Abstract: This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.

Abstract: A method and apparatus is provided to discover and integrate applications in an application router framework. The discovery operation includes receiving a registration notification for an application on a network, adding information describing the application to a repository into a data structure and publishing the data structure onto an application router. The association operations include querying one or more application routers on an application network for meta-data and other information on applications, exchanging the meta-data and other information between the application routers and associating the applications together automatically using their respective application protocols.

Abstract: This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.

Abstract: A pet food composition comprising a supplement. The supplement can include a glucose mimetic component. The supplement can include a glucose mimetic component that is a glucose anti-metabolite. The glucose anti-metabolite can be 2-deoxy-D-glucose, 5-thio-D-glucose, 3-O-methylglucose, anhydrosugars including 1,5-anhydro-D-glucitol, 2,5-anhydro-D-glucitol, 2,5-anhydro-D-mannitol, mannoheptulose, and/or avocado extract comprising mannoheptulose.

Abstract: The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.

Abstract: A method and system for restoring data on a production server by recovering individual data objects from a recovery storage group to a database residing on the production server. In one example method, a recovery interface accesses a recovery storage group containing a recovered database. The recovered database has been recovered from a backup storage location and contains a copy of a database residing on the production server. The method then identifies each data object residing in the recovery storage group and displays each of the data objects on a graphical user interface configured to allow a user to select and individual data objects for recovery from the recovered database. The selected data objects are restored to the appropriate location on the production server.

Abstract: A pet food composition comprising a supplement is provided. The supplement can comprise a Probiotic component, a cocoa butter component, and a sweetener component. A process for making the supplement can comprise providing a sweetener component, a cocoa butter component, and a Probiotic component, mixing the cocoa butter component and Probiotic component to form a mixture in a temperature and humidity controlled chamber; mixing the mixture with the sweetener component in the temperature and humidity controlled chamber to form a final mixture; optionally mixing in a colorant with the final mixture; and cooling the final mixture. A package for the supplement can comprise a secondary container housing a primary container, which houses a supplement. An array of packages is also provided.

Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

Abstract: Disclosed is an article of manufacture including bag having a front surface; a rear surface; two side surfaces each having a gusset therein and connecting the front and rear surfaces; a flattenable bottom surface formed by connecting the front, rear, and side surfaces; and a top surface formable by connecting the front, rear, and side surfaces. The bag has a height, a width, and a depth, and defines an internal volume. The bag is sealable and has a seal strength of at least about 1,600 pounds per square inch. The bag is formed from a plastic laminate having a thickness of from about 130 to about 200 microns and a tensile strength of at least about 3,400 pounds per square inch. The article of manufacture also includes at least about 15 pounds of a particulate, flowable composition contained therein. The bag can also have a closure system comprising a non-reusable closure and a reusable closure.

Abstract: Disclosed is an article of manufacture including bag having a front surface; a rear surface; two side surfaces each having a gusset therein and connecting the front and rear surfaces; a flattenable bottom surface formed by connecting the front, rear, and side surfaces; and a top surface formable by connecting the front, rear, and side surfaces. The bag has a height, a width, and a depth, and defines an internal volume. The bag is sealable and has a seal strength of at least about 1,600 pounds per square inch. The bag is formed from a plastic laminate having a thickness of from about 130 to about 200 microns and a tensile strength of at least about 3,400 pounds per square inch. The article of manufacture also includes at least about 15 pounds of a particulate, flowable composition contained therein. The bag can also have a closure system comprising a non-reusable closure and a reusable closure.