Patents by Inventor Gerard Mathis

Gerard Mathis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers
    Patent number: 5346996
    Abstract: The invention relates to rare earth cryptates consisting of at least one rare earth salt complexed by a macropolycyclic compound corresponding to one of formulae I or II below, in which:the ring ##STR1## is the N.sub.2 O.sub.4 macrocycle, the N.sub.2 O.sub.3 macrocycle or the bis-bipyridine macrocycle;Y is a spacer arm or group which consists of a divalent organic radical selected from linear or branched C.sub.1 to C.sub.20 alkylene groups optionally containing one or more double bonds and/or optionally being interrupted by one or more heteroatoms such as oxygen, nitrogen, sulfur or phosphorus, or from C.sub.5 to C.sub.8 cycloalkylene groups or C.sub.6 to C.sub.14 arylene groups, the said alkylene or arylene groups optionally being substituted by alkyl, aryl or sulfonate groups;Z is a functional group capable of bonding covalently with a biological substance;R is a methyl group or represents the group --Y--Z; andR' is hydrogen or a group --COOR", in which R" is a C.sub.1 to C.sub.
    Type: Grant
    Filed: September 14, 1992
    Date of Patent: September 13, 1994
    Assignee: Compagnie Oris Industrie
    Inventors: Jean-Marie Lehn, Gerard Mathis, Beatrice Alpha, Robert Deschenaux, Etienne Jolu
  • Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present
    Patent number: 5279943
    Abstract: The present invention relates to a homogeneous process for the detection and/or determination of an analyte in a medium in which it may be present, by disclosing the reaction product of the analyte and a corresponding receptor, process consisting in: 1) adding to said medium a first reagent consisting of a receptor for the said analyte; 2) adding a second reagent consisting of at least one of the components of the reaction product of the analyte and at least one of its receptors; one of the two reagents being coupled with a luminescent compound and the other reagent possessing a heavy atom or units containing a heavy atom; 3) incubating the medium after addition of each reagent or after the addition of both reagents; 4) exciting the resulting medium and 5) measuring at equilibrium or during the kinetics, the signal emitted by the luminescent compound, said signal being modulated by the heavy atom effect.
    Type: Grant
    Filed: January 19, 1993
    Date of Patent: January 18, 1994
    Assignee: Compagnie Oris Industrie
    Inventors: Gerard Mathis, Thierry Davin
  • Macropolycyclic rare earth complexes and application as fluorescent tracers
    Patent number: 5220012
    Abstract: The invention relates to macropolycyclic rare earth complexes, namely cryptates which are useful as fluorescent tracers.
    Type: Grant
    Filed: March 5, 1990
    Date of Patent: June 15, 1993
    Assignee: Compagnie Oris Industrie SA
    Inventors: Gerard Mathis, Jean-Marie Lehn
  • Macropolycyclic rare earth complexes and application as fluorescent tracers
    Patent number: 4927923
    Abstract: The invention relates to macropolycyclic rare earth complexes, namely cryptates which are useful as fluorescent tracers.
    Type: Grant
    Filed: September 20, 1985
    Date of Patent: May 22, 1990
    Assignee: Compagnie Oris Industries
    Inventors: Gerard Mathis, Jean-Marie Lehn