Patents by Inventor George H. Smith

George H. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210318485
    Abstract: A variety of illumination devices are disclosed that are configured to manipulate light provided by one or more light-emitting elements (LEEs). In general, embodiments of the illumination devices feature one or more optical couplers that redirect illumination from the LEEs to a reflector which then directs the light into a range of angles. In some embodiments, the illumination device includes a second reflector that reflects at least some of the light from the first reflector. In certain embodiments, the illumination device includes a light guide that guides light from the collector to the first reflector. The components of the illumination device can be configured to provide illumination devices that can provide a variety of intensity distributions. Such illumination devices can be configured to provide light for particular lighting applications, including office lighting, task lighting, cabinet lighting, garage lighting, wall wash, stack lighting, and downlighting.
    Type: Application
    Filed: November 2, 2020
    Publication date: October 14, 2021
    Inventors: Wilson Dau, Robert C. Gardner, George Lerman, Louis Lerman, Christopher H. Lowery, Brian D. Ogonowsky, George E. Smith, Ingo Speier, Robert V. Steele, Jacqueline Teng, Allan Brent York, Hans Peter Stormberg
  • Patent number: 11124769
    Abstract: This disclosure provides methods of making a megakaryocyte-erythroid progenitor cell (MEP), comprising differentiating a MEP precursor cell into a MEP in culture in the presence of an aryl hydrocarbon receptor (AhR) modulator. In some embodiments the AhR modulator is an AhR antagonist. In some embodiments the AhR modulator is an AhR agonist. In some embodiments the methods comprise culturing MEP precursor cells in the presence of an AHR antagonist and then culturing MEP precursor cells in the presence of an AHR agonist. In some embodiments the stem cell is a pluripotent stem cell. In some embodiments the MEP co-expresses CD41 and CD235. In some embodiments the number of MEPs produced in the culture increases exponentially. Methods of making a red blood cell (RBC) by culturing a MEP in the presence of an AhR modulator are also provided. Methods of making a megakaryocyte and/or a platelet, comprising culturing a MEP in the presence of an AhR modulator are also provided.
    Type: Grant
    Filed: February 17, 2018
    Date of Patent: September 21, 2021
    Assignees: BOSTON MEDICAL CENTER CORPORATION, TRUSTEES OF BOSTON UNIVERSITY
    Inventors: George J. Murphy, David H. Sherr, Sarah S. Rozelle, Brenden W. Smith
  • Patent number: 11097272
    Abstract: According to an example, a microfluidic apparatus may include a fluid slot and a foyer that is in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer. The microfluidic apparatus may also include an electrical sensor to measure a change in an electrical field caused by a particle of interest in a fluid passing through the channel from the fluid slot to the foyer, an actuator to apply pressure onto fluid contained in the foyer, and a controller to receive the measured change in the electrical field from the electrical sensor, determine, from the received change in the electrical field, an electrical signature of the particle of interest, and control the actuator to control movement of the particle of interest based upon the determined electrical signature of the particle of interest.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: August 24, 2021
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Chantelle Domingue, Tod Woodford, Manish Giri, Matthew David Smith, George H Corrigan, III, Masoud Zavarehi, Joshua M. Yu
  • Patent number: 10856939
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: December 8, 2020
    Assignee: Covidien LP
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Publication number: 20190231422
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Application
    Filed: April 9, 2019
    Publication date: August 1, 2019
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Patent number: 10278776
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: May 7, 2019
    Assignee: COVIDIEN LP
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Publication number: 20160354145
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Application
    Filed: June 20, 2016
    Publication date: December 8, 2016
    Inventors: ROGER A. STERN, JEROME JACKSON, VINCENT N. SULLIVAN, GEORGE H. SMITH, ROY D. CORBITT, JENNIFER A. HODOR, CARSON J. SHELLENGBERGER
  • Patent number: 9393069
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: July 19, 2016
    Assignee: Covidien LP
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Publication number: 20150144641
    Abstract: A bunded tank system suitable for both transport and storage of bulk dangerous industrial liquids is provided. Preferably the tank is containerised to provide efficient use of space and improved logistics for transport and storage. The containerised bunded tank system includes a plurality of bunded sub-tanks arranged in an interlocking manner within an ISO container. In addition the container is fitted with an improved container lock.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 28, 2015
    Applicant: ETHANEX LIMITED
    Inventors: Robert M. Green, Nicholas G. Smith, George H. Smith
  • Publication number: 20120220996
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Application
    Filed: May 3, 2012
    Publication date: August 30, 2012
    Applicant: TYCO Healthcare Group LP
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Patent number: 8192426
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: June 5, 2012
    Assignee: TYCO Healthcare Group LP
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellenberger
  • Patent number: 7344535
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: March 18, 2008
    Assignee: Barrx Medical, Inc.
