Patents by Inventor Gerard Moinet

Gerard Moinet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antidiabetic compounds comprising benzofuran and benzothiophene derivatives
    Publication number: 20070078178
    Abstract: The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in Claim 1. These compounds can be used in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Application
    Filed: October 26, 2004
    Publication date: April 5, 2007
    Inventors: Gerard Moinet, Caroline Leriche, Micheline Kergoat
  • Benzofurans and benzothiophenes
    Publication number: 20070066680
    Abstract: The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in claim 1. These compounds can be used in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Application
    Filed: November 8, 2004
    Publication date: March 22, 2007
    Inventors: Gerard Moinet, Caroline Leriche, Micheline Kergoat
  • Process for resolving aimines that are useful for the treatment of disorders associated with insulin resistance syndrome
    Publication number: 20060223803
    Abstract: The present invention is directed towards a process for resolving a racemic amino compound derived from dihydro-1,3,5-triazines. The invention is also directed towards the enantiomers of amino derivatives of dihydro-1,3,5-triazines and to their use for the preparation of medicaments, in particular for the treatment of diabetes and malaria.
    Type: Application
    Filed: April 6, 2004
    Publication date: October 5, 2006
    Inventors: Gérard Moinet, Daniel Cravo, Thierry Passemar
  • Kynurenine 3-hydroxylase inhibitors for the treatment of diabetes
    Publication number: 20060142358
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase for the preparation of a medicament for the prevention and/or treatment of diabetes.
    Type: Application
    Filed: December 18, 2003
    Publication date: June 29, 2006
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Micheline Kergoat, Gerard Moinet, Dominique Marais, Catherine Kargar
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Patent number: 7034021
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. Said compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: April 25, 2006
    Assignee: LIPHA
    Inventors: Gérard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Kynurenine 3-hydroxylase inhibitors for the treatment of diabetes by increasing the number of islets of langerhans cells
    Publication number: 20060052456
    Abstract: The present invention relates to the use of at least one compound with inhibitory activity on kynurenine 3-hydroxylase, for the preparation of a medica ment for increasing the number of islets of Langerhans cells, which is intended especially for the prevention and/or treatment of diabetes.
    Type: Application
    Filed: December 18, 2003
    Publication date: March 9, 2006
    Applicant: MERCK PATENT GMBH
    Inventors: Valerie Autier, Annick Arbellot De Vacqueur, Micheline Kergoat, Gerard Moinet, Dominique Marais, Catherine Kargar
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20050165022
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in Claim 1. The compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Application
    Filed: March 22, 2005
    Publication date: July 28, 2005
    Applicant: LIPHA
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Pharmaceutical composition comprising a glitazone and a 4-oxobutanoic acid, and the use thereof for treating diabetes
    Publication number: 20050085489
    Abstract: The present invention relates to a pharmaceutical composition comprising, as active principles, a 4-oxobutanoic acid and a glitazone, in combination with one or more pharmaceutically acceptable excipients. These compositions are particularly suitable for treating diabetes.
    Type: Application
    Filed: December 16, 2002
    Publication date: April 21, 2005
    Inventor: Gerard Moinet
  • Pharmaceutical composition comprising an alpha-glucosidase inhibitor and a 4-oxobutanoic acid, and the use thereof for treating diabetes
    Publication number: 20050070553
    Abstract: The present invention relates to a pharmaceutical composition comprising, as active principles, a 4-oxobutanoic acid and an ?-glucosidase inhibitor, in combination with one or more pharmaceutically acceptable excipients. These compositions are particularly suitable for treating diabetes.
    Type: Application
    Filed: December 7, 2002
    Publication date: March 31, 2005
    Inventors: Gerard Moinet, Dominique Marais
  • Use of 4-oxobutanoic acid derivatives in the treatment of inflammation
    Publication number: 20050014768
    Abstract: The present invention relates to the use of a 4-oxobutanoic acid derivative for the preparation of a pharmaceutical composition for treating inflammation.
    Type: Application
    Filed: November 6, 2002
    Publication date: January 20, 2005
    Inventors: Gerard Moinet, Dominique Marais, Philippe Maizeray
  • Bicyclic guanidine derivatives and therapeutic uses thereof
    Publication number: 20040122040
    Abstract: The invention relates to compounds of general formula (I), in which A, X, Y and R1 are delined in claim 1. These compounds may be used in the treatment of pathologies associated with insulin resistane syndrome.
    Type: Application
    Filed: September 22, 2003
    Publication date: June 24, 2004
    Inventors: Gerard Moinet, Daniel Cravo
  • Pharmaceutical composition
    Publication number: 20040097567
    Abstract: The invention relates to a pharmaceutical compositions for the treatment of diabetes comprising, as active principles, a derivation of the 5-phenoxyalkyl-2,4-thiazolidinedione type and a compound that stimulates insulin secretion.
