Patents by Inventor Fujian Qu

Fujian Qu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240207600
    Abstract: Circulatory support systems and related methods are disclosed in which a ventricular assist device is controlled based on cardiac activity monitored via cardiogram electrodes. A circulatory support system includes a ventricular assist device, cardiogram electrodes, and a controller. The controller processes a cardiogram signal generated via the cardiogram electrodes to determine one or more physiological parameters indicative of an activity level and/or cardiac cycle timing, determines at least one operating parameter for the ventricular assist device based on the one or more physiological parameters, and controls operation of the ventricular assist device in accordance with the at least one operating parameter.
    Type: Application
    Filed: December 23, 2022
    Publication date: June 27, 2024
    Applicant: TC1 LLC
    Inventors: Daniel I. Harjes, Brian Kimball, Pritika Toutam, Fujian Qu
  • Publication number: 20240189603
    Abstract: Methods, devices, and program products are provided under control of one or more processors within an implantable medical device (IMD) that senses far field (FF) signals between a combination of electrodes coupled to the IMD. Correlation scores are determined by comparing the FF signals associated with a number of beats to a template. The correlation scores of the number of beats are compared to a correlation threshold, and correlation variability scores are determined for the number of beats. Shock delivery, by a pulse generator within the IMD, is postponed in response to i) a first number of beats within the number of beats having the correlation scores that are less than the correlation threshold, and ii) a second number of beats within the number of beats having correlation variability scores that are less than a correlation variability threshold.
    Type: Application
    Filed: November 30, 2023
    Publication date: June 13, 2024
    Inventors: Fady Dawoud, Fujian Qu, Wenwen Li, Mark Sprowls, Laukik Nagawekar, Jennifer Lecocq Rhude, Kevin J. Davis, Luke C. McSpadden
  • Patent number: 11998746
    Abstract: System and methods are provided for determining a stimulation threshold for closed loop spinal cord stimulation (SCS). The system and methods provide a lead coupled to an implantable pulse generator (IPG). The system and methods deliver SCS pulses from the IPG to the lead electrodes in accordance with an SCS therapy and determine an evoked compound action potential (ECAP) amplitude based on an ECAP waveform resulting from the SCS therapy. The system and methods increase the SCS therapy by increasing at least one of an amplitude, a duration, and number of the SCS pulses associated with the SCS therapy. The system and methods also include iteratively repeat the delivering, determining and increasing operations until the ECAP amplitude exhibits a downward trend divergence. The system and methods define a stimulation threshold based on the ECAP amplitude at the trend divergence.
    Type: Grant
    Filed: August 24, 2021
    Date of Patent: June 4, 2024
    Assignee: Pacesetter, Inc.
    Inventors: Wenbo Hou, Fujian Qu, Stuart Rosenberg, Kyungmoo Ryu
  • Publication number: 20240156387
    Abstract: Systems and methods described herein improve visibility of features (e.g., P-waves) of a physiologic signal segment (e.g., an EGM or ECG signal segment) to be displayed within a display band having a specified height between an upper and a lower boundary of the display band. The physiologic signal segment is divided into sub-segments, for each of which a sub-segment minimum peak amplitude and maximum peak amplitude are determined. Based thereon, a new minimum peak amplitude and a new maximum peak amplitude are determined and used to determine a new display range. A portion of the physiologic signal segment that is within the new display range is caused to be display, within the display band having the specified height, such that the upper boundary of the display band corresponds to the new maximum peak amplitude, and the lower boundary of the display band corresponds to the new minimum peak amplitude.
    Type: Application
    Filed: September 5, 2023
    Publication date: May 16, 2024
    Applicant: Pacesetter, Inc.
    Inventors: Fujian Qu, Praveen Gopalakrishna, Tejpal Singh
  • Publication number: 20240156388
    Abstract: Systems and methods described herein improve visibility of P-waves of an EGM or ECG signal segment to be displayed on a display screen. There is a determination of whether relatively small features, including the P-waves, of the ECG or EGM signal segment would be difficult to visualize if an original signal segment range of the ECG or EGM signal segment were caused to be displayed on the display screen. In response to determining that the relatively small features of the ECG or EGM signal segment would be difficult to visualize, a portion of the EGM or ECG signal segment is displayed on the display screen in a manner that magnifies the P-waves of the EGM or ECG signal segment compared to if an entirety of the EGM or ECG signal segment within the original signal segment range were instead caused to be displayed on the display screen.
