Patents by Inventor Gary Desir

Gary Desir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE PEPTIDES HAVING RENALASE AGONIST ACTIVITY
    Publication number: 20230190883
    Abstract: Disclosed are stable peptides that have renalase agonist activity and are useful for treating diseases such as AKI and AP, including those relating to SARS-CoV-2
    Type: Application
    Filed: May 28, 2021
    Publication date: June 22, 2023
    Inventors: Gary Desir, Arthur Felix, Wallace Dairman, Anthony Barrett, Barry Berkowitz
  • Anti-Renalase Antibodies for the Treatment and Prevention of Diseases and Disorders
    Publication number: 20220348684
    Abstract: The present invention relates to compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules may act as therapeutics.
    Type: Application
    Filed: December 27, 2018
    Publication date: November 3, 2022
    Inventors: Gary Desir, Bryce Nelson
  • Compositions and Methods to Regulate Renalase in the Treatment of Cancer
    Publication number: 20220281996
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Application
    Filed: May 9, 2022
    Publication date: September 8, 2022
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Compositions and methods to regulate Renalase in the treatment of cancer
    Patent number: 11370846
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: June 28, 2022
    Assignee: Yale University
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Compositions and Methods For Treating Cancer with Anti-Renalase antibodies and Anti-PD1 antibodies
    Publication number: 20210355235
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Application
    Filed: March 8, 2018
    Publication date: November 18, 2021
    Inventor: Gary Desir
  • Compositions and methods for treating and preventing pancreatitis, renal injury and cancer
    Patent number: 11124779
    Abstract: The present invention includes compositions and methods for detecting, treating and preventing renal and pancreatic diseases and disorders.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: September 21, 2021
    Assignee: Yale University
    Inventor: Gary Desir
  • Compositions and methods for detecting, treating and preventing diseases and disorders
    Patent number: 10941212
    Abstract: The invention described herein relates to the discovery that renalase, and fragments thereof, are useful for the treatment or prevention of cardiac and renal diseases or disorders. Thus, the invention relates to compositions comprising renalase, or fragments thereof, and methods for treating and preventing cardiac and renal disease or disorders.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: March 9, 2021
    Assignee: YALE UNIVERSITY
    Inventor: Gary Desir
  • Compositions and Methods to Regulate Renalase in the Treatment of Cancer
    Publication number: 20210024652
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Application
    Filed: April 14, 2020
    Publication date: January 28, 2021
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Methods for Measuring Renalase
    Publication number: 20200340031
    Abstract: The present invention relates to compositions and methods for binding and detecting or measuring renalase. In one embodiment, the renalase binding molecule measures renalase amount or activity. Thus, in diseases and conditions where a measurement of renalase is beneficial, such renalase binding molecules may act as diagnostics.
    Type: Application
    Filed: December 27, 2018
    Publication date: October 29, 2020
    Inventors: Gary Desir, Jeffrey Testani, Veena Rao
  • Antibody to Renalase
    Patent number: 10618975
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: April 14, 2020
    Assignee: YALE UNIVERSITY
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Compositions and Methods for Treating and Preventing Pancreatitis, Renal Injury and Cancer
    Publication number: 20190382736
    Abstract: The present invention includes compositions and methods for detecting, treating and preventing renal and pancreatic diseases and disorders.
    Type: Application
    Filed: June 27, 2019
    Publication date: December 19, 2019
    Inventor: Gary Desir
  • Compositions and Methods to Regulate Renalase in the Treatment of Cancer
    Publication number: 20190194355
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Application
    Filed: March 7, 2019
    Publication date: June 27, 2019
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Compositions to regulate renalase in the treatment of diseases and disorders
    Patent number: 10273311
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: April 30, 2019
    Assignee: YALE UNIVERSITY
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Compositions and Methods for Detecting, Treating and Preventing Diseases and Disorders
    Publication number: 20190031777
    Abstract: The invention described herein relates to the discovery that renalase, and fragments thereof, are useful for the treatment or prevention of cardiac and renal diseases or disorders. Thus, the invention relates to compositions comprising renalase, or fragments thereof, and methods for treating and preventing cardiac and renal disease or disorders.
    Type: Application
    Filed: August 21, 2018
    Publication date: January 31, 2019
    Inventor: Gary Desir
  • Compositions and methods for detecting, treating and preventing diseases and disorders
    Patent number: 10066025
    Abstract: The invention described herein relates to the discovery that renalase, and fragments thereof, are useful for the treatment or prevention of cardiac and renal diseases or disorders. Thus, the invention relates to compositions comprising renalase, or fragments thereof, and methods for treating and preventing cardiac and renal disease or disorders.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: September 4, 2018
    Assignee: YALE UNIVERSITY
    Inventor: Gary Desir
  • Compositions and Methods to Regulate Renalase in the Treatment of Diseases and Disorders
    Publication number: 20170226228
    Abstract: The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
    Type: Application
    Filed: June 26, 2015
    Publication date: August 10, 2017
    Inventors: Gary Desir, Abigail Hunt, Jessica O-Rear, Peter Flynn
  • Compositions and Methods for Treating and Preventing Pancreatitis, Renal Injury and Cancer
    Publication number: 20170107499
    Abstract: The present invention includes compositions and methods for detecting, treating and preventing renal and pancreatic diseases and disorders.
    Type: Application
    Filed: May 15, 2015
    Publication date: April 20, 2017
    Inventor: Gary Desir
  • Compositions and Methods for Detecting, Treating and Preventing Diseases and Disorders
    Publication number: 20150210774
    Abstract: The invention described herein relates to the discovery that renalase, and fragments thereof, are useful for the treatment or prevention of cardiac and renal diseases or disorders. Thus, the invention relates to compositions comprising renalase, or fragments thereof, and methods for treating and preventing cardiac and renal disease or disorders.
    Type: Application
    Filed: July 16, 2013
    Publication date: July 30, 2015
    Inventor: Gary Desir
  • DETECTION, ISOLATION AND USES OF RENALASE (MONOAMINE OXIDASE C)
    Publication number: 20130273023
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Application
    Filed: April 21, 2011
    Publication date: October 17, 2013
    Applicant: YALE UNIVERSITY
    Inventors: JIANCHAO XU, GARY DESIR
  • Detection, isolation and uses of renalase (monoamine oxidase C)
    Patent number: 7932067
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: April 26, 2011
    Assignee: Yale University
    Inventors: Jianchao Xu, Gary Desir