Patents by Inventor Fumiaki Koizumi

Fumiaki Koizumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11371982
    Abstract: The purpose of the present invention is to provide a method for accurately predicting a cancer patient prognosis based on a count of desired cells for which expression of a leukocyte marker and an epithelial marker is hardly exhibited by detecting those cells. Provided is a method for diagnosing an overall survival prognosis for a patient suffering from cancer, the method including: a step of obtaining a concentrated solution containing desired cells by pre-treating a biological sample obtained from the patient; a step of optically detecting the concentrated cells; and a step of detecting the desired cells from the detected image, wherein an association is made with the overall survival prognosis diagnosis by counting the detected desired cells, and wherein the desired cells are cells confirmed by the existence of a cell nucleus and in which expression of a leukocyte marker and an epithelial marker is hardly exhibited.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: June 28, 2022
    Assignees: TOSOH CORPORATION, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Yasuyuki Akiyama, Atsushi Morimoto, Toru Futami, Fumiaki Koizumi, Takeshi Sawada
  • Patent number: 11280792
    Abstract: The object of the present invention is to provide an evaluation method capable of accurately determining a metastasis of cancer, the stage of cancer progression, or the malignancy of cancer.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: March 22, 2022
    Assignees: ON-CHIP BIOTECHNOLOGIES CO., LTD., SHIZUOKA PREFECTURE
    Inventors: Kazuo Takeda, Namiko Yamashita, Yuu Fujimura, Kaori Nishio, Yasuhiro Koh, Masaru Watanabe, Fumiaki Koizumi, Yuri Uehara
  • Patent number: 10684905
    Abstract: A disk device includes; a sensor that, when a driver that records and reads data in the disk device is in a non-operation state, detects an influence on the disk device; a determination circuit that determines based on a detection result of the sensor whether the detection result satisfies a condition leading to a failure of the disk device; and a transmitter that transmits information relating to a fact that the detection result satisfies the condition, to another device.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: June 16, 2020
    Assignee: NEC CORPORATION
    Inventor: Fumiaki Koizumi
  • Publication number: 20190025282
    Abstract: The purpose of the present invention is to provide a method for accurately predicting a cancer patient prognosis based on a count of desired cells for which expression of a leukocyte marker and an epithelial marker is hardly exhibited by detecting those cells. Provided is a method for diagnosing an overall survival prognosis for a patient suffering from cancer, the method including: a step of obtaining a concentrated solution containing desired cells by pre-treating a biological sample obtained from the patient; a step of optically detecting the concentrated cells; and a step of detecting the desired cells from the detected image, wherein an association is made with the overall survival prognosis diagnosis by counting the detected desired cells, and wherein the desired cells are cells confirmed by the existence of a cell nucleus and in which expression of a leukocyte marker and an epithelial marker is hardly exhibited.
    Type: Application
    Filed: January 19, 2017
    Publication date: January 24, 2019
    Applicants: TOSOH CORPORATION, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Yasuyuki AKIYAMA, Atsushi MORIMOTO, Toru FUTAMI, Fumiaki KOIZUMI, Takeshi SAWADA
  • Publication number: 20190011450
    Abstract: The object of the present invention is to provide an evaluation method capable of accurately determining a metastasis of cancer, the stage of cancer progression, or the malignancy of cancer.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 10, 2019
    Applicants: ON-CHIP BIOTECHNOLOGIES CO., LTD., SHIZUOKA PREFECTURE
    Inventors: Kazuo TAKEDA, Namiko YAMASHITA, Yuu FUJIMURA, Kaori NISHIO, Yasuhiro KOH, Masaru WATANABE, Fumiaki KOIZUMI, Yuri UEHARA
  • Publication number: 20180276066
    Abstract: A disk device includes; a sensor that, when a driver that records and reads data in the disk device is in a non-operation state, detects an influence on the disk device; a determination circuit that determines based on a detection result of the sensor whether the detection result satisfies a condition leading to a failure of the disk device; and a transmitter that transmits information relating to a fact that the detection result satisfies the condition, to another device.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 27, 2018
    Applicant: NEC Corporation
    Inventor: Fumiaki KOIZUMI
  • Patent number: 8981402
    Abstract: Disclosed are a white LED lighting device and an optical lens used in it. The white LED lighting device comprises a white LED and an optical lens. The white LED includes: a LED chip which emits blue light; and a fluorescent material which is excited by emission light of the LED chip and converts a wavelength into fluorescence of a complementary color of blue. The optical lens is formed with a scattering light guide which is given uniform scattering power in terms of a volume. The scattering light guide includes scattering particles for the scattering efficiency in a short wavelength range of light to be higher than that in a long wavelength range of light.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: March 17, 2015
    Assignees: Nittoh Kogaku K.K.
    Inventors: Yoshinori Shinohara, Fumiaki Koizumi
  • Publication number: 20150064722
    Abstract: The object of the present invention is to provide an evaluation method capable of accurately determining a metastasis of cancer, the stage of cancer progression, or the malignancy of cancer.
    Type: Application
    Filed: March 28, 2013
    Publication date: March 5, 2015
    Applicants: SHIZUOKA PREFECTURE, ON-CHIP BIOTECHNOLOGIES CO., LTD.
    Inventors: Kazuo Takeda, Namiko Yamashita, Yuu Fujimura, Kaori Nishio, Yasuhiro Koh, Masaru Watanabe, Fumiaki Koizumi, Yuri Uehara
  • Publication number: 20140080132
    Abstract: A method for predicting ADCC activity in a subject, the method comprising the steps of: (a) preparing a biological sample from the subject, said sample including a leukocyte, (b) bringing a portion of the biological sample and an antibody into contact with each other, (c) detecting expression of at least one marker of ADCC activity selected from the group consisting of tumor necrosis factor super family 15, chemokine CXCL3, and interleukin 6 in the leukocyte in (i) the portion of the sample brought into contact with the antibody and in (ii) another portion of the sample not brought into contact with the antibody, (d) comparing an expression level in portion (i) with the expression level in portion (ii); and (e) predicting presence of the cytotoxic activity when the expression level in portion (i) is higher than the expression level in portion (ii)
    Type: Application
    Filed: September 16, 2013
    Publication date: March 20, 2014
    Inventors: Kazuhiko Obara, Hiroshi Izutsu, Masato Mitsuhashi, Fumiaki Koizumi, Kenji Tamura, Mayu Yunokawa, Yasuo Kodera, Fumiko Taguchi
  • Patent number: 8579472
    Abstract: The present invention provides an illumination lens which suppresses a change of an illuminance distribution following a change of an arrangement position of a light source with respect to the illumination lens. A reflection surface and emission surface of the illumination lens are configured to refract and emit, in the emission surface, second illumination light and third illumination light with refracting power of different signs. By changing an illuminance distribution of third illumination light to cancel the change of an illuminance distribution of the second illumination light when a light source is moved, it is possible to suppress the change of the illuminance distribution small even when the light source is moved back and forth.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: November 12, 2013
    Assignee: Nittoh Kogaku K.K.
    Inventor: Fumiaki Koizumi
  • Publication number: 20130085081
    Abstract: Disclosed are a method of detecting the presence or absence of a single nucleotide polymorphism of a gene, for prediction of the risk of developing drug-induced lung injury, or for improving a therapeutic method, and a kit for carrying out the detection method. The detection method is characterized by comparing an ABCB1 gene in a biological sample with a wild-type ABCB1 gene to detect the presence or absence of a single nucleotide polymorphism in the ABCB1 gene in the biological sample, in particular, by determining the nucleotide at position 3751 of the CDS of the ABCB1 gene. The kit comprises an oligonucleotide probe which specifically binds to a single nucleotide polymorphism in an ABCB1 gene under selective binding conditions, or an oligonucleotide primer which amplifies a nucleic acid sequence comprising a single nucleotide polymorphism in an ABCB1 gene.
    Type: Application
    Filed: June 8, 2011
    Publication date: April 4, 2013
    Applicants: National Cancer Center, Kinki University, Mitsubishi Chemical Medience Corporation
    Inventors: Fumiaki Koizumi, Shintaro Kanda, Tomohide Tamura, Koichi Goto, Masaru Sekijima, Akira Ohide, Kazuto Nishio
  • Publication number: 20120286314
    Abstract: Disclosed are a white LED lighting device and an optical lens used in it. The white LED lighting device comprises a white LED and an optical lens. The white LED includes: a LED chip which emits blue light: and a fluorescent material which is excited by emission light of the LED chip and converts a wavelength into fluorescence of a complementary color of blue. The optical lens is formed with a scattering light guide which is given uniform scattering power in terms of a volume. The scattering light guide includes scattering particles for the scattering efficiency in a short wavelength range of light to be higher than that in a long wavelength range of light.
    Type: Application
    Filed: January 4, 2011
    Publication date: November 15, 2012
    Applicants: NITTOH KOGAKU K.K.
    Inventors: Yoshinori Shinohara, Fumiaki Koizumi
  • Publication number: 20120113653
    Abstract: The present invention provides an illumination lens which suppresses a change of an illuminance distribution following a change of an arrangement position of a light source with respect to the illumination lens. A reflection surface and emission surface of the illumination lens are configured to refract and emit, in the emission surface, second illumination light and third illumination light with refracting power of different signs. By changing an illuminance distribution of third illumination light to cancel the change of an illuminance distribution of the second illumination light when a light source is moved, it is possible to suppress the change of the illuminance distribution small even when the light source is moved back and forth.
    Type: Application
    Filed: October 25, 2011
    Publication date: May 10, 2012
    Applicant: NITTOH KOGAKU K.K.