    Type: Application
    Filed: October 19, 2023
    Publication date: May 16, 2024
    Applicant: Pacesetter, Inc.
    Inventors: Fujian Qu, Praveen Gopalakrishna, Tejpal Singh
  • Publication number: 20240099641
    Abstract: A computer implemented method for detecting arrhythmias in cardiac activity including obtaining far field cardiac activity (CA) signals for a series of beats. For at least a portion of the beats, the one or more processors perform, on a beat by beat basis: a) identifying first and second feature of interests (FOI) from a segment of the CA signal that corresponds to a current beat; and b) classifying the current beat into one of first and second groups. The method also includes designating one of the first and second groups to be a primary group based on a relation between the first and second groups, and for the beats in the primary group, selecting one of the first and second FOIs as the R-wave FOI. The method also includes rejecting an arrhythmia detection based on the P-waves detected.
    Type: Application
    Filed: December 6, 2023
    Publication date: March 28, 2024
    Inventors: Fujian Qu, Nima Badie, Jong Gill
  • Publication number: 20240074706
    Abstract: Computer implemented methods and systems for detecting noise in cardiac activity are provided. The method and system obtain a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats, overlay a segment of the CA signals with a noise search window, and identify turns in the segment of the CA signals. The method and system determine whether the turns exhibit a turn characteristic that exceed a turn characteristic threshold, declare the segment of the CA signals as a noise segment based on the determining operation, shift the noise search window to a next segment of the CA signal and repeat the identifying, determining and declaring operations; and modify the CA signals based on the declaring the noise segments.
    Type: Application
    Filed: November 6, 2023
    Publication date: March 7, 2024
    Inventors: Jong Gill, Fujian Qu, Neha Malhotra, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud
  • Patent number: 11883178
    Abstract: A computer implemented method for detecting arrhythmias in cardiac activity including obtaining far field cardiac activity (CA) signals for a series of beats. For at least a portion of the beats, the one or more processors perform, on a beat by beat basis: a) identifying first and second feature of interests (FOI) from a segment of the CA signal that corresponds to a current beat; and b) classifying the current beat into one of first and second groups. The method also includes designating one of the first and second groups to be a primary group based on a relation between the first and second groups, and for the beats in the primary group, selecting one of the first and second FOIs as the R-wave FOI. The method also includes rejecting an arrhythmia detection based on the P-waves detected.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: January 30, 2024
    Assignee: Pacesetter, Inc.
    Inventors: Fujian Qu, Nima Badie, Jong Gill
  • Patent number: 11844630
    Abstract: Computer implemented methods and systems for detecting noise in cardiac activity are provided. The method and system obtain a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats, overlay a segment of the CA signals with a noise search window, and identify turns in the segment of the CA signals. The method and system determine whether the turns exhibit a turn characteristic that exceed a turn characteristic threshold, declare the segment of the CA signals as a noise segment based on the determining operation, shift the noise search window to a next segment of the CA signal and repeat the identifying, determining and declaring operations; and modify the CA signals based on the declaring the noise segments.
