Patents by Inventor Gerhard Kohn
Gerhard Kohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20050129739Abstract: The production and use, and in particular, the extraction, separation, synthesis and recovery of polar lipid-rich fractions containing eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA(n-3) or DPA(n-6)), arachidonic acid (ARA), and eicosatetraneonoic acid (C20:4n-3) from microorganisms, genetically modified seeds and marine organisms (including fish and squid) and their use in human food applications, animal feed, pharmaceutical applications and cosmetic applications.Type: ApplicationFiled: May 14, 2002Publication date: June 16, 2005Inventors: Gerhard Kohn, Wulf Banzhaf, Jesus Abril
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Patent number: 6872570Abstract: A laboratory device for jointly tempering reaction samples in at least two steps in respectively assigned, specified temperature ranges, which are carried out repeatedly and consecutively as sequences of steps, the laboratory tempering device, in one step of the sequences of steps, bringing several groups of samples, in each case containing at least one sample, to temperatures within the temperature range, which are constant within the groups and different between the groups, wherein the laboratory tempering device, in each step of the sequence, brings a different partial amount of the samples in groups to temperatures, which are the same within the groups and different between the groups, and brings the samples of the other partial amounts to a same temperature within the assigned temperature range.Type: GrantFiled: December 11, 2001Date of Patent: March 29, 2005Assignee: Eppendorf AGInventor: Heinz Gerhard Köhn
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Publication number: 20030096396Abstract: A laboratory device for jointly tempering reaction samples in at least two steps in respectively assigned, specified temperature ranges, which are carried out repeatedly and consecutively as sequences of steps, the laboratory tempering device, in one step of the sequences of steps, bringing several groups of samples, in each case containing at least one sample, to temperatures within the temperature range, which are constant within the groups and different between the groups, wherein the laboratory tempering device, in each step of the sequence, brings a different partial amount of the samples in groups to temperatures, which are the same within the groups and different between the groups, and brings the samples of the other partial amounts to a same temperature within the assigned temperature range.Type: ApplicationFiled: December 11, 2001Publication date: May 22, 2003Inventor: Heinz Gerhard Kohn
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Publication number: 20020187249Abstract: A process for the production of surface-functionalized supports that serve as starting products for the production of microarrays for immobilizing biomolecules, in which process the surface of a support is coated with an initiator and the coated surface is then put in contact with a solution containing at least one first group of polymerizable monomers, whereby the monomers contain binding sites onto which the biomolecules (probe molecules) can bond, and whereby the conditions under which the monomers are put in contact with the activated support are selected in such a way that the monomers, mediated by the initiator, bind to the support and, on that basis, polymerize to form functional polymer chains in such a manner that a fixed structure consisting of adjacent functional polymer chains is formed on the surface of the support.Type: ApplicationFiled: February 1, 2002Publication date: December 12, 2002Inventors: Wilhelm Pluster, Mathias Ulbricht, Heinz Gerhard Kohn
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Patent number: 5895891Abstract: The invention relates to an electronic balance for use in an explosive environment. The invention calls for an intrinsically safe cable (1) which contains data lines in addition to the voltage supply lines. The data is serially transferred on the data lines.Type: GrantFiled: June 20, 1997Date of Patent: April 20, 1999Assignee: Sartorius AGInventors: Rainer Kirchhoff, Paul von der Haar, Heinz von Soosten, Christian Oldendorf, Heinz-Gerhard Kohn, Dieter Klausgrete
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Patent number: 5842965Abstract: A laboratory centrifuge is known with a centrifuge housing which contains a motor and a rotor connected with the motor through a drive shaft, the motor being held in the motor housing which includes an upper end shield and a lower end shield, and with the motor having a rotor tank arranged above it which has a passage for the drive shaft on the motor side. In order to indicate, starting from here, a laboratory centrifuge which is economical to manufacture and simple to assemble, which can be cooled easily, if necessary, it is proposed that the rotor tank and the upper end shield be made as a single piece.Type: GrantFiled: November 14, 1996Date of Patent: December 1, 1998Assignee: Heraeus Instruments GmbH & Co. KGInventors: Heinz-Gerhard Kohn, Rudiger Uhlendorf
