Patents by Inventor Gabriel Saucy

Gabriel Saucy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use for bis-heterocyclic compounds and pharmaceutical compositions containing same
    Patent number: 5496950
    Abstract: A novel use for the class of biologically active bis-heterocyclic, e.g., bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, hamacanthins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: March 5, 1996
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Oliver J. McConnell, Gabriel Saucy, Robert Jacobs, Sarath P. Gunasekera
  • Use for bis-heterocyclic compounds and pharmaceutical compositions containing same
    Patent number: 5464835
    Abstract: A novel use for the class of biologically active bis-heterocyclic, e.g., bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, hamacanthins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: November 7, 1995
    Assignees: Harbor Branch Oceanographic Institution, Inc., University of California
    Inventors: Oliver J. McConnell, Gabriel Saucy, Robert Jacobs, Sarath P. Gunasekera
  • Use for topsentin compounds and pharmaceutical compositions containing same
    Patent number: 5290777
    Abstract: A novel use for the class of biologically active bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
    Type: Grant
    Filed: February 24, 1993
    Date of Patent: March 1, 1994
    Assignees: Regents of the Univ. of California, Harbor Branch Oceanographic Inst. Inc.
    Inventors: Oliver J. McConnell, Gabriel Saucy, Robert Jacobs
  • Synthesis of compounds with biological activity, and methods of use
    Patent number: 5166379
    Abstract: This invention relates to the methods for the synthesis and use of acetylenic carbinols and their analogs, having various immunomodulatory properties in vitro and in vivo.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: November 24, 1992
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Steve Coval, Gabriel Saucy, Richard D. Wood, Ranjit C. Desai, Geewananda P. Gunawardana, Ross E. Longley, Neal Burres
  • Synthesis of vitamin E and quinone intermediates
    Patent number: 4310465
    Abstract: A synthesis of Vitamin E has the condensation of 2,4-pentanediene and 1,2-epoxy-2,6,10,14-tetramethylpentadecane including intermediates in this synthesis which uses base catalyzed condensations of aliphatic compounds to construct the Vitamin E molecule from aliphatic precursors.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: January 12, 1982
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Gary L. Olson, Gabriel Saucy
  • Synthesis of 2,6,10-trimethyl-undecan-1-ol
    Patent number: 4277610
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: July 7, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Synthesis of vitamin E
    Patent number: 4243598
    Type: Grant
    Filed: September 10, 1979
    Date of Patent: January 6, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Gary L. Olson, Gabriel Saucy
  • Process for producing vitamin A
    Patent number: 4219506
    Abstract: A process for producing vitamin A esters, vitamin A aldehyde and vitamin A acid esters from esters of 3,7-dimethyl-9-(1-hydroxy-2,2,6-trimethylcyclohexyl)-nona-2,4,6-trien-8-yn -1-ol and 3,7-dimethyl-9-(1-hydroxy-2,2,6-trimethylcyclohexyl)-nona-2,4,6-trien-8-yn oic acid including intermediates in this process.
    Type: Grant
    Filed: January 17, 1979
    Date of Patent: August 26, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Gary L. Olson, Gabriel Saucy
  • Synthesis of optically active vitamin E
    Patent number: 4208331
    Abstract: Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
    Type: Grant
    Filed: January 29, 1979
    Date of Patent: June 17, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Synthesis of optically active vitamin E
    Patent number: 4208332
    Abstract: Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
    Type: Grant
    Filed: January 29, 1979
    Date of Patent: June 17, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Synthesis of Vitamin E
    Patent number: 4201726
    Abstract: A synthesis of Vitamin E has the condensation of 2,4-pentanediene and 1,2-epoxy-2,6,10,14-tetramethylpentadecane including intermediates in this synthesis which uses base catalyzed condensations of aliphatic compounds to construct the Vitamin E molecule from aliphatic precursors.
    Type: Grant
    Filed: September 11, 1978
    Date of Patent: May 6, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Gary L. Olson, Gabriel Saucy
  • Intermediates for steroid total synthesis process utilizing asymmetric induction
    Patent number: 4201869
    Abstract: A multi-step, stereospecific total synthesis of steroids is disclosed. The starting materials for this process are the relatively inexpensive and readily available m-alkoxy acetophenones. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly A-ring aromatic steroids. This process features an early optical resolution and a unique asymmetric induction which insures the correct stereochemistry of the final steroidal product.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: May 6, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Protected alcohols
    Patent number: 4191842
    Abstract: A synthesis of vitamin E in racemic or optically active forms from methacryolein or beta-hydroxyisobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: January 17, 1979
    Date of Patent: March 4, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • S-(+) 2,3,6-trimethyl-5-(2,2,4-trimethyl-1,3-dioxolane-4-ethyl)phenol
    Patent number: 4189612
    Abstract: Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
    Type: Grant
    Filed: January 29, 1979
    Date of Patent: February 19, 1980
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Synthesis of vitamin E
    Patent number: 4185154
    Abstract: A synthesis of Vitamin E has the condensation of 2,4-pentanediene and 1,2-epoxy-2,6,10,14-tetramethylpentadecane including intermediates in this synthesis which uses base catalyzed condensations of aliphatic compounds to construct the Vitamin E molecule from aliphatic precursors.
    Type: Grant
    Filed: September 11, 1978
    Date of Patent: January 22, 1980
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Gary L. Olson, Gabriel Saucy
  • Synthesis of optically active vitamin E
    Patent number: 4182719
    Abstract: Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
    Type: Grant
    Filed: January 29, 1979
    Date of Patent: January 8, 1980
    Assignee: Hoffman-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Unsaturated alcohols having an ether protected group
    Patent number: 4180682
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: December 25, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Ethers of 2,6,10-trimethyl-undecan-1-ols
    Patent number: 4172958
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: October 30, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Ethers of 2,6-dimethyl-octane-1,8-diols
    Patent number: 4169209
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: September 25, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Synthesis of 2,6,10-trimethyl-undecan-1-ol
    Patent number: 4163021
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: July 31, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy