention relates to timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period, according to a profile of dissolution characterized in that it comprises two release pulses, the first being immediate (lasting up to 30 minutes) and the second being delayed by a fixed time (this fixed time being between 50 and 200 minutes).

Abstract: The invention relates to a solid pharmaceutical composition for oral administration of amisulpride, which comprises at least one coated amisulpride particle and at least one pharmaceutically acceptable excipient suitable for an orodispersible administration of the composition.

Abstract: The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterized in that it comprises two or three layers and contains (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers.

Abstract: Timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period according to a profile of dissolution comprising two release pulses, the first being immediate and the second being delayed by a fixed time after administration.

Abstract: A device for linearizing an RF or microwave signal output to an amplification stage including a traveling wave tube or a solid-state amplifier. A separator including a circulator and of a Schottky diode arrangement matched to the low-amplitude signals creates, for cheaper cost of components, of assemblage and of tuning, a compression path and an expansion path with excellent isolation performance and stability performance. Such a device may find particular application to telecommunications or to radar.

Abstract: The present invention relates to controlled-release dosage forms of zolpidem or salts thereof adapted to release zolpidem over a predetermined time period, according to a biphasic profile of dissolution, where the first phase is an immediate release phase and the second phase is a prolonged release phase and particular embodiments thereof intended to avoid abuse.

Abstract: Method for reducing the effect of the vibration generated by the driveline of a helicopter. The helicopter includes at least one rotor, the collective pitch of the blades of which can be controlled by a control system. The values of at least one parameter representing the effect of the vibration generated by the driveline are measured. A control signal for the collective pitch of the blades of the rotor is directly formed from the measured values of the parameter. The control signal to the system for controlling the collective pitch of the blades of the rotor generates a set of forces and of moments which oppose the effect of the vibration generated by the driveline. The control signal thus formed is applied to the system for controlling the collective pitch of blades of the rotor.

Abstract: An apparatus for adaptable performance evaluation of an application including queries by analytical resolution of a data base, and operating on an information processing system having a given architecture, including a library for knowledge of the specific environment of a data base. The knowledge library, in an environment specification language, includes an architecture library for modeling hardware architectures; a system library modeling the operational and transactional systems supported by the hardware architectures; an access and operation method library modeling the algorithms used by the data management system; and a library of data base profiles collecting knowledge on the data base layout and statistics on the user application. A local optimizer uses a performance evaluator to evaluate the application and select an optimal plan for the execution thereof using the information in the knowledge library including information on the given architecture.