Abstract: Systems and methods for focus control in a pan-tilt-zoom (PTZ) camera system are described herein. An example of a method described herein includes identifying a set of trace curves associated with the camera system, each of the trace curves specifying relationships between focus lens positions and zoom lens positions for a corresponding camera position, selecting a trace curve using the set of trace curves and one or more of pan angle, tilt angle or installation height of the camera system, and identifying a focus lens position for a current zooming factor of the camera system based on the selected trace curve.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: A method of measuring an anode current in an electron-multiplier device having an anode, a cathode, dynodes and a voltage divider network for applying voltages to the dynodes, which method includes applying an HV positive voltage to the anode and intermediate voltages to the dynodes, the cathode being at or near circuit ground potential, conducting dynode currents through or in parallel to the voltage divider to a point substantially at cathode potential, and deriving from those currents a current representative of the anode current.

Abstract: A method for facilitating comparison of image data from a given medical imaging protocol with archive image data, includes obtaining subject image data from a scan of a subject using the medical imaging protocol, obtaining archive image data differing from the subject image data in a given variable, determining a modifier usable to reduce the difference between the archive and subject image data, using the modifier to modify one of the subject image data and the archive image data to reduce the difference, and comparing the modified archive or subject image data with the subject or archive image data.

Abstract: In methods and an apparatus for generating a modified intensity projection image from captured medical image data of a subject, an intensity projection image data set and a secondary image data set are obtained from the image data. A region of interest is determined in the secondary image data set, and a surface of this region of interest is then determined. The intensity projection image data set and the region of interest surface are then combined to generate the modified intensity projection image for display.

Abstract: In a method and apparatus for establishing the position of one or more constituent elements of a phantom in an image quality test for a medical imaging apparatus, an image of the phantom is obtained, and a landmark pixel or region of the image determined. Values of a given variable at pixels or regions at a predetermined distance from the landmark pixel or region are determined. The landmark pixel or region and the values of the variable are then used to establish the position of one or more of the constituent elements of the phantom.

Abstract: In a method and apparatus for measuring a ratio of a variable for assessment in medical imaging data of a subject, a viewable image is generated from source imaging data of the subject. A pair of regions of interest for arrangement on the viewable image is then generated, and a value of the variable for each region of the pair from the source imaging data is determined. The ratio of the two values is then determined from the pair.

Abstract: A health monitoring system is provided for a vehicle with an identity configured to travel on a surface. The system includes a body positioned on the surface and configured to stimulate a dynamic response from the vehicle as the vehicle travels over the body; a response sensor associated with the body and configured to measure the dynamic response from the vehicle; and an identification sensor associated with the body and configured to collect data corresponding to the identity of the vehicle.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: A health monitoring system is provided for a vehicle configured to travel over a surface with a velocity. The system includes a body configured to stimulate a dynamic response from the vehicle as the vehicle travels over the body; a response sensor associated with the body and configured to measure the dynamic response from the vehicle; an identification sensor associated with the body and configured to collect data corresponding to the identity of the vehicle; a velocity sensor associated with the body and configured to determine the velocity of the vehicle; and a processing unit associated with the body and configured to evaluate the health of the vehicle based on the dynamic response, the identity, and the velocity.

Abstract: The invention provides methods and materials related to a gene expression-based survival predictor for diffuse large B cell lymphoma (DLBCL) patients.

Abstract: Disclosed are systems and methods for obtaining color endoscopic images with a monochromatic detector. In certain embodiments, such a monochromatic detector can provide beneficial features such as high resolution capability. In certain embodiments, a number of different color light sources can be controlled separately so as to allow sequential illumination of an object with the different color lights. Images obtained from such sequential illumination can be combined to yield a color image. Various configurations and examples for facilitating such a process are disclosed.

Abstract: Various embodiments comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include a usage detector and a disabling device coupled to the usage detector, wherein the disabling device is configured to disable the endoscope at least partly in response to an electrical, optical, and/or mechanical output from the usage detector.

Abstract: Disclosed are systems and methods involving an endoscope system having a plurality of different illumination sources. Such illumination sources can be controlled to provide various illumination effects. In certain embodiments, illumination sources can be controlled so that resulting outputs can be combined to yield, for example, an intensity profile that approximates a desired source such as a Xenon lamp. In certain embodiments, illumination sources can be activated in sequence so as to allow, for example, use of a monochromatic detector to generate a color image. In certain embodiments, illumination sources can be controlled so as to allow switching between two or more illumination modes.

Abstract: Various embodiments of the present invention comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include at least one solid state emitter such as a light emitting diode (LED) that is inserted into the body cavity to provide illumination therein. Certain embodiments of the invention comprise disposable endoscopes that can be fabricated relatively inexpensively such that discarding these endoscopses after a single use is cost-effective. The endoscope may comprise a lens holder on a distal end of the endoscope for collection of light reflected from surfaces within the body in which the endoscope is inserted. This lens holder may have an inner cavity through which light passes along an optical path. Reflective surfaces on sidewalls of the inner cavity may direct light along this optical path. The endoscope may further comprise an elongated support structure for supporting a plurality of lenses disposed along the optical path.

Abstract: A health monitoring system is provided for a vehicle with an identity configured to travel on a surface. The system includes a body positioned on the surface and configured to stimulate a dynamic response from the vehicle as the vehicle travels over the body; a response sensor associated with the body and configured to measure the dynamic response from the vehicle; and an identification sensor associated with the body and configured to collect data corresponding to the identity of the vehicle.

Abstract: An image processing method is described that allows a user to manipulate regions of interest (ROIs) in a mask based image. The user defines a stretch vector for example by ‘clicking and dragging’ a mouse pointer and an algorithm deforms the ROI according to a roll-off function that avoids the non-smooth edge effects seen in prior art techniques such as paintbrushes.

Abstract: In methods and an apparatus for generating a modified intensity projection image from captured medical image data of a subject, an intensity projection image data set and a secondary image data set are obtained from the image data. A region of interest is determined in the secondary image data set, and a surface of this region of interest is then determined. The intensity projection image data set and the region of interest surface are then combined to generate the modified intensity projection image for display.