Abstract: An ultrasonic imaging method, including: during movement of a first ultrasonic transducer, receiving, over a period of time, an ultrasonic echo signal from tissue to be imaged; generating a first ultrasonic image set on the basis of the ultrasonic echo signals, the first ultrasonic image set including a plurality of ultrasonic images; identifying outer contours of a structure of interest in the plurality of ultrasonic images; and overlapping the outer contours of the structure of interest in the plurality of ultrasonic images to acquire a reconstructed image. Further provided in the present application are an ultrasonic imaging system and a non-transitory computer-readable medium.

Abstract: The present disclosure provides a PCR plate sealing film with good sealing effect, and relates to the technical field of experimental supplies, wherein the PCR plate sealing film comprises a supporting main plate and soft sealing films; L-shaped expansion rods are fixedly mounted on one end surface of the supporting main plate respectively; lateral-position limiting bars are fixedly mounted at lower ends of the two L-shaped expansion rods; a plurality of sealing bulges are integrally arranged on lower surfaces of the soft sealing films respectively; and the soft sealing films are located below the supporting main plate. The PCR plate sealing film provided by the present disclosure is fixed by a fixing component, to prevent the soft sealing films from moving up and down after being mounted.

Abstract: The present disclosure provides a highly practical cryovial, which relates to the technical field of the cryovial. The cryovial comprises an inner tube, a transparent outer tube, a limit snap ring, a liquid control mechanism arranged inside the inner tube, a protection mechanism arranged on the transparent outer tube, and a sealed liquid taking mechanism arranged on the inner tube, wherein the liquid control mechanism comprises a push rod and a piston block which is movably connected with the inner tube, first spiral holes of the same size are formed at the corresponding positions of the bottom ends of the inner tube and the transparent outer tube, and the push rod is movably connected with the two first spiral holes respectively.

Abstract: The present disclosure provides PROTAC compounds represented by Formula (A): D-L-DSM (A), or an enantiomer, a diastereoisomer, and/or a pharmaceutically acceptable salt of any one of the foregoing, wherein: DSM is a degradation signaling compound {e.g., an E3 ubiquitin ligase recruitment ligand, such as a CRBN ligand or a VHL ligand) covalently attached to a linker L; L is a linker that covalently attaches DSM to D; and D is a Bcl-xL inhibitor compound of Formula (I) or Formula (II) covalently attached to the linker L: (I); (II) wherein the definitions for the variables are described herein. Also provided are pharmaceutical compositions comprising the PROTAC compounds of the present disclosure and methods of use and methods of making thereof.

Abstract: The present disclosure provides a highly sealed PCR single tube, which relates to the technical field of the PCR single tube. The PCR single tube comprises a sealing tube, wherein the sealing tube is movably placed inside a storage box, four limited posts are fixedly connected on an upper surface of the storage box, a box cover is movably connected at upper ends of the limited posts, and an auxiliary component is fixedly installed inside the box cover. The sealing tube comprises a stud that is movably connected with a screw tube, four movable blocks are movably installed inside a lower side of the screw tube, and a second hose is fixedly connected outside the screw tube. The sealing tube comprises the stud that is movably connected with the screw tube, so that the stud could move up and down through rotation.

Abstract: A pressure compensation device with an accumulator group for controlled pressure drilling includes an electrical flat valve, a check valve, an accumulator group, a flanged pup joint and a support base. The electrical flat valve is connected to the check valve and is mounted on a top surface of the support base. The accumulator group mounted on the whole support base is a pre-storage pressure compensation device for controlled pressure drilling, and is located at a downstream position of the check valve. The liquid inlet end of the accumulator group is connected to the check valve, and the liquid discharge end is connected to the flanged pup joint.

Abstract: An information determining method includes: acquiring a feature vector of a target multimedia resource and feature vectors of multiple candidate multimedia resources; selecting, from the multiple candidate multimedia resources, a reference multimedia resource whose feature vector corresponds to the feature vector of the target multimedia resource; and selecting information corresponding to the target multimedia resource from multiple pieces of information about the reference multimedia resource according to the multiple pieces of information, and determining the selected information as information about the target multimedia resource.

Abstract: The disclosure relates to technology for pre-fetching data. An apparatus comprises a processor core, pre-fetch logic, and a memory hierarchy. The pre-fetch logic is configured to generate cache pre-fetch requests for a program instruction identified by a program counter. The pre-fetch logic is configured to track one or more statistics with respect to the cache pre-fetch requests. The pre-fetch logic is configured to link the one or more statistics with the program counter. The pre-fetch logic is configured to determine a degree of the cache pre-fetch requests for the program instruction based on the one or more statistics. The memory hierarchy comprises main memory and a hierarchy of caches. The memory hierarchy further comprises a memory controller configured to pre-fetch memory blocks identified in the cache pre-fetch requests from a current level in the memory hierarchy into a higher level of the memory hierarchy.

