Patents by Inventor Gerard Coquerel

Gerard Coquerel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid pharmaceutical composition containing 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta (C)chromen-3-yl sulfamate and polymorphs thereof
    Patent number: 8691281
    Abstract: The present invention relates to a solid pharmaceutical composition including the active principle 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate. The present invention also relates to polymorphs of the 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate compound.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: April 8, 2014
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Delphine Delahaye, Christian Diolez, Alain Rolland, Francis Diancourt, Gérard Coquerel, Damien Martins, Barry Victor Lloyd Potter, Lok Wai Lawrence Woo
  • SOLID PHARMACEUTICAL COMPOSITION CONTAINING 6-OXO-6,7,8,9,10,11-HEXAHYDROCYCLOHEPTA (C)CHROMEN-3-YL SULFAMATE AND POLYMORPHS THEREOF
    Publication number: 20140056977
    Abstract: The present invention relates to a solid pharmaceutical composition including the active principle 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate. The present invention also relates to polymorphs of the 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate compound.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 27, 2014
    Applicant: Ipsen Pharma S.A.S.
    Inventors: Nathalie MONDOLY, Bertrand Poirot, Anne Brochard, Joël Richard, Delphine Delahaye, Christian Diolez, Alain Rolland, Francis Diancourt, Gérard Coquerel, Damien Martins, Julie Linol, Ophélie Houssin, Marie-Noêlle Petit, Barry, Victor, Lloyd Potter, Lok, Wai Lawrence Woo
  • Precursor phase and use thereof for preparing the magnesium tetrahydrate salt of an omeprazole enantiomer
    Patent number: 8592601
    Abstract: A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: November 26, 2013
    Assignees: Produits Chimiques Auxiliaires et de Synthese, Universite de Rouen
    Inventors: Snella Chouippe, Jean-Marie Schneider, Guillaume Tauvel, Gerard Coquerel
  • Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-?-L-ribofuranosyl)-1H-benzimidazole
    Patent number: 8546344
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: October 1, 2013
    Assignee: ViroPharma Incorporated
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • Conglomerates of tenatoprazole potassium salts
    Patent number: 8546574
    Abstract: The invention relates to conglomerates of tenatoprazole potassium salts of the following general formula (I), that consist of an equimolar mixture of enantiomers having R and S configurations and capable of crystallization in the form of a conglomerate, wherein said salts are selected from tenatoprazole dehydrated potassium salt, tenatoprazole potassium dimethanolate, tenatoprazole potassium diethanolate and tenatoprazole potassium ethylene-glycolate. The invention also relates to a pharmaceutical composition containing such salt, and to the use of said salt.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: October 1, 2013
    Assignee: Sidem Pharma SA
    Inventors: Avraham Cohen, François Schutze, Suzy Charbit, Stéphane Bernad, Guillaume Tauvel, Marie-Noëlle Petit, Gérard Coquerel
  • METHOD FOR THE PREPARATION OF (3S, 3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID)
    Publication number: 20130231500
    Abstract: The present invention relates to a new method for the preparation of (3S,3S?) 4,4?-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
    Type: Application
    Filed: October 7, 2011
    Publication date: September 5, 2013
    Applicant: QUANTUM GEOMICS
    Inventors: Fabrice Balavoine, Jonathan Madec, Jean-Marie Schneider, Gérard Coquerel, Nicolas Couvrat, Yohann Cartigny, Marie-Noëlle Petit
  • SOLID PHARMACEUTICAL COMPOSITION CONTAINING 6-OXO-6,7,8,9,10,11-HEXAHYDROCYCLOHEPTA (C)CHROMEN-3-YL SULFAMATE AND POLYMORPHS THEREOF
    Publication number: 20120321714
    Abstract: The present invention relates to a solid pharmaceutical composition including the active principle 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate. The present invention also relates to polymorphs of the 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate compound.
    Type: Application
    Filed: March 26, 2012
    Publication date: December 20, 2012
    Applicant: Ipsen Pharma S.A.S.
    Inventors: Nathalie MONDOLY, Bertrand Poirot, Anne Brochard, Joël Richard, Delphine Delahaye, Christian Diolez, Alain Rolland, Francis Diancourt, Gérard Coquerel, Damien Martins, Julie Linol, Marie-Noêlle Petit, Barry Victor Llyod Potter, Lok, Wai Lawrence Woo
  • PROCESS FOR THE RESOLUTION OF ENANTIOMERS BY PREFERENTIAL EVAPORATIVE CRYSTALLIZATION
    Publication number: 20120259127
    Abstract: A process for the resolution of two enantiomers which involves inducing the preferential crystallization of one enantiomer by adjusting the composition of a suspension or solution including a racemic mixture of the two enantiomers and a solvent, by evaporation of the latter.
