Patents by Inventor Gang Wu

Gang Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240067638
    Abstract: The present invention relates to imidazo[1,2-a]pyridine and [1,2,4]triazolo[1, 5-a]pyridine derivatives of formula (I) or a salt thereof. The present compounds are inhibitors of TLR9 and useful in treating preventing, or slowing fibrotic diseases, such as e.g. liver fibrosis, renal fibrosis, biliary fibrosis or pancreatic fibrosis, nonalcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), chronic kidney disease, diabetic kidney disease, primary sclerosing cholangitis (PSC) or primary biliary cirrhosis (PBC), or idiopathic pulmonary fibrosis (IPF).
    Type: Application
    Filed: August 18, 2021
    Publication date: February 29, 2024
    Inventors: David S. Yoon, Alicia Regueiro-Ren, Andrew P. Degnan, Gang WU
  • Patent number: 11911513
    Abstract: Disclosed are a controlled-release dosage form with an absorption window in the upper gastrointestinal tract and a preparation method therefor, wherein the controlled-release dosage form comprises a controlled-release platform and a retention platform. The controlled-release platform is a pharmaceutical composition comprising a tablet core and a coating membrane; and the retention platform holds the controlled-release platform in the oral cavity. The operation steps of the controlled-release dosage form are as follows: placing the controlled-release platform in the retention platform, and fixing the retention platform on matching teeth in the oral cavity; taking out the controlled-release dosage form after 4-24 hours and replacing same with a new controlled-release platform; and re-fixing the retention platform on the matching teeth in the oral cavity to achieve the sustained and stable release of drugs.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: February 27, 2024
    Assignee: SHANGHAI WD PHARMACEUTICAL CO., LTD
    Inventors: Liang Chang Dong, Xishan Chen, Jingmin Shi, Danyong Zhang, Gang Wu
  • Patent number: 11914235
    Abstract: Disclosed are a viewing angle adjustment film structure, a manufacturing method thereof, and a display device, including a base, an isotropic optical material layer, and a liquid crystal layer stacked in sequence. The isotropic optical material layer is provided with grooves, the liquid crystal layer fills the grooves, and light enters from the liquid crystal layer and then exits through the isotropic optical material layer. Director of liquid crystal molecules in the liquid crystal layer is changed according to an external applied voltage or a change of an electric field, so as to adjust a viewing angle of the light emitted from the isotropic optical material layer.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: February 27, 2024
    Assignee: TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Hu Dou, Ziping Wu, Gang Yu
  • Publication number: 20240059712
    Abstract: The disclosure relates to bifunctional KRAS-G12D-modulating compounds having the structure W-L-T, where W is a targeting group that binds specifically to KRAS-G12D protein, T is an E3-ligase binding group, and L is absent or is a bivalent linking group that connects W and T together via a covalent linkage. Compounds and pharmaceutical compositions thereof can promote degradation of the KRAS-G12D protein in a cell and are thus useful for treating, inhibiting, and preventing KRAS-G12D-associated diseases, disorders and conditions, including cancers.
    Type: Application
    Filed: September 13, 2023
    Publication date: February 22, 2024
    Inventors: Jiasheng LV, Xiang JI, Gang WU, Bin ZONG, Qiguo ZHANG, Yanpeng WU, Xiangyang LI, Yuhui CHEN, Yongyue CHEN, Chuanhao HUANG, Xingwu ZHU, Xiaolin HE, Yao LIU, Yuhua ZHANG, Jian GE, Tianlun ZHOU, Xiangsheng YE, Xianqi KONG, Dawei CHEN
  • Patent number: 11904400
    Abstract: This paper describes an invention involving an electrochemical discharge-enabled micro-grinding process for micro-components of silicon-based materials. The specific machining method is described below. A micro-grinding tool and an auxiliary electrode are respectively connected to the negative and positive electrodes of a pulsed DC power supply. When the current flows through the loop, an electrochemical hydrogen evolution reaction (HER) occurs at the micro-grinding tool in the grinding fluid, which generate multiple hydrogen bubbles. The bubbles coalesce into an insulating gas film and separate the micro-grinding tool from the grinding fluid; when the critical voltage is reached, the gas film is broken down and an electrochemical discharge occurs accompanied by discharge spark; under the action of the discharge spark, the surface material of the workpiece in the discharge-affected region is directly ablated to generate a heat-affected layer (HAL), namely, physical modification.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 20, 2024
    Assignee: Changsha University of Science and Technology
    Inventors: Cong Mao, Weidong Tang, Yuanqiang Luo, Yinghui Ren, Wei Li, Mingjun Zhang, Kun Tang, Gang Wu, Yongle Hu, Feng Shi, Ziyang Chen, Zhuo Wen
  • Publication number: 20240050199
    Abstract: Disclosed are a shell-shaped dental instrument and a shell-shaped dental appliance set including at least one shell-shaped dental instrument. The shell-shaped dental instrument includes a shell-shaped body having a plurality of tooth receiving cavities. The shell-shaped body includes a screen block, and the screen block includes a blocking portion disposed on a labial side and/or a buccal side of the shell-shaped body and being protruded in a direction away from teeth, and a contact portion connected with the blocking portion, where the blocking portion is configured to be in contact with labial muscle and/or buccal muscle during wearing of the shell-shaped dental instrument, such that force exerted by the labial muscle and/or the buccal muscle on the blocking portion is at least partially transmitted to gingiva through the contact portion.
