Patents by Inventor Geena Malhotra

Geena Malhotra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12090163
    Abstract: The invention relates to pharmaceutical compositions comprising ((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)oxy)methyl pivalate or a pharmaceutically acceptable derivative thereof, optionally with an additional agent, methods of making them, and their use in medicine.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 17, 2024
    Assignee: CIPLA LIMITED
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar, Atul Daroi, Siddharth Agrawal
  • Publication number: 20240285629
    Abstract: A pharmaceutical composition is provided comprising combination of antiretroviral drugs optionally in combination of pharmacokinetic boosters. The formulation is used for the treatment of diseases caused by retroviruses. The process of preparation of the formulation is also provided.
    Type: Application
    Filed: April 26, 2024
    Publication date: August 29, 2024
    Inventors: Geena MALHOTRA, Kalpana JOSHI, Preeti RAUT
  • Patent number: 12036358
    Abstract: The present subject matter refers a blister-strip based dispenser (100) comprising a lever arm rotatable on receiving a user-actuation. A chassis (106, 108) is provided for supporting placement of at least one blister-strip (104) in the form of the coil. The blister-strip (104) comprises medicament-pockets at at-least one side of the blister-strip (104). A plurality of interconnected-rollers (110, 114, 116) comprises at-least one roller linked to the lever-arm and rotatable by the lever arm. The plurality of interconnected rollers (110, 114, 116) are configured for anchoring the blister-strip (104) from one end for enabling the placement in a coil-form and unwinding of the blister strip (104) from the coil-form, guiding at least two split-portions of the blister-strip (104), anchoring an end of each of said at-least two portions of the blister-strip (104) for winding the at-least two portions separately, and anchoring an end of a lid-foil peeled off the at least two portions for winding the lid-foil.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: July 16, 2024
    Assignee: CIPLA LIMITED
    Inventors: Nandan Kulkarni, Pavan Shewale, Geena Malhotra
  • Publication number: 20240016814
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of desipramine or a salt thereof. The compositions include an effective amount of desipramine or a salt thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Application
    Filed: April 17, 2023
    Publication date: January 18, 2024
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20230390293
    Abstract: This invention relates to novel pharmaceutical formulations of Bruton's tyrosine kinase (BTK) inhibitor Ibrutinib. This invention also relates to methods of using the Ibrutinib pharmaceutical formulations, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, cancers, including lymphoma, and inflammatory diseases or conditions.
    Type: Application
    Filed: May 3, 2023
    Publication date: December 7, 2023
    Inventors: Geena Malhotra, Jinesh Chauhan, Kishore Kothule, Ravichandra Bhadravathi Vedamurthy, Anirban Mallik Thakur
  • Publication number: 20230119206
    Abstract: A pharmaceutical compositions provided for the treatment of proliferative disorders. The composition comprises a therapeutically effective amount of ibrutinib and a therapeutically effective amount of at least one alkaloid or derivative thereof. Methods and kits are also provided.
    Type: Application
    Filed: October 27, 2022
    Publication date: April 20, 2023
    Inventor: Geena Malhotra
  • Patent number: 11612612
    Abstract: An oral or injectable pharmaceutical composition is provided for treating diseases caused by retroviruses or hepatitis B viruses. The composition comprises a therapeutically effective amount of at least one anti-retroviral drug and a therapeutically effective amount of at least one pharmacokinetic booster or enhancer or derivative thereof. Methods and kits are also provided.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: March 28, 2023
    Assignee: CIPLA LIMITED
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar, Preeti Raut
  • Patent number: 11596597
    Abstract: A pharmaceutical long acting depot composition is provided as an aid to smoking cessation treatment. The formulation comprises a therapeutically effective amount of varenicline or its pharmaceutically acceptable derivative and pharmaceutically acceptable excipients. The process of preparation of the formulation is also provided.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: March 7, 2023
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Sarabjit Singh
  • Publication number: 20230030113
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of Quetiapine or derivative thereof. The compositions include an effective amount of Quetiapine or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Application
    Filed: September 22, 2022
    Publication date: February 2, 2023
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Patent number: 11478483
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of Quetiapine or derivative thereof. The compositions include an effective amount of Quetiapine or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: October 25, 2022
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20220331289
    Abstract: The present invention relates to pharmaceutical composition for intranasal or pulmonary delivery, wherein the composition comprises an artemisinin derivative and optionally one or more pharmaceutically acceptable excipients. The pharmaceutical composition may be for intranasal delivery, may be in the form of a nasal spray, a solution, a suspension, nasal drops, an insufflation powder or a nasal powder, and may be suitable for delivery using a nebulizer, insufflator, powder sprayer or powder inhaler. Alternatively, the pharmaceutical composition may be for pulmonary delivery, may be in the form of an aerosol composition or a powder, and may be suitable for delivery using a metered dose inhaler (MDI) or a dry powder inhaler (DPI). The present invention also relates to processes for preparing such compositions and to the use of such compositions for the treatment of malaria.
