Patents by Inventor Fumitaka Ito
Fumitaka Ito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5984764Abstract: The present invention relates to a method of discovering optimal conditions such as the rotational speed ratio of an abrasive cloth and a dresser, to improve the flatness of the abrasive cloth after it has been dressed. A narrow annular dresser having an inner diameter of at least the width of a wide annular utilization region of the abrasive cloth is pressed while rotating against the abrasive cloth which is fixed onto a turn table. A rotational motion is imparted to the abrasive cloth in the same direction as the rotation of the dresser and at a predetermined rotational speed. The abrasive cloth is dressed thereby in such a manner that there is a uniform distribution of distances through which the grindstone slides over various points within the utilization region of the abrasive cloth.Type: GrantFiled: May 21, 1997Date of Patent: November 16, 1999Assignee: Toshiba Kikai Kabushiki KaishaInventors: Hideo Saito, Hiromi Nishihara, Fumitaka Ito, Hironobu Hirata
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Patent number: 5952369Abstract: A compound of formula (I) ##STR1## and its pharmaceutically acceptable salt, wherein A is hydrogen or OY, wherein Y is a hydroxy protecting group; Ar is phenyl optionally substituted with one or more substituents selected from halo, hydroxy, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, CF.sub.3, C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkyloxy and carboxy-C.sub.1 -C.sub.4 alkyloxy;X is phenyl, naphthyl, biphenyl, indanyl, benzofuranyl, benzothiophenyl, 1-tetralone-6-yl,C.sub.1 -C.sub.4 alkylenedioxy, pyridyl, furyl and thienyl these groups optionally being substituted with up to three substituents selected from halo, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, hydroxy, NO.sub.2, CF.sub.3 and SO.sub.2 CH.sub.3 ; andR is hydrogen, C.sub.1 -C.sub.4 alkyl or a hydroxy protecting group.Type: GrantFiled: September 26, 1997Date of Patent: September 14, 1999Assignee: Pfizer IncInventor: Fumitaka Ito
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Patent number: 5939433Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is methoxy and R.sup.2 is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl; and the pharmaceutically acceptable salts of such compounds.These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.Type: GrantFiled: April 30, 1997Date of Patent: August 17, 1999Assignee: Pfizer IncInventors: Fumitaka Ito, Hiroshi Kondo, Masami Nakane, Kaoru Shimada, John Adams Lowe, III, Terry Jay Rosen
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Patent number: 5886009Abstract: This invention relates to the quinuclidine derivative (2S, 3S)-N-(5-n-propyl-2-methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo?2.2 .2!octan-3-amine and its pharmaceutically acceptable salts. These compounds are substance P antagonists and are useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.Type: GrantFiled: June 19, 1995Date of Patent: March 23, 1999Assignee: Pfizer Inc.Inventors: Fumitaka Ito, Hiroshi Kondo, Masami Nakane, Kaoru Shimada
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Patent number: 5859011Abstract: Compound of formula (1) and their pharmaceutically acceptable salts wherein A1,A2,R1, R2,R3,R4,X are as defined in the specification have excellent bradykinin antagonistic activity.Type: GrantFiled: July 1, 1997Date of Patent: January 12, 1999Assignee: Pfizer Inc.Inventors: Fumitaka Ito, Hiroshi Kondo, David L. Hageman, John A. Lowe, III, Susumu Nakanishi, Fredric J. Vinick
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Patent number: 5852038Type: GrantFiled: November 18, 1996Date of Patent: December 22, 1998Assignee: Pfizer IncInventors: Fumitaka Ito, Toshihide Kokura, Masami Nakane, Kunio Satake, Hiroaki Wakabayashi
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Patent number: 5837720Abstract: A compound of formula (I): ##STR1## and its pharmaceutically acceptable salt, wherein R is hydrogen or hydroxy; Ar is unsubstituted or substituted phenyl; X is unsubstituted or substituted phenyl or heterocyclic, mono-, di- or trihalomethyl, cyano, or the like; and X.sup.2 is phenyl, naphthyl, furyl, thienyl, pyridyl, thiazolyl, benzofuryl or benzothienyl, each of which may either be unsubstituted or substituted. These compounds have agonist activity toward opioid kappa receptors and are thus useful as analgesic, anti-inflammatory, diuretic and neuroprotective agents.Type: GrantFiled: April 17, 1997Date of Patent: November 17, 1998Assignee: Pfizer Inc.Inventor: Fumitaka Ito