    Type: Application
    Filed: December 16, 2010
    Publication date: October 11, 2012
    Applicant: UNIVERSITE DE ROUEN
    Inventors: Gerard Coquerel, Guillaume Levilain
  • Process for obtaining the crystalline form V of agomelatine
    Patent number: 8252957
    Abstract: Process for obtaining the crystalline form V of the compound of formula (I):
    Type: Grant
    Filed: August 4, 2009
    Date of Patent: August 28, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Damien Martins, Gerard Coquerel, Julie Linol, Pascal Langlois
  • CRYSTALLINE PHASES OF 5,6-DFICHLORO-2-(ISOPROPYLAMINO)-1-ß-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE
    Publication number: 20120178709
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Application
    Filed: October 27, 2011
    Publication date: July 12, 2012
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5, TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION
    Publication number: 20120071655
    Abstract: A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.
    Type: Application
    Filed: March 26, 2010
    Publication date: March 22, 2012
    Inventors: Matthias Helmreich, Claus-Peter Niesert, Daniel Cravo, Gérard Coquerel, Gullaume Levilain, Saoussen Wacharine-Antar, Pascal Cardinael
  • Crystalline form VI of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 8067639
    Abstract: Crystalline form VI of the compound of formula (I): characterised by its X-ray powder diffraction diagram. Medicinal products containing the same which are useful in treating melatoninergic disorders.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: November 29, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Gerard Coquerel, Julie Linol, Lionel Le Pape, Jean-Pierre Lecouve
  • PRECURSOR PHASE AND USE THEREOF FOR PREPARING THE MAGNESIUM TETRAHYDRATE SALT OF AN OMEPRAZOLE ENANTIOMER
    Publication number: 20110269798
    Abstract: A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.
    Type: Application
    Filed: March 31, 2011
    Publication date: November 3, 2011
    Applicants: UNIVERSITE DE ROUEN, PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE
    Inventors: Snella CHOUIPPE, Jean-Marie SCHNEIDER, Guillaume TAUVEL, Gerard COQUEREL
  • Method for resolving omeprazole salts
    Patent number: 8034948
    Abstract: The present invention relates to the resolution by preferential crystallization of potassium salts of racemic omeprazole which is a solvate of ethanol and/or of ethylene glycol, which consists in converting the omeprazole to the potassium salt in the form of a solvate or of a mixture of these solvates in the presence of an excess of inorganic base which is a source of potassium, the said potassium salts existing in the form of conglomerates, and in then resolving the said conglomerates, independently or simultaneously, by preferential crystallization in order to separate the two (S) and (R) enantiomers of these potassium salts of omeprazole.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: October 11, 2011
    Assignee: Universite de Rouen
    Inventors: Gérard Coquerel, Guillaume Tauvel, Marie-Noelle Petit
  • NOVEL POLYMORPHIC FORM OF CHDMAPP, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
    Publication number: 20110245534
    Abstract: The present invention relates to novel polymorphs of (2E)-1-hydroxy-2-methylpent-2-enyl-pyrophosphonate disodium (CHDMAPP-Na2), to the process for preparing them and to the pharmaceutical compositions containing them.
    Type: Application
    Filed: September 8, 2009
    Publication date: October 6, 2011
    Applicant: Innate Pharma
    Inventors: Guillaume Descamps, Youness Amharar, Yohann Cartigny, Gérard Coquerel
  • Crystalline form III of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7939566
    Abstract: Crystalline form III of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: May 10, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Gerard Coquerel, Julie Linol, Jean-Claude Souvie
  • ? Crystalline form of the arginine salt of perindopril, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7923569
    Abstract: ?-crystalline form of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as inhibitors of angiotensin I converting enzyme.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: April 12, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Gérard Coquerel, Loïc Lefebvre, Jean-Claude Souvie, Pascale Authouart
  • Crystalline form IV of agomelatine, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7910625
    Abstract: Crystalline form IV of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: March 22, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Gerard Coquerel, Julie Linol, Jean-Claude Souvie
  • CONGLOMERATES OF TENATOPRAZOLE POTASSIUM SALTS
    Publication number: 20110060002
    Abstract: The invention relates to conglomerates of tenatoprazole potassium salts of the following general formula (I), that consist of an equimolar mixture of enantiomers having R and S configurations and capable of crystallisation in the form of a conglomerate, wherein said salts are selected from tenatoprazole dehydrated potassium salt, tenatoprazole potassium dimethanolate, tenatoprazole potassium diethanolate and tenatoprazole potassium ethylene-glycolate. The invention also relates to a pharmaceutical composition containing such salt, and to the use of said salt.
    Type: Application
    Filed: December 3, 2007
    Publication date: March 10, 2011
    Applicant: SIDEM PHARAMA SA
    Inventors: Avraham Cohen, Francois Schutze, Suzy Charbit, Stéphane Bernad, Cuillaume Tauvel, Marie-Noëlle Petit, Gérard Coquerel
  • ? crystalline form of the arginine salt of perindopril, a process for its preparation and pharmaceutical compositions containing it
    Patent number: 7846961
    Abstract: ?-crystalline form of the compound of formula (I): characterized by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as inhibitors of angiotensin I converting enzyme.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: December 7, 2010
    Assignee: Les Laboratoires Servier
    Inventors: Gérard Coquerel, Loïc Lefebvre, Jean-Claude Souvie, Pascale Authouart