    Type: Application
    Filed: April 20, 2022
    Publication date: October 20, 2022
    Inventors: Preeti RAUT, Geena MALHOTRA
  • Patent number: 11464425
    Abstract: A flow-sensing arrangement within a spirometer. The arrangement includes a tubular-member for allowing an air-passage along a longitudinal-axis thereof. At-least two disc-shaped air-resistive elements are removably-arranged within the tubular member to resist the air-flow. Each of the resistive-elements include perforations for allowing the air-passage through the resistive-element. At-least two ports extend radially outward through a wall of the tubular member, such that each of the two ports are located within the tubular-member near the resistive-elements to cause determination of at least a pressure-difference there-between.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: October 11, 2022
    Assignee: CIPLA LIMITED
    Inventors: Nandan Kulkarni, Vidur Malhotra, Geena Malhotra, Brinder Ahluwalia
  • Patent number: 11390637
    Abstract: The present invention relates to certain acid salts of (((1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methyl)(phenoxy) phosphoryloxy)methyl pivalate of Formula (I), to processes for their preparation; to pharmaceutical compositions comprising such compounds, and methods of treating a disease which responds to inhibition of nucleotide reverse transcriptase activity.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: July 19, 2022
    Assignee: Cipla Limited
    Inventors: Manjinder Singh Phull, Ashwini Amol Sawant, Dharmaraj Ramachandra Rao, Geena Malhotra, Manish Gopaldas Gangrade
  • Publication number: 20220110938
    Abstract: A pharmaceutical composition is provided comprising combination of antiretroviral drugs optionally in combination of pharmacokinetic boosters. The formulation is used for the treatment of diseases caused by retroviruses. The process of preparation of the formulation is also provided.
    Type: Application
    Filed: December 20, 2021
    Publication date: April 14, 2022
    Inventors: Geena MALHOTRA, Kalpana JOSHI, Preeti RAUT
  • Publication number: 20220036766
    Abstract: An apparatus (100), a system (200), and a method (500) for simulating deposition of an inhaled drug on lungs of an individual are disclosed. The apparatus (100) includes a mouth-throat model (102), an inhalation device (104), and a breath simulator (106) connected to the mouth-throat model (102) for dispersing drug and respiration flow respectively in the mouth-throat model (102). The apparatus (100) also includes a controlling unit (108) in communication with the breath simulator (106) and the inhalation device (104) to detect the dispersion of the respiration flow and actuate the inhalation device (104) to disperse the drug. The respiration flow and the drug are uniformly mixed while passing through a mixing unit (110) formed downstream to the mouth-throat model (102) and the breath simulator (106). The mixture is then received by a lung cast model (112) formed downstream to the mixing unit (110) to accommodate deposition of the drug.
    Type: Application
    Filed: April 24, 2020
    Publication date: February 3, 2022
    Inventors: Nandan KULKARNI, Geena MALHOTRA
  • Patent number: 11234981
    Abstract: A pharmaceutical composition is provided comprising combination of antiretroviral drugs optionally in combination of pharmacokinetic boosters. The formulation is used for the treatment of diseases caused by retroviruses. The process of preparation of the formulation is also provided.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: February 1, 2022
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Preeti Raut
  • Publication number: 20220016059
    Abstract: Methods of treating bladder cancer using adapalene are disclosed herein. Adapalene can be administered as part of a comprehensive treatment program, which can also include chemotherapy, immunotherapy, radiation therapy and/or surgical treatment.
    Type: Application
    Filed: April 2, 2021
    Publication date: January 20, 2022
    Inventors: Geena Malhotra, Kalpana Joshi
  • Patent number: 11224591
    Abstract: A pharmaceutical composition is provided for the treatment of systemic infections as well as colonic diseases. The composition comprises a therapeutically effective amount of rifaximin and a therapeutically effective amount of at least one alkaloid or derivative thereof. Methods and kits are also provided.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: January 18, 2022
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20220009929
    Abstract: Disclosed herein are crystalline polymorphic forms of Ibrutinib, methods for their preparation, pharmaceutical compositions comprising the polymorphic Forms, and their use thereof.
    Type: Application
    Filed: May 2, 2019
    Publication date: January 13, 2022
    Inventors: Ramanaiah CHENNURU, Srinivas Laxminarayan PATHI, Geena MALHOTRA, Ramesh DEVARAPALLI
  • Publication number: 20220002302
    Abstract: The present invention discloses novel crystalline polymorphic forms of Acalabrutinib, methods of preparation, pharmaceutical compositions and methods of therapeutic treatment involving polymorphic forms thereof.
    Type: Application
    Filed: September 24, 2019
    Publication date: January 6, 2022
    Inventors: Geena MALHOTRA, Venkata Srinivas PULLELA, Srinivas Laxminarayan PATHI, Ramanaiah CHENNURU, Ramesh DEVARAPALLI, Ashok MITHUN