Abstract: An image sensor (e.g., a CMOS sensor) includes a pixel array portion and a circuitry portion, where the circuitry portion may be segregated, for example longitudinally, from the pixel array portion.

Abstract: An in vivo examining device and method are described. The in vivo examining device has two operational phases; an initial phase in which the device is of initial dimensions and a final phase in which the device is of final dimensions. In the initial phase the device can pass freely through a normally configured body lumen whereas it may not be able to pass freely through an abnormally configured lumen. In the final phase the device can pass freely through a body lumen even if it is abnormally configured.

Abstract: An in vivo imaging device including at least one image sensor and an energy receiving unit that is configured to receive electromagnetic energy and to convert the received electromagnetic energy to energy for powering at least one electrical component of the image sensor.

Abstract: Capsule (60) moves through the gastrointestinal tract (62) in a first pass to generate a map of the gastrointestinal tract, and to identify a location of interest. In its second pass, capsule (60) moves through the gastrointestinal tract, and is controlled to perform a job at the identified location. Repeated localizations generate generate a map of the route taken by the capsule in the gastrointestinal tract (62). images displayed on the image monitor (61) are compared with the generated map displayed on the position monitor (63) to identify the location of a pathology (72).

Abstract: A system and method for measuring and analyzing motility within a body lumen such as the gastrointestinal (GI) tract, where an in vivo imaging device such as a capsule captures images and transmits the images to a processor, which calculates the motility of the device based on comparison of the images. Preferably, the processor compares the intensity of pairs of images or of elements of pairs of images, generates a variance for the compared images, and calculates the motility of the imaging device from the variances. The motility data may be presented to a user in various manners; for example, a plot of motility over time may be generated, or indications of low motility may be presented to the user of the system.

Abstract: The present invention provides an optical system for illuminating and viewing a target in which an illumination element and a receiving means are disposed behind a single optical window, and which obtains data essentially free of backscatter and stray light. The optical window of the optical system is configured such that it defines a shape having at least one focal curve, i.e., an ellipsoid shaped dome. The illumination element and the receiving means are geometrically positioned on the focal curve plane or in proximity of the focal curve plane, such that, when illuminating, rays from the illumination elements, that are internally reflected from the optical window, will not be incident on the receiving means.

Abstract: The present invention provides an optical system for illuminating and viewing a target in which an illumination element and a receiving means are disposed behind a single optical window, and which obtains data essentially free of backscatter and stray light. The optical window of the optical system is configured such that it defines a shape having at least one focal curve, i.e., an ellipsoid shaped dome. The illumination element and the receiving means are geometrically positioned on the focal curve plane or in proximity of the focal curve plane, such that, when illuminating, rays from the illumination elements, that are internally reflected from the optical window, will not be incident on the receiving means.

Abstract: An in-vivo imaging device including a camera may include a frame storage device. Systems and methods which vary the frame capture rate of the camera and/or frame display rate of the display unit of in-vivo camera systems are discussed. The capture rate is varied based on physical measurements related to the motion of the camera. Alternatively, the frame capture rate is varied based on comparative image processing of a plurality of frames. The frame display rate of the system is varied based on comparative image processing of a multiplicity of frames. Both the frame capture and the frame display rates of such systems can be varied concurrently.

Abstract: A system and method may determine the orientation of an in-vivo imaging device relative to the earth's gravitation field. Some embodiments may enable indication of specific locations where other methods provide non-satisfactory imaging coverage. The system may include an in-vivo imaging system with a container or shell containing an orientation object. The container may be placed in at least one optical dome or optical field of an in-vivo imaging device, such as an autonomous capsule. The location of the orientation object's image on the in-vivo imaging device imager, as well as size of the image, may be determined as functions of the location of the orientation object inside the container, for each image acquired.

Abstract: It is an object of the present invention to provide a device and method for controlled positioning and/or releasing an object in a body lumen. The device of the invention comprises a liquid filled tube detachably connected to an injecting apparatus at its proximal end and to a holding and releasing unit having a bore configured to hold and release the object, at its distal end. The holding and releasing unit is connected to the tube such that liquid can pass from the tube into the holding and releasing unit bore. The distal end of the tube is capable of being inserted and maneuvered through a body lumen. The object is retained in the device during its manipulation through the body lumen due to frictional force exerted by the holding and releasing unit on the object. The object is released by activating the injecting apparatus to achieve an hydraulic pressure in the holding and releasing unit bore which is higher than the frictional force.

