Patents by Inventor Gang Bao

Gang Bao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240190724
    Abstract: A bidirectional flow pulse-based water body phosphorus removal apparatus and a method, and an organic nutrient soil. The water body phosphorus removal apparatus includes: a prefiltration unit, a bidirectional flow phosphorus removal filtration pool, a bidirectional water collection and distribution system, a filtration pool stratified gas pulse system, a water production tank and a control system. A filtration layer filled with a phosphorus removal filtration material is provided in the bidirectional flow phosphorus removal filtration pool.
    Type: Application
    Filed: November 25, 2021
    Publication date: June 13, 2024
    Inventors: Kuixiao LI, Yulong SHI, Qi XU, Gang WANG, Jiawei WANG, Haipeng BAO, Guanglu LI, Fuliang MA
  • Publication number: 20240118401
    Abstract: A method for tracking zero-angle position shift of a moveable mirror used in a LiDAR system is provided. The method comprises obtaining a first dataset based on a first intensity map. The first intensity map is associated with internal reflection pulses of a frame scanned by the LiDAR system. The frame comprises a plurality of scan positions. The internal reflection pulses are formed by scattering or reflecting one or more transmission light pulses at positions internal to a housing of the LiDAR system. The first dataset is a calibration dataset comprising representative intensity values and corresponding positions in the frame. The method further comprises obtaining a second intensity map of another frame at a subsequent time and obtaining a second dataset based on the second intensity map. The method further comprises determining the zero-angle position shift of the moveable mirror based on the first dataset and the second dataset.
    Type: Application
    Filed: September 28, 2023
    Publication date: April 11, 2024
    Applicant: Innovusion, Inc.
    Inventors: Gang Zhou, Junwei Bao, Philip Andrew Wingard
  • Patent number: 11933850
    Abstract: A device for detecting a slot wedge, an air gap and a broken rotor bar is provided, where a sequential circuit generates double concurrent pulses; the sequential circuit is connected to driving power modules; the driving power modules are connected to front-end interface circuits; the front-end interface circuits convert the double concurrent pulses into corresponding magnetic-field pulses; the magnetic-field pulses are transmitted to power supply terminals on adjacent phases of stator windings through impedance matching pins and coupled at a corresponding coil, air gap and squirrel cage rotor to generate single groups of cyclic rotating magnetic potentials; single rotating magnetic potentials are sequentially generated in adjacent slots on each of the phases of the stator windings; rotating electric potentials in magnetic circuits with two symmetrical phases are magnetically coupled to form distributed coupling magnetic field reflected full-cycle waves for reflecting a difference of a corresponding slot wedg
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: March 19, 2024
    Assignee: HANGZHOU HENUOVA TECHNOLOGY CO., LTD.
    Inventors: Yuewu Zhang, Weixing Yang, Boyan Zhao, Jie Luo, Gang Du, Chao Wang, Han Gao, Liwei Qiu, Ming Xu, Jiamin Li, Yanxing Bao, Qianyi Zhang, Zuting Cao, Junliang Liu
  • Publication number: 20220264703
    Abstract: An microheater array system includes an integrated microheater array configured to generate a localized heat and having a plurality of pixels. Each pixel includes: an inductor; a stacked oscillator configured to generate a magnetic field at microwave frequencies with tunable intensity and frequency; and an electro-thermal loop. The microheater array system may further include a plurality of magnetic nanoparticles (MNPs).