Abstract: An optical film layer and a manufacturing method thereof, a polarizer, and a display panel are provided. The optical film layer includes a base layer and a group of particle layers arranged in the base layer. The group of particle layers includes multiple particle layers, and refractive indices of the multiple particle layers gradually decrease in a direction from a first side of the optical film layer to a second side of the optical film layer.

Abstract: The present disclosure discloses a wall switch panel and a light fitting. The wall switch panel includes a touch panel, a micro-control module, and a wireless module. The touch panel has a first communication interface; the micro-control module has a second communication interface and a third communication interface, and the micro-control module is electrically connected with the first communication interface through the second communication interface; the wireless module has a fourth communication interface and is electrically connected with the third communication interface through the fourth communication interface.

Abstract: This invention provides a system and method that performs 3D imaging of a complex object, where image data is likely lost. Available 3D image data, in combination with an absence/loss of image data, allows computation of x, y and z dimensions. Absence/loss of data is assumed to be just another type of image data, and represents the presence of something that has prevented accurate data from being generated in the subject image. Segments of data can be connected to areas of absent data and generate a maximum bounding box. The shadow that this object generates can be represented as negative or missing data, but is not representative of the physical object. The height from the positive data, the object shadow size based on that height, the location in the FOV, and the ray angles that generate the images, are estimated and the object shadow size is removed from the result.

Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.

Abstract: The present invention belongs to the field of pharmaceutical manufacturing technology. The present invention provides a pharmaceutical composition of a conjugate and a preparation method thereof. The pharmaceutical composition is preferably administered by injection. The docetaxel conjugate has a structural formula as shown in the following formula: (I).

Abstract: Aspects described herein include devices and methods for phase tracking and correction using sampling. One aspect includes a wireless communication apparatus having an analog 1-bit sampler configured to sample a phase locked loop (PLL) output signal using a PLL reference clock to generate 1-bit samples and a digital phase computation and control circuit configured to receive the 1-bit samples from the analog 1-bit sampler and apply phase corrections to the PLL based on a phase error derived from the 1-bit samples.

Abstract: The present disclosure provides a method for improving a conductivity and a blue light filtering efficiency of a transparent conducting oxide (TCO). The method includes the following steps: placing an indium oxide-based transparent conducting material (TCM) as a sample into a sample chamber of a high-pressure apparatus, and conducting a room-temperature high-pressure treatment, where the room-temperature high-pressure treatment refers to compressing the sample to a target pressure of 51 GPa from ambient pressure at room temperature and holding the target pressure for 5 min, and then conducting decompression to the ambient pressure. The conductivity is detected during the compression and the decompression, and the blue light filtering efficiency is detected separately before and after the room-temperature high-pressure treatment.

Abstract: A field programmable gate array (FPGA) including a configurable interconnect fabric connecting a plurality of logic blocks, the configurable interconnect fabric and the logic blocks being configured to implement a data masking circuit configured to: receive input data including data values at a plurality of indices of the input data; select between a data value of the data values and an alternative value using a masking multiplexer to generate masked data, the masking multiplexer being controlled by a mask value of a plurality of mask values at indices corresponding to the indices of the input data; and output the masked data. In some examples, the configurable interconnect fabric and the logic blocks are further configured to implement a mask generation circuit configured to generate the mask values. In some examples, the mask values are received from external memory.

Abstract: Described herein is a method for preparing acesulfame potassium, comprising: pressing an acetoacetamide-N-sulfonic acid triethylamine salt solution and a cyclizing agent solution into a Venturireactor via different inlets, mixing same at a mixing section and a diffusion section of the Venturireactor, and then injecting the obtained mixture into a flow reactor, wherein the cyclizing agent solution is formed by dissolving sulfur trioxide in a first organic solvent; subjecting the mixture passing through the flow reactor to a sulfonation cyclization reaction under the action of a supported solid base heterogeneous catalyst preset in the flow reactor, and entering the obtained sulfonated cyclized product into a hydrolysis reactor; subjecting the sulfonated cyclized product and a hydrolysis agent preset in the hydrolysis reactor to a hydrolysis reaction to obtain a hydrolysis product solution; and adding potassium hydroxide into an organic phase of the hydrolysate solution for a salt-forming reaction to obtain the

Abstract: Described herein is a method for preparing acesulfame potassium, comprising: adding triethylamine to a sulfamic acid solution, and carrying out an amination reaction to produce a sulfamic acid ammonium salt solution; adding diketene to the obtained sulfamic acid ammonium salt solution, and under the action of a solid superacid catalyst, carrying out an acylation reaction to obtain an intermediate solution; dissolving sulfur trioxide in a solvent to form a cyclizing agent solution; adding the cyclizing agent solution to the intermediate solution, and carrying out a sulfonation cyclization reaction to obtain a cyclized product solution; adding a hydrolysis agent to the cyclized product solution, and carrying out a hydrolysis reaction to obtain a hydrolysis product solution; and adding a potassium hydroxide solution to the organic phase of the hydrolysis product solution to obtain acesulfame potassium.