Abstract: Disclosed are effective methods for activating, washing, specifically extracting and purifying cannabinoids from Cannabis plant tissues using heat activation, washing impurities away with a polar solvent, optionally modified with an organic acid, base, surfactant or inorganic salt, extracting the activated non-polar cannabinoids with a potable selective solvent such as ethanol. The extracted active ingredients may be purified by chromatography and detected and quantified by mass spectrometry with external or isotopic or otherwise labelled standards.

Abstract: A method of immobilizing extracellular vesicles in an extracellular matrix material provides for improved extracellular vesicle retention in vitro and in vivo. Extracellular matrix materials, such as collagen, are functionalized with chemicals that are complimentary to ligands disposed on the surface of the extracellular vesicle. In one example embodiment, collagen is functionalized with dibenzocyclooctyne and the extracellular vesicle is functionalized with an azide tag. The extracellular vesicle is immobilized within the collagen through a click reaction involving the dibenzocyclooctyne and the azide tag.

Abstract: Disclosed here is a capacitive deionization device for removing ions from a target solution. The capacitive deionization device includes a first porous electrode, a second porous electrode, a first header plate, a second header plate, and a sealant. The second porous electrode is disposed below and spaced from the first porous electrode. The first header plate is disposed on the first porous electrode. The first header plate defines an input flow channel that is in fluidic communication with the first porous electrode. The second header plate is disposed below the second porous electrode. The second header plate defines an output flow channel that is in fluidic communication with the second porous electrode. The sealant is disposed between the first header plate and the second header plate and surrounds the first porous electrode and the second porous electrode.

Abstract: Disclosed here is a capacitive deionization device for removing ions from a target solution. The capacitive deionization device includes a first porous electrode, a second porous electrode, a first header plate, a second header plate, and a sealant. The second porous electrode is disposed below and spaced from the first porous electrode. The first header plate is disposed on the first porous electrode. The first header plate defines an input flow channel that is in fluidic communication with the first porous electrode. The second header plate is disposed below the second porous electrode. The second header plate defines an output flow channel that is in fluidic communication with the second porous electrode. The sealant is disposed between the first header plate and the second header plate and surrounds the first porous electrode and the second porous electrode.

Abstract: A mold for encapsulating an electrical component. The mold includes an encapsulation chamber and an air inlet. The encapsulation chamber is defined by a housing, an open top, and a solid bottom. The housing includes a solid outer wall, a permeable inner wall, and an air chamber between the solid outer wall and the inner wall. The air inlet is configured to introduce a gas into the air chamber. The encapsulation chamber is sized and shaped to receive the electrical component while leaving a gap for the introduction of encapsulant around the electrical component. The encapsulant may be silicone rubber. To remove an encapsulated electrical component, pressurized air may be introduced through the air inlet into the air chamber, passing through the permeable inner wall, separating the outer surface of the encapsulant from the housing, and allowing the combination casting to be removed from the mold.

Abstract: Disclosed here is a method for making a nanoporous material, comprising aerosolizing a solution comprising at least one metal salt and at least one solvent to obtain an aerosol, freezing the aerosol to obtain a frozen aerosol, and drying the frozen aerosol to obtain a nanoporous metal compound material. Further, the nanoporous metal compound material can be reduced to obtain a nanoporous metal material.

Abstract: Provided herein are tethered extracellular vesicles and methods of making tethered extracellular vesicles.

Abstract: A mold for encapsulating an electrical component. The mold includes an encapsulation chamber and an air inlet. The encapsulation chamber is defined by a housing, an open top, and a solid bottom. The housing includes a solid outer wall, a permeable inner wall, and an air chamber between the solid outer wall and the inner wall. The air inlet is configured to introduce a gas into the air chamber. The encapsulation chamber is sized and shaped to receive the electrical component while leaving a gap for the introduction of encapsulant around the electrical component. The encapsulant may be silicone rubber. To remove an encapsulated electrical component, pressurized air may be introduced through the air inlet into the air chamber, passing through the permeable inner wall, separating the outer surface of the encapsulant from the housing, and allowing the combination casting to be removed from the mold.

Abstract: Disclosed here is a method for producing a graphene macro-assembly (GMA)-fullerene composite, comprising providing a mixture of graphene oxide and water, adding a hydroxylated fullerene to the mixture, and forming a gel of the hydroxylated fullerene and the mixture. Also described are a GMA-fullerene composite produced, an electrode comprising the GMA-fullerene composite, and a supercapacitor comprising the electrode.

Abstract: There is provided a diffuser for a turbine, comprising: a support configured to mount to a turbine housing; a diffuser body configured to receive fluid from an outlet of the turbine, the diffuser body defining a longitudinal axis and having a perimeter with a length measured in a plane normal to the longitudinal axis; and a bridge configured to connect the support to the diffuser body, wherein the connection between the bridge and the diffuser body is confined to a continuous portion of the perimeter of the diffuser body that is not more than around 50% of the total length of the perimeter of the diffuser body.

