Abstract: The present disclosure is directed to methods of genetically subtypin peripheral t-cell lymphoma.

Abstract: Disclosed are methods for treating specific genetic subtypes of diffuse large B cell lymphoma using a combination of a BTK inhibitor and R-CHOP chemotherapy. The methods produce favorable event-free survival and overall survival rates among subjects exhibiting the genetic subtypes.

Abstract: An API generation system can be used to generate complete (or almost complete) APIs in response to received requests for new or modified APIs. Received API generation requests can include API descriptive data which is augmented to generate a set of data requirements defining one or more inputs and outputs for the API. The API functions can be mapped to one of a set of reference data models defining data types as used by the backend system, and the mappings used to automatically generate an API design defining input and output parameters for each API function of the requested API. The API generation system then assembles a code foundation for the requested API based on a set of software components implementing a portion of the API function and generates API source code based on the code foundation to complete the requested API.

Abstract: An API generation system can be used to generate complete (or almost complete) APIs in response to received requests for new or modified APIs. Received API generation requests can include API descriptive data which is augmented to generate a set of data requirements defining one or more inputs and outputs for the API. The API functions can be mapped to one of a set of reference data models defining data types as used by the backend system, and the mappings used to automatically generate an API design defining input and output parameters for each API function of the requested API. The API generation system then assembles a code foundation for the requested API based on a set of software components implementing a portion of the API function and generates API source code based on the code foundation to complete the requested API.

Abstract: An API generation system can be used to generate complete (or almost complete) APIs in response to received requests for new or modified APIs. Received API generation requests can include API descriptive data which is augmented to generate a set of data requirements defining one or more inputs and outputs for the API. The API functions can be mapped to one of a set of reference data models defining data types as used by the backend system, and the mappings used to automatically generate an API design defining input and output parameters for each API function of the requested API. The API generation system then assembles a code foundation for the requested API based on a set of software components implementing a portion of the API function and generates API source code based on the code foundation to complete the requested API.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopes after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: A health monitoring system is provided for a vehicle with an identity configured to travel on a surface. The system includes a body positioned on the surface and configured to stimulate a dynamic response from the vehicle as the vehicle travels over the body; a response sensor associated with the body and configured to measure the dynamic response from the vehicle; and an identification sensor associated with the body and configured to collect data corresponding to the identity of the vehicle.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: A health monitoring system is provided for a vehicle configured to travel over a surface with a velocity. The system includes a body configured to stimulate a dynamic response from the vehicle as the vehicle travels over the body; a response sensor associated with the body and configured to measure the dynamic response from the vehicle; an identification sensor associated with the body and configured to collect data corresponding to the identity of the vehicle; a velocity sensor associated with the body and configured to determine the velocity of the vehicle; and a processing unit associated with the body and configured to evaluate the health of the vehicle based on the dynamic response, the identity, and the velocity.

Abstract: The invention provides methods and materials related to a gene expression-based survival predictor for diffuse large B cell lymphoma (DLBCL) patients.

Abstract: Various embodiments comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include a usage detector and a disabling device coupled to the usage detector, wherein the disabling device is configured to disable the endoscope at least partly in response to an electrical, optical, and/or mechanical output from the usage detector.