Patents by Inventor Giovanni Rolando
Giovanni Rolando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9114010Abstract: A kit for facilitating crimping of a prosthetic heart valve for implantation at an aortic valve site in a human heart, the aortic valve site including a plurality of valve sinuses, the kit comprising a prosthetic aortic heart valve having a tubular structure and a first central axis including an anchoring structure comprising an annular outflow member, an annular inflow member, and a plurality of axial connection formations arranged in pairs angularly distributed around the central axis, and a plurality of leaflets coupled to the anchoring structure and adapted to substantially allow blood flow in a first direction and to substantially prevent blood flow in a second direction.Type: GrantFiled: March 22, 2013Date of Patent: August 25, 2015Assignee: Sorin Group Italia S.r.l.Inventors: Paolo Gaschino, Andrea Mariotto, Giovanni Rolando, Massimiliano Ares
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Publication number: 20140370599Abstract: A method of treating a biological tissue for biological prostheses includes steps of fixation of the biological tissue via a fixing solution including glutaraldehyde and detoxification of the fixed biological tissue via treatment with a detoxifying solution. The detoxification step includes one or both of eliminating phospholipids via treatment with an elimination solution and a treatment with a detoxifying solution. The elimination solution includes 1,2-octanediol and ethanol. The detoxifying solution includes taurine or homocysteic acid.Type: ApplicationFiled: July 28, 2014Publication date: December 18, 2014Inventors: Marina Strasly, Giovanni Rolando
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Patent number: 8822219Abstract: A method of treating a biological tissue for biological prostheses includes steps of fixation of the biological tissue via a fixing solution including glutaraldehyde and detoxification of the fixed biological tissue via treatment with a detoxifying solution. The detoxification step includes one or both of eliminating phospholipids via treatment with an elimination solution and a treatment with a detoxifying solution. The elimination solution includes 1,2-octanediol and ethanol. The detoxifying solution includes taurine or homocysteic acid.Type: GrantFiled: June 7, 2011Date of Patent: September 2, 2014Assignee: Sorin Group Italia S.r.l.Inventors: Marina Strasly, Giovanni Rolando
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Patent number: 8808367Abstract: A device for implanting an expandable heart valve prosthesis at a valve annulus in a patient's heart includes an implantation device configured to extend from a first opening in the patient's body, through the patient's aorta, through a valve annulus, through an opening in a ventricle, and to exit through the patient's thoracic region. The device further includes a port having a hemostasis valve for providing access through the patient's thoracic region and into the ventricle and at least two interchangeable modules configured for delivery using the implantation device.Type: GrantFiled: September 7, 2007Date of Patent: August 19, 2014Assignees: Sorin Group Italia S.r.l., Mayo Foundation for Medical Education and ResearchInventors: Rakesh Mark Suri, Franco Vallana, Giovanni Rolando, Giovanni Righini, Brent Russell Phillips, Eric Manasse
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Publication number: 20140207011Abstract: A device for measuring an internal dimension of a native cardiac valve annulus includes an elongated support member having a proximal portion and a distal portion. A measuring portion is coupled to the distal portion, and an indicator is coupled to the proximal portion of the support member. The measuring portion is biased towards a deployed configuration such that when deployed it applies an outwardly directed radial force to the native valve annulus.Type: ApplicationFiled: March 22, 2014Publication date: July 24, 2014Applicant: Sorin Group Italia S.r.l.Inventors: Giovanni Righini, Felice Giuseppe Carlino, Giovanni Rolando
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Publication number: 20140188217Abstract: A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.Type: ApplicationFiled: February 10, 2014Publication date: July 3, 2014Applicant: Sorin Group Italia S.r.I.Inventors: Giovanni Rolando, Paolo Gaschino, Monica Achiluzzi, Felice Giuseppe Carlino
