Patents by Inventor Frederick H. Strickler

Frederick H. Strickler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9631042
    Abstract: The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: April 25, 2017
    Assignees: BOSTON SCIENTIFIC SCIMED, INC., THE UNIVERSITY OF MASSACHUSETTS LOWELL
    Inventors: Mark Boden, Marlene C. Schwarz, Frederick H. Strickler, Rudolf Faust, Umaprasana Ojha, Tomoya Higashihara
  • Patent number: 9220811
    Abstract: In various aspects, the present invention is directed to implantable neurostimulation leads and methods for their formation. In various additional aspects, the present invention is directed to medical devices having silicone-containing regions with overlying polymeric layers and to methods of forming the same.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: December 29, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Edward Holman Overstreet, Anne M. Pianca, Janusz A. Kuzman, Aditya Pandit, Shaina Brito, Robert E. Richard, Kerri DiPietro, Frederick H. Strickler, Mark Boden, Lan Pham, William Orinski
  • Publication number: 20150203622
    Abstract: The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.
    Type: Application
    Filed: November 12, 2014
    Publication date: July 23, 2015
    Inventors: Mark Boden, Marlene C. Schwarz, Frederick H. Strickler, Rudolf Faust, Umaprasana Ojha, Tomoya Higashihara
  • Patent number: 8911760
    Abstract: The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: December 16, 2014
    Assignees: Boston Scientific Scimed, Inc., The University of Massachusetts Lowell
    Inventors: Mark Boden, Marlene C. Schwarz, Frederick H. Strickler, Rudolf Faust, Umaprasana Ojha, Tomoya Higashihara
  • Patent number: 8870814
    Abstract: Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region, which controls the release of the therapeutic agent upon administration to a patient. The polymeric release region further comprises a silicone copolymer that contains a plurality of siloxane units and a plurality of non-siloxane units. Also described are methods for administering a therapeutic agent to a patient using the above implantable or insertable medical devices as well as methods of making the above devices.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: October 28, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Robert E. Richard, Marlene C. Schwarz, Frederick H. Strickler
  • Patent number: 8535702
    Abstract: The present invention relates to phase separated polymeric regions and to their use in conjunction with implantable or insertable medical devices. In some aspects of the invention, phase separated polymeric regions are provided that include (a) at least one biostable polymeric phase and (b) at least one biodisintegrable polymeric phase, which is of nanoscale dimensions and which undergoes biodisintegration such that the phase separated polymeric region becomes a nanoporous polymeric region in vivo. Other aspects of the invention are directed to methods of making implantable or insertable medical devices having at least one nanoporous polymeric region. These methods include (a) providing a phase separated polymeric region comprising a stable polymeric phase and a disintegrable polymeric phase of nanoscale dimensions, (b) selectively removing the disintegrable polymeric phase thereby producing the nanoporous polymeric region.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: September 17, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Robert E. Richard, Frederick H. Strickler, Marlene C. Schwarz, Rudolf Faust, Shrirang V. Ranade, Michael N. Helmus
  • Patent number: 8501831
    Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 6, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Shrojalkumar Desai, Marlene C. Schwarz, Mark Boden, Mohan Krishnan, Michael C. Smith, Frederick H. Strickler, Daniel J. Cooke
  • Publication number: 20130013040
    Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Inventors: Shrojalkumar Desai, Marlene C. Schwarz, Mark Boden, Mohan Krishnan, Michael C. Smith, Frederick H. Strickler, Daniel J. Cooke
  • Patent number: 8324290
    Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: December 4, 2012
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Shrojalkumar Desai, Marlene C. Schwarz, Mark Boden, Mohan Krishnan, Michael C. Smith, Frederick H. Strickler, Daniel J. Cooke
  • Patent number: 8092821
    Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain at least one polymeric region in contact with a metallic region. The polymeric region contains at least one block copolymer that contains at least one low Tg block and at least one high Tg block. The polymeric region contains at least one polymer that contains at least one adhesion promoting group selected from one or more of halo-silane, alkoxy-silane, epoxy, anhydride, phenoxy, hydroxyl, amino, sulfonate and carboxyl groups, which at least one polymer may correspond to the block copolymer, a supplemental polymer, or both.
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: January 10, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Frederick H. Strickler
  • Patent number: 8034874
    Abstract: In one aspect, the present invention provides implantable or insertable medical devices, which contain at least one polymeric region. The polymeric region contains at least one fluorocarbon-containing block copolymer, which, in turn, contains (a) at least one fluorocarbon-containing, low glass transition temperature (low Tg) copolymer chain and (b) at least one glass transition temperature (high Tg) polymer chain.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: October 11, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frederick H. Strickler, Ronald A. Sahatjian
  • Publication number: 20110150972
    Abstract: According to an aspect of the present invention, medical devices are provided that contain at least one polymeric region which contains (a) at least one block copolymer that contains at least at least three polymer blocks that differ from one another and (b) at least one therapeutic agent.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 23, 2011
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Frederick H. Strickler, Shrirang V. Ranade
  • Publication number: 20110144276
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Application
    Filed: February 24, 2011
    Publication date: June 16, 2011
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick H. Strickler
  • Patent number: 7931932
    Abstract: A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in the presence of monomer; (b) contacting the reactive species with at least one monomer species, thereby forming a polymer coating on the surface of the medical device; and (c) providing at least one therapeutic agent within the polymer coating. The therapeutic agent may be incorporated during formation of the polymer coating or after formation of the polymer coating. The at least one reactive species can comprise, for example, a free radical species, a carbanion species, a carbocation species, a Ziegler-Natta polymerization complex, a metallocene complex, and/or an atom transfer radical polymerization initiator.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: April 26, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Robert A. Herrmann, Frederick H. Strickler, Wendy Naimark, Peter L. Dayton
  • Patent number: 7914806
    Abstract: According to an aspect of the present invention, medical devices are provided that contain at least one polymeric region which contains (a) at least one block copolymer that contains at least at least three polymer blocks that differ from one another and (b) at least one therapeutic agent.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: March 29, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frederick H. Strickler, Shrirang V. Ranade
  • Patent number: 7914807
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: March 29, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick H. Strickler
  • Patent number: 7897170
    Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided that contain at least one covalently crosslinked polymeric region, which contains at least one block copolymer comprising at least one low Tg block and at least one high Tg block.
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: March 1, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frederick H. Strickler, Mark Boden
  • Patent number: 7897171
    Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided that contain at least one covalently crosslinked polymeric region, which contains at least one block copolymer comprising at least one low Tg block and at least one high Tg block.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: March 1, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frederick H. Strickler, Mark Boden
  • Patent number: 7887830
    Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain one or more polymeric regions. These polymeric regions, in turn, contain one or more polymers, at least one of which is a copolymer that includes a styrene monomer and an isobutylene monomer. Moreover, the styrene monomer content of the copolymer typically ranges from 25 to 50 mol %.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: February 15, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Jeffrey S. Lindquist, Frederick H. Strickler, Mark Boden, Jan Seppala, Paul J. Miller
  • Patent number: D841809
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: February 26, 2019
    Assignee: C.R. Bard, Inc.
    Inventors: Christopher W. Gelinas, Stephen N. Eldridge, Jon I. Montcrieff, Sarah B. Borysenko, Frederick H. Strickler, Jr., Scott Narkevicius