Abstract: A system for performing in vivo procedures is provided. The system may include a tool for performing an in vivo procedure. The tool may have an in vivo sensor for obtaining in vivo information; a functional element for performing an interventional or diagnostic in-vivo procedure; a processor in communication with the tool for receiving and optionally processing the in vivo information obtained by the tool and a monitor in communication with the processor for displaying the optionally processed in vivo information. The communication between the elements of the system may be wireless, or, optionally, wired.

Abstract: An in-vivo device may include an optical system, and a method for viewing in-vivo sites. A dome or cover may cover an end of the device, protecting optical elements such as illumination devices or imagers, which may be behind the dome. The dome may be forward projecting. The field of view of the imager may be for example forward looking. Illumination element(s) and a receiving unit or imager may be disposed behind a single optical window, which for example may enable obtaining of images free of backscatter and stray light.

Abstract: An optical system for illuminating and viewing a target (15) in which an illumination element (16) and a receiving element (13) are disposed behind a single optical window (14), and which obtains data essentially free of backscatter and stray light. The optical window (14) is configure such that is defines a shape having at least one focal curve, i.e., an ellipsoid shape dome. The illumination element (16) and the receiving element (13) are geometrically positioned on the focal curve plane or in proximity of the focal curve plane, such that, when illuminating, rays from the illumination element internally reflected from the optical window (14) will not incident on the receiving element (13).

Abstract: The present invention provides an optical system for illuminating and viewing a target in which an illumination element and a receiving means are disposed behind a single optical window, and which obtains data essentially free of backscatter and stray light. The optical window of the optical system is configured such that it defines a shape having at least one focal curve, i.e., an ellipsoid shaped dome. The illumination element and the receiving means are geometrically positioned on the focal curve plane or in proximity of the focal curve plane, such that, when illuminating, rays from the illumination elements, that are internally reflected from the optical window, will not be incident on the receiving means.

Abstract: An energy saving method for acquiring in vivo images of the gastro-intestinal tract is provided. A device, such as an autonomous capsule, includes at least one imaging unit; a control unit connected to the imaging unit and a power supply connected to the control unit. The control unit includes a switching unit and an axial motion detector connected to the switching unit. The axial motion detector detects the axial movement of the device and if the axial acceleration is below a pre-determined threshold, disconnects the power supply thereby preventing the acquisition of redundant images. A method for operation and use of the device is provided.

Abstract: An energy saving device for acquiring in vivo images of the gastro-intestinal tract is provided. The device, such as an autonomous capsule, includes at least one imaging unit; a control unit connected to the imaging unit and a power supply connected to the control unit. The control unit includes a switching unit and an axial motion detector connected to the switching unit. The axial motion detector detects the axial movement of the device and if the axial acceleration is below a pre-determined threshold, disconnects the power supply thereby preventing the acquisition of redundant images.

Abstract: A device, system and method for capturing in-vivo images allows for size or distance estimations for objects within the images. A scale may be overlayed on or otherwise added to the images and, based on a comparison between the scale and an image of an object, the size of the object and/or the distance of the object from an imaging device may be estimated or calculated.

Abstract: A device, method and system for sensing the temperature or temperature change of an environment. A typically in-vivo device includes an image sensor. The device may sense the dark current noise of the image sensor, and calculate the temperature or a temperature change of the image sensor.

Abstract: Systems and methods which vary the frame capture rate of the camera and/or frame display rate of the display unit of in vivo camera systems are discussed. The capture rate is varied based on physical measurements related to the motion of the camera. Alternatively, the frame capture rate is varied based on comparative image processing of a plurality of frames. The frame display rate of the system is varied based on comparative image processing of a multiplicity of frames. Both the frame capture and the frame display rates of such systems can be varied concurrently.

Abstract: Systems and methods which vary the frame capture rate of the camera and/or frame display rate of the display unit of in vivo camera systems are discussed. The capture rate is varied based on physical measurements related to the motion of the camera. Alternatively, the frame capture rate is varied based on comparative image processing of a plurality of frames. The frame display rate of the system is varied based on comparative image processing of a multiplicity of frames. Both the frame capture and the frame display rates of such systems can be varied concurrently.