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Patent number: 7150745
    Abstract: Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member suach as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: December 19, 2006
    Assignee: BARRx Medical, Inc.
    Inventors: Roger A. Stern, Jerome Jackson, Vincent N. Sullivan, George H. Smith, Roy D. Corbitt, Jennifer A. Hodor, Carson J. Shellengberger
  • Publication number: 20040215296
    Abstract: A system for treating abnormal mucosa in an esophagus comprises an access catheter, an energy delivery structure near a distal end of the access catheter, and a power supply for delivering energy through the energy delivery structure under conditions which injure or ablate the mucosal layer of the esophageal wall without causing substantial injury or heating of the submucosal layer. By injuring or necrosing metaplastic or other abnormal mucosal cells, regrowth of the mucosa substantially free from abnormal cells can be initiated.
    Type: Application
    Filed: January 9, 2004
    Publication date: October 28, 2004
    Applicant: BARRx, Inc.
    Inventors: Robert A. Ganz, Brian D. Zelickson, Roger A. Stern, Jerome Jackson, George H. Smith
  • Patent number: 5103827
    Abstract: A method and apparatus for distinguishing ultrasound signals returned from bubbles and particles moving in a fluid from signals due to ultrasound transducer motion monitors the receiving ultrasound signal for signals which are of much larger amplitude than the signals observed when no gas bubbles or particles are present. When a large amplitude event is detected, the maximum amplitude of the forward flow signal (that is, the positive frequency portion of the power spectrum) is compared to the maximum amplitude of the reverse flow signal (negative frequency portion of the power spectrum). If these maxima are significantly different in amplitude, the event is counted as a bubble. If the maximum amplitudes of the forward and reverse flow signals are comparable, the event is classified as a motion artifact. Displays of the spectra are marked whenever an event is counted as an air or particulate emboli so as to call attention to the event and, optionally, to generate an audible or visual alarm.
    Type: Grant
    Filed: December 14, 1990
    Date of Patent: April 14, 1992
    Assignee: MedaSonics, Inc.
    Inventor: George H. Smith
  • Patent number: 4460677
    Abstract: A thermally developable imaging system comprises a leuco dye, nitrate ion, and a spectrally sensitized organic compound having photolyzable halogen atoms.
    Type: Grant
    Filed: November 8, 1982
    Date of Patent: July 17, 1984
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: George H. Smith, Peter M. Olofson
  • Patent number: 4394403
    Abstract: Photopolymerizable compositions which comprise cationically polymerizable organic material and photosensitive aromatic iodonium salt of a halogen-containing complex ion are described as are coated substrates and methods for bonding materials together using such compositions.
    Type: Grant
    Filed: April 2, 1975
    Date of Patent: July 19, 1983
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: George H. Smith
  • Patent number: 4386154
    Abstract: A thermally developable imaging system comprises a leuco dye, nitrate ion, and a spectrally sensitized compound selected from (1) aromatic iodonium salts and (2) compounds of photolyzable halogen atoms.
    Type: Grant
    Filed: March 26, 1981
    Date of Patent: May 31, 1983
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: George H. Smith, Peter M. Olofson
  • Patent number: 4378277
    Abstract: Photopolymerizable epoxy compositions which comprise an epoxy-containing material and photosensitive aromatic iondonium salt of a halogen-containing complex ion are described as are coated substrates and methods for bonding materials together using such compositions.
    Type: Grant
    Filed: March 10, 1978
    Date of Patent: March 29, 1983
    Assignee: Minnesota Mining & Manufacturing Company
    Inventor: George H. Smith
  • Patent number: 4329132
    Abstract: A system for plugging holes in vessels which comprises the combination of a storage and delivery system for a foam-forming material, and a hole-plugging assembly. The hole-plugging assembly includes a flexible nonelastic bag member which is inserted in a folded position into the hole to be plugged and properly positioned with an associated locating means. Thereafter, a unitary foamable material is injected into the bag member to expand it and seal the hole. The locating means further assists in maintaining the inflated bag member in proper orientation and sealing engagement while the foam is curing.
    Type: Grant
    Filed: October 6, 1980
    Date of Patent: May 11, 1982
    Assignee: Rockwell International Corporation
    Inventors: Robert W. Melvold, John J. Vrolyk, George H. Smith