Patents by Inventor Frederick H. Strickler
Frederick H. Strickler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110150972Abstract: According to an aspect of the present invention, medical devices are provided that contain at least one polymeric region which contains (a) at least one block copolymer that contains at least at least three polymer blocks that differ from one another and (b) at least one therapeutic agent.Type: ApplicationFiled: February 28, 2011Publication date: June 23, 2011Applicant: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Shrirang V. Ranade
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Publication number: 20110144276Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: ApplicationFiled: February 24, 2011Publication date: June 16, 2011Applicant: Boston Scientific Scimed, Inc.Inventors: Shaina Brito, Frederick H. Strickler
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Patent number: 7931932Abstract: A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in the presence of monomer; (b) contacting the reactive species with at least one monomer species, thereby forming a polymer coating on the surface of the medical device; and (c) providing at least one therapeutic agent within the polymer coating. The therapeutic agent may be incorporated during formation of the polymer coating or after formation of the polymer coating. The at least one reactive species can comprise, for example, a free radical species, a carbanion species, a carbocation species, a Ziegler-Natta polymerization complex, a metallocene complex, and/or an atom transfer radical polymerization initiator.Type: GrantFiled: February 14, 2008Date of Patent: April 26, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Robert A. Herrmann, Frederick H. Strickler, Wendy Naimark, Peter L. Dayton
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Patent number: 7914807Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: GrantFiled: March 5, 2007Date of Patent: March 29, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Shaina Brito, Frederick H. Strickler
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Patent number: 7914806Abstract: According to an aspect of the present invention, medical devices are provided that contain at least one polymeric region which contains (a) at least one block copolymer that contains at least at least three polymer blocks that differ from one another and (b) at least one therapeutic agent.Type: GrantFiled: June 1, 2006Date of Patent: March 29, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Shrirang V. Ranade
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Patent number: 7897170Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided that contain at least one covalently crosslinked polymeric region, which contains at least one block copolymer comprising at least one low Tg block and at least one high Tg block.Type: GrantFiled: June 1, 2007Date of Patent: March 1, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Mark Boden
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Patent number: 7897171Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided that contain at least one covalently crosslinked polymeric region, which contains at least one block copolymer comprising at least one low Tg block and at least one high Tg block.Type: GrantFiled: February 27, 2009Date of Patent: March 1, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Mark Boden
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Patent number: 7887830Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain one or more polymeric regions. These polymeric regions, in turn, contain one or more polymers, at least one of which is a copolymer that includes a styrene monomer and an isobutylene monomer. Moreover, the styrene monomer content of the copolymer typically ranges from 25 to 50 mol %.Type: GrantFiled: February 21, 2008Date of Patent: February 15, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Jeffrey S. Lindquist, Frederick H. Strickler, Mark Boden, Jan Seppala, Paul J. Miller
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Publication number: 20100256720Abstract: In various aspects, the present invention is directed to implantable neurostimulation leads and methods for their formation. In various additional aspects, the present invention is directed to medical devices having silicone-containing regions with overlying polymeric layers and to methods of forming the same.Type: ApplicationFiled: September 21, 2009Publication date: October 7, 2010Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATIONInventors: Edward Holman Overstreet, Anne M. Pianca, Janusz A. Kuzma, Aditya Pandit, Shaina G. Brito, Robert E. Richard, Kerri DiPietro, Frederick H. Strickler, Mark Boden, Lan Pham, William Orinski
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Patent number: 7771740Abstract: The present invention provides a medical device comprising a release region and a therapeutic agent disposed within or beneath the release region, and the release region includes a copolymer comprising a low Tg block and at least one graft copolymer endblock having a main chain and a plurality of side chains.Type: GrantFiled: July 19, 2004Date of Patent: August 10, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Robert E. Richard
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Publication number: 20100166820Abstract: The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.Type: ApplicationFiled: December 30, 2009Publication date: July 1, 2010Applicants: BOSTON SCIENTIFIC SCIMED, INC., UNIVERSITY OF MASSACHUSETTS LOWELLInventors: Mark Boden, Marlene C. Schwarz, Frederick H. Strickler, Rudolf Faust, Umaprasana Ojha, Tomoya Higashihara