    Type: Application
    Filed: February 14, 2022
    Publication date: August 18, 2022
    Inventors: Yingying Fan, Qingbo Zhang, Linlin Zhang, Gang Bao, Taiyun Chi
  • Patent number: 11315659
    Abstract: Methods and systems for searching genomes for potential nucleotide-guided nuclease off-target sites are provided. Also provided are methods of searching genomes for potential off-target deadCas9 binding sites. In some embodiments, the methods include ranking the potential off-target sites based on the number and location of mismatches, insertions, and/or deletions in the DNA, RNA, or DNA/RNA guide sequence relative to the genomic DNA sequence at a putative target site in the genome, allowing the selection of better target sites and/or experimental confirmation of off-target sites.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: April 26, 2022
    Assignee: GEORGIA TECH RESEARCH CORPORATION
    Inventors: Thomas James Cradick, Gang Bao, Peng Qiu
  • Patent number: 11184186
    Abstract: A method, an apparatus, and a computer program product for wireless communication are provided. The apparatus may be a UE. The UE determines whether the UE is located within a sub-region of an MBSFN area based on one or more parameters. The UE receives based on the determination a service over broadcast in the sub-region of the MBSFN area or over unicast outside the sub-region. In an aspect, the MBSFN area may be smaller than a unicast area. In an aspect, adaptive retransmission with a group NACK approach may be used to improve an SNR and reliability.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: November 23, 2021
    Assignee: QUALCOMM Incorporated
    Inventors: Xipeng Zhu, Jun Wang, Xiaoxia Zhang, Gang Bao
  • Patent number: 11120889
    Abstract: Endonucleases play an essential role in genetic engineering and molecular biology. A major barrier to the clinical adoption of nucleases and engineered nucleases remain the overall lack of specificity and activity. Off-site cleavage, cleavage at loci other than the target loci, typically occurs resulting in mutations, unexpected gene-knockouts, or translocations. Provided herein are systems and methods for identifying the off-site cleavage loci and predicting the activity of engineered endonucleases for a given genome. It is expected that these tools and methods will be useful for designing nucleases and other related DNA binding domains (e.g. TAL effectors) for genomic therapy and engineering.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 14, 2021
    Assignee: GEORGIA TECH RESEARCH CORPORATION
    Inventors: Eli Fine, Thomas J. Cradick, Yanni Lin, Gang Bao
  • Publication number: 20210263024
    Abstract: A novel fluorophore based on an acid soluble reagent that is a lanthanide metal ion nanoparticle that is passivated and/or coated for water dispersion and to minimize nonspecific binding, and assays for same
    Type: Application
    Filed: July 19, 2019
    Publication date: August 26, 2021
    Inventors: Xiaoyan Robert BAO, Gang BAO, Sheng Tong
  • Publication number: 20200058373
    Abstract: Methods and systems for searching genomes for potential nucleotide-guided nuclease off-target sites are provided. Also provided are methods of searching genomes for potential off-target deadCas9 binding sites. In some embodiments, the methods include ranking the potential off-target sites based on the number and location of mismatches, insertions, and/or deletions in the DNA, RNA, or DNA/RNA guide sequence relative to the genomic DNA sequence at a putative target site in the genome, allowing the selection of better target sites and/or experimental confirmation of off-target sites.
    Type: Application
    Filed: October 7, 2019
    Publication date: February 20, 2020
    Inventors: Thomas James Cradick, Gang Bao, Peng Qiu
  • Publication number: 20200036542
    Abstract: A method, an apparatus, and a computer program product for wireless communication are provided. The apparatus may be a UE. The UE determines whether the UE is located within a sub-region of an MBSFN area based on one or more parameters. The UE receives based on the determination a service over broadcast in the sub-region of the MBSFN area or over unicast outside the sub-region. In an aspect, the MBSFN area may be smaller than a unicast area. In an aspect, adaptive retransmission with a group NACK approach may be used to improve an SNR and reliability.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Inventors: Xipeng ZHU, Jun Wang, Xiaoxia Zhang, Gang Bao
  • Patent number: 10530595
    Abstract: A method, an apparatus, and a computer program product for wireless communication are provided. The apparatus may be a UE. The UE determines whether the UE is located within a sub-region of an MBSFN area based on one or more parameters. The UE receives based on the determination a service over broadcast in the sub-region of the MBSFN area or over unicast outside the sub-region. In an aspect, the MBSFN area may be smaller than a unicast area. In an aspect, adaptive retransmission with a group NACK approach may be used to improve an SNR and reliability.
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: January 7, 2020
    Assignee: QUALCOMM Incorporated
    Inventors: Xipeng Zhu, Jun Wang, Xiaoxia Zhang, Gang Bao
  • Publication number: 20190295689
    Abstract: Methods and systems for searching genomes for potential CRISPR off-target sites are provided. In preferred embodiments, the methods include identifying possible on- and off-target cleavage sites and /or ranking the potential off-target sites based on the number and location of mismatches, insertions, and/or deletions in the gRNA guide sequence relative to the genomic DNA sequence at a putative target site in the genome. These methods allow for the selection of better target sites and/or experimental confirmation of off-target sites and are an improvement over partial search mechanisms that fail to locate every possible target site.
    Type: Application
    Filed: May 13, 2019
    Publication date: September 26, 2019
    Inventors: Thomas James Cradick, Gang Bao, Peng Qiu
  • Patent number: 10354746
    Abstract: Methods and systems for searching genomes for potential CRISPR off-target sites are provided. In preferred embodiments, the methods include identifying possible on- and off-target cleavage sites and/or ranking the potential off-target sites based on the number and location of mismatches, insertions, and/or deletions in the gRNA guide sequence relative to the genomic DNA sequence at a putative target site in the genome. These methods allow for the selection of better target sites and/or experimental confirmation of off-target sites and are an improvement over partial search mechanisms that fail to locate every possible target site.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: July 16, 2019
    Assignee: Georgia Tech Research Corporation
    Inventors: Thomas James Cradick, Gang Bao, Peng Qiu
  • Patent number: 10286073
    Abstract: This disclosure describes a composition and method of magnetic nanoparticles (MNP) that are bound to a baculovirus (BV). The MNP-BV can be systemically administered to a patient, and a strong magnetic field applied to the target tissue, thus allowing uptake and expression only in the target tissue. Off-target effects are not seen because the MNP-BC is inactivated by the complement system outside of the magnetic field.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: May 14, 2019
    Assignee: ILISA TECH, INC.
