Patents by Inventor George Fromm

George Fromm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10449233
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: October 22, 2019
    Assignee: Heat Biologics, Inc.
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva, Neal Schilling
  • Publication number: 20190169249
    Abstract: The present invention relates, in part, to, chimeric proteins which include the extracellular domain of colony stimulating factor 1 receptor (CSF1R) and their use in the treatment of diseases, such as immunotherapies for cancer and/or an inflammatory disease.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 6, 2019
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva
  • Publication number: 20190151413
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: November 28, 2018
    Publication date: May 23, 2019
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva
  • Patent number: 10188701
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 29, 2019
    Assignee: HEAT BIOLOGICS, INC.
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva
  • Patent number: 10183060
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: January 22, 2019
    Assignee: HEAT BIOLOGICS, INC.
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva
  • Publication number: 20190000967
    Abstract: Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among others, are provided herein. Materials and methods for using gp96-Ig vaccination and T-cell co-stimulation to treat a clinical condition (e.g., cancer) in a subject also are provided.
    Type: Application
    Filed: June 25, 2018
    Publication date: January 3, 2019
    Inventors: Taylor Schreiber, George Fromm
  • Publication number: 20180360955
    Abstract: Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among others, are provided herein. Materials and methods for using gp96-Ig vaccination and T-cell co-stimulation to treat a clinical condition (e.g., cancer) in a subject also are provided.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 20, 2018
    Inventors: Taylor Schreiber, George Fromm
  • Publication number: 20180326005
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 15, 2018
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva, Neal Schilling
  • Publication number: 20180326004
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 15, 2018
    Inventors: Taylor SCHREIBER, George FROMM, Suresh DE SILVA, Neal SCHILLING
  • Publication number: 20180326008
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 15, 2018
    Inventors: Taylor SCHREIBER, George FROMM, Suresh DE SILVA, Neal SCHILLING
  • Publication number: 20180326007
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 15, 2018
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva, Neal Schilling
  • Publication number: 20180326006
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: June 29, 2018
    Publication date: November 15, 2018
    Inventors: Taylor SCHREIBER, George FROMM, Suresh DE SILVA, Neal SCHILLING
  • Patent number: 10086042
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: October 2, 2018
    Assignee: Heat Biologics, Inc.
    Inventors: Taylor Schreiber, George Fromm, Suresh De Silva, Neal Schilling
  • Patent number: 10046047
    Abstract: Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among others, are provided herein. Materials and methods for using gp96-Ig vaccination and T-cell co-stimulation to treat a clinical condition (e.g., cancer) in a subject also are provided.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: August 14, 2018
    Assignee: Heat Biologics, Inc.
    Inventors: Taylor Schreiber, George Fromm
  • Publication number: 20180125935
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: December 22, 2017
    Publication date: May 10, 2018
    Inventors: Taylor SCHREIBER, George FROMM, Suresh DE SILVA, Neal SCHILLING
  • Publication number: 20180064787
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: November 6, 2017
    Publication date: March 8, 2018
    Inventors: Taylor SCHREIBER, George FROMM, Suresh DE SILVA, Neal SCHILLING
  • Publication number: 20170095531
    Abstract: The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
    Type: Application
    Filed: September 30, 2016
    Publication date: April 6, 2017
    Inventors: Taylor SCHREIBER, George FROMM, Suresh DE SILVA, Neal SCHILLING
  • Publication number: 20160250322
    Abstract: Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among others, are provided herein. Materials and methods for using gp96-Ig vaccination and T-cell co-stimulation to treat a clinical condition (e.g., cancer) in a subject also are provided.
    Type: Application
    Filed: February 5, 2016
    Publication date: September 1, 2016
    Inventors: Taylor Schreiber, George Fromm
  • Patent number: 7023174
    Abstract: A battery-operated vehicle, in particular to an industrial truck, includes an electronic control unit (2) and an on-board charging function. Instead of a separate charging unit, the invention teaches that the control unit (2) also regulates the charging function.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: April 4, 2006
    Assignee: STILL GmbH
    Inventors: Georg Fromme, Ansgar Bergmann, Marc Wede
  • Publication number: 20040017176
    Abstract: A battery-operated vehicle, in particular to an industrial truck, includes an electronic control unit (2) and an on-board charging function. Instead of a separate charging unit, the invention teaches that the control unit (2) also regulates the charging function.
    Type: Application
    Filed: March 18, 2003
    Publication date: January 29, 2004
    Inventors: Georg Fromme, Ansgar Bergmann, Marc Wede