Patents by Inventor Geena Malhotra

Geena Malhotra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Composition Comprising Deferasirox
    Publication number: 20180311216
    Abstract: The present invention relates to a pharmaceutical composition comprising deferasirox, a process for preparing such pharmaceutical composition, and its use in the treatment of chronic iron overload. The pharmaceutical composition comprises nanosized deferasirox having improved surface area and solubility. It also relates to a method for treatment of chronic iron overload which comprises administering a pharmaceutical composition comprising nanosized deferasirox.
    Type: Application
    Filed: July 3, 2018
    Publication date: November 1, 2018
    Inventors: Geena MALHOTRA, Shrinivas Madhukar PURANDARE
  • METHOD OF TREATING HYPERTENSION
    Publication number: 20180303835
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of anagrelide or derivative thereof. The compositions include an effective amount of anagrelide or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Application
    Filed: June 19, 2018
    Publication date: October 25, 2018
    Inventors: Geena Malhotra, Kalpana Joshi
  • Stable carfilzomib formulations
    Patent number: 10098890
    Abstract: Disclosed herein are stabilized formulations of carfilzomib. The formulations exhibit increased storage stability relative to other formulations, and are simpler for health care providers to prepare and administer to patients.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: October 16, 2018
    Assignee: Cipla Limited
    Inventors: Harshad Kishore Shete, Pankaj Omprakash Pathak, Sarabjit Singh, Geena Malhotra
  • Bezafibrate for the treatment of cancer
    Patent number: 10098860
    Abstract: Methods of treating renal cancer, including renal cell carcinoma, using bezafibrate are disclosed herein. Bezafibrate can be administered as a monotherapy or as part of a comprehensive treatment program, which can also include administration with other anti-cancer drugs, surgical treatments or exposure to ionizing radiation.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: October 16, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Methods for the treatment of hepatitis C
    Patent number: 10071062
    Abstract: The present invention relates to method of treatment of hepatitis C using hexestrol or a derivative thereof. The methods of the present invention can be used in patients with hepatitis C administering hexestrol or a derivative thereof in combination with one or more anti-hepatitis C drugs.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: September 11, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi
  • Pharmaceutical Antiretroviral Composition
    Publication number: 20180250271
    Abstract: A pharmaceutical composition comprises at least one integrase inhibitor or its salt, solvate, complex, hydrate, isomer, ester, tautomer, anhydrate, enantiomer, polymorph or prodrug and at least one antiretroviral or anti-HIV agent or its salt, solvate, complex, hydrate, isomer, ester, tautomer, anhydrate, enantiomer, polymorph or prodrug.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 6, 2018
    Inventors: Geena MALHOTRA, Shrinivas PURANDARE
  • Method of treating pulmonary arterial hypertension
    Patent number: 10058545
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of cinitapride or derivative thereof. The compositions include an effective amount of cinitapride or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: August 28, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • IMPROVED PROCESS FOR THE PREPARATION OF APREMILAST
    Publication number: 20180237390
    Abstract: The present invention relates to novel processes for the preparation of apremilast of formula I, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 15, 2016
    Publication date: August 23, 2018
    Inventors: Dharmaraj Ramachandra RAO, Geena MALHOTRA, Srinivas Laxminarayan PATHI, Ravikumar PUPPALA, Suryanarayana Durga YARRA
  • Methazolamide for the treatment of cancer
    Patent number: 10039752
    Abstract: The present invention relates to methods of using methazolamide to treat pancreatic cancer. Pancreatic cancer can be treated by administering to a patient in need thereof an effective amount of methazolamide, optionally in combination with one or more additional cancer therapies.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: August 7, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Method of treating hypertension
    Patent number: 10022377
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of anagrelide or derivative thereof. The compositions include an effective amount of anagrelide or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Grant
    Filed: November 24, 2016
    Date of Patent: July 17, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi
  • THIENOPYRIDINE DERIVATIVE FOR THE TREATMENT OF HEPATITIS C INFECTIONS
    Publication number: 20180193322
    Abstract: The present invention relates to methods of treatment of hepatitis C using prasugrel. The methods of the present invention can be used in patients with hepatitis C administering prasugrel in combination with one or more anti-hepatitis C drugs.
