Patents by Inventor Gary Desir

Gary Desir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Detecting, Treating and Preventing Diseases and Disorders
    Publication number: 20150210774
    Abstract: The invention described herein relates to the discovery that renalase, and fragments thereof, are useful for the treatment or prevention of cardiac and renal diseases or disorders. Thus, the invention relates to compositions comprising renalase, or fragments thereof, and methods for treating and preventing cardiac and renal disease or disorders.
    Type: Application
    Filed: July 16, 2013
    Publication date: July 30, 2015
    Inventor: Gary Desir
  • DETECTION, ISOLATION AND USES OF RENALASE (MONOAMINE OXIDASE C)
    Publication number: 20130273023
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Application
    Filed: April 21, 2011
    Publication date: October 17, 2013
    Applicant: YALE UNIVERSITY
    Inventors: JIANCHAO XU, GARY DESIR
  • Detection, isolation and uses of renalase (monoamine oxidase C)
    Patent number: 7932067
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: April 26, 2011
    Assignee: Yale University
    Inventors: Jianchao Xu, Gary Desir
  • METHODS OF REGULATING RENALASE (MONOAMINE OXIDASE C)
    Publication number: 20110081421
    Abstract: The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action.
    Type: Application
    Filed: November 15, 2010
    Publication date: April 7, 2011
    Applicant: YALE UNIVERSITY
    Inventors: GARY DESIR, JIANCHAO XU
  • Methods of treatment with renalase (monoamine oxidase C)
    Patent number: 7858084
    Abstract: The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action.
    Type: Grant
    Filed: November 21, 2006
    Date of Patent: December 28, 2010
    Assignee: Yale University
    Inventors: Gary Desir, Jianchao Xu
  • DETECTION, ISOLATION AND USES OF RENALASE (MONOAMINE OXIDASE C)
    Publication number: 20100136651
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Application
    Filed: January 28, 2010
    Publication date: June 3, 2010
    Applicant: Yale University
    Inventors: Jianchao Xu, Gary Desir
  • Detection, isolation and uses of renalase (monoamine oxidase c)
    Patent number: 7700095
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: April 20, 2010
    Assignee: Yale University
    Inventors: Jianchao Xu, Gary Desir
  • Detection, Isolation and Uses Of Renalase (Monoamine Oxidase C)
    Publication number: 20070275083
    Abstract: The present invention provides for the identification, isolation and uses of mammalian Monoamine Oxidase C (MAO-C), also known as renalase.
    Type: Application
    Filed: March 21, 2005
    Publication date: November 29, 2007
    Inventors: Jianchao Xu, Gary Desir
  • Methods of regulating renalase (Monoamime Oxidase C)
    Publication number: 20070248585
    Abstract: The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action.
    Type: Application
    Filed: November 21, 2006
    Publication date: October 25, 2007
    Inventors: Gary Desir, Jianchao Xu
  • Compositions and methods relating to glucose metabolism, weight control, and food intake
    Patent number: 6861405
    Abstract: The present invention relates to weight control, control of body fat and food intake, and provides useful methods for treating, inter alia, obesity, diabetes and insulin insensitivity, and conditions, diseases, and disorders relating thereto. The invention also relates to methods of identifying useful compounds relating to weight loss, food intake, diabetes, and obesity, among other things, based on the discovery that inhibiting Kv1.3 activity mediates decreased food intake, weight loss, decreased body fat, increase glucose uptake, and increased insulin sensitivity, among other things.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: March 1, 2005
    Assignee: Yale University
    Inventors: Gary Desir, Jianchao Xu, Pandelakis A. Koni, Leonard Kaczmarek, Richard A. Flavell
  • Compositions and methods relating to glucose metabolism, weight control, and food intake
    Publication number: 20030032595
    Abstract: The present invention relates to weight control, control of body fat and food intake, and provides useful methods for treating, inter alia, obesity, diabetes and insulin insensitivity, and conditions, diseases, and disorders relating thereto. The invention also relates to methods of identifying useful compounds relating to weight loss, food intake, diabetes, and obesity, among other things, based on the discovery that inhibiting Kv1.3 activity mediates decreased food intake, weight loss, decreased body fat, increase glucose uptake, and increased insulin sensitivity, among other things.
    Type: Application
    Filed: June 11, 2002
    Publication date: February 13, 2003
    Inventors: Gary Desir, Jianchao Xu