    Inventor: Fumiaki KOIZUMI
  • Patent number: 6972903
    Abstract: A vision assisting apparatus includes a casing for forming an inversely U-shaped optical path, a light entry, provided at one end of the optical path, through which light enters, a light exit, provided at another end of the optical path, through which light exits in an opposite direction to the light entry, an optical system for processing an image entered via the light entry by using the optical pass and outputting a processed image via the light exit, and attaching structure for attaching the casing to a wearer so that the light exit is positioned close to an eye of the wearer. By forming the inversely U-shaped optical path with the casing, it is possible to provide a sufficiently long optical path in a compact form.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: December 6, 2005
    Assignees: Nittoh Kogaku K.K.
    Inventors: Hideo Hara, Kazunaga Shimizu, Fumiaki Koizumi, Yasuhiro Sakai
  • Publication number: 20040179261
    Abstract: The vision assisting apparatus of the present invention includes a casing for forming an inversely U-shaped optical path, a light entry, provided at one end of the optical path, through which light enters, a light exit, provided at another end of the optical path, through which light exits in an opposite direction to the light entry, an optical system for processing an image entered via the light entry by using the optical pass and outputting a processed image via the light exit, and means for attaching the casing to a wearer so that the light exit is positioned close to an eye of the wearer. By forming the inversely U-shaped optical path with the casing, it is possible to provide a sufficiently long optical path in a compact form.
    Type: Application
    Filed: April 26, 2004
    Publication date: September 16, 2004
    Inventors: Hideo Hara, Kazunaga Shimizu, Fumiaki Koizumi, Yasuhiro Sakai
  • Patent number: 6678538
    Abstract: The remaining level of a battery 9 is detected, and when the remaining level is lower than a specified value, supply of power is stopped to other circuits except necessary circuits 5, 7, 10 that need electric power for reading out a telephone number from a telephone number memory 13 and displaying the read out telephone number. Only the telephone directory function is remaining, and if the battery is spend and the portable telephone can not be used, at least a worst case of impossibility of any operation can be avoided. The specified value is a voltage level at which it is usually difficult to transmit and receive. The necessary circuits include the telephone number memory 13 and the display unit 7 for displaying the telephone number. It is further preferred to display it is impossible to transmit and receive, and possible to display the telephone number.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: January 13, 2004
    Assignee: NEC Corporation
    Inventor: Fumiaki Koizumi
  • Patent number: 6678372
    Abstract: A telephone terminal is connected to a line network and has an individual terminal number. The telephone terminal comprises a clock section for measuring date and hour. A memory section is for memorizing a call telephone number as a communication telephone number on call. The memory section is for memorizing a reception telephone number as the communication telephone number on reception. The memory section further memorizes communication information in correspondence to the communication telephone number. The communication information and the communication telephone number are displayed on a display section. A control section controls the memory section to make the memory section memorize the communication information in correspondence to the communication telephone number. The control section controls the display section to make the display section display the communication telephone number and the communication information.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: January 13, 2004
    Assignee: NEC Corporation
    Inventor: Fumiaki Koizumi
  • Patent number: 6504868
    Abstract: Since a conventional adaptive equalizer handles an update quantity control parameter &mgr; as a fixed value, the update quantity control parameter &mgr; is not optimized adaptively to variation of a channel state and the BER characteristic is deteriorated.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: January 7, 2003
    Assignee: NEC Corporation
    Inventor: Fumiaki Koizumi
  • Patent number: 6240145
    Abstract: In outputting the decision results of decoding of a received signal by the maximum likelihood serial estimation using Viterbi algorithm, a channel estimation section estimates the channel state. The magnitude and delay quantity of delay wave contained in the received signal are determined, by a control section for the number of states, from the channel state estimated by the channel estimation section to determine the necessary number of states in Viterbi decoding, and decoding is controlled by the number of states. A viterbi decoder carries out the decoding according to the control based on the number of states determined by the control section for the number of states. By virtue of this constitution, when the transmission quality of the channel is good, the quantity of computation in the Viterbi decoder is reduced to reduce the power consumption and, at the same time, the quantity of the computation is minimized to realize high speed processing.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: May 29, 2001
    Assignee: NEC Corporation
    Inventor: Fumiaki Koizumi
  • Patent number: 5995562
    Abstract: In a maximum-likelihood decoder, a reliability information of decoded data corresponding to a maximum-likelihood path is generated by using state codes previously assigned to the trellis states, respectively. After a survivor path is selected for each of the trellis states according to Viterbi algorithm, the survivor path is stored, and then a maximum-likelihood path is selected from the survivor paths stored. Based on at least two state codes each corresponding to a different trellis state, a reliability value is generated as the reliability information. Since the assigned state codes are used to generate the reliability information, the reliability criterion of decoded data is kept substantially at constant even when the conditions of input signals are changed, resulting in improved reliability of decoded data.
    Type: Grant
    Filed: October 24, 1996
    Date of Patent: November 30, 1999
    Assignee: NEC Corporation
    Inventor: Fumiaki Koizumi