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Patent number: 5837711Abstract: Certain novel substituted quinuclidine compounds having the ability to antagonize substance P and having the following formula: ##STR1## wherein Ar.sup.1 and Ar.sup.2 are each, independently, thienyl, phenyl, fluorophenyl, chlorophenyl or bromophenyl;X is --CONR.sup.3 R.sup.4, --CO.sub.2 R.sup.3, --CH.sub.2 OR.sup.3, --CH.sub.2 NR.sup.3 R.sup.4 or --CONR.sup.3 OR.sup.4 ;R.sup.1, R.sup.3 and R.sup.4 are each, independently, hydrogen or alkyl having 1 to 4 carbon atoms;R.sup.Type: GrantFiled: April 28, 1995Date of Patent: November 17, 1998Assignee: Pfizer Inc.Inventors: Fumitaka Ito, Toshihide Kokura, Masami Nakane, Kunio Satake, Hiroaki Wakabayashi
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Patent number: 5837717Abstract: A compound of the following formula: ##STR1## and its pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.3-7 cycloalkyl, C.sub.2-4 alkenyl, C.sub.1-4 alkoxy, C.sub.1-4 alkylthio, phenyl or phenyl-C.sub.1-4 alkyl; or R.sup.1 and R.sup.2 are taken together with the nitrogen to which they are attached and form optionally substituted, saturated or unsaturated 3-, 4-, 5-, 6- or 7-membered heterocyclic cantaining one to two heteroatoms, provided that the heterocyclic is not pyrrolidinyl;R.sup.3 is hydrogen, C.sub.1-4 alkyl or a hydroxy protecting group;Ar is phenyl optionally substituted with one or more substituents selected from halo, hydroxy, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkoxy-C.sub.1-4 alkyloxy, CF.sub.3 and carboxy-C.sub.1-4 alkyloxy; andX is phenyl, naphthyl, biphenyl, indanyl, benzofuranyl, benzothiophenyl, 1-tetralone-6-yl, C.sub.Type: GrantFiled: January 28, 1997Date of Patent: November 17, 1998Assignee: Pfizer Inc.Inventor: Fumitaka Ito
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Patent number: 5834478Abstract: This invention provides a compound of the following formula: ##STR1## and the pharmaceutically acceptable salts thereof, wherein R is hydrogen, C.sub.1 -C.sub.5 alkyl or an O-protecting group; B is a dircet bond, C.sub.1 -C.sub.5 alkylene or C.sub.2 -C.sub.5 alkenylene; R.sup.1 is C.sub.1 -C.sub.5 alkyl, C.sub.2 -C.sub.5 alkenyl or C.sub.3 -C.sub.7 cycloalkyl-C.sub.1 -C.sub.3 alkyl; R.sup.2 is hydroxy or C.sub.1 -C.sub.5 alkoxy; R.sup.3 is hydrogen, hydroxy or C.sub.1 -C.sub.5 alkoxy; and R.sup.4 is hydrogen, phenyl or heteroaryl selected from furyl, thienyl and pyrrolyl, the phenyl and heteroaryl being optionally substituted by one to five substitutents selected from halo, hydroxy, C.sub.1 -C.sub.3 allyl, C.sub.1 -C.sub.3 alkoxy and C.sub.2 -C.sub.5 alkenyl.Type: GrantFiled: September 12, 1997Date of Patent: November 10, 1998Assignee: Pfizer Inc.Inventor: Fumitaka Ito
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Patent number: 5807867Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is methoxy and R.sup.2 is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl; and the pharmaceutically acceptable salts of such compounds.These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.Type: GrantFiled: May 23, 1994Date of Patent: September 15, 1998Assignee: Pfizer Inc.Inventors: Fumitaka Ito, Hiroshi Kondo, Masami Nakane, Kaoru Shimada, John Adams Lowe, III, Terry Jay Rosen
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Patent number: 5748715Abstract: A facsimile apparatus which utilizes a dialing signal of a tone signal and can be used as a called-side communication apparatus to print desired character string information through a simple operation of a calling-side telephone set, and also a facsimile communication method in the facsimile apparatus. In the called-side facsimile apparatus, a character string information memory stores therein a plurality of character string information and unique numbers associated therewith; whereas a character information memory stores therein image information corresponding to the respective character string information. When a user of the calling-side communication apparatus enters a number corresponding to desired character string information, this causes a dialing signal indicative of the number to be transmitted to the facsimile apparatus.Type: GrantFiled: September 21, 1995Date of Patent: May 5, 1998Assignee: Hitachi, Ltd.Inventors: Tetsuo Shinagawa, Yumiko Watanabe, Akio Shinagawa, Fumitaka Ito
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Patent number: 5721255Abstract: The present invention relates to novel substituted benzylamino nitrogen containing non-aromatic heterocycles and, specifically, to compounds of the formula ##STR1## wherein W, R.sup.1, R.sup.2, R.sup.3 and A are as defined in the specification, and to intermediates used in the synthesis of such compounds. The novel compounds of formula I are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.Type: GrantFiled: February 15, 1995Date of Patent: February 24, 1998Assignee: Pfizer Inc.Inventors: Harry R. Howard, Masami Nakane, Masaya Ikunaka, Kunio Satake, Terry J. Rosen, John A. Lowe, III, Brian T. O'Neill, Fumitaka Ito
