Patents by Inventor Fumio Hirose

Fumio Hirose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4380536
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-D-mannoside or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: August 5, 1980
    Date of Patent: April 19, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4372948
    Abstract: The novel derivatives of saccharide obtained by bringing a saccharide into reaction with an ester of aminobenzoic acid, an aminobenzoic acid amide, an aminophenylacetic acid or an ester thereof have various physiological activities.
    Type: Grant
    Filed: March 25, 1981
    Date of Patent: February 8, 1983
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Fumio Hirose, Yoshio Ohmura, Takayoshi Fujii, Masanori Ikuzawa, Kenichi Matsunaga, Takao Ando, Minoru Ohhara
  • Patent number: 4322408
    Abstract: Disclosed is a pharmaceutical composition useful in the treatment of hypertension containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 2, 1979
    Date of Patent: March 30, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4322409
    Abstract: Disclosed is a pharmaceutical composition useful for the treatment of hypertension containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: ##STR1## wherein .sup.1 R denotes one member selected from the group consisting of the residual groups formed by removing OH at 1(alpha) or 1(beta) position from arabinose, xylose, glucose, galactose, rhamnose and mannose, and .sup.2 R denotes hydrogen or methyl group, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 12, 1979
    Date of Patent: March 30, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4315921
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-D-xyloside or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: December 10, 1979
    Date of Patent: February 16, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4313939
    Abstract: Disclosed is a pharmaceutical composition containing p-aminobenzoic acid-N-L-rhamnoside or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: December 11, 1979
    Date of Patent: February 2, 1982
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando
  • Patent number: 4229570
    Abstract: The fungi belonging to the Coriolus genus is first extracted with water or a dilute alkaline solution and then further extracted stepwise by using alkaline solutions with gradually increased concentrations to obtain a nitrogen-containing polysaccharide having an anti-tumor activity in a high yield.
    Type: Grant
    Filed: April 19, 1977
    Date of Patent: October 21, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Fumio Hirose, Yoshio Omura, Toshihiko Wada, Takayoshi Fujii, Eiichi Takahashi
  • Patent number: 4202969
    Abstract: The fungi belonging to the Coriolus genus are extracted by using a dilute alkaline solution having a concentration within a certain specified range whereby the low molecular weight substances with molecular weight of less than 5,000 are obtained in there extract solution. These low molecular weight substances are separated from the extract solution to obtain a nitrogen-containing polysaccharide having excellent anti-tumor activity.
    Type: Grant
    Filed: April 19, 1977
    Date of Patent: May 13, 1980
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Saburo Ueno, Chikao Yoshikumi, Fumio Hirose, Yoshio Omura, Toshihiko Wada, Takayoshi Fujii, Eiichi Takahashi
  • Patent number: 4051314
    Abstract: Polysaccharides are produced by purifying a liquid extract of a mycelium of a strain of fungus species belonging to the class Basidiomycetes or the filtered broth of a cultured medium in which a mycelium of a selected strain of Basidiomycetes has been incubated; the polysaccharides exhibiting an anticarcinogenic activity in mice.
    Type: Grant
    Filed: October 11, 1974
    Date of Patent: September 27, 1977
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Shigeto Ohtsuka, Saburo Ueno, Chikao Yoshikumi, Fumio Hirose, Yoshio Ohmura, Toshihiko Wada, Takayoshi Fujii, Eiichi Takahashi