    Inventors: Haibao Zhu, Sheng Tong, Gang Bao
  • Patent number: 9994823
    Abstract: This disclosure is in the area of research and therapeutics. In certain embodiments, it provides methods to assist in the purification of cell mixtures, e.g., cardiomyocytes, using molecular beacons targeting cell-type specific RNA, e.g. mRNA.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: June 12, 2018
    Assignees: Emory University, Georgia Tech Research Corporation
    Inventors: Young Sup Yoon, Gang Bao, Kiwon Ban, Brian Wile
  • Publication number: 20180128821
    Abstract: A new signal amplification method exploiting the dense atom packing in metallic nanocrystals has been developed for detecting target substances. By dissolving nanocrystals to individual ions that are stoichiometrically converted to chromophores and quantified photometrically, extremely high signal amplification can be achieved. Signal amplification is fully determined by the total number of atoms in the nanocrystals bound to a single target molecule. The disclosed nanocrystal amplification method can be implemented with a rich selection of metal/metal oxide nanocrystals and metal-reactive chromogenic substrates.
    Type: Application
    Filed: November 17, 2017
    Publication date: May 10, 2018
    Inventors: Gang Bao, Sheng Tong
  • Patent number: 9915651
    Abstract: A new signal amplification method exploiting the dense atom packing in metallic nanocrystals has been developed for detecting target substances. By dissolving nanocrystals to individual ions that are stoichiometrically converted to chromophores and quantified photometrically, extremely high signal amplification can be achieved. Signal amplification is fully determined by the total number of atoms in the nanocrystals bound to a single target molecule. The disclosed nanocrystal amplification method can be implemented with a rich selection of metal/metal oxide nanocrystals and metal-reactive chromogenic substrates. The chromogenic reactions can be either solution-based or surface-based and performed in aqueous or organic phase, supporting a variety of assay formats.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: March 13, 2018
    Inventors: Gang Bao, Sheng Tong
  • Publication number: 20180030438
    Abstract: The present application provides materials and methods for treating hemoglobinopathies. More specifically, the application provides methods for producing progenitor cells that are genetically modified via genome editing to increase the production of fetal hemoglobin (HbF), as well as modified progenitor cells (including, for example, CD34+ human hematopoietic stem cells) producing increased levels of HbF, and methods of using such cells for treating hemoglobinopathies such as sickle cell anemia and ?-thalassemia.
    Type: Application
    Filed: February 23, 2016
    Publication date: February 1, 2018
    Inventors: Matthew Hebden Porteus, Thomas James Cradick, Gang Bao, Ciaran M. Lee
  • Patent number: 9820259
    Abstract: Techniques are provided for smooth transition between broadcast/multicast transmission and unicast transmission. A method for managing unicast and multicast services switching in a multi-band/multi-frequency wireless communications system (WCS) capable of both unicast and multicast signaling includes determining whether an aggregate demand for a content provided via dedicated unicast transmissions exceeds a threshold. The method includes switching transmission of the content from the dedicated unicast transmissions on one frequency to a multicast transmission on a second or more frequencies in response to determining that the aggregate demand exceeds the threshold.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: November 14, 2017
    Assignee: QUALCOMM Incorporated
    Inventors: Jun Wang, George Cherian, Nagaraju Naik, Xiaoxia Zhang, Edward Robert Hall, Arungundram Chandrasekaran Mahendran, Gordon Kent Walker, Charles N. Lo, Carlos Marcelo Dias Pazos, Kuo-Chun Lee, Jack Shyh-Hurng Shauh, Gang Bao
  • Publication number: 20170239370
    Abstract: This disclosure describes a composition and method of magenitic nanoparticles (MNP) that are bound to a baculovirus (BV). The MNP-BV can be systemically administered to a patient, and a strong magnetic field applied to the target btissue, thus allowing uptake and expression only in the target tissue. Off-target effects are not seen because the MNP-BC is inactivated by the complement system outside of the magnetic field.
    Type: Application
    Filed: February 23, 2017
    Publication date: August 24, 2017
    Inventors: Haibao Zhu, Sheng TONG, Gang BAO