Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.

Abstract: Smile treatment planning systems and methods are described herein. One method for adjusting an image of a smile may generally comprise receiving a three-dimensional (3D) digital model of a dental arch of a patient, receiving a digital facial image of the patient which includes an image of one or more teeth of the patient when smiling, registering the 3D digital model to the one or more teeth of the patient from the digital facial image, correcting the 3D digital model for scale and distortion to create a corrected 3D digital model, and overlaying the corrected 3D digital model onto the digital facial image.

Abstract: A method includes forming a first and a second dummy gate stack crossing over a semiconductor region, forming an ILD to embed the first and the second dummy gate stacks therein, replacing the first and the second dummy gate stacks with a first and a second replacement gate stack, respectively, performing a first etching process to form a first opening. A portion of the first replacement gate stack and a portion of the second replacement gate stack are removed. The method further includes filling the first opening to form a dielectric isolation region, performing a second etching process to form a second opening, with the ILD being etched, and the dielectric isolation region being exposed to the second opening, forming a contact spacer in the second opening, and filling a contact plug in the second opening. The contact plug is between opposite portions of the contact spacer.

Abstract: Embodiments of this application provide a data sending method, an apparatus, a device, and a readable storage medium. A server determines a first transmission point from a coordinated set, and determines a first downlink sending weight of the first transmission point. Then, the server determines a second downlink sending weight of a second transmission point based on the first downlink sending weight, and sends the second downlink sending weight to the second transmission point. When sending a data stream to an electronic device, the second transmission point determines a downlink sending weight corresponding to the data stream from a matrix, weights the data stream, and sends the weighted data stream to the electronic device.

Abstract: A sensorless commutation error compensation system for a brushless motor, comprises: a brushless motor (200) and a commutation logic module circuit (100). The commutation logic module circuit (100) is connected to three virtual Hall signal output ends of the brushless motor (200), and used for receiving three virtual Hall signals output by the brushless motor (200), obtaining three error compensation angle signals on the basis of the three virtual Hall signals, respectively superimposing the three error compensation angle signals and the three virtual Hall signals to form superposition results, and controlling the brushless motor (200) to adjust commutation timing on the basis of the superposition results, so as to achieve commutation error compensation.

Abstract: Provided are a roller assembly, a battery cell manufacturing device, and an adjustment method of a roller, which relates to the field of battery manufacturing technology. The roller assembly includes a holder, a roller, and a first adjusting member. The roller is rotatably mounted on the holder. The first adjusting member is rotatably mounted on the holder, and one end of the roller is rotatably connected to the first adjusting member. A rotation axis of the roller does not coincide with a rotation axis of the first adjusting member. One end of the roller is rotatably mounted on the holder through the first adjusting member. The rotation axis of the first adjusting member does not coincide with the rotation axis of the roller, and therefore, rotation of the first adjusting member is capable of driving a corresponding end of the roller to rotate, thereby adjusting an extension direction of the roller.

Abstract: An integrated semiconductor device is provided. The integrated semiconductor device includes a first semiconductor structure having a first IC, and a second semiconductor structure stacked above the first semiconductor structure and having a second IC. The second semiconductor structure has a first surface facing the first semiconductor structure and a second surface facing away from the first semiconductor structure. The integrated semiconductor device also includes a thermal dissipation structure having a first portion partially through the first IC and a second portion fully through the second semiconductor structure and exposed at the second surface of the second semiconductor structure. The second portion may be outside of the second IC.

Abstract: A method includes forming a first and a second dummy gate stack crossing over a semiconductor region, forming an ILD to embed the first and the second dummy gate stacks therein, replacing the first and the second dummy gate stacks with a first and a second replacement gate stack, respectively, performing a first etching process to form a first opening. A portion of the first replacement gate stack and a portion of the second replacement gate stack are removed. The method further includes filling the first opening to form a dielectric isolation region, performing a second etching process to form a second opening, with the ILD being etched, and the dielectric isolation region being exposed to the second opening, forming a contact spacer in the second opening, and filling a contact plug in the second opening. The contact plug is between opposite portions of the contact spacer.

Abstract: The present invention belongs to the technical field of liquid crystal materials, and in particular relates to a liquid crystal composition with good frequency dependence and a liquid crystal display element or liquid crystal display containing the liquid crystal composition. The liquid crystal composition of the present invention comprises a compound represented by Formula I, a compound represented by Formula II and a compound represented by Formula III, wherein the mass percentage content of the compound represented by Formula I is not less than 30%. The liquid crystal composition provided by the present invention has an appropriate optical anisotropy, an appropriate dielectric anisotropy, especially a relatively low rotational viscosity, a good low-temperature mutual solubility and a good reliability, especially good frequency dependence.

Abstract: The present invention belongs to the technical field of liquid crystal materials, and in particular relates to a negative liquid crystal composition and a liquid crystal display element or liquid crystal display containing the liquid crystal composition. The present invention discloses a negative dielectric nematic liquid crystal composition, comprising a compound represented by Formula I, one or more compounds represented by Formula II, and one or more compounds represented by Formula III. The liquid crystal composition has a relatively low rotational viscosity (?1), a high clearing point (Cp), a good solubility and a high stability to heat and light (VHR) on the basis of maintaining an appropriate optical anisotropy (?n), and can be used for developing a liquid crystal display element or liquid crystal display with a low cell thickness, a wide temperature for display, and a fast response.