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Patent number: 5716965Abstract: Compounds of the formula ##STR1## wherein W, Ar.sup.1, Ar.sup.2 and Ar.sup.3 are defined as below; and the pharmaceutically acceptable salts of such compounds.These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain.Type: GrantFiled: December 20, 1993Date of Patent: February 10, 1998Assignee: Pfizer Inc.Inventors: Fumitaka Ito, Toshihide Kokura, Masami Nakane, Kunio Satake, Hiroaki Wakabayashi
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Patent number: 5604241Abstract: Compounds useful in the treatment of inflammatory disorders, central nervous system disorders and other disorders of the formula I ##STR1## and the pharmaceutically-acceptable salts thereof, wherein Ar.sup.1 and Ar.sup.2 are each independently aryl or substituted aryl; R.sup.1 is alkyl having from 1 to 6 carbon atoms;R.sup.Type: GrantFiled: April 20, 1995Date of Patent: February 18, 1997Assignee: Pfizer Inc.Inventors: Fumitaka Ito, Kunio Satake, Kaoru Shimada
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Patent number: 5592189Abstract: An apparatus for use in offices includes a planar liquid crystal shutter disposed at least a portion of a surface of a housing of the apparatus, the shutter being set to a transparent state or a non-transparent state depending on an input signal supplied thereto, and a controller for applying to the shutter a control signal to control the transparent or non-transparent state thereof.Type: GrantFiled: June 6, 1995Date of Patent: January 7, 1997Assignee: Hitachi, Ltd.Inventors: Soshiro Kuzunuki, Yasuro Hori, Shuichi Okabe, Fumitaka Ito
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Patent number: 5377257Abstract: A facsimile apparatus which carries out ringing of a telephone first for calling, and transmits a voice message informing of "absence" and "facsimile receivable" to a calling station when offhook is not detected during a predetermined period. The facsimile apparatus also transmits a called station identification signal CED after a silence interval of about 5 seconds. When the calling station onhooks a handset during the period of ringing of the telephone by judging that the called station is absent, a fee for a telephone call will not be charged. Furthermore, by setting the silence interval, the CED signal after the voice message is prevented from being heard by the calling station.Type: GrantFiled: November 6, 1992Date of Patent: December 27, 1994Assignee: Hitachi, Ltd.Inventors: Manabu Shirasaka, Teiji Okamoto, Fumitaka Ito, Yasuyuki Kozima
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Patent number: 5341413Abstract: A communication equipment has a dictionary file for areas and destination names corresponding to destination numbers entered by a destination entry unit such as a dialer. The dictionary file is looked up by a retrieval unit during the entry of the number and the retrieved area name and destination name are informed by an informing unit so that an entry error of the area name and the destination name can be detected during the entry of the destination and the error is corrected.Type: GrantFiled: August 20, 1992Date of Patent: August 23, 1994Assignee: Hitachi, Ltd.Inventors: Yasuro Hori, Soshiro Kuzunuki, Shuichi Okabe, Fumitaka Ito
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Patent number: 5166161Abstract: 3-Oxo-4-acyl or carbamyl-bicyclic aromatic and heterocyclic compounds as inhibitors of cyclooxygenase and lipoxygenase and useful as antiallergy and antiinflammatory agents.Type: GrantFiled: January 22, 1991Date of Patent: November 24, 1992Assignee: Pfizer Inc.Inventors: Toshihide Kokura, Kazunari Nakao, Fumitaka Ito, Masami Nakane
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Patent number: 5086062Abstract: This invention relates to certain benzoxazolinones which inhibit lipoxygenase and/or cyclooxygenase enzymes. Such compounds are useful in inhibiting such enzymes, per se, and are useful in treating allergic and inflammatory conditions in a mammal. This invention also relates to methods of inhibiting lipoxygenase and/or cyclooxygenase in a mammal with such benzoxazolinones; methods of treating an allergic condition in a mammal with such compounds; methods of treating an inflammatory condition in a mammal with such compounds; and pharmaceutical compositions comprising the benzoxazolinones hereof.Type: GrantFiled: May 29, 1990Date of Patent: February 4, 1992Assignee: Pfizer Inc.Inventors: Kazuo Ando, Nobuko Asai, Fumitaka Ito, Takashi Mano, Masami Nakane, Kunio Satake, Kaoru Shimada