Patents by Inventor Fumio Hirose

Fumio Hirose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions containing a derivative of para-aminobenzoic acid as an active ingredient
    Patent number: 4957906
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R donotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: September 18, 1990
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition containing a derivative of para-aminobenzoic acid as an active ingredient
    Patent number: 4874750
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R donotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 17, 1986
    Date of Patent: October 17, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Method for inhibiting the formation of urinary calculus utilizing 24,25-(OH).sub.2 -D.sub.3
    Patent number: 4866047
    Abstract: Disclosed herein is a method for inhibiting the formation of urinary calculus by the administration of 24,25-dihydroxycholecarciferol.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: September 12, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Hideyuki Yamato, Yuji Maeda, Takayoshi Fujii, Yasuhiko Kobayashi, Kenichi Saito, Fumio Hirose, Tadaaki Kato, Chikao Yoshikumi
  • Nitrogen-containing polysaccharide
    Patent number: 4851395
    Abstract: Disclosed is nitrogen-containing polysaccharide substantially free of units having a molecular weight below about 5,000, said nitrogen-containing polysaccharide having been extracted from Coriolus versicolor (Fr.) Quel., substantially all polymer units having a molecular weight below about 5,000 having been removed therefrom, which exhibits antitumor and immunological activity.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: July 25, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kausha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Yoshio Omura, Takayoshi Fujii, Toshihiko Wada, Eiichi Takahashi, Fumio Hirose
  • Pharmaceutical composition containing para-amino-benzoic acid-N-D-xyloside as an active ingredient
    Patent number: 4801581
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-D-xyloside or a pharmaceutically a acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: March 22, 1985
    Date of Patent: January 31, 1989
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohara, Takao Ando
  • Pharmaceutical composition containing para-amino-benzoic acid-N-D-xyloside as an active ingredient
    Patent number: 4757054
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-D-xyloside or a pharmaceutically a acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: January 7, 1987
    Date of Patent: July 12, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohara, Takao Ando
  • Method for the treatment of tumors
    Patent number: 4748159
    Abstract: Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or tumor, which comprises administering to a patient suffering therefrom a pharmaceutically effective amount of p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 24, 1986
    Date of Patent: May 31, 1988
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition containing a derivative of orthoaminobenzoic acid as an active ingredient
    Patent number: 4708950
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, xylose, glucose, galactose, rhamnose and mannose, and .sup.2 R denotes hydrogen or methyl group, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 27, 1984
    Date of Patent: November 24, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Nitrogen-containing polysaccharide
    Patent number: 4699787
    Abstract: A method of restoring the immune response of a patient having a lowered immune response level is provided, in which the patient is given an effective amount of certain nitrogen-containing polysaccharides derived from Coriolus versicolor (Fr.) Quel, where the polymer units having a molecular weight of below about 5,000 have been removed therefrom.
    Type: Grant
    Filed: March 6, 1984
    Date of Patent: October 13, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Yoshio Omura, Takayoshi Fujii, Toshihiko Wada, Eiichi Takahashi, Fumio Hirose
  • Pharmaceutical composition containing a derivative of para-aminobenzoic acid as an active ingredient
    Patent number: 4673669
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R donotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 11, 1985
    Date of Patent: June 16, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • P-aminobenzoic acid-N-L-rhamnoside pharmaceutical compositions for treating inflammatory diseases
    Patent number: 4663312
    Abstract: Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or tumor, which comprises administering to a patient suffering therefrom a pharmaceutically effective amount of p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 26, 1985
    Date of Patent: May 5, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition containing para-aminobenzoic acid-N-L-rhamnoside as an active ingredient
    Patent number: 4657895
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-L-rhamonoside or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: September 4, 1985
    Date of Patent: April 14, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Method for the treatment of pains or pyrexia due to the accentuation of central nerve
    Patent number: 4649133
    Abstract: Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or tumor, which comprises administering to a patient suffering therefrom a pharmaceutically effective amount of p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 26, 1985
    Date of Patent: March 10, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition containing a derivative of para-aminobenzoic acid as an active ingredient
    Patent number: 4637998
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 20, 1981
    Date of Patent: January 20, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains or pyrexia due to the accentuation of central nerve, or tumor
    Patent number: 4596794
    Abstract: Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or tumor, which comprises administering to a patient suffering therefrom a pharmaceutically effective amount of p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 27, 1984
    Date of Patent: June 24, 1986
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition containing a derivative of para-aminobenzoic acid as an active ingredient
    Patent number: 4569842
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 26, 1982
    Date of Patent: February 11, 1986
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition containing para-aminobenzoic acid-N-L-rhamnoside as an active ingredient
    Patent number: 4559327
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-L-rhamonoside or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: April 13, 1983
    Date of Patent: December 17, 1985
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Method for the treatment of hyperglycemia using p-aminobenzoate-N-L-rhamnoside
    Patent number: 4555505
    Abstract: Disclosed is a method for the treatment of hyperglycemia, hyperlipemia, inflammatory diseases, pains due to the accentuation of central nerve, pyrexia due to the accentuation of central nerve or tumor, which comprises administering to a patient suffering therefrom a pharmaceutically effective amount of p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 29, 1984
    Date of Patent: November 26, 1985
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohara, Takao Ando
  • Pharmaceutical composition containing a derivative of ortho-aminobenzoic acid as an active ingredient
    Patent number: 4450156
    Abstract: Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, xylose, glucose, galactose, rhamnose and mannose, and .sup.2 R denotes hydrogen or methyl group, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 20, 1981
    Date of Patent: May 22, 1984
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Pharmaceutical composition comprising derivative of aminobenzoic acid for regulating prostaglandin
    Patent number: 4440757
    Abstract: A pharmaceutical composition for regulating prostagrandins, which comprises (a) a derivative of aminobenzoic acid, represented by the following general formula: ##STR1## wherein R.sup.1 denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha)-or 1(beta) position from arabinose, xylose, rhamnose, glucose, galactose, mannose and fructose, and R.sup.2 is a hydrogen atom, an alkyl group of one to four carbon atoms or a pharmaceutically acceptable metal, and (b) a pharmaceutically acceptable carrier or diluent of (a) is disclosed.
    Type: Grant
    Filed: August 1, 1980
    Date of Patent: April 3, 1984
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando