Abstract: A PHSRN-RGD-containing oligopeptide and a composition for promoting bone formation, which contains such oligopeptide as an effective ingredient. The oligopeptide promotes osteoblastic cell adhesion and differentiation and enhances bone regenerative ability, so that the inventive oligopeptide can be effectively used in regenerative treatment of bone tissue and periodontal tissue.

Abstract: The present invention relates to a composition for treating alopecia or promoting hair growth, which contains the blood plasma or serum as an active ingredient. The inventive composition is effective in hair growth, hair growth promotion and hair loss prevention.

Abstract: The invention provides novel inhibitory polynucleotides directed against IRES sequences. The invention also provides genetically engineered expression vectors, host cells, transgenic animals, and transgenic plants comprising the novel inhibitory polynucleotides of the invention. The invention additionally provides methods of using the inhibitory polynucleotides of the invention.

Abstract: An embryonic stem cell line derived from a nucleus-transferred oocyte prepared by transferring a nucleus of a human somatic cell into an enucleated human oocyte may differentiate into various desired cell types.

Abstract: Methods of adapting cells, e.g., mammalian cells, to a cell culture process are provided. When the adapted cells are genetically modified and used for protein production, they exhibit beneficial characteristics, such as being able to attain higher cell densities and/or achieve a higher overall yield of the produced protein.

Abstract: The present invention relates to a pharmaceutical composition for the treatment of wounds containing blood plasma or serum and a method for treating wounds effectively by applying said composition to the wound site to normalize the tissue-environment around the site.

Abstract: The present invention relates to nucleic acid probes which are derived from rRNA genes of non-virus organisms and are useful for the detection of said non-virus infectious organisms in a biological sample. In addition, the present invention relates to compositions and chips useful for the diagnosis of one or more types of infectious diseases comprising said nucleic acid probes.

Abstract: The present invention provides an oligonucleotide array capable of identifying genes and related pathways involved with the induction of a particular phenotype by a cell line, e.g., the genes and related pathways involved with the induction of transgene expression by the cell line. The invention is particularly useful when there is little or no information about the genome of the cell line being studied, because it provides methods for identifying consensus sequences for known and previously undiscovered genes, and for designing oligonucleotide probes to the identified consensus sequences. Additionally, when the array is to be used to determine optimal conditions for expression of a transgene by the cell line, the invention teaches methods of including oligonucleotide probes to transgene sequences in the array. The invention also provides methods of using the array to identify genes and related pathways involved with the induction of a particular cell line phenotype.

Abstract: The present invention provides an oligonucleotide array capable of identifying genes and related pathways involved with the induction of a particular phenotype by a cell line, e.g., the genes and related pathways involved with the induction of transgene expression by the cell line. The invention is particularly useful when there is little or no information about the genome of the cell line being studied, because it provides methods for identifying consensus sequences for known and previously undiscovered genes, and for designing oligonucleotide probes to the identified consensus sequences. Additionally, when the array is to be used to determine optimal conditions for expression of a transgene by the cell line, the invention teaches methods of including oligonucleotide probes to transgene sequences in the array. The invention also provides methods of using the array to identify genes and related pathways involved with the induction of a particular cell line phenotype.

Abstract: The present invention relates to a pharmaceutical composition for the treatment of wounds containing blood plasma or serum and a method for treating wounds effectively by applying said composition to the wound site to normalize the tissue-environment around the site.

Abstract: Disclosed are methods of producing a cytokine antagonist polypeptide by co-expressing the cytokine antagonist polypeptide with a nucleic acid encoding a complexing polypeptide for the cytokine antagonist polypeptide.

Abstract: A pulsation dampener apparatus and method for dampening pulses within a fluid flow line during well drilling operations. The pulsation dampener apparatus comprises a cylindrical body having an annular chamber, a piston slidably disposed within the annular chamber, a gas column within the annular chamber and a means of communicating pulses from the fluid flow line to the piston. The piston is operated against the gas column to dampen the pulses within the fluid flow line.

Abstract: Method and system are disclosed for managing consumer feedback in an electronic content management system. The method and system of the invention includes a mechanism for consumers to provide feedback regarding the content that is published. The feedback is routed to the appropriate personnel responsible for publishing the content. In this way, the disconnect between what the consumer would like to see or cares about and the content that is published is closed. In addition, the consumer feedback triggers monitoring of the consumers content accessing activity, which allows the consumers consumption pattern to be tracked on an individual basis. This information may then be used to better define the content that get published in order to match the consumer's interests.

Abstract: A drilling jar comprising a mandrel with a shoulder extending radially outward. The shoulder defines at least one openable and closeable orifice therethrough. An outer housing is slidably disposed about the mandrel to define an upper chamber above the shoulder and a lower chamber below the shoulder. The jar also comprises a magnetorestriction material that responds to a predetermined pressure in the upper chamber to open at least one orifice in the shoulder to allow rapid pressure communication between the upper and lower chambers.

Abstract: The present invention relates to a metallic beverage end closure which is adapted to receive a drinking straw through a puncturable membrane in one embodiment, and which utilizes a hinged closure mechanism in another embodiment to provide access to a beverage stored in a container interconnected thereto.

Abstract: The present invention is directed to a content management system for receiving, editing, and distributing data across a network. The method includes accessing the data stored in a database, presenting the data for inspection, and assigning the data to at least one target location for distribution. Another embodiment of the present invention is a user interface operating on a computing device for editing data in the content management system.

Abstract: The present invention relates to a metallic beverage can end and more specifically to a substantially spillproof end which is adapted for penetration and opening by a drinking straw.

Abstract: A method of etching silicon using a plasma generated from a gas comprising fluorine (F), oxygen (O), hydrogen (H) and carbon (C).

Abstract: A beverage can end is provided herein which has a small opening preferably centrally disposed which is adapted for receiving a straw. Preferably, the small opening end is opened with a conventional pull tab, but which establishes a vent area positioned adjacent the small opening end which provides sufficient venting during use of the straw. It is further preferred that the pull tab be slightly elevated with rounded corners to provide a smooth, easily accessible pulling surface for the user of the beverage can.

Abstract: The present invention is directed to a content management system for receiving, editing, and distributing data across a network. The method includes accessing the data stored in a database, presenting the data for inspection, and assigning the data to at least one target location for distribution. Another embodiment of the present invention is a user interface operating on a computing device for editing data in the content management system.