Abstract: A system and method for measuring and analyzing motility within a body lumen such as the gastrointestinal (GI) tract, where an in vivo imaging device such as a capsule captures images and transmits the images to a processor, which calculates the motility of the device based on comparison of the images. Preferably, the processor compares the intensity of pairs of images or of elements of pairs of images, generates a variance for the compared images, and calculates the motility of the imaging device from the variances. The motility data may be presented to a user in various manners; for example, a plot of motility over time may be generated, or indications of low motility may be presented to the user of the system.

Abstract: Embodiments of the present invention provide a system and method for searching for a specific image or another feature in a database, for example, a database of pathologies, the image being produced by for example an in vivo imaging device such as an ingestible capsule.

Abstract: An in-vivo sensing system and a method for creating a summarized graphical presentation of a data stream captured in-vivo. The graphical presentation may be in the form of a series of summarized data points, for example a color bar. The color bar may be a fixed display along side a streaming display of the data stream. A cursor, icon or other indicator may move along the fixed color bar as the data stream is displayed and/or streamed so as to indicate to a health professional what part of the data stream may be currently displayed. The color content in the color bat may map out the data stream and give indication of the location of anatomical sites as well as possible locations of pathology.

Abstract: A device, method and system for sensing the temperature or temperature change of an environment. A typically in-vivo device includes an image sensor. The device may sense the dark current noise of the image sensor, and calculate the temperature or a temperature change of the image sensor.

Abstract: A device, system and method may enable the obtaining of in vivo images from within body lumens or cavities, such as images the gastrointestinal (GI) tract, where the data such as image data is typically transmitted or otherwise sent to a receiving system in compressed or diluted form. The image may be reconstructed and for example displayed to a user.

Abstract: A system and method allows for the annotation of an image stream, which may be produced by, for example, an ingestible capsule. A workstation accepts images acquired by the capsule and displays the images on a monitor as a moving image. A user inputs an annotation which corresponds to a portion of the moving image, and the annotation is recorded in a database associated with the selected portion. The annotation may include, for example, textual notes regarding the image portion. The annotations may be displayed at a later time.

Abstract: An energy saving method for acquiring in vivo images of the gastro-intestinal tract is provided. A device, such as an autonomous capsule, includes at least one imaging unit; a control unit connected to the imaging unit and a power supply connected to the control unit. The control unit includes a switching unit and an axial motion detector connected to the switching unit. The axial motion detector detects the axial movement of the device and if the axial acceleration is below a pre-determined threshold, disconnects the power supply thereby preventing the acquisition of redundant images. A method for operation and use of the device is provided.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.

Abstract: An in vivo examining device and method are described. The in vivo examining device has two operational phases; an initial phase in which the device is of initial dimensions and a final phase in which the device is of final dimensions. In the initial phase the device can pass freely through a normally configured body lumen whereas it may not be able to pass freely through an abnormally configured lumen. In the final phase the device can pass freely through a body lumen even if it is abnormally configured.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.

Abstract: A device, system and method for selectively activating or altering the operational mode of an autonomous in vivo device in response to in vivo conditions. The system includes an in vivo sensing device with a condition tester, and a controller. The in vivo sensing device may be in communication with an external receiver.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.

Abstract: The present invention provides an optical system for illuminating and viewing a target in which an illumination element and a receiving means are disposed behind a single optical window, and which obtains data essentially free of backscatter and stray light. The optical window of the optical system is configured such that it defines a shape having at least one focal curve, i.e., an ellipsoid shaped dome.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.

Abstract: Systems and methods which vary the frame capture rate of the camera and/or frame display rate of the display unit of in vivo camera systems are discussed. The capture rate is varied based on physical measurements related to the motion of the camera. Alternatively, the frame capture rate is varied based on comparative image processing of a plurality of frames. The frame display rate of the system is varied based on comparative image processing of a multiplicity of frames. Both the frame capture and the frame display rates of such systems can be varied concurrently.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and an ultra low power radio frequency transmitter for transmitting signals from the CMOS imaging camera to a receiving system located outside a patient. The imaging system includes at least one CMOS imaging camera, at least one illumination source for illuminating an in vivo site and an optical system for imaging the in vivo site onto the CMOS imaging camera.

Abstract: A system and method for maneuvering a device in vivo, wherein a tube has a longitudinal axis, a distal end and a proximal end, and an in vivo sensing device is changeably connected to the distal end of the tube. Typically, the sensing device may be moved from one position where it is, for example, within the axial profile of the tube or along the longitudinal axis of the tube, to a second position, where it is not.

Abstract: An autonomous device that may include for example a camera, a transmitter for transmitting a signal from the camera and a storage compartment for retaining a substance in the device. A method of delivering a medicament to a patient including imaging a gastrointestinal tract with an autonomous device, identifying a target location in such tract, and releasing a medicament from the device at the target location.

Abstract: A system and method for in vivo diagnosis are provided. A composition consisting of at least a marking agent and a pharmaceutically acceptable carrier is administered to a patient and an autonomous in vivo device, which includes an illumination source and an image sensor, is used to obtain endo luminal images of the patient.

Abstract: A system and method for measuring and analyzing motility within a body lumen such as the gastrointestinal (GI) tract, where an in vivo imaging device such as a capsule captures images and transmits the images to a processor, which calculates the motility of the device based on comparison of the images. Preferably, the processor compares the intensity of pairs of images or of elements of pairs of images, generates a variance for the compared images, and calculates the motility of the imaging device from the variances. The motility data may be presented to a user in various manners; for example, a plot of motility over time may be generated, or indications of low motility may be presented to the user of the system.