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Patent number: 8715207Abstract: A device for measuring an internal dimension of a native cardiac valve annulus includes an elongated support member having a proximal portion and a distal portion. A measuring portion is coupled to the distal portion, and an indicator is coupled to the proximal portion of the support member. The measuring portion is biased towards a deployed configuration such that when deployed it applies an outwardly directed radial force to the native valve annulus.Type: GrantFiled: March 18, 2010Date of Patent: May 6, 2014Assignee: Sorin Group Italia S.r.l.Inventors: Giovanni Righini, Felice G. Carlino, Giovanni Rolando
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Patent number: 8685084Abstract: A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.Type: GrantFiled: December 28, 2012Date of Patent: April 1, 2014Assignee: Sorin Group Italia S.r.l.Inventors: Giovanni Rolando, Paolo Gaschino, Monica Achiluzzi, Felice Giuseppe Carlino
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Publication number: 20140052243Abstract: A device for anchoring a prosthetic heart valve on biological tissue, includes first and second anchoring assemblies, mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.Type: ApplicationFiled: February 10, 2012Publication date: February 20, 2014Applicant: SORIN GROUP ITALIA S.r.I.Inventors: Giovanni Rolando, Mauro Ercolani, Paolo Gaschino, Andrea Marchisio
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Publication number: 20140052244Abstract: A device for anchoring on biological tissue a prosthetic heart valve, includes first and second anchoring assemblies mutually couplable to secure biological tissue therebetween. The anchoring assemblies include at least one pair of complementary arched portions having anchoring formations for anchoring on the biological tissue. The anchoring formations include integral extensions of the anchoring assemblies extending radially outwardly of one of the anchoring assemblies.Type: ApplicationFiled: February 10, 2012Publication date: February 20, 2014Applicant: Sorin Group Italia S.r.lInventors: Giovanni Rolando, Mauro Ercolani, Paolo Gaschino, Andrea Marchisio
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Publication number: 20140046434Abstract: Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion.Type: ApplicationFiled: August 8, 2013Publication date: February 13, 2014Applicant: Sorin Group Italia S.r.l.Inventors: Giovanni Rolando, Paolo Gaschino, Laura Ghione, Andrea Marchisio, Monica Achiluzzi
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Publication number: 20130268068Abstract: A support device for implanting a stentless heart valve prosthesis having three leaflets adapted for coapting and defining three corresponding commissures is disclosed. The support device includes a shaft defining a manipulation axis, the shaft having a proximal portion and a distal portion, and three support formations integrally formed and extending from the proximal end of the shaft, the support formations angularly distributed about the manipulation axis of the shaft, such that each of the support formations correspond to locations of each of the commissures of the stentless heart valve prosthesis. The shaft includes a connection portion flexibly connecting the shaft and the support formations to permit a displacement of the manipulation axis with respect to the support formations. The shaft, the plurality of support formations and the connection portion are integrally formed from a single tubular element.Type: ApplicationFiled: March 15, 2013Publication date: October 10, 2013Applicant: Sorin Group Italia S.r.l.Inventors: Andrea Marchisio, Giovanni Rolando, Paolo Gaschino
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Publication number: 20130261742Abstract: A kit for facilitating crimping of a prosthetic heart valve for implantation at an aortic valve site in a human heart, the aortic valve site including a plurality of valve sinuses, the kit comprising a prosthetic aortic heart valve having a tubular structure and a first central axis including an anchoring structure comprising an annular outflow member, an annular inflow member, and a plurality of axial connection formations arranged in pairs angularly distributed around the central axis, and a plurality of leaflets coupled to the anchoring structure and adapted to substantially allow blood flow in a first direction and to substantially prevent blood flow in a second direction.Type: ApplicationFiled: March 22, 2013Publication date: October 3, 2013Applicant: Sorin Group Italia S.r.I.Inventors: Paolo Gaschino, Andrea Mariotto, Giovanni Rolando, Massimiliano Ares
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Publication number: 20130253643Abstract: A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.Type: ApplicationFiled: March 15, 2013Publication date: September 26, 2013Applicant: Sorin Group Italia S.r.l.Inventors: Giovanni Rolando, Paolo Gaschino, Antonella Orecchia, Monica Achiluzzi, Massimiliano Ares