    Type: Application
    Filed: October 27, 2023
    Publication date: February 15, 2024
    Inventors: Huimin ZHUANG, Xingxing WANG, Gang WU, Junfeng YAO
  • Publication number: 20240048183
    Abstract: A near field communication (NFC) reader detects whether NFC devices are passive NFC devices or active NFC devices. The NFC reader outputs an interrogation signal and a carrier signal. When the NFC reader receives a response signal from an NFC device responsive to the interrogation signal, the NFC reader adjusts the frequency of the carrier signal before the end of the response signal. The NFC reader determines whether the NFC device is a passive NFC device or an active NFC device based on characteristics of the remaining portion of the response signal.
    Type: Application
    Filed: December 22, 2020
    Publication date: February 8, 2024
    Applicant: STMICROELECTRONICS (CHINA) INVESTMENT CO., LTD.
    Inventors: Tianhao XIONG, Gang WU
  • Patent number: 11892101
    Abstract: Embodiments provide anti-frost heaving supports and methods for crude oil pipeline crossing permafrost region. The anti-frost heaving support includes a support frame. An arc-shaped frame is installed on a top of the support frame. Two sets of adjusting devices are disposed on the arc-shaped frame, each set of the adjusting devices includes a pushing device fixedly installed on the arc-shaped frame. In the anti-frost heaving support, a piston plate compresses air inside the sealing frame so that a compressional force of an elastic plate and a stressed plate on the pipeline increases. When the compressional force increases, the elastic plate deforms to make a moving rod to move towards to an interior of the sealing frame. When moving on a tilted surface of a tilting plate, the moving rod pushes the tilting plate to move. The tilting plate pushes the sealing plate to be opened to release the air inside the sealing frame, thereby reducing the compressive force exerted by the stressed plate on the pipeline.
    Type: Grant
    Filed: August 29, 2023
    Date of Patent: February 6, 2024
    Assignee: NORTHWEST INSTITUTE OF ECO-ENVIRONMENT AND RESOURCES, CAS
    Inventors: Yapeng Cao, Guoyu Li, Wei Ma, Dun Chen, Kai Gao, Gang Wu
  • Publication number: 20240023055
    Abstract: A positioning apparatus includes: a first positioning module configured to obtain location information of the positioning apparatus in real time; and an ultra-wide-band (UWB) positioning module configured to receive a positioning request message sent by a to-be-positioned tag, where the positioning request message includes identification information of the to-be-positioned tag. The UWB positioning module is further configured to determine, after receiving the positioning request message, whether the UWB positioning module is in a UWB base station mode. The UWB positioning module is further configured to perform, in the UWB base station mode, positioning measurement on the to-be-positioned tag based on the location information and the identification information.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 18, 2024
    Inventors: Yonggang Song, Gang Wu, Yalin Liu
  • Publication number: 20240016978
    Abstract: An efficient biphasic calcium phosphate coating method. A high-concentration (4.5×) supersaturated calcium phosphate solution (SCPS) is used for coating and a thicker continuous coating is formed on a titanium disc. The coating contains dicalcium phosphate dihydrate and hydroxyapatite. The coating has improved encapsulation efficiency of a protein FITC-BSA and releases less Ca2+ under an acidic condition. A more efficient coating with a high yield and a protein encapsulation efficiency can be obtained with a less SCPS solution volume and a shorter coating time, such that a cost is greatly reduced in clinical application and the coating is very expected to be used in an osteogenic implant material in the biomedical field.