    Type: Grant
    Filed: December 20, 2022
    Date of Patent: December 19, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Fujian Qu, Neha Malhotra, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud
  • Patent number: 11793445
    Abstract: Methods and systems are provided for detecting arrhythmias in cardiac activity. The methods and systems declare a current beat, from the CA signals, to be a candidate beat or an ineligible beat based on whether the current beat satisfies the rate based selection criteria. The determining and declaring operations are repeated for multiple beats to form an ensemble of candidate beats. The method and system calculate a P-wave segment ensemble from the ensemble of candidate beats, perform a morphology-based comparison between the P-wave segment ensemble and at least one of a monophasic or biphasic template, declare a valid P-wave to be present within the CA signals based on the morphology-based comparison, and utilize the valid P-wave in an arrhythmia detection process to determine at least one of an arrhythmia entry, arrhythmia presence or arrhythmia exit.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: October 24, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Neha Malhotra, Fujian Qu, Jong Gill, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud
  • Patent number: 11766207
    Abstract: Described herein are methods, devices, and systems for improving R-wave detection sensitivity and positive predictive value, and for improving arrhythmia detection accuracy. Certain embodiments involve determining whether to classify a potential R-wave as a false R-wave (or more specifically, an over-sensed P-wave) by determining a measure of magnitude of a first portion of the signal corresponding to a first window following the potential R-wave, determining the measure of magnitude of a second portion of the signal corresponding to a second window following the first window, and classifying the potential R-wave as a false R-wave if the measure of magnitude of the second portion of the signal is at least a specified extent larger (e.g., at least 3 times larger) than the measure of magnitude of the first portion of the signal. Certain embodiments also involve adjusting an R-wave marker for a potential R-wave that is classified as a false R-wave.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: September 26, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Nima Badie, Fujian Qu, Jong Gill
  • Publication number: 20230293085
    Abstract: Described herein are apparatuses and methods to detect tachycardias and selectively reject false tachycardia detections due to T-wave oversensing or noise. An apparatus includes electrodes, a sensing circuit coupled to at least two of the electrodes and configured to sense a signal indicative of cardiac electrical activity, and a smoothing filter configured to filter to the sensed signal indicative of cardiac electrical activity to thereby produce a filtered signal indicative of cardiac electrical activity. The apparatus produces a difference signal indicative of cardiac electrical activity by determining a difference between the sensed and filtered signals indicative of cardiac electrical activity. The apparatus also includes at least one processor configured to detect a tachycardia, or to determine whether or not to reject a tachycardia detection, based on the difference signal. The smoothing filter and/or difference circuitry can be implemented by the at least one processor, and/or other circuitry.
    Type: Application
    Filed: February 3, 2023
    Publication date: September 21, 2023
    Applicant: Pacesetter, Inc.
    Inventor: Fujian Qu
  • Publication number: 20230293083
    Abstract: Described herein are methods, devices, and systems that improve arrhythmia episode detection specificity, such as, but not limited to, atrial fibrillation (AF) episode detection specificity. Such a method can include obtaining an ordered list of R-R intervals within a window leading up to a detection of a potential arrhythmia episode, determining a measure of a dominant repeated R-R interval pattern within the window, and comparing the measure of the dominant repeated R-R interval pattern to a pattern threshold. If the measure of the dominant repeated R-R interval pattern is below the pattern threshold, that is indicative of a regularly irregular pattern being present, and there is a determination that the detection of the potential arrhythmia episode does not correspond to an actual arrhythmia episode. Such embodiments can beneficially be used to significantly reduce the number of false positive arrhythmia detections.
    Type: Application
    Filed: March 28, 2023
    Publication date: September 21, 2023
    Applicant: Pacesetter, Inc.
    Inventors: Nima Badie, Fujian Qu, Jong Gill
  • Patent number: 11730378
    Abstract: Computer implemented methods, systems and devices are provided to monitor for potential heart failure (HF). Cardiac activity (CA) data is obtained and filtered to obtain respiration data indicative of a respiration pattern. The respiration data is analyzed to determine one or more respiration characteristics of interest (COI) that are recorded along with collection time information to form an HF monitoring log. Additionally or alternatively, the CA data is analyzed to detect an event of interest. The cardiac activity data is filtered to obtain respiration data indicative of a respiration pattern, and the respiration data is analyzed for respiration induced under detection of the event of interest from the CA data.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: August 22, 2023
    Assignee: Pacesetter, Inc
    Inventors: Stephanie C. Sun, Xiaoyi Min, Alan B. Vogel, Fujian Qu, Stuart Rosenberg
  • Patent number: 11647940
    Abstract: Described herein are methods, devices, and systems that improve arrhythmia episode detection specificity, such as, but not limited to, atrial fibrillation (AF) episode detection specificity. Such a method can include obtaining an ordered list of R-R intervals within a window leading up to a detection of a potential arrhythmia episode, determining a measure of a dominant repeated R-R interval pattern within the window, and comparing the measure of the dominant repeated R-R interval pattern to a pattern threshold. If the measure of the dominant repeated R-R interval pattern is below the pattern threshold, that is indicative of a regularly irregular pattern being present, and there is a determination that the detection of the potential arrhythmia episode does not correspond to an actual arrhythmia episode. Such embodiments can beneficially be used to significantly reduce the number of false positive arrhythmia detections.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: May 16, 2023
    Assignee: Pacesetter, Inc
    Inventors: Nima Badie, Fujian Qu, Jong Gill
  • Publication number: 20230135859
    Abstract: Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.