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Patent number: 5771986Abstract: A toploaded balance in accordance with the principle of the electromagnetic compensation of force with a divided upper guide rod (3, 3') and a divided lower guide rod (4, 4') which together as a parallel guide connect a load receiver (2) to a system carrier (1) fixed to the housing, which system carrier (1), load receiver (2) and guide rods (3, 3', 4, 4') form a one-piece base, with a translation lever (5) rotatably mounted by two flexible articulations (7) on the system carrier (1), with a coupling element (12) connected by flexible articulations on the one hand to the load receiver (2) and on the other hand to the short lever arm of the translation lever (5), with a magnet build, as viewed from above, into the free space between the parts of the guide rods (3, 3', 4, 4') and their extensions on the system-carrier side and with a coil fastened on the longer lever arm of the translation lever (5) and extending into the air gap of the magnet, the translation lever (5), the two flexible articulations (7) for moType: GrantFiled: July 18, 1995Date of Patent: June 30, 1998Assignee: Sartorius AGInventors: Heinz-Gerhard Kohn, Jorg Peter Martens, Michael Laubstein, Carsten Tischer, Winfried Graf, Eduard Bierich
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Patent number: 5719357Abstract: A lop loaded balance with a load receiver (1, 2, 3) connected by at least one upper (11) and at least one lower guide rod in the form of a parallel guide to a system carrier (4) fixed to the housing, which load receiver, guide rods and system carrier are manufactured from one piece. The system carrier (4, 5, 6, 7) is designed as a frame. The frame-like system carrier is completely surrounded by a second frame (14, 15, 16, 17) supported on the balance feet and that both frames are constructed in a one-piece manner and are connected to one another in such a manner that twistings of the one frame are transferred as little as possible onto the other frame.Type: GrantFiled: July 18, 1995Date of Patent: February 17, 1998Assignee: Sartorius AGInventors: Matthias Eger, Heinz-Gerhard Kohn, Werner Schulze
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Patent number: 5686301Abstract: A cell culture vessel which permits gentle but vigorous intermixing and suspending of the cell culture during rotation. The culture vessel features a cell mixing and suspending device combined with a gas exchange membrane such that ample gas exchange occurs without the need to feed oxygen to the cells. The cell mixing and suspending device comprises a baffle system having at least one, and preferably more than one, mixing elements integral with the gas exchange membrane. Movement of the culture vessel, such as for example by rolling, shaking or swirling, moves the mixing elements such that the cells which are to be cultivated are gently intermixed and stably suspended within the cell culture chamber. Pressure variations within the cell culture vessel are accommodated by pressure equalizing device. The pressure equalizing device preferably comprises pressure sheathing made of gas permeable material positioned to form at least a portion of the outer wall of the supply chamber.Type: GrantFiled: September 2, 1994Date of Patent: November 11, 1997Assignee: Heraeus Instruments GmbHInventors: Frank W. Falkenberg, Hans-Otto Nagels, Heinz-Gerhard Kohn
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Patent number: 5610343Abstract: It is suggested for a balance with one or several weighing cells (1-4, 31) with a total of at least eight wire strain gauges (D.sub.1 -D.sub.4, S.sub.1 -S.sub.4), four of which (D.sub.1 -D.sub.4) are expanded under load and four (S.sub.1 -S.sub.4) compressed under load, in which the eight wire strain gauges are connected together circularly in series so as to form a single Wheatstone bridge which is supplied with voltage along a diagonal (12, 13) (vertical diagonal) and the output signal is taken off along the other diagonal (14, 15) (horizontal diagonal) that a signal is additionally tapped off along the upper horizontal chord (16, 17) and along the lower horizontal chord (18, 19). This makes possible a corner-load adjustment for the balance utilizing the additional signals.Type: GrantFiled: March 27, 1996Date of Patent: March 11, 1997Assignee: Sartorius AGInventors: Matthias Eger, Heinz-Gerhard Kohn, Werner Schulze, Christoph Berg
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Patent number: 5576211Abstract: Culture vessels for cell cultures having at least one cell culture chamber containing a cell culture mixture that is separated by a dialysis membrane from a nutrient medium in a nutrient supply chamber. Nutrients are transported through the dialysis membrane into the cell culture chamber and metabolic products are transported out of the cell culture chamber into the nutrient supply chamber. A gas exchange membrane that at least partly delimits the cell culture chamber and that is impermeable to liquids and to microorganisms that could contaminate the cell cultures is provided for feeding the gases required for cell culturing to the culture chamber and for discharging the gases generated during cell culturing. The cell culture chamber can advantageously be configured as a stand-alone module supporting both the dialysis membrane and the gas exchange membrane.Type: GrantFiled: April 18, 1995Date of Patent: November 19, 1996Assignee: Heraeus Instruments GmbHInventors: Frank W. Falkenberg, Hans-Otto Nagels, Heinz-Gerhard Kohn
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Patent number: 5539133Abstract: In the method of the invention to obtain lipids with a high proportion of long-chain polyunsaturated fatty acids (LCPs) with 20 to 22 carbon atoms by extraction from a raw material of animal or vegetable origin, unicellular algae (microalgae), macroalgae from the families of the brown, red and green algae and/or residues of alginate or carrageenin production with a water content of .ltoreq.50 weight % and a particle size of .ltoreq.50 mm are used. For extraction, an organic solvent or a compressed gas is used. A lipid extract with a high proportion of w6 LCP and w3 LCP and in particular with a content of at least 5 weight % of arachidonic acid and/or a content of at least 3 weight % of docosahexanoic acid is also prepared.Type: GrantFiled: February 28, 1994Date of Patent: July 23, 1996Assignee: Milupa AktiengesellschaftInventors: Gerhard Kohn, G unther Sawatzki, J urgen Erbe, Friedrich Schweikhardt