    Type: Application
    Filed: April 1, 2021
    Publication date: January 18, 2024
    Inventors: Gang WU, Liyong WU, Yunyu LU
  • Publication number: 20240001346
    Abstract: A catalyst for continuous production of 1,1,1,3-tetrachloropropane through gas-solid reaction as well as a preparation method and use thereof are provided. The catalyst includes a zero-valent iron and phosphorus co-modified carbon material which includes a carbon material as a carrier, a zero-valent iron supported onto the carrier and serving as an active component, and a phosphate functional group formed on the surface of the carbon material. The preparation method includes: co-modifying a carbon material using a ferric salt and organic phosphorus to obtain the catalyst for continuous production of 1,1,1,3-tetrachloropropane through gas-solid reaction. The present application further provides a method for continuous production of 1,1,1,3-tetrachloropropane through gas-solid reaction.
    Type: Application
    Filed: December 24, 2021
    Publication date: January 4, 2024
    Applicants: NINGBO INSTITUTE OF MATERIALS TECHNOLOGY AND ENGINEERING, CHINESE ACADEMY OF SCIENCES, NINGBO JUHUA CHEMICAL & SCIENCE CO., LTD.
    Inventors: Yexin ZHANG, Qiang ZHOU, Jian ZHANG, Junliang ZHONG, Xiuxiu WANG, Jili DU, Hui CHEN, Chengjun MU, Jie YANG, Linbing XIA, Yong YANG, Gang WU
  • Publication number: 20230379507
    Abstract: Embodiments described herein provide methods and systems for facilitating actively-learned context modeling. In one embodiment, a subset of data is selected from a training dataset corresponding with an image to be compressed, the subset of data corresponding with a subset of data of pixels of the image. A context model is generated using the selected subset of data. The context model is generally in the form of a decision tree having a set of leaf nodes. Entropy values corresponding with each leaf node of the set of leaf nodes are determined. Each entropy value indicates an extent of diversity of context associated with the corresponding leaf node. Additional data from the training dataset is selected based on the entropy values corresponding with the leaf nodes. The updated subset of data is used to generate an updated context model for use in performing compression of the image.
    Type: Application
    Filed: May 20, 2022
    Publication date: November 23, 2023
    Inventors: Gang Wu, Yang Li, Stefano Petrangeli, Viswanathan Swaminathan, Haoliang Wang, Ryan A. Rossi, Zhao Song
  • Publication number: 20230368265
    Abstract: Embodiments provide systems, methods, and computer storage media for a Nonsymmetric Determinantal Point Process (NDPPs) for compatible set recommendations in a setting where data representing entities (e.g., items) arrives in a stream. A stream representing compatible sets of entities is received and used to update a latent representation of the entities and a compatibility distribution indicating likelihood of compatibility of subsets of the entities. The probability distribution is accessed in a single sequential pass to predict a compatible complete set of entities that completes an incomplete set of entities. The predicted complete compatible set is provided a recommendation for entities that complete the incomplete set of entities.
    Type: Application
    Filed: May 12, 2022
    Publication date: November 16, 2023
    Inventors: Ryan A. Rossi, Aravind Reddy Talla, Zhao Song, Anup Rao, Tung Mai, Nedim Lipka, Gang Wu, Anup Rao
  • Patent number: 11807542
    Abstract: A method for preparing urea ammonium nitrate solution from waste nitric acid after stripping tin from circuit board includes: causing the waste nitric acid after stripping tin and the ammonia water to undergo neutralizing and precipitating reaction through acid-base neutralization, filtering, thereby obtaining tin-containing filter mud and a primary filtrate; adding iron powders into to the primary filtrate to initiate copper-iron replacement reaction, filtering, thereby obtaining iron-containing coarse copper powders and a secondary filtrate; adding hydrogen peroxide to the secondary filtrate, filtering, thereby obtaining an iron-containing sludge and a tertiary filtrate; adding a heavy metal capturing agent to the tertiary filtrate, filtering, thereby obtaining a heavy metal sludge and an ammonium nitrate solution; measuring a concentration of the ammonium nitrate solution, adding urea and liquid fertilizer corrosion inhibitor to obtain a urea/ammonium nitrate dilute solution, evaporating and concentrating
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: November 7, 2023
    Assignee: SHENZHEN ENVIRONMENTAL TECHNOLOGY GROUP CO. LTD.