    Type: Application
    Filed: December 27, 2022
    Publication date: May 4, 2023
    Applicant: Pacesetter, Inc.
    Inventors: Nima Badie, Fujian Qu, Jong Gill
  • Patent number: 11633141
    Abstract: Computer implemented methods and systems for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains a far field cardiac activity (CA) data set that includes far field CA signals for beats. The method applies a feature enhancement function to the CA signals to form an enhanced feature in the CA data set. The method calculates an adaptive sensitivity level and sensitivity limit based on the enhanced feature from one or more beats within the CA data set and automatically iteratively analyzes a beat segment of interest by comparing the beat segment of interest to the current sensitivity level to determine whether one or more R-waves are present within the beat segment of interest.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: April 25, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Fady Dawoud, Fujian Qu, Stuart Rosenberg, Gene A. Bornzin, Jong Gill, Neha Malhotra, Xiaoyi Min
  • Publication number: 20230122269
    Abstract: Computer implemented methods and systems for detecting noise in cardiac activity are provided. The method and system obtain a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats, overlay a segment of the CA signals with a noise search window, and identify turns in the segment of the CA signals. The method and system determine whether the turns exhibit a turn characteristic that exceed a turn characteristic threshold, declare the segment of the CA signals as a noise segment based on the determining operation, shift the noise search window to a next segment of the CA signal and repeat the identifying, determining and declaring operations; and modify the CA signals based on the declaring the noise segments.
    Type: Application
    Filed: December 20, 2022
    Publication date: April 20, 2023
    Inventors: Jong Gill, Fujian Qu, Neha Malhotra, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud
  • Publication number: 20230117950
    Abstract: Computer implemented methods and systems are provided that comprise, under control of one or more processors of a medical device, where the one or more processors are configured with specific executable instructions. The methods and systems obtain motion data indicative of at least one of a posture or a respiration cycle; obtain cardiac activity (CA) signals for a series of beats; identify whether a characteristic of interest (COI) from at least a first segment of the CA signals exceeds a COI limit; analyze the motion data to determine whether at least one of the posture or respiration cycle at least in part caused the COI to exceed the COI limit. Based on the analyzing operation, the methods and systems automatically adjust a CA sensing parameter utilized by the medical device to detect R-waves in subsequent CA signals; and detect an arrhythmia based on a presence or absence of one or more of the R-waves in at least a second segment of the CA signals.
    Type: Application
    Filed: December 20, 2022
    Publication date: April 20, 2023
    Inventors: Donald Hopper, Luke C. McSpadden, Fujian Qu, Gene A. Bornzin, Sinny Delacroix
  • Patent number: 11564632
    Abstract: Computer implemented methods and systems for detecting noise in cardiac activity are provided. The method and system obtain a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats, overlay a segment of the CA signals with a noise search window, and identify turns in the segment of the CA signals. The method and system determine whether the turns exhibit a turn characteristic that exceed a turn characteristic threshold, declare the segment of the CA signals as a noise segment based on the determining operation, shift the noise search window to a next segment of the CA signal and repeat the identifying, determining and declaring operations; and modify the CA signals based on the declaring the noise segments.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: January 31, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Fujian Qu, Neha Malhotra, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud