Patents by Inventor Gerard Coquerel

Gerard Coquerel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6992219
    Abstract: Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: January 31, 2006
    Assignees: Cephalon France, Organisation de Synthese Mondiale Orsymonde
    Inventors: Véronique Broquaire, legal representative, Ludovic Broquaire, legal representative, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet, Michel Broquaire, deceased
  • Publication number: 20050203165
    Abstract: A ? crystalline form of the compound of formula (I): characterized by its powder X-ray diffraction data. Medicinal products containing the same which are useful as inhibitors of angiotensin I converting enzyme.
    Type: Application
    Filed: February 4, 2005
    Publication date: September 15, 2005
    Applicant: LES LABORATORIES SERVIER
    Inventors: Bruno Pfeiffer, Yves-Michel Ginot, Gerard Coquerel, Stephane Beilles
  • Publication number: 20050059609
    Abstract: An ? crystalline form of the compound of formula (I): characterized by its powder X-ray diffraction data. Medicinal products containing the same which are useful as inhibitors of angiotensin I converting enzyme.
    Type: Application
    Filed: March 3, 2004
    Publication date: March 17, 2005
    Inventors: Bruno Pfeiffer, Yves-Michel Ginot, Gerard Coquerel, Stephane Beilles
  • Publication number: 20040248817
    Abstract: A &ggr; crystalline form of the compound of formula (I): 1
    Type: Application
    Filed: March 29, 2004
    Publication date: December 9, 2004
    Inventors: Bruno Pfeiffer, Yves-Michel Ginot, Gerard Coquerel, Stephane Beilles
  • Patent number: 6767921
    Abstract: The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylpropionyl-amino)propionate, hereinafter called Fasidotril, their methods of preparation and novel pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: July 27, 2004
    Assignee: Bioproject
    Inventors: Marc Capet, Gérard Coquerel, Denis Danvy, Jeanne-Marie Lecomte, Marie-Noëlle Petit, Jean-Charles Schwartz
  • Publication number: 20040102523
    Abstract: Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
    Type: Application
    Filed: August 7, 2003
    Publication date: May 27, 2004
    Inventors: Michel Broquaire, Laurent Courvoisier, Armand Frydman, Gerard Coquerel, Franck Mallet, Veronique Broquaire, Ludovic Broquaire
  • Publication number: 20040029813
    Abstract: &bgr; crystalline form of the compound of formula (I): 1
    Type: Application
    Filed: December 31, 2002
    Publication date: February 12, 2004
    Inventors: Bruno Pfeiffer, Yves-Michel Ginot, Gerard Coquerel, Stephane Beilles
  • Publication number: 20030203965
    Abstract: The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylpropionyl-amino)propionate, hereinafter called Fasidotril, their methods of preparation and novel pharmaceutical compositions containing them.
    Type: Application
    Filed: March 26, 2003
    Publication date: October 30, 2003
    Inventors: Marc Capet, Gerard Coquerel, Denis Danvy, Jeanne-Marie Lecomte, Marie-Noelle Petit, Jean-Charles Schwartz
  • Publication number: 20030186896
    Abstract: &agr; crystalline form of the compound of formula (I): 1
    Type: Application
    Filed: December 31, 2002
    Publication date: October 2, 2003
    Inventors: Bruno Pfeiffer, Yves-Michel Ginot, Gerard Coquerel, Stephane Beilles
  • Publication number: 20030158121
    Abstract: &ggr; crystalline form of the compound of formula (I): 1
    Type: Application
    Filed: December 31, 2002
    Publication date: August 21, 2003
    Inventors: Bruno Pfeiffer, Yves-Michel Ginot, Gerard Coquerel, Stephane Beilles
  • Patent number: 6316671
    Abstract: This invention relates to a method of splitting 1-amino-alkan-2-ol compounds of general formula: in which the group R can represent a wide variety of linear, branched or cyclic alkyl groups, comprising up to about 20 to 25 carbon atoms and preferably 1 to 15 carbon atoms. These groups can possibly have one or more double bonds, one or more hetero-atoms such as oxygen or sulfur so long as these are to be found separated from the asymmetric carbon atom by at least one carbon link and do not destroy the aliphatic nature of the group R. These groups can also be substituted by one or more halogen atoms such as chlorine or lower alkoxy groups such as methoxy or ethoxy groups.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: November 13, 2001
    Assignee: Universite de Rouen
    Inventors: Gerard Coquerel, Lionel Catroux, Yvette Combret
  • Patent number: 6022409
    Abstract: A method of optical enantiomer resolution by preferential crystallization involves entering, each time crystallization starts, the two-phase domain containing excess enantiomer and the saturated solution, and cooling according to a well-defined kinetic schedule. A racemic mixture of fine particle size is added to the mother liquors obtained after harvesting the crystals, the mother liquors then being heated to a temperature lower than that of homogenization of the solution so that excess enantiomer is present only in a solid state in equilibrium with the solution. Further cooling produces the other enantiomer and completes the cycle of operations which may then be carried out repetitively.
    Type: Grant
    Filed: October 2, 1996
    Date of Patent: February 8, 2000
    Assignee: The University of Rouen
    Inventors: Gerard Coquerel, Marie-Noelle Petit, Roger Bouaziz
  • Patent number: 5326878
    Abstract: Method of resolution of chiral hydantoins of the general formula I ##STR1## in which: R.sub.1 designates a lower alkyl radical comprising 1 to 5 carbon atoms in linear or branched chain,R.sub.2 designates a phenyl radical, possibly mono-, di-, or tri-substituted by lower alkyl or alkoxy radicals or halogen atoms, whether identical of different, or a heteroaryl radical containing a ring of 5 to 7 members in which the sole hetero atom is nitrogen, oxygen or sulfur, or else an aralkyl radical the alkyl part of which comprises one or two carbon atoms and the aryl ring is a phenyl group possibly mono-, di- or tri-substituted by radicals which are lower alkyl or alkoxy radicals or halogen atoms, whether identical or different. The hydantoin (I) to be resolved is dissolved in an alcohol or an alkaline solution, and an enantiomer of .alpha.
    Type: Grant
    Filed: July 21, 1992
    Date of Patent: July 5, 1994
    Assignee: Jouveinal SA
    Inventors: Dominique Depernet, Roger Bouaziz, Gerard Coquerel, Marie N. Petit