Abstract: Some implementations described herein include systems and techniques for fabricating a multi-dimension through silicon via structure in a three-dimensional integrated circuit device. The multi-dimension through silicon via structure includes a first columnar structure having a first width and a second columnar structure including a second width that is greater relative to the first width. The first columnar structure may include a low electrical capacitance and be configured for electrical signaling within the three-dimensional integrated circuit device. The second columnar structure may be configured to provide power to integrated circuitry of the three-dimensional integrated circuit device and also be configured to conduct heat through the three-dimensional integrated circuit device for thermal management of the three-dimensional integrated circuit device. Additionally, a pattern including the second columnar structure may be used for alignment purposes.

Abstract: An integrated circuit (IC) device includes a substrate. The IC device includes a multi-layer interconnect structure disposed over a first side of the substrate. The multi-layer interconnect structure includes a plurality of metal layers. The IC device includes a first portion of a through-substrate via (TSV) disposed over the first side of the substrate. The first portion of the TSV includes a plurality of conductive components belonging to the plurality of metal layers of the multi-layer interconnect structure. The IC device includes a second portion of the TSV that extends vertically through the substrate from the first side to a second side opposite the first side. The second portion of the TSV is electrically coupled to the first portion of the TSV.

Abstract: The present application relates to a substrate, an LED light source assembly and manufacturing methods therefor. The substrate includes a first substrate and a second substrate which are arranged in a stacked manner. Electrode soldering regions on the front side of the first substrate and corresponding first conductive regions on the back side of the first substrate are electrically connected; and second conductive regions on the front side of the second substrate and corresponding third conductive regions on the back side of the second substrate are electrically connected, where the corresponding first conductive regions and the corresponding second conductive regions are electrically connected.

Abstract: The present invention belongs to the technical field of liquid crystal materials, and in particular relates to a liquid crystal composition with good frequency dependence and a liquid crystal display element or liquid crystal display containing the liquid crystal composition. The liquid crystal composition of the present invention comprises a compound represented by Formula I, a compound represented by Formula II and a compound represented by Formula III, wherein the mass percentage content of the compound represented by Formula I is not less than 30%. The liquid crystal composition provided by the present invention has an appropriate optical anisotropy, an appropriate dielectric anisotropy, especially a relatively low rotational viscosity, a good low-temperature mutual solubility and a good reliability, especially good frequency dependence.

Abstract: The present invention belongs to the technical field of liquid crystal materials, and in particular relates to a liquid crystal composition and a liquid crystal display element or liquid crystal display containing the liquid crystal composition. The liquid crystal composition of the present invention is characterized in that the liquid crystal composition comprises more than or equal to 30% of a compound represented by Formula I, and also comprises one or more compounds represented by Formula II and one or more compounds represented by Formula III. The liquid crystal composition of the present invention has a high refractive index, a high clearing point and also a low rotational viscosity, and is mainly used for the display of a projector with a relatively high working temperature and a low cell thickness.

Abstract: The present invention belongs to the technical field of liquid crystal materials, and in particular relates to a negative liquid crystal composition and a liquid crystal display element or liquid crystal display containing the liquid crystal composition. The present invention discloses a negative dielectric nematic liquid crystal composition, comprising a compound represented by Formula I, one or more compounds represented by Formula II, and one or more compounds represented by Formula III. The liquid crystal composition has a relatively low rotational viscosity (?1), a high clearing point (Cp), a good solubility and a high stability to heat and light (VHR) on the basis of maintaining an appropriate optical anisotropy (?n), and can be used for developing a liquid crystal display element or liquid crystal display with a low cell thickness, a wide temperature for display, and a fast response.

Abstract: A liquid crystal composition, a liquid crystal display element and a liquid crystal display comprising the liquid crystal composition belong to the field of liquid crystal display. The liquid crystal composition comprises a compound represented by formula I with a mass content of 1-10% as the first component, a compound represented by formula II with a mass content of 1-20% as the second component, more than two compounds represented by formula III as the third component, more than three compounds represented by formula IV as the fourth component, and one or more polymerizable compounds as the fifth component, the crystal composition has low rotational viscosity and low ?1/K33 on the basis of maintaining appropriate optical anisotropy. When applied to liquid crystal display elements or liquid crystal displays, the liquid crystal display has a fast response speed.

Abstract: A positive dielectric anisotropic liquid crystal composition includes one or more compounds of formula I and one or more compounds of formula II: wherein R1 represents cyclopropyl, cyclobutyl or cyclopentyl, R2, R3 and R4 are as defined in the specification, and a liquid crystal display device. The liquid crystal composition has positive dielectric properties, a high charge retention ratio, a low rotary viscosity, a fast response time, and especially a high transmittance, and is suitable for manufacturing a TFT-LCD with a high transmittance and a fast response.

Abstract: A liquid crystal composition, a liquid crystal display element and a liquid crystal display comprising the liquid crystal composition belong to the field of liquid crystal display. The liquid crystal composition of the present disclosure comprises a compound represented by formula I, a compound represented by formula II, one or more compounds represented by formula III, one or more compounds represented by formula IV and more than three compounds represented by formula V. The liquid crystal composition has low rotational viscosity ?1 and high stability to heat and light on the basis of maintaining appropriate optical anisotropy ?n, which can realize fast response of liquid crystal display.

Abstract: A dielectric negative liquid crystal composition, a liquid crystal display element and a liquid crystal display containing the liquid crystal composition belong to the field of liquid crystal display. The liquid crystal composition of the present disclosure includes a compound represented by formula I, a compound represented by formula II, two or more compounds represented by formula III and one or more compounds represented by formula IV. The liquid crystal composition of the present invention has high dielectric anisotropy, high elastic constant K, low rotational viscosity, can be used to develop large dielectric, fast response liquid crystal display elements or liquid crystal displays.