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Patent number: 5449617Abstract: Culture vessels for cell cultures having at least one cell culture chamber containing a cell culture mixture that is separated by a dialysis membrane from a nutrient medium in a nutrient supply chamber. Nutrients are transported through the dialysis membrane into the cell culture chamber and metabolic products are transported out of the cell culture chamber into the nutrient supply chamber. To provide a culture vessel for generating cell cultures with a high cell density that is economical to manufacture and easy to handle and to reduce the danger of infections, a gas exchange membrane, that at least partly delimits the cell culture chamber and that is impermeable to liquids and to microorganisms that could contaminate the cell cultures is provided for feeding the gases required for cell culturing to the culture chamber and for discharging the gases generated during cell culturing.Type: GrantFiled: September 2, 1993Date of Patent: September 12, 1995Assignee: Heraeus Sepatech GmbHInventors: Frank W. Falkenberg, Hans-Otto Nagels, Heinz-Gerhard Kohn
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Patent number: 5092994Abstract: To eliminate welds when forming connections from coupling joints of membrane filter structures having two external housing plates between which a membrane filter assembly (3, 4) is positioned, one (2) of the housing plates (1, 2) is formed with a bored or milled, essentially circular recess at each one of the locations where fluid connection couplings (6-9) are to be placed, the fluid connection couplings being formed by a plug element which is clamped in sealing engagement against a sealing bottom wall surface (13) of the respective recess. To provide absolute tightness, even of molecular substances such as bacteria, tissue elements, yeasts and the like, a sealing ring, preferably an O ring (15) is placed in a groove (14) formed in the sealing wall surface (13).Type: GrantFiled: May 2, 1991Date of Patent: March 3, 1992Assignee: Heraeus Sepatech GmbHInventors: Heinz-Gerhard Kohn, Eckart Kopowski, Helmut Kocher
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Patent number: 4952127Abstract: An improved method and apparatus for separating high-molecular-weight substances from cells suspended in liquid nutrient media, features continuous central monitoring and control of the process by a computer (22), and a way to combine the heretofore separate processes of first, separating media into solid and liquid components, and second, concentrating the proportion of high-molecular-weight components in the separated liquid. The media are conveyed by a first pump (3) to a centrifuge continuous flow rotor (2), which separates the solids from the liquid components and directs the latter to an intermediate reservoir (5), which sits on an electric scale (7) which is continuously monitored. From here they are fed to a filtration unit (9) in which the high-molecular-weight substances are separated and recycled through a feedback line (11), with the aid of a second pump (10), into the intermediate reservoir (5).Type: GrantFiled: September 6, 1989Date of Patent: August 28, 1990Assignee: Heraeus Sepatech GmbHInventors: Holger Schmeisser, Heinz-Gerhard Kohn
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Patent number: 4863603Abstract: A multilayer filter medium (6) is used for separating precipitates containing cholesterol from blood plasma which consists of at least one open filter medium (7) which adsorbs precipitate and of a microporous membrane (9) which controls the pressure conditions in the filter element, whereby the layer (7) which specifically adsorbs the precipitate is hydrophobic and the microporous membrane (9) is hydrophilic. In addition, a positively charged adsorption medium (9) is provided on the side of the microporous membrane (8) facing away from the hydrophobic adsorption medium (7). In this manner, a large adsorption area is created and kept accessible for the precipitates and for heparin.Type: GrantFiled: April 1, 1988Date of Patent: September 5, 1989Assignee: Sartorius GmbHInventors: Hans-Dieter Lehmann, Heinz-Gerhard Kohn
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Patent number: 4758337Abstract: In a filter for filtering human blood, especially in an extracorporeal circulatory system, with a blood inlet, a blood outlet and a vertically directed, hollow, cylindrical filter element located between them and consisting of a filter, and in which the hollow, cylindrical filter element seals housing chambers located in the filter housing between the blood inlet and the blood outlet in such a manner from each other by means of its front surfaces that the blood can only flow through the filter element, whereby the blood inlet is located in the center of the housing and of the hollow, cylindrical filter element and a gas outlet is located at the highest point of the housing, the blood inlet runs axially through the hollow cylinder of the filter element as a central ascending tube and divides it cross section into a smaller ascending pipe section and into a settling chamber section for the blood which is several times larger.Type: GrantFiled: November 7, 1986Date of Patent: July 19, 1988Assignee: Sartorius GmbHInventors: Heinz-Gerhard Kohn, Gunter Pradel
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Patent number: D370263Type: GrantFiled: October 12, 1994Date of Patent: May 28, 1996Assignee: Heraeus Instruments GmbHInventors: Frank W. Falkenberg, Hans-Otto Nagels, Heinz-Gerhard Kohn