Abstract: A system and method used to fabricate an implant from cartilage, where the implant can be used in reconstructive surgery. The system includes a thermoregulation device capable of maintaining a desired temperature range during milling operations. The milling machine is controlled by instructions generated from a digital model of the implant. The digital model can be a stock model or a custom model created from medical scans.

Abstract: Antibodies that bind to ?v?8 are provided.

Abstract: Disclosed here is a method for making a three-dimensional micro-architected aerogel, comprising: (a) curing a reaction mixture comprising a co-sol-gel material (e.g., graphene oxide (GO)) and at least one catalyst to obtain a crosslinked co-sol-gel (e.g., GO hydrogel); (b) providing a photoresin comprising a solvent, a photoinitiator, a crosslinkable polymer precursor, and a dispersion of the crosslinked co-sol-gel (e.g., GO hydrogel); (c) curing the photoresin using projection microstereolithography layer-by-layer to produce a wet gel having a pre-designed three-dimensional structure; (d) drying the wet gel to produce a dry gel; and (e) pyrolyzing the dry gel to produce a three-dimensional micro-architected aerogel (e.g., graphene aerogel). Also disclosed is a photoresin for projection microstereolithography, comprising a solvent, a photoinitiator, a crosslinkable polymer precursor, and a dispersion of a crosslinked co-sol-gel.

Abstract: A mold for encapsulating an electrical component. The mold includes an encapsulation chamber and an air inlet. The encapsulation chamber is defined by a housing, an open top, and a solid bottom. The housing includes a solid outer wall, a permeable inner wall, and an air chamber between the solid outer wall and the inner wall. The air inlet is configured to introduce a gas into the air chamber. The encapsulation chamber is sized and shaped to receive the electrical component while leaving a gap for the introduction of encapsulant around the electrical component. The encapsulant may be silicone rubber. To remove an encapsulated electrical component, pressurized air may be introduced through the air inlet into the air chamber, passing through the permeable inner wall, separating the outer surface of the encapsulant from the housing, and allowing the combination casting to be removed from the mold.

Abstract: Provided herein are devices and methods used to produce tattoo biosensors that are based on spatially controlled intracutaneous gene delivery of optical reporters driven by specific transcription factor pathways for a given cytokine or other analyte. The biosensors can be specific to a given analyte, or more generically represent the convergence of several cytokines into commonly shared intracellular transcription factor pathways. These biosensors can be delivered as an array in order to monitor multiple cytokines. Biosensor redeployment can enable chronic monitoring from months to years. The tattooed biosensor array of the present invention includes endogenous reporter cells, naturally tuned to each patient's own biology and can be used to reliably measure the state of a patient in real-time.

Abstract: There is provided a diffuser for a turbine, comprising: a support configured to mount to a turbine housing; a diffuser body configured to receive fluid from an outlet of the turbine, the diffuser body defining a longitudinal axis and having a perimeter with a length measured in a plane normal to the longitudinal axis; and a bridge configured to connect the support to the diffuser body, wherein the connection between the bridge and the diffuser body is confined to a continuous portion of the perimeter of the diffuser body that is not more than around 50% of the total length of the perimeter of the diffuser body.

Abstract: The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Abstract: Use of porous carbon aerogel materials as capacitive deionization (CDI) electrodes to selectively remove scale forming divalent ions (e.g., Mg, Ca) from “hard” waters. A first electrode and/or a second electrode are made from activated carbon with graphite current collectors. A non-conductive, electrolyte permeable paper or polymer membrane separator is sandwiched between the first electrode and the second electrode.

Abstract: Provided herein are devices and methods used to produce tattoo biosensors that are based on spatially controlled intracutaneous gene delivery of optical reporters driven by specific transcription factor pathways for a given cytokine or other analyte. The biosensors can be specific to a given analyte, or more generically represent the convergence of several cytokines into commonly shared intracellular transcription factor pathways. These biosensors can be delivered as an array in order to monitor multiple cytokines. Biosensor redeployment can enable chronic monitoring from months to years. The tattooed biosensor array of the present invention includes endogenous reporter cells, naturally tuned to each patient's own biology and can be used to reliably measure the state of a patient in real-time.

Abstract: Methods, computer-readable media, systems and apparatuses for generation of a custom user interface for various categories of users and home maintenance, finance, and insurance monitoring are provided. The systems may receive data associated with a home, such as a plurality of systems and/or devices associated with the home. Based on the received information, the systems may generate a maintenance task list for the home including a plurality of maintenance tasks, finance task lists, and/or insurance task lists. Data related to maintenance performed on the home may be received and, based on the received maintenance data, a determination may be made as to whether one or more tasks on the maintenance task list have been completed.