Patents by Inventor Gabriel Saucy

Gabriel Saucy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asymmetric synthesis
    Patent number: 4160865
    Abstract: Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: July 10, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • Method of producing coloring agents
    Patent number: 4153615
    Abstract: A method of stereo-specifically synthesizing Zeaxanthin and alloxanthin, natural food coloring agents from 2,6,6-trimethyl-1,4-cyclohexanedione including intermediates in this synthesis.
    Type: Grant
    Filed: March 27, 1978
    Date of Patent: May 8, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Gabriel Saucy
  • Synthesis of vitamin E
    Patent number: 4151205
    Abstract: A synthesis of vitamin E in racemic or optically active forms from methacryolein or beta-hydroxyisobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: June 2, 1977
    Date of Patent: April 24, 1979
    Assignee: Hoffman-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Optically active amine salts
    Patent number: 4151360
    Abstract: Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: April 24, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • Synthesis of optically active vitamin E
    Patent number: 4151177
    Abstract: Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
    Type: Grant
    Filed: April 12, 1978
    Date of Patent: April 24, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Process for producing vitamin A
    Patent number: 4148829
    Abstract: A process for producing vitamin A esters, vitamin A aldehyde and vitamin A acid esters from esters of 3,7-dimethyl-9-(1-hydroxy-2,2,6-trimethylcyclohexyl)-nona-2,4,6-trien-8-yn -1-ol and 3,7-dimethyl-9-(1-hydroxy-2,2,6-trimethylcyclohexyL)-nona-2,4,6-trien-8-yn oic acid including intermediates in this process.
    Type: Grant
    Filed: January 31, 1977
    Date of Patent: April 10, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Gary L. Olson, Gabriel Saucy
  • Intermediate compounds for producing vitamin E
    Patent number: 4140723
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: February 20, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Process for producing vitamin E intermediate compounds
    Patent number: 4140702
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta. -hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: February 20, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Synthesis of optically active vitamin E
    Patent number: 4113740
    Abstract: Synthesis of optically active vitamin E from 2-methyl-5-oxotetrahydro-2-furoic acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 17, 1977
    Date of Patent: September 12, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Silicon ester of carboxylic acid
    Patent number: 4111961
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: September 5, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Tetramethyl chromanyl pentane derivatives
    Patent number: 4110346
    Abstract: Derivatives of 5[2,5,7,8-tetramethyl-chromanyl]-pentane which are intermediates for Vitamin E.
    Type: Grant
    Filed: December 8, 1976
    Date of Patent: August 29, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • Synthesis of optically active carboxylic acid esters
    Patent number: 4107183
    Abstract: A synthesis of 2,6,10-trimethyl-undecan-1-ol, an intermediate for producing vitamin E, from methacrolein, crotonaldehyde, .beta.-hydroxy-isobutyric acid including intermediates in this synthesis.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: August 15, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor
    Patent number: 4105676
    Abstract: A multi-step, stereospecific total synthesis of steroids utilizing intermediates having a cyanoalkyl A-ring precursor is disclosed. The initial starting materials for this process are the relatively inexpensive and commercially available reagents .gamma.-butyrolactone and sodium cyanide. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly 19-norsteroids. It is a feature of this process that conditions employed during the multiple step synthesis are selected so as to retain the normally labile nitrile group even during hydrogenation and hydrolysis steps. In this manner, it is possible to employ the nitrile group as an A-ring precursor without resorting to protective groups as was heretofore found necessary in previous steroid total synthesis processes.
    Type: Grant
    Filed: May 10, 1977
    Date of Patent: August 8, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Michael Rosenberger, Gabriel Saucy
  • Optically active esters and amides
    Patent number: 4102909
    Abstract: Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: July 25, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • Steroid total synthesis process utilizing asymmetric induction
    Patent number: 4102925
    Abstract: A multi-step, stereospecific total synthesis of steroids is disclosed. The starting materials for this process are the relatively inexpensive and readily available m-alkoxy acetophenones. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly A-ring aromatic steroids. This process features an early optical resolution and a unique asymmetric induction which insures the correct stereochemistry of the final steroidal product.
    Type: Grant
    Filed: December 22, 1976
    Date of Patent: July 25, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Noal Cohen, Gabriel Saucy
  • Claisen intermediates
    Patent number: 4100175
    Abstract: A total asymmetric synthesis for producing optically active vitamin E, from 2,5,7,8-tetramethylchroman-2-acetaldehyde including intermediates in this synthesis.
    Type: Grant
    Filed: March 15, 1977
    Date of Patent: July 11, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • Tetramethyl-benzyloxy chromans
    Patent number: 4097495
    Abstract: A total asymmetric synthesis for producing optically active vitamin E, from 2,5,7,8-tetramethylchroman-2-acetaldehyde including intermediates in this synthesis.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: June 27, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • 6(6-Substituted-2,5,7,8-tetramethyl-2-chromanyl)-3-methyl-4-hexenoic acid derivatives
    Patent number: 4094885
    Abstract: A total asymmetric synthesis for producing optically active vitamin E, from 2,5,7,8-tetramethylchroman-2-acetaldehyde including intermediates in this synthesis.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: June 13, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • Process for preparing optically active esters
    Patent number: 4094892
    Abstract: A symmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: June 13, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • 6(6-Substituted-2,5,7,8-tetramethyl-2-chromanyl)-3-methyl hexanol derivatives
    Patent number: 4093632
    Abstract: A total asymmetric synthesis for producing optically active vitamin E, from 2,5,7,8-tetramethylchroman-2-acetaldehyde including intermediates in this synthesis.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: June 6, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy