Patents by Inventor Fredrik Oberg

Fredrik Oberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10336780
    Abstract: The invention provides compounds of the formula: R1 is OR11, or NR5R5?; R2 is H or F; R5 is H, C1-C6alkyl, OH, C(?O)R6, O(C?O)R6 or O(C?O)OR6; R5 is H or C1-C6alkyl; R6 is C1-C6alkyl or C3-C7cycloalkyl; R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2 or 3 R22; and the other variables are as defined in the claims, which are of use in the treatment of cancer, and related aspects.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: July 2, 2019
    Assignee: MEDIVIR AB
    Inventors: Richard Bethell, Anders Eneroth, Bjorn Klasson, Fredrik Oberg
  • Publication number: 20190100541
    Abstract: The invention provides compounds of the formula: R1 is OR11, or NR5R5?; R2 is H or F; R5 is H, C1-C6alkyl, OH, C(?O)R6, O(C?O)R6 or O(OQ)OR6; R5? is H or C1-C6alkyl; R6 is C1-C6alkyl or C3-C7cloalkyl; R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2 or 3 R22; and the other variables are as defined in the claims, which are of use in the treatment of cancer, and related aspects.
    Type: Application
    Filed: December 3, 2018
    Publication date: April 4, 2019
    Inventors: Richard BETHELL, Anders ENEROTH, Bjorn KLASSON, Fredrik OBERG
  • Publication number: 20190091246
    Abstract: Combination therapy with sorafenib or regorafenib and a phosphoramidate prodrug of troxacitabine with the formula: where Y is C1-C8 straight or branched chain alkyl, X is H, halo, C3-C4cycloalkyl or C1-C4alkyl and Z is H or fluoro, or a pharmaceutically acceptable salt thereof, shows surprising utility in the treatment of liver cancer or liver metastasis.
    Type: Application
    Filed: February 28, 2017
    Publication date: March 28, 2019
    Applicant: Medivir Aktiebolag
    Inventors: Mark ALBERTELLA, Anders ENEROTH, Björn KLASSON, Fredrik ÖBERG, John ÖHD
  • Patent number: 10144750
    Abstract: The invention provides compounds of the formula: R1 is OR11, or NR5R5?; R2 is H or F; R5 is H, OH, C1-C6 alkyl, OH, C(?O)R6, O(C?O)R6 or O(C?O)OR6; R5? is H or C1-C6 alkyl; R6 is C1-C6 alkyl or C3-C7 cycloalkyl; R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2 or 3 R22; and the other variables are as defined in the claims, which are of use in the treatment of cancer, and related aspects.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: December 4, 2018
    Assignee: MEDIVIR AB
    Inventors: Richard Bethell, Anders Eneroth, Bjorn Klasson, Fredrik Oberg
  • Patent number: 9868966
    Abstract: A genetically modified Saccharomyces cerevisiae including an active fermentation pathway producing 3-HP expresses an exogenous gene expressing the aminotransferase YhxA from Bacillus cereus AH1272 catalyzing a transamination reaction between beta-alanine and pyruvate to produce malonate semialdehyde. The yeast may also express a 3-hydroxyisobutyrate dehydrogenase (HIBADH) and a 3-hydroxypropanoate dehydrogenase (3-HPDH) and aspartate 1-decarboxylase. Additionally the yeast may express pyruvate carboxylase and aspartate aminotransferase.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: January 16, 2018
    Assignee: TECHNICAL UNIVERSITY OF DENMARK
    Inventors: Irina Borodina, Kanchana Rueksomtawin Kildegaard, Jochen Förster, Fredrik Öberg
  • Publication number: 20170267705
    Abstract: The invention provides compounds of the formula: R1 is OR11, or NR5R5?; R2 is H or F; R5 is H, OH, C1-C6 alkyl, OH, C(?O)R6, O(C?O)R6 or O(C?O)OR6; R5? is H or C1-C6 alkyl; R6 is C1-C6 alkyl or C3-C7 cycloalkyl; R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2 or 3 R22; and the other variables are as defined in the claims, which are of use in the treatment of cancer, and related aspects.
    Type: Application
    Filed: August 24, 2015
    Publication date: September 21, 2017
    Inventors: Richard BETHEL, Anders ENEROTH, Bjorn KLASSON, Fredrik OBERG
  • Publication number: 20150267228
    Abstract: A genetically modified Saccharomyces cerevisiae including an active fermentation pathway producing 3-HP expresses an exogenous gene expressing the aminotransferase YhxA from Bacillus cereus AH1272 catalysing a transamination reaction between beta-alanine and pyruvate to produce malonate semialdehyde. The yeast may also express a 3-hydroxyisobutyrate dehydrogenase (HIBADH) and a 3-hydroxypropanoate dehydrogenase (3-HPDH) and aspartate 1-decarboxylase. Additionally the yeast may express pyruvate carboxylase and aspartate aminotransferase.
    Type: Application
    Filed: October 10, 2013
    Publication date: September 24, 2015
    Applicant: TECHNICAL UNIVERSITY OF DENMARK
    Inventors: Irina Borodina, Kanchana Rueksomtawin Kildegaard, Jochen Förster, Fredrik Öberg
  • Patent number: 8606542
    Abstract: A system for monitoring and documenting the installation of at least one rock reinforcement bolt in a tunnel or a mine, wherein bolt installation related information is stored and related to the identity of the bolt is distinguished by means (S1, S2, S3, 4) for registering of at least one bolt installation related parameter and means for storing the corresponding installation parameter data in a related memory (M), and means (S4, 4) for registering the installation position and means for storing the corresponding installation position data in a related memory (M). The invention also concerns a method.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: December 10, 2013
    Assignee: Atlas Copco Rock Drills AB
    Inventor: Fredrik Öberg
  • Patent number: 7841803
    Abstract: A device for rock bolting with an adapter device (10) for connection of a drilling machine (3) to a self drilling rock bolt (7), in which the adapter device has an adapter element (14) which is sealingly surrounded by a swivel sleeve (13) for connection to one or more external source for flushing medium (8) and bolt grouting medium (9), and in which the adapter element has a thread for connecting to a corresponding thread on the rock bolt (7), and an integral connection portion for connection to the drilling machine (3).
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: November 30, 2010
    Assignee: Atlas Copco Rock Drills AB
    Inventors: Fredrik Öberg, Per Jonson
  • Patent number: 7811031
    Abstract: A device (5) for installing a pressure fluid expandable rock bolt (4) of the kind having a tubular expansion portion and a fitting portion, said device at a distal portion having chuck means for gripping the fitting portion and for establishing a sealed connection between a fluid source and the inlet, said device extending essentially in an axial direction. The device includes at a proximal portion a holder portion (11) that is adapted to be fitted to a drill string engagement element (27) of a rock drilling machine. The invention also concerns a method and a rig.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: October 12, 2010
    Assignee: Atlas Copco Rock Drills AB
    Inventor: Fredrik Öberg
  • Publication number: 20090016823
    Abstract: A device (5) for installing a pressure fluid expandable rock bolt (4) of the kind having a tubular expansion portion and a fitting portion, said device at a distal portion having chuck means for gripping the fitting portion and for establishing a sealed connection between a fluid source and the inlet, said device extending essentially in an axial direction. The device includes at a proximal portion a holder portion (11) that is adapted to be fitted to a drill string engagement element (27) of a rock drilling machine. The invention also concerns a method and a rig.
    Type: Application
    Filed: March 24, 2006
    Publication date: January 15, 2009
    Inventor: Fredrik Oberg
  • Patent number: 7377724
    Abstract: In a method and a device for installing, in a rock wall or roof, a self-drilling expandable rock bolt (2) having a drill bit portion (5), an expansion portion (9) and a connecting portion (10), in a rock breaking step, the self-drilling rock bolt (2) is provided with a rock breaking movement and flushing fluid for producing a bore hole, and in an expansion step, pressurized expansion fluid is introduced into the expansion portion (9) in order to expand it so as to be fixed to the inside of the bore hole. Expansion fluid is introduced by means of a swiveling device (6) so that the rock bolt (2) is free to move during the rock breaking step, and be tightened against the rock bolt (2) in the expansion step in such a way that a sealed channel for expansion fluid is established between an expansion fluid source and the expansion portion (9). The invention also concerns a self-drilling rock bolt.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: May 27, 2008
    Assignee: Atlas Copco Rock Drills AB
    Inventors: Fredrik Öberg, Morgan Kanflod
  • Publication number: 20080085161
    Abstract: A system for monitoring and documenting the installation of at least one rock reinforcement bolt in a tunnel or a mine, wherein bolt installation related information is stored and related to the identity of the bolt is distinguished by means (S1, S2, S3, 4) for registering of at least one bolt installation related parameter and means for storing the corresponding installation parameter data in a related memory (M), and means (S4, 4) for registering the installation position and means for storing the corresponding installation position data in a related memory (M). The invention also concerns a method.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 10, 2008
    Inventor: Fredrik Oberg
  • Patent number: 7320560