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Patent number: 8512397Abstract: A prosthetic vascular conduit for coupling to a valve having an annular portion includes a terminal collar member, radially expandable to receive the annular portion of the valve. The collar member includes a portion which is radially contractible to capture the annular portion of the valve to couple the valve to the conduit.Type: GrantFiled: April 27, 2009Date of Patent: August 20, 2013Assignee: Sorin Group Italia S.r.l.Inventors: Giovanni Rolando, Paolo Gaschino, Monica F. Achiluzzi, Felice G. Carlino
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Patent number: 8486137Abstract: A system for implanting a heart valve prosthesis in a patient's heart includes a balloon expandable, tissue, stented heart valve, and an apical valve delivery device for delivering the stented heart valve to a target site in the patient's heart. The delivery device includes an inflation balloon module for expanding the stented heart valve prosthesis, markers on the delivery device to assist in location of the delivery device at an appropriate location, and a streamlined cap.Type: GrantFiled: June 27, 2008Date of Patent: July 16, 2013Assignees: Sorin Group Italia S.r.l., Mayo Foundation for Medical Education and ResearchInventors: Rakesh M. Suri, Franco Vallana, Giovanni Rolando, Giovanni Righini, Brent R. Phillips, Eric Manasse
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Patent number: 8475521Abstract: A system for implanting a heart valve prosthesis in a patient's heart includes a balloon expandable, tissue, stented heart valve and a transfemoral valve delivery device for delivering the stented heart valve to a target site in the patient's heart. The delivery device includes an inflation balloon module for expanding the stented heart valve prosthesis, markers on to assist in location of the delivery device at an appropriate location; and a streamlined cap.Type: GrantFiled: June 27, 2008Date of Patent: July 2, 2013Assignees: Sorin Group Italia S.r.l., Mayo Foundation for Medical Education and ResearchInventors: Rakesh M. Suri, Franco Vallana, Giovanni Rolando, Giovanni Righini, Brent R. Phillips, Eric Manasse
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Patent number: 8470024Abstract: An instrument for positioning a cardiac valve prosthesis in a vessel includes a wire element to slidingly guide the valve prosthesis towards an implantation site and an expandable element coupled to the wire element. The expandable element is expandable in the vessel to position the wire element in association with the implantation site. A method for positioning a cardiac valve prosthesis includes securing a delivery instrument at an appropriate location at the implantation site and delivering the valve prosthesis to the implantation site using the delivery instrument.Type: GrantFiled: December 19, 2006Date of Patent: June 25, 2013Assignee: Sorin Group Italia S.r.l.Inventors: Laura Ghione, Giovanni Righini, Eric Manasse, Giovanni Rolando, Paolo Gaschino, Dong Ik Shin
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Patent number: 8439965Abstract: An angioplasty stent comprises a body comprising a plurality of successive segments connected in pairs by bridge means so that the successive segments can be oriented relative to one another for the purposes of bending of the body in any direction defined by a linear combination of respective orientation axes defined by the bridge connection means. During the radial expansion of the stent, the axial contraction of the segments resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements from the respective concave portions. The wall of the body comprises arms for supporting a lumen as well as regions which are selectively deformable during the expansion of the stent, the arms and the selectively deformable regions having different cross-sections and/or cross-sectional areas. At least one portion of the body may have a substantially reticular structure, the branches of which define geometrical figures identifiable as fractals.Type: GrantFiled: May 5, 2011Date of Patent: May 14, 2013Assignee: CID S.p.A.Inventors: Giovanni Rolando, Paolo Gaschino, Franco Vallana, Osvaldo Cerise
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Publication number: 20120323312Abstract: The present invention provides a stent for implantation at a site within a human or animal body comprising: an expandable body having an inner surface and an outer surface; and treatment agents applied to the outer surface of the expandable body, the treatment agents comprising a combination of Paclitaxel and FK506 or their derivatives or analogues.Type: ApplicationFiled: August 28, 2012Publication date: December 20, 2012Applicant: SORIN BIOMEDICA CARDIO S.R.L.Inventors: Maria Curcio, Enrico Pasquino, Giovanni Rolando, Andrea Grignani