Patents by Inventor Gary Jennings
Gary Jennings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20160016981Abstract: The present invention relates to amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder.Type: ApplicationFiled: May 25, 2012Publication date: January 21, 2016Applicant: GLYCOREGIMMUNE, INC.Inventors: Georg Schlechtingen, Hans-Joachim Knölker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
-
Publication number: 20150284320Abstract: The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.Type: ApplicationFiled: May 25, 2012Publication date: October 8, 2015Applicant: GLYCOREGIMMUNE, INC.Inventors: Georg Schlechtingen, Hans-Joachim Knölker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
-
Publication number: 20150232418Abstract: The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.Type: ApplicationFiled: May 25, 2012Publication date: August 20, 2015Applicant: GLYCOREGIMMUNE, INC.Inventors: Georg Schlechtingen, Hans-Joachim Knolker, Tim Friedrichson, Gary Jennings, Tobias Braxmeier
-
Patent number: 8394785Abstract: The present invention relates to a method for the treatment and/or amelioration of urticaria, the method comprising the administration of a pharmaceutically active dose of a compound of formula I to a subject in need of such a treatment and/or amelioration.Type: GrantFiled: July 6, 2011Date of Patent: March 12, 2013Assignee: Jado Technologies GmbHInventors: Tobias Braxmeier, Tim Friedrichson, Gary Jennings
-
Publication number: 20110263531Abstract: The present invention relates of the use of certain inner ionic (zwitter ionic) phospholipids, phosphonolipids and phosphate derivatives for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of an immunological disorder related to mast cell sensitization and/or activation. Preferred in this context are Edelfosine, Miltefosine and Perifosine. In a particularly preferred embodiment, the present invention relates to the use of Miltefosine for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of allergic diseases, in particular acute hyperallergic diseases, like asthma, atopic dermatitis and mastocytosis.Type: ApplicationFiled: July 6, 2011Publication date: October 27, 2011Inventors: Tobias BRAXMEIER, Tim FRIEDRICHSON, Gary JENNINGS
-
Publication number: 20110212122Abstract: The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen, wherein said antigen is NGF antigen. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of pain. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.Type: ApplicationFiled: December 22, 2008Publication date: September 1, 2011Inventors: Martin Bachmann, Gary Jennings, Till Röhn
-
Patent number: 7998945Abstract: The present invention relates to a method for the treatment and/or amelioration of atopic dermatitis, the method including the administration of a pharmaceutically active dose of a compound selected from miltefosine, edelfosine, perifosine and ilmofosine to a subject in need of such a treatment and/or amelioration.Type: GrantFiled: December 20, 2006Date of Patent: August 16, 2011Assignee: Jado Technologies GmbHInventors: Tobias Braxmeier, Tim Friedrichson, Gary Jennings
-
Publication number: 20100063126Abstract: The present invention relates to the use of specific carbazole derivatives in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.Type: ApplicationFiled: June 29, 2005Publication date: March 11, 2010Applicants: JadoLabs GmbH, Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V., Technische Universitat DresdenInventors: Tobias Braxmeier, Tim Friedrichson, Wolfgang Fröhner, Gary Jennings, Georg Schlechtingen, Cornella Schroeder, Hans-Joachim Knölker, Kai Simons, Marino Zerial, Teymuras Kurzchalia
-
Patent number: 7629385Abstract: The present invention relates to specific sphingolipids/sphingolipid derivatives as pharmaceutical compositions as well as their use in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.Type: GrantFiled: June 29, 2005Date of Patent: December 8, 2009Assignees: Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V., Technische Universität Dresden, Jado Technologies GmbHInventors: Tobias Braxmeier, Tim Friedrichson, Wolfgang Fröhner, Gary Jennings, Georg Schlechtingen, Cornelia Schroeder, Hans-Joachim Knölker, Kai Simons, Marino Zerial, Teymuras Kurzchalia
-
Publication number: 20090155302Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an array comprising a protein or peptide of IL-5, IL-13 or eotaxin. More specifically, the invention provides a composition comprising a virus-like particle and at least one protein, or peptide of IL-5, IL-13 and/or eotaxin bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of allergic diseases with an eosinophilic component and as a pharmaccine to prevent or cure allergic diseases with an eosinophilic component and to efficiently induce immune responses, in particular antibody responses.Type: ApplicationFiled: August 29, 2008Publication date: June 18, 2009Applicant: Cytos Biotechnology AGInventors: Martin F. BACHMANN, Gary Jennings, Ivo Sonderegger
-
Publication number: 20090028886Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising a virus like particle (VLP) and at least one GnRH peptide or fragment or variant thereof linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of GnRH-related diseases and conditions and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.Type: ApplicationFiled: August 4, 2005Publication date: January 29, 2009Applicant: CYTOS BIOTECHNOLOGY AGInventors: Martin F Bachmann, Alma Fulurija, Gary Jennings, Edwin Meijerink
-
Publication number: 20090018105Abstract: The present invention relates of the use of certain inner ionic (zwitter ionic) phospholipids, phosphonolipids and phosphate derivatives for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of an immunological disorder related to mast cell sensitization. Preferred in this context are edelfosine and miltefosine. In a particularly preferred embodiment, the present invention relates to the use of miltefosine for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of allergic diseases, in particular acute hyperallergic diseases, like asthma.Type: ApplicationFiled: December 20, 2006Publication date: January 15, 2009Inventors: Tobias Braxmeier, Tim Friedrichson, Gary Jennings
-