    Type: Application
    Filed: September 17, 2003
    Publication date: May 20, 2004
    Inventors: Gerard Moinet, Gerard Botton, Didier Mesangau
  • Biguanide derivatives
    Publication number: 20040092495
    Abstract: The present invention relates to biguanide derivatives of formula (I), wherein R1, R2, R3 and R4 have the meanings as given in claim (1). Compounds are useful in the treatment of pathologies associated with hyperglycaemia, such as diabetes.
    Type: Application
    Filed: September 22, 2003
    Publication date: May 13, 2004
    Inventors: Gerard Moinet, Daniel Cravo
  • Pharmaceutical composition comprising metformin and a 5-phenoxyalkyl-2,4-thiazolidinedione-type derivative
    Publication number: 20040014797
    Abstract: The present invention relates to a pharmaceutical composition comprising, as active ingredients, metformin optionally in the form of one of its pharmaceutically acceptable salts and a 5-phenoxyalkyl-2,4-thiazolidinedione-type derivative.
    Type: Application
    Filed: February 3, 2003
    Publication date: January 22, 2004
    Inventors: Gerard Moinet, Gerard Botton, Didier Mesangeau
  • Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
    Publication number: 20030109530
    Abstract: The invention concerns compounds of general formula (I) wherein: R1, R2, R3, R4, R5 and R6 are as defined in claim 1. Said compounds are useful in the treatment of pathologies related to the insulin-resistance syndrome.
    Type: Application
    Filed: July 15, 2002
    Publication date: June 12, 2003
    Inventors: Gerard Moinet, Daniel Cravo, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • New substituted 2,4-thiazolidinedione derivatives, processes for producing them and pharmaceutical compositions containing them
    Publication number: 20030100587
    Abstract: The present invention generally relates to a process for producing Compounds of formula I: 1
    Type: Application
    Filed: June 27, 2002
    Publication date: May 29, 2003
    Applicant: Merck Patent GmbH.
    Inventors: Gerard Moinet, Gerard Botton, Etienne Prugnard, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • (Aminoiminomethyl) amino) alkane-carboxamides and their applications in therapy
    Patent number: 6518458
    Abstract: The invention to a pharmaceutical composition comprising as active principle a compound of general formula (I), in which R1, R2, R3, and A are as defined in claim 1. These compositions can be used in the treatment of pathologies associated with insulin resistance syndrome.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: February 11, 2003
    Assignee: Merck Patent GmbH
    Inventors: Gérard Moinet, Daniel Cravo, Didier Mesangeau, Liliane Doare, Micheline Kergoat
  • Thiazolidone-2 derivatives, 4-diketone substituted, method for obtaining them and pharmaceutical compositions containing same
    Patent number: 6437143
    Abstract: The present invention relates to the field of chemistry and more particularly to that of therapeutic chemistry. The subject of the present invention is more precisely new 5-phenoxyalkyl-2,4-thiazolidinediones of general formula I: in which A represents a linear or branched alkylene group comprising from 2 to 16 carbon atoms D represents a homo- or heterocarbon mono-, di- or tricyclic aromatic structure which may include one or more heteroatoms X represents the substituent of the aromatic structure and is as defined in Claim 1 n is an integer ranging from 1 to 3 with the proviso that if A represents a butyl radical,  does not represent the 4-chlorophenyl group. The invention also relates to the tautomeric forms, to the enantiomers, diastereoisomers and epimers of the compounds of general formula I, in free or salified form.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: August 20, 2002
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Gérard Moinet, Gérard Botton, Etienne Prugnard, Liliane Doare, Micheline Kergoat, Didier Mesangeau
  • Antidiabetic piperazine derivatives, processes for their preparation and compositions containing them
    Patent number: 6376495
    Abstract: Piperazine derivatives of formula (I) wherein Z, X, n, Ar and i have the meanings defined herein are usefull in the treatment of pathologies associated with insulin-resistance syndrome.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: April 23, 2002
    Assignee: Merck Patent Gesellschaft
    Inventors: Gérard Moinet, Dominique Marais, Didier Mesangeau, Liliane Doare, Micheline Kergoat
  • 4-(1-piperazinyl) benzoic acid derivatives, process for preparing them and their therapeutic applications
    Patent number: 6281215
    Abstract: New 4-(1-piperazinyl)benzoic acid derivatives of the formula (I) are described. Also described is methods for making these compounds and their use as therapeutic agents. In particular, the compounds find use in the treatment of diabetes.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: August 28, 2001
    Assignee: Merck Patent GmbH
    Inventors: Gérard Moinet, Gérard Botton, Liliane Doare, Micheline Kergoat, Didier Messangeau