Abstract: The present invention provides methods for sequencing and analysis of nucleic acids and determining that a subject is positive for a non-usual interstitial pneumonia subtype.

Abstract: Provided herein are methods and systems for analyzing a sample of a subject to determine whether the subject has, or is at risk of having or developing, a cancer, such as lung cancer.

Abstract: The present invention provides methods for sequencing and analysis of nucleic acids and determining that a subject is positive for a non-usual interstitial pneumonia subtype.

Abstract: Gene fusions are hybrid genes formed by two previously separate genes. Many such gene fusions may be strong driver mutations for cancer and may play important roles in tumorigenesis. Gene fusions may be identified in biological samples extracted from the diseased location. However, for lung cancer, extracting samples from the nodules may be challenging and may lead to undesirable consequences. Disclosed herein is a method and system of identifying a gene fusion landscape from bronchial brushings and further identifying fusions that may be potentially associated with lung cancer.

Abstract: The present disclosure provides systems and methods for sequencing and analysis of nucleic acids.

Abstract: Provided herein are methods and systems for analyzing a sample of a subject by using a trained algorithm to evaluate and classify the sample as indicating a risk of having or developing cancer.

Abstract: The methods disclosed herein can be used to determine sample integrity, such as sample identity, by using kinship coefficients. Kinship coefficients between two samples can be determined by measuring genetic relatedness in order to determine whether the samples are related or not related.

Abstract: The present disclosure provides systems and methods for sequencing and analysis of nucleic acids.

Abstract: The present disclosure provides methods for sequencing and analysis of nucleic acids.

Abstract: The present invention provides methods for sequencing and analysis of nucleic acids.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to genomic DNA markers associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: The present invention provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UTP) or non-UIP.

Abstract: The present disclosure provides methods for diagnosis of interstitial lung diseases (ILDs). The present disclosure provides methods for differential diagnosis of idiopathic pulmonary fibrosis from other ILDs. Compositions and kits useful in carrying out a subject method are also provided.

Abstract: Provided herein are methods, systems, and kits for improving the current clinical pathway of care for lung conditions using genomic classifiers at various decision points within the existing pathway to minimize unnecessary invasive procedures, enhance early detection and disease recurrence, and monitor efficacy of interventive therapies for prevention or disease reversal.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: Provided herein are methods and systems for analyzing a sample of a subject by using a trained algorithm to classify the samples as benign, suspicious for malignancy, or malignant. Further disclosed herein are methods and systems for identifying genetic aberrations to indicate risk of malignancy.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.