Patents by Inventor Gerard Moinet

Gerard Moinet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF TRAZINE DERIVATIVES AND INSULIN SECRETION STIMULATORS
    Publication number: 20100233255
    Abstract: The present patent application relates to novel combinations of a triazine derivative and of an insulin secretion stimulator.
    Type: Application
    Filed: December 18, 2006
    Publication date: September 16, 2010
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Patent number: 7767676
    Abstract: The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 3, 2010
    Assignee: Merck Sante
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • USE OF TRIAZINE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT HAVING A CICATRISING OR ANGIOGENIC EFFECT
    Publication number: 20100168115
    Abstract: The present patent application relates to the use of triazine derivatives as cicatrising or angiogenic agents, wherein the triazine is a molecule of formula (I).
    Type: Application
    Filed: December 18, 2006
    Publication date: July 1, 2010
    Inventors: Gérard Moinet, Daniel Cravo
  • COMBINATION OF TRIAZINE DERIVATIVES AND HMG-COA REDUCTASE INHIBITORS
    Publication number: 20100158999
    Abstract: The present patent application relates to combinations of a triazine derivative with an HMG-CoA reductase inhibitor.
    Type: Application
    Filed: December 18, 2006
    Publication date: June 24, 2010
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau
  • COMBINATION OF TRIAZINE DERIVATIVES AND PPARalpha AGONISTS
    Publication number: 20100159005
    Abstract: The present patent application relates to combinations of triazine derivatives and of PPAR? agonists.
    Type: Application
    Filed: December 18, 2006
    Publication date: June 24, 2010
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau
  • Kynurenine 3-hydroxylase inhibitors for the treatment of diabetes
    Patent number: 7727977
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: June 1, 2010
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Gérard Moinet, Dominique Mariais, Catherine Kargar, Micheline Kergoat
  • USE OF AMPK-ACTIVATING IMIDAZOLE DERIVATIVES, PREPARATION PROCESS THEREFOR AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
    Publication number: 20090253764
    Abstract: The invention relates to the use of imidazole derivatives of the formula (1): in which A, R?1, R?2 and R?3 are as defined in the description, as AMPK activators. The invention also relates to processes for the preparation of the said compounds, to their uses for the preparation of medicaments for the treatment of insulin resistance, diabetes and related pathologies, and also obesity, and to the pharmaceutical compositions comprising them. Certain compounds of the formula (1) are novel and, in this respect, also form part of the invention.
    Type: Application
    Filed: June 12, 2007
    Publication date: October 8, 2009
    Inventors: Gerard Moinet, Dominique Marais, Sophie Hallakou-Bozec, Christine Charon
  • Process for resolving aimines that are useful for the treatment of disorders associated with insulin resistance syndrome
    Patent number: 7501511
    Abstract: The present invention is directed towards a process for resolving a racemic amino compound derived from dihydro-1,3,5-triazines. The invention is also directed towards the enantiomers of amino derivatives of dihydro-1,3,5-triazines and to their use for the preparation of medicaments, in particular for the treatment of diabetes and malaria.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: March 10, 2009
    Assignee: Merck Patent GmbH
    Inventors: Gérard Moinet, Daniel Cravo, Thierry Passemar
  • Bicyclic guanidine derivatives and therapeutic uses thereof
    Patent number: 7491733
    Abstract: The invention relates to compounds of general formula (I), in which A, X, Y and R1 are defined in Claim 1. These compounds may be used in the treatment of pathologies associated with insulin resistane syndrome.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: February 17, 2009
    Assignee: Merck Patent GmbH
    Inventors: Gerard Moinet, Daniel Cravo
  • Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies
    Patent number: 7470708
    Abstract: The invention relates to compounds of the general formula (I): in which R1, R2, X, and A are as defined in claim 1. These compounds can be used in the treatment of hyperglycaemia-related pathologies.
    Type: Grant
    Filed: December 1, 2004
    Date of Patent: December 30, 2008
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventors: Gérard Moinet, Jean-Claude Correc, Annick Arbellot De Vacueur
  • Imidazole Derivatives as Fructose-1,6-Bisphosphatase Inhibitors and Pharmaceutical Compositions Containing Them
    Publication number: 20080312299
    Abstract: Imidazole derivatives of formula (I) wherein R1, R2a, R2b, A, V and W are as defined in the description, as inhibitors of fructose-1,6-bisphosphatase, their preparation process and their use in the prevention or treatment of diabetes, and other diseases where the inhibition of gluconeogenesis, control of blood glucose levels, reduction in glycogen stores, or reduction in insulin levels is beneficial and diseases related to the insulin resistance syndrome.
    Type: Application
    Filed: July 19, 2006
    Publication date: December 18, 2008
    Inventors: Denis Carniato, Gerard Moinet, Gerard Botton, Annick Arbellot De Vacqueur, Annick Audet
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Patent number: 7452883
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. The compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: November 18, 2008
    Assignee: Merck Sante
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Novel Imidazolecarboxamide Derivatives as Fructose-1,6-Bisphosphatase Inhibitors, and Pharmaceutical Compositions Comprising Same
    Publication number: 20080207720
    Abstract: The invention relates to the compounds of the general formula (I): in which A, D, R, R1 and X are as defined in the description, to a process for the preparation thereof and to the therapeutic use thereof in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Application
    Filed: July 7, 2006
    Publication date: August 28, 2008
    Inventors: Gerard Moinet, Gerard Botton, Annick Arbellot de Vacqueur
  • Antidiabetic compounds comprising benzofuran and benzothiophene derivatives
    Patent number: 7375130
    Abstract: The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in claim 1. These compounds can be used in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Grant
    Filed: October 26, 2004
    Date of Patent: May 20, 2008
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Gérard Moinet, Caroline Leriche, Micheline Kergoat
  • Benzofurans and benzothiophenes
    Patent number: 7371774
    Abstract: The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in claim 1. These compounds can be used in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: May 13, 2008
    Assignee: Merck Patent GmbH
    Inventors: Gérard Moinet, Caroline Leriche, Micheline Kergoat
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20080108591
    Abstract: The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Applicant: MERCK SANTE
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20080108619
    Abstract: The invention relates to the compounds of general formula (I): in which R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. These compounds can be used in the treatment of pathological conditions associated with the insulin-resistance syndrome.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 8, 2008
    Applicant: MERCK SANTE
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes
    Publication number: 20080045483
    Abstract: The invention relates to compounds of general formula (1): in which R1, R2, R3, R4, R5, A, B, D and E are as defined in Claim 1, and also to the preparation process therefor and the therapeutic use thereof. These compounds can be used in the treatment of pathologies associated with hyperglycaemia.
    Type: Application
    Filed: June 1, 2005
    Publication date: February 21, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Gerard Moinet, Gerard Botton, Micheline Gergoat
  • Biguanide derivatives
    Patent number: 7285681
    Abstract: The present invention relates to biguanide derivatives of formula (I), wherein R1, R2, R3 and R4 have the meanings as given in claim (1). Compounds are useful in the treatment of pathologies associated with hyperglycaemia, such as diabetes.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: October 23, 2007
    Assignee: Merck Patent Gesellschaft
    Inventors: Gerard Moinet, Daniel Cravo
  • Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies
    Publication number: 20070149566
    Abstract: The invention relates to compounds of the general formula (I): in which R1, R2, X, and A are as defined in claim 1. These compounds can be used in the treatment of hyperglycaemia-related pathologies.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 28, 2007
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHARENKTER HAFTUNG
    Inventors: Gerard Moinet, Jean-Claude Correc, Annick Arbellot De Vacuer