    Inventors: Wei-Hong Wang, Jian-Gang Wu, Chao-Lin Mao, Chun-Hua Liao, Chang-Ming Chen, Kuan-Wei Huang, Xue-Qiang Huang
  • Publication number: 20230338119
    Abstract: The orthodontic system includes shell-shaped dental appliances, where a dental appliance body is further provided with an eruption portion spaced apart from one or more teeth not grown to preset eruption parameters. As an orthodontic plan proceeds, the eruption portion on each of the shell-like dental appliances has a constant or basically constant column structure. The shell-like dental appliances have an effect of correcting irregularities of teeth. The eruption portion is configured to accommodate teeth not grown to the preset eruption parameters. A gap between the eruption portion and erupting teeth makes the dental appliance body reserve a space for tooth growth above the erupting tooth, such that the shell-like dental appliances cannot interfere with natural growth of teeth when being worn. In addition, the eruption portion with the constant or basically constant column structure is simpler to design and use and can serve as a standard attachment.
    Type: Application
    Filed: June 30, 2023
    Publication date: October 26, 2023
    Inventors: XINGXING WANG, GANG WU, JUNFENG YAO
  • Publication number: 20230321740
    Abstract: The invention provides an electrochemical discharge-assisted micro-grinding device for micro-components of brittle and hard materials. The device includes a micro-grinding tool, grinding fluid, a workpiece, an auxiliary electrode, a processing groove, and a pulsed DC power supply; the processing groove is filled with grinding fluid; the micro-grinding tool, the workpiece, and the auxiliary electrode are immersed in the grinding fluid; the micro-grinding tool is composed of a conductive grinding tool base, an electroplating layer, and insulated superabrasives. The micro-grinding tool is connected to the negative electrode of the pulsed DC power supply; the grinding fluid is composed of H2O2, Na2CO3, EDTA-Fe-Na, and deionized water; the workpiece material is brittle and hard; a large number of micro structures need to be produced on the surface of the workpiece.
    Type: Application
    Filed: April 29, 2022
    Publication date: October 12, 2023
    Inventors: Cong MAO, Ziyang CHEN, Yinghui REN, Wei LI, Yuanqiang LUO, Gang WU, Mingjun ZHANG, Kun TANG, Yongle HU, Feng SHI, Weidong TANG, Ci SONG
  • Patent number: 11783486
    Abstract: Generating images and videos depicting a human subject wearing textually defined attire is described. An image generation system receives a two-dimensional reference image depicting a person and a textual description describing target clothing in which the person is to be depicted as wearing. To maintain a personal identity of the person, the image generation system implements a generative model, trained using both discriminator loss and perceptual quality loss, which is configured to generate images from text. In some implementations, the image generation system is configured to train the generative model to output visually realistic images depicting the human subject in the target clothing. The image generation system is further configured to apply the trained generative model to process individual frames of a reference video depicting a person and output frames depicting the person wearing textually described target clothing.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: October 10, 2023
    Assignee: Adobe Inc.
    Inventors: Viswanathan Swaminathan, Gang Wu, Akshay Malhotra
  • Publication number: 20230294189
    Abstract: This paper describes an invention involving an electrochemical discharge-enabled micro-grinding process for micro-components of silicon-based materials. The specific machining method is described below. A micro-grinding tool and an auxiliary electrode are respectively connected to the negative and positive electrodes of a pulsed DC power supply. When the current flows through the loop, an electrochemical hydrogen evolution reaction (HER) occurs at the micro-grinding tool in the grinding fluid, which generate multiple hydrogen bubbles. The bubbles coalesce into an insulating gas film and separate the micro-grinding tool from the grinding fluid; when the critical voltage is reached, the gas film is broken down and an electrochemical discharge occurs accompanied by discharge spark; under the action of the discharge spark, the surface material of the workpiece in the discharge-affected region is directly ablated to generate a heat-affected layer (HAL), namely, physical modification.
    Type: Application
    Filed: April 29, 2022
    Publication date: September 21, 2023
    Inventors: Cong MAO, Weidong TANG, Yuanqiang LUO, Yinghui REN, Wei LI, Mingjun ZHANG, Kun TANG, Gang WU, Yongle HU, Feng SHI, Ziyang CHEN, Zhuo WEN
  • Patent number: D1016295
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: February 27, 2024
    Assignee: SHANGHAI SMARTEE DENTI-TECHNOLOGY CO., LTD.
    Inventors: Huimin Zhuang, Xingxing Wang, Gang Wu, Junfeng Yao
  • Patent number: D1016296
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: February 27, 2024
    Assignee: SHANGHAI SMARTEE DENTI-TECHNOLOGY CO., LTD.
    Inventors: Huimin Zhuang, Xingxing Wang, Gang Wu, Junfeng Yao