Patents by Inventor Geert Jannes

Geert Jannes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6858387
    Abstract: The current invention relates to the field of detection and identification of clinically important fungi. More particularely, the present invention relates to species specific probes originating from the Internal Transcribed Spacer (ITS) region of rDNA for the detection of fungal species such as Candida albicans, Candida parapsilosis, Candida tropicalis, Candida kefyr, Candida krusei, Candida glabrata, Candida dubliniensis, Aspergillus flavus, Aspergillus versicolor, Aspergillus nidulans, Aspergillus fumigatus, Cyptococcus neoformans and Pneumocystis carinii in clinical samples, and methods using said probes.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: February 22, 2005
    Assignees: Innogenetics, N.V., Enterprise Ireland
    Inventors: Terry Smith, Majella Maher, Cara Martin, Geert Jannes, Rudi Rossau, Marjo Van Der Weide
  • Patent number: 6811978
    Abstract: The present invention relates to 16S-23S rRNA spacer sequences from Pseudomonas species and their use in a method for detection and/or identification of Pseudomonas species. The invention further it relates to a method for detection and identification of at least one Pseudomonas species, or for the simultaneous detection of several Pseudomonas species in a sample, involving the steps of: (i) optionally releasing, isolating and/or concentrating the polynucleic acids present in the sample; (ii) optionally amplifying the 16S-23S rRNA spacer region, or a part thereof, with at least one primer pair; (iii) detecting the presence of a 16S-23S rRNA spacer sequence; and (iv) identifying the Pseudomonas species present in the sample from the nucleic acid(s) detected in the sample.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: November 2, 2004
    Assignee: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Publication number: 20030215802
    Abstract: The present invention relates to a method for detection and identification of at least one microorganism, or for the simultaneous detection of several microorganisms in a sample.
    Type: Application
    Filed: August 17, 2001
    Publication date: November 20, 2003
    Applicant: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6632607
    Abstract: Method for the detection of the antibiotic resistance spectrum of Mycobacterium species present in a sample, possibly caused to the identification of the Mycobacterium species involved, comprising the steps of: (i) if need be releasing, isolating or concentrating the polynucleic acids present in the sample; (ii) if need be amplifying the relevant part of the antibiotic resistance genes present in said sample with at least one suitable primer pair; (iii) hybridizing the polynucleic acids of step (i) or (ii) with at least one of the rpoB gene probes, as specified in table 2, under the appropriate hybridization and wash conditions; (iv) detecting the hybrids formed in step (iii); (v) inferring the Mycobacterium antibiotic resistance spectrum, and possibly the Mycobacterium species involved from the differential hybridization signal(s) obtained in step (iv).
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: October 14, 2003
    Assignee: Innogenetics N.V.
    Inventors: Hans De Beenhouwer, Fran├žoise Portaels, Lieve Machtelinckx, Geert Jannes, Rudi Rossau
  • Publication number: 20030152982
    Abstract: Method for the detection of the antibiotic resistance spectrum of Mycobacterium species present in a sample, possibly coupled to the identification of the Micobacterium species involved, comprising the steps of: (i) if need be releasing, isolating or concentrating the polynucleic acids present in the sample; (ii) if need be amplifying the relevant part of the antibiotic resistance genes present in said sample with at least one suitable primer pair; (iii) hybridizing the polynucleic acids of step (i) or (ii) with at least one of the rpoB gene probes, as specified in table 2, under the appropriate hybridization and wash conditions; (iv) detecting the hybrids formed in step (iii); (v) inferring the Mycobacterium antibiotic resistance spectrum, and possibly the Mycobacterium species involved from the differential hybridization signal(s) obtained in step (iv).
    Type: Application
    Filed: January 10, 2003
    Publication date: August 14, 2003
    Inventors: Hans De Beenhouwer, Francoise Portaels, Lieve Machtelinckx, Geert Jannes, Rudi Rossau
  • Patent number: 6329138
    Abstract: Method for the detection of the antibiotic resistance spectrum of Mycobacterium species present in a sample, possibly coupled to the identification of the Mycobacterium species involved, comprising the steps of: (i) if need be releasing, isolating or concentrating the polynucleic acids present in the sample; (ii) if need be amplifying the relevant part of the antibiotic resistance genes present in said sample with at least one suitable primer pair; (iii) hybridizing the polynucleic acids of step (i) or (ii) with at least one of the rpoB gene probes, as specified in table 2, under the appropriate hybridization and wash conditions, (iv) detecting the hybrids formed in step (iii); (v) inferring the Mycobacterium antibiotic resistance spectrum, and possibly the Mycobacterium species involved from the differential hybridization signal(s) obtained in step (iv).
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: December 11, 2001
    Assignee: Innogenetics, N.V.
    Inventors: Hans De Beenhouwer, Fran├žoise Portaels, Lieve Machtel nckx, Geert Jannes, Rudi Rossau
  • Patent number: 6312903
    Abstract: The present invention relates to a method for detection and identification of at least one microorganism, or for the simultaneous detection of several microorganisms in a sample, involving the steps of: (i) if need be releasing, isolating or concentrating the polynucleic acids present in the sample; (ii) if need be amplifying the 16S-235 rRNA spacer region, or a part of it, with at least one suitable primer pair; (iii) hybridizing the polynucleic acids of step (i) or (ii) with at least one and preferably more than one of the spacer probes as mentioned in table la or equivalents of thereof, under the appropriate hybridization and wash conditions, and/or with a taxon-specific probe derived from any of the spacer sequences as represented in FIGS.
    Type: Grant
    Filed: November 29, 1999
    Date of Patent: November 6, 2001
    Assignee: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn
  • Patent number: 6025132
    Abstract: The present invention relates to a method for detection and identification of at least one microorganism, or for the simultaneous detection of several microorganisms in a sample, comprising the steps of: (i) if need be releasing, isolating or concentrating the polynucleic acids present in the sample; (ii) if need be amplifying the 16S-23S rRNA spacer region, or a part of it, with at least one suitable primer pair, (iii) hybridizing the polynucleic acids of step (i) or (ii) with at least one and preferably more than one of the spacer probes as mentioned in table 1a or equivalents of thereof, under the appropriate hybridization arid wash conditions, and/or with a taxon-specific probe derived from any of the spacer sequences as represented in FIGS.
    Type: Grant
    Filed: December 23, 1996
    Date of Patent: February 15, 2000
    Assignee: Innogenetics N.V.
    Inventors: Geert Jannes, Rudi Rossau, Hugo Van Heuverswyn