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Patent number: 7737060Abstract: According to an aspect of the present invention, medical devices are provided that contain at least one multi-component polymeric fiber. The multi-component polymeric fiber further contains at least two components of differing composition.Type: GrantFiled: March 31, 2006Date of Patent: June 15, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Barron Tenney
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Patent number: 7713539Abstract: The present invention relates generally to radiation-resistant medical devices which contain polymer regions for release of therapeutic agents. The present invention also relates to radiation-resistant block copolymer materials for use in connection with insertable or implantable medical devices. The radiation-sterilized medical device comprise (a) a release region and (b) at least one therapeutic agent and the release region comprises a radiation resistant copolymer that includes (i) a low Tg hydrocarbon polymer block and (ii) one or more high Tg polymer blocks.Type: GrantFiled: July 19, 2004Date of Patent: May 11, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Robert E. Richard
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Publication number: 20100023104Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.Type: ApplicationFiled: June 26, 2009Publication date: January 28, 2010Applicant: Cardiac Pacemakers, Inc.Inventors: Shrojalkumar Desai, Marlene C. Schwarz, Mark Boden, Mohan Krishnan, Michael C. Smith, Frederick H. Strickler, Daniel J. Cooke
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Publication number: 20090326077Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.Type: ApplicationFiled: June 26, 2009Publication date: December 31, 2009Applicant: Cardiac Pacemakers, Inc.Inventors: Shrojalkumar Desai, Marlene C. Schwarz, Mark Boden, Mohan Krishnan, Michael C. Smith, Frederick H. Strickler, Daniel J. Cooke
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Publication number: 20090186067Abstract: According to an aspect of the present invention, implantable or insertable medical devices are provided that contain at least one covalently crosslinked polymeric region, which contains at least one block copolymer comprising at least one low Tg block and at least one high Tg block.Type: ApplicationFiled: February 27, 2009Publication date: July 23, 2009Applicant: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Mark Boden
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Publication number: 20090156772Abstract: In accordance with an aspect of the invention, methods of forming medical articles are provided, which comprise (a) preparing a melt phase that comprises a molten polymer and a supercritical fluid, (b) forming a polymeric region from the melt phase, and (c) cooling the polymeric region. In certain embodiments, the supercritical fluid is formed from chemical species (e.g., CO2, propane, etc.) that are gases at room temperature (25° C.) and atmospheric pressure (1 atm). According to another aspect of the present invention, medical articles are provided which comprise melt-processed polymeric materials. The polymeric materials have a composition that cannot be melt processed without the use of melt-viscosity reducing additives due to thermal degradation, and yet the polymeric material does not contain such additives.Type: ApplicationFiled: December 12, 2007Publication date: June 18, 2009Applicant: Boston Scientific Scimed, Inc.Inventors: Frederick H. Strickler, Barron Tenney, Mark Boden
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Publication number: 20090104244Abstract: A medical device comprising: (a) a substrate having first and second surfaces, (b) a therapeutic-agent-eluting polymeric layer disposed over the first substrate surface and (c) a textured polymeric layer that is textured to promote cell attachment, cell growth, or both, disposed over the second surface.Type: ApplicationFiled: September 19, 2008Publication date: April 23, 2009Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Aiden Flanagan, Mark Boden, Frederick H. Strickler, Barron W. Tenney
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Publication number: 20080220041Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: ApplicationFiled: March 5, 2007Publication date: September 11, 2008Inventors: Shaina Brito, Frederick H. Strickler
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Publication number: 20080208325Abstract: According to an aspect of the present invention, long term medical articles are provided which include the following: (a) first and second body contacting (e.g., tissue and/or body-fluid contacting) porous polymeric layers; (b) a polymeric barrier layer disposed between the first and second porous polymer layers; and (c) a reinforcement element. According to another aspect of the present invention, tubular medical articles for long term implantation are provided, which comprise: (a) a reinforcement element; (b) a blood contacting porous polymeric layer having a surface energy ranging between 20 and 30 dynes/cm disposed over an inner surface of the reinforcement element; and (c) an additional porous polymeric layer formed over an outer surface of the reinforcement element.Type: ApplicationFiled: February 25, 2008Publication date: August 28, 2008Applicant: Boston Scientific Scimed, Inc.Inventors: Michael N. Helmus, Barron Tenney, Yixin Xu, Kevin M. Alves, Frederick H. Strickler, Kathleen M. Miller, Mark Boden