Publication number: 20080317767Abstract: The present invention relates to a compound comprising a tripartite structure in the format C-B-A or C?-B?-A? wherein moiety A and moiety A? is a raftophile, moiety B and moiety B? is a linker, moiety C and moiety C? is a pharmacophore; and wherein moiety B and B? is a linker which has a backbone of at least 8 carbon atoms and wherein one or more of said carbon atoms may be replaced by nitrogen, oxygen or sulfur. Furthermore, specific medical and pharmaceutical uses of the compounds of the invention are disclosed.Type: ApplicationFiled: April 8, 2005Publication date: December 25, 2008Inventors: Tobias Braxmeier, Tim Friedrichson, Wolfgang Frohner, Gary Jennings, Michael Munick, Georg Schlechtingen, Cornelia Schroeder, Hans-Joachim Knolker, Kai Simons, Marino Zerial, Teymuras Kurzchalia
-
Publication number: 20080292652Abstract: The present invention is in the fields of medicine, immunology, virology and molecular biology. The present invention provides a composition comprising a modified virus-like (VLP) particle derived from RNA bacteriophage AP205. The invention also provides a process for producing the aforementioned VLP. The modified VLP disclosed in the present invention is useful in the production of compositions for inducing immune responses for the prevention or treatment of diseases, disorders including infectious diseases, allergies, cancers and drug addiction. Moreover, the modified VLP disclosed in the present invention is, in particular, useful to efficiently induce self-specific immune responses, in particular antibody responses.Type: ApplicationFiled: September 21, 2005Publication date: November 27, 2008Applicant: CYTOS BIOTECHNOLOGY AGInventors: Martin F Bachmann, Alain Tissot, Gary Jennings, Regina Renhofa, Paul Pumpens, Indulis Cielens
-
Publication number: 20080255076Abstract: The present invention relates to the use of specific steroid derivatives in the preparation of medicaments for the treatment or prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.Type: ApplicationFiled: June 29, 2005Publication date: October 16, 2008Applicants: JadoLabs GmbH, Max-Planck-Gesellschaft zur Forderung der Wissenschaftenhaften e.V., Technische Universitat DresdenInventors: Tobias Braxmeier, Kai Simons, Marino Zerial, Teymuras Kurzchalia, Tim Friedrichson, Wolfgang Frohner, Gary Jennings, Georg Schlechtingen, Cornelia Schroeder, Hans-Joachim Knolker
-
Patent number: 7396287Abstract: A blind rivet formed with a tubular shell, and a mandrel extending through the shell. The shell has an outwardly extending flange at one end forming a rivet head, and having a first set of radial indentations arranged around the periphery of the shell at a first distance from the rivet head, and a second set of radial indentations arranged around the periphery of the shell at a second distance from the rivet head. Each of the radial indentations are formed by crimping them in the rivet shell after the shell has been positioned around the mandrel with the end of the shell remote from the rivet head defining the blind end of the rivet shell. Lastly, the mandrel having a head formed at one end to abut against the blind end of the shell, and the stem extending from the head having a point of weakness part way along the length thereof disposed within the shell.Type: GrantFiled: October 2, 2006Date of Patent: July 8, 2008Assignee: Newfrey LLCInventors: Gary Jennings, Peter C Probert
-
Publication number: 20080090913Abstract: The present invention relates to specific sphingolipids/sphingolipid derivatives as pharmaceutical compositions as well as their use in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.Type: ApplicationFiled: June 29, 2005Publication date: April 17, 2008Inventors: Tobias Braxmeier, Tim Friedrichson, Wolfgang Frohner, Gary Jennings, Georg Schlechtingen, Cornelia Schroeder, Hans-Joachim Knolker, Kai Simons, Marino Zerial, Teymuras Kurzchalia
-
Publication number: 20070147971Abstract: A blind rivet formed with a tubular shell, and a mandrel extending through the shell. The shell has an outwardly extending flange at one end forming a rivet head, and having a first set of radial indentations arranged around the periphery of the shell at a first distance from the rivet head, and a second set of radial indentations arranged around the periphery of the shell at a second distance from the rivet head. Each of the radial indentations are formed by crimping them in the rivet shell after the shell has been positioned around the mandrel with the end of the shell remote from the rivet head defining the blind end of the rivet shell. Lastly, the mandrel having a head formed at one end to abut against the blind end of the shell, and the stem extending from the head having a point of weakness part way along the length thereof disposed within the shell.Type: ApplicationFiled: October 2, 2006Publication date: June 28, 2007Inventors: Gary Jennings, Peter Probert
-
Publication number: 20070093441Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an array comprising a protein or peptide of IL-5, IL-13 or eotaxin. More specifically, the invention provides a composition comprising a virus-like particle and at least one protein, or peptide of IL-5, IL-13 and/or eotaxin bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of allergic diseases with an eosinophilic component and as a pharmaccine to prevent or cure allergic diseases with an eosinophilic component and to efficiently induce immune responses, in particular antibody responses.Type: ApplicationFiled: August 7, 2006Publication date: April 26, 2007Applicant: Cytos Biotechnology AGInventors: Martin Bachmann, Gary Jennings, Ivo Sonderegger
-
Patent number: 7198283Abstract: A cart assembly comprises an undercarriage supporting a cart frame, the undercarriage having one end and a connecting portion extending from cart frame and/or the undercarriage for connecting the cart assembly with an adjacent article, the cart frame including a handle portion disposed at an elevation for manipulation by a human operator in an upright standing position to steer or otherwise control the cart assembly, and an actuating member mounted on the handle portion for actuating the connecting portion between a first connecting position and a second disconnecting position.Type: GrantFiled: March 5, 2004Date of Patent: April 3, 2007Assignee: Honda Motor Co., Ltd.Inventors: Bryan Van Den Bosch, Roy Potts, John Mariciak, Bryan Jennings, Gary Jennings