    Type: Application
    Filed: March 6, 2018
    Publication date: July 12, 2018
    Inventors: Karl Roberts, Geena Malhotra, Dhiraj Abhyankar, Kalpana Joshi, Jeevan Ghosalkar
  • Treatment of hepatitis C using histone deacetylase inhibitors
    Patent number: 10016377
    Abstract: The present invention relates to method of treatment of hepatitis C using bufexamac or a derivative thereof. The methods of the present invention can be used in patients with hepatitis C administering bufexamac or a derivative thereof in combination with one or more anti-hepatitis C drugs.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: July 10, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi
  • Pharmaceutical antiretroviral composition
    Patent number: 10004721
    Abstract: A pharmaceutical composition comprises at least one integrase inhibitor or its salt, solvate, complex, hydrate, isomer, ester, tautomer, anhydrate, enantiomer, polymorph or prodrug and at least one antiretroviral or anti-HIV agent or its salt, solvate, complex, hydrate, isomer, ester, tautomer, anhydrate, enantiomer, polymorph or prodrug.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: June 26, 2018
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Shrinivas Purandare
  • STABILIZED LIQUID FOSAPREPITANT FORMULATIONS
    Publication number: 20180153913
    Abstract: The present invention relates to stable pharmaceutical compositions of fosaprepitant or a salt thereof in the form of ready-to-use or ready-to-dilute compositions suitable for parenteral administration.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Inventors: Geena Malhotra, Sarabjit Singh, Abhijit Jadhav
  • INHALER DEVICE
    Publication number: 20180140789
    Abstract: An inhaler for delivering a powdered medicament from a container. The inhaler includes a flow channel, an opening means and a housing. The flow channel includes a conduit extending from an inlet to an outlet and includes a medicament introduction region within which a powdered medicament can be introduced. The housing includes a loading member which includes a holder for receiving a medicament container. The loading member can be manually moved between a loading position, in which a container can be manually loaded into, or removed from, the holder, and an inhalation position in which the powdered medicament can be introduced into the flow channel. The movement of the loading member from the loading position to the inhalation position causes the opening means to break a seal on the container, thereby exposing the powdered medicament for introduction into the flow channel.
    Type: Application
    Filed: May 11, 2016
    Publication date: May 24, 2018
    Inventors: Frank PIETERS, Geena MALHOTRA
  • STABLE CARFILZOMIB FORMULATIONS
    Publication number: 20180117054
    Abstract: Disclosed herein are stabilized formulations of carfilzomib. The formulations exhibit increased storage stability relative to other formulations, and are simpler for health care providers to prepare and administer to patients.
    Type: Application
    Filed: October 27, 2017
    Publication date: May 3, 2018
    Inventors: Harshad Kishore Shete, Pankaj Omprakash Pathak, Sarabjit Singh, Geena Malhotra
  • Novel Polymorphic Form X of Nilotinib Dihydrochloride Hydrate
    Publication number: 20180111915
    Abstract: The present invention relates to a novel polymorph of nilotinib hydrochloride (Form X), to processes for its preparation, to pharmaceutical compositions containing the same and to its use in medicine.
    Type: Application
    Filed: March 21, 2016
    Publication date: April 26, 2018
    Applicant: Cipla Limited
    Inventors: Dharmaraj Ramachandra RAO, Geena MALHOTRA, Srinivas Laxminarayan PATHI, Venugopalarao CHINIMILLI, Manish Gopaldas GANGRADE
  • Stabilized Cabazitaxel Formulations
    Publication number: 20180104212
    Abstract: Disclosed herein are improved formulations for the cabazitaxel. The formulations exhibit increased storage stability relative to other formulations, and are simpler for health care providers to prepare and administer to patients.
    Type: Application
    Filed: December 19, 2017
    Publication date: April 19, 2018
    Inventors: Geena Malhotra, Sarabjit Singh, Ravichandra Bhadravathi Vedamurthy, Anirban Mallik Thakur, Dhiraj Abhyankar
  • Thienopyridine derivative for the treatment of hepatitis C infections
    Patent number: 9937160
    Abstract: The present invention relates to methods of treatment of hepatitis C using prasugrel. The methods of the present invention can be used in patients with hepatitis C administering prasugrel in combination with one or more anti-hepatitis C drugs.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: April 10, 2018
    Assignee: Cipla (UK) Limited
    Inventors: Karl Roberts, Geena Malhotra, Dhiraj Abhyankar, Kalpana Joshi, Jeevan Ghosalkar
  • Process for the synthesis of everolimus and intermediates thereof
    Patent number: 9938297
    Abstract: The present invention relates to a novel process for the synthesis of everolimus of formula (I): and intermediates thereof.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: April 10, 2018
    Assignee: Cipia Limited
    Inventors: Dharmaraj Ramachandra Rao, Geena Malhotra, Venkata Srinivas Pullela, Vinod Parameshwaran Acharya