    Abstract: The present invention is related to a method for manual installation of rock bolts expandable by means of a pressure media comprising manual coupling of a pressure source to a rock bolt to be expanded. The method comprises the steps of an operator starting a sequence whereby the rock bolt is pressurized to a predetermined pressure, and it being ensured that the predetermined pressure is kept for a predetermined period of time. The present invention is also related to such a control system, and an apparatus comprising such a control system.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: January 22, 2008
    Assignee: Atlas Copco Rock Drills AB
    Inventors: Tommy Persson, Morgan Kanflod, Fredrik Öberg, Tapio Toivonen, Niclas Örjas, Hans Gustavsson, Göran Sjöstedt
  • Patent number: 7318689
    Abstract: Method and device for rock bolting, wherein a tubular bolt (2) with closed cross-section is inserted and expanded for anchoring inside a bore hole (12), wherein the tubular bolt is expanded to contact in the inner portion of the bore hole, a tension element (3, 7, 8, 9) which is arranged in the outer portion of the bore hole with an inner part (7) attached to the tubular bolt (2) is pre-stressed and a settable medium is injected into the outer portion of the bore hole (14) between (27) the tension element and the wall of the bore hole and is allowed to set.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: January 15, 2008
    Assignee: Atlas Copco Rock Drills AB
    Inventors: Morgan Kanflod, Fredrik Öberg
  • Publication number: 20070253783
    Abstract: A method for providing a rock bolt (2) for rock bolting, wherein a rock bolt (2) having a tubular bolt portion (4) with a closed cross section is inserted and expanded for bearing contact in a bore hole (3) in a rock structure (1). The length of the tubular bolt portion (4) is determined such that maximum frictional force at pulling inside a bore hole (3) of a rock bolt with a tubular bolt portion with this length is below a predetermined maximum value. The invention also concerns a rock bolt.
    Type: Application
    Filed: April 18, 2005
    Publication date: November 1, 2007
    Inventors: Mario Bureau, Fredrik Oberg, Francois Charette
  • Patent number: 7270501
    Abstract: The present invention is related to a rock bolt (7), expandable by means of a pressure media, for insertion into a borehole. The expandable bolt (7) comprises a connection unit (8) with means (11) for detachable interaction with an expansion means (10) for expansion of the rock bolt (7), as well as with a suspension element (16). The connection unit is designed with such external dimensions so that it may be inserted into the bore-hole. The invention also relates to such a rock bolting system.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: September 18, 2007
    Assignee: Atlas Copco Rock Drills AB
    Inventors: Morgan Kanflod, Fredrik Öberg
  • Publication number: 20070122238
    Abstract: In a method and a device for installing, in a rock wall or roof, a self-drilling expandable rock bolt (2) having a drill bit portion (5), an expansion portion (9) and a connecting portion (10), in a rock breaking step, the self-drilling rock bolt (2) is provided with a rock breaking movement and flushing fluid for producing a bore hole, and in an expansion step, pressurized expansion fluid is introduced into the expansion portion (9) in order to expand it so as to be fixed to the inside of the bore hole. Expansion fluid is introduced by means of a swiveling device (6) so that the rock bolt (2) is free to move during the rock breaking step, and be tightened against the rock bolt (2) in the expansion step in such a way that a sealed channel for expansion fluid is established between an expansion fluid source and the expansion portion (9). The invention also concerns a self-drilling rock bolt.
    Type: Application
    Filed: October 20, 2004
    Publication date: May 31, 2007
    Inventors: Fredrik Oberg, Morgan Kanflod
  • Publication number: 20070036614
    Abstract: The present invention is related to a method for manual installation of rock bolts expandable by means of a pressure media comprising manual coupling of a pressure source to a rock bolt to be expanded. The method comprises the steps of an operator starting a sequence whereby the rock bolt is pressurized to a predetermined pressure, and it being ensured that the predetermined pressure is kept for a predetermined period of time. The present invention is also related to such a control system, and an apparatus comprising such a control system.
    Type: Application
    Filed: May 12, 2004
    Publication date: February 15, 2007
    Applicant: ATLAS COPCO ROCK DRILLS AB
    Inventors: Tommy Persson, Morgan Kanflod, Tapio Toivonen, Fredrik Öberg, Niclas Örjas, Hans Gustavsson, Göran Sjöstedt
  • Publication number: 20060285928
    Abstract: The present invention is related to a rock bolt (7), expandable by means of a pressure media, for insertion into a borehole. The expandable bolt (7) comprises a connection unit (8) with means (11) for detachable interaction with an expansion means (10) for expansion of the rock bolt (7), as well as with a suspension element (16). The connection unit is designed with such external dimensions so that it may be inserted into the bore-hole. The invention also relates to such a rock bolting system.
    Type: Application
    Filed: May 12, 2004
    Publication date: December 21, 2006
    Inventors: Morgan Kanflod, Fredrik Oberg