Patents by Inventor Goran Stemme
Goran Stemme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240082857Abstract: A method for forming a monolithic swirl nozzle configured to aerosolize a pharmaceutical drug. The swirl nozzle comprises an inlet for receiving the pharmaceutical drug to be aerosolized; a swirl chamber connected to the inlet and configured to aerosolize the pharmaceutical drug provided by the inlet; and an outlet connected to the swirl chamber and configured to discharge the aerosolized pharmaceutical drug. The method comprises providing a photoactivatable material and forming the swirl nozzle by selectively activating voxels in the photoactivatable material.Type: ApplicationFiled: January 18, 2022Publication date: March 14, 2024Inventors: Torben Last, Niclas Roxhed, Göran Stemme
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Publication number: 20240023850Abstract: A microneedle (100) for extracting a blood sample from the skin (10) of a mammal subject is disclosed. The microneedle comprises at least one substantially flat blade (110) comprising at least one cutting edge (120a, 120b) configured to incise the skin of the mammal subject, and at least one microchannel (130) comprising an opening (132) and a passage (134). The at least one microchannel is arranged adjacent to the at least one blade and configured to be inserted into the skin of the mammal subject together with the at least one blade. The passage is configured to transport the blood sample away from the opening via capillary action. A device (200) for extracting a blood sample from a mammal subject comprising a microneedle is also disclosed.Type: ApplicationFiled: October 14, 2021Publication date: January 25, 2024Inventors: Niclas Roxhed, Mikolaj Dobielewski, Göran Stemme
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Publication number: 20230279324Abstract: The method is for preparing a sample in a microfluidic device. A microfluidic device is provided that has a first reservoir in fluid communication with a second reservoir in fluid communication with and adjacent to a draining unit that has a first absorbing member disposed therein. The first reservoir contains a first liquid that is held in the first reservoir by a capillary stop valve connecting the first and second reservoirs. The second reservoir has a sample support disposed therein. A second liquid, containing substances, is added to the second reservoir. The second liquid contacts the first liquid and the first absorbing member. The first absorbing member absorbs the second liquid and the first liquid. The substances adhere to the sample support.Type: ApplicationFiled: September 9, 2022Publication date: September 7, 2023Inventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
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Patent number: 11504959Abstract: A method for transferring an atomically thin layer comprising providing a target substrate and a donor substrate on which a first atomically thin layer has been formed. The method further comprises disposing an adhesion layer at the donor substrate or at the target substrate. The method further comprises bringing the target substrate and the donor substrate together. Further, the method comprises bonding together the donor substrate, the adhesion layer and the target substrate and removing the donor substrate.Type: GrantFiled: January 24, 2020Date of Patent: November 22, 2022Inventors: Arne Quellmalz, Kristinn Gylfason, Niclas Roxhed, Göran Stemme, Frank Niklaus
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Patent number: 11485945Abstract: The method is for preparing a sample in a microfluidic device. A microfluidic device is provided that has a first reservoir in fluid communication with a second reservoir in fluid communication with and adjacent to a draining unit that has a first absorbing member disposed therein. The first reservoir contains a first liquid that is held in the first reservoir by a capillary stop valve connecting the first and second reservoirs. The second reservoir has a sample support disposed therein. A second liquid, containing substances, is added to the second reservoir. The second liquid contacts the first liquid and the first absorbing member. The first absorbing member absorbs the second liquid and the first liquid. The substances adhere to the sample support.Type: GrantFiled: September 18, 2020Date of Patent: November 1, 2022Assignee: Intelligent Virus Imaging IncInventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
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Patent number: 11484882Abstract: The microfluidic device has a first reservoir that preferably includes a first liquid. The first liquid is being held by a capillary stop valve in the first reservoir. A second reservoir is in fluid communication with the first reservoir. The second reservoir has a second liquid and a sample support disposed therein. The second reservoir has an inlet opening defined therein. A draining unit is adjacent to the second reservoir. The draining unit is in fluid communication with the second reservoir. The draining unit has a first absorption member disposed therein.Type: GrantFiled: September 17, 2020Date of Patent: November 1, 2022Assignee: Intelligent Virus Imaging Inc.Inventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
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Patent number: 11442026Abstract: Disclosed is a method of making a crack structure on a substrate, the crack structure being usable as a tunnelling junction structure in a nanogap device, including the controlled fracture or release of a patterned layer under built-in stress, thereby forming elements separated by nanogaps or crack-junctions. The width of the crack-defined nanogap is controlled by locally release-etching the film at a notched bridge patterned in the film. The built-in stress contributes to forming the crack and defining of the width of the crack-defined nanogap. Further, by design of the length of the bridge in a range between sub-??? to >25???, the separation between the elements, defined by the width of the crack-defined nanogaps, can be controlled for each individual crack structure from <2 nm to >100 nm. The nanogaps can be used for tunneling devices in combination with nanopores for DNA, RNA or peptides sequencing.Type: GrantFiled: August 19, 2020Date of Patent: September 13, 2022Assignee: Zedna ABInventors: Valentin Dubois, Frank Niklaus, Göran Stemme
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Publication number: 20220250961Abstract: The present invention relates to a method for forming a 3D optical component comprising the steps of: forming over a substrate a liquid layer of a polymer in a solvent, drying said polymer for removing at least a portion of said solvent and thereby creating a layer having a first dissolution rate, exposing by multi-photon absorption using an electromagnetic radiation source a predefined volume of said layer, thereby causing the volume to have a second dissolution rate which is different to said first dissolution rate, dissolve the non-exposed areas with a liquid solution for forming the 3D optical component, wherein said polymer is Hydrogen silsesquioxane, HSQ, and said dried layer having a thickness of at least 1 ?m.Type: ApplicationFiled: February 9, 2021Publication date: August 11, 2022Inventors: Po-Han Huang, Göran Stemme, Frank Niklaus, Kristinn B. Gylfason, Miku Laakso, Pierre Edinger, Carlos Errando Herranz, David Emmanuel Marschner, Lee-Lun Lai
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Publication number: 20220081662Abstract: The method is for preparing a sample in a microfluidic device. A microfluidic device is provided that has a first reservoir in fluid communication with a second reservoir in fluid communication with and adjacent to a draining unit that has a first absorbing member disposed therein. The first reservoir contains a first liquid that is held in the first reservoir by a capillary stop valve connecting the first and second reservoirs. The second reservoir has a sample support disposed therein. A second liquid, containing substances, is added to the second reservoir. The second liquid contacts the first liquid and the first absorbing member. The first absorbing member absorbs the second liquid and the first liquid. The substances adhere to the sample support.Type: ApplicationFiled: September 18, 2020Publication date: March 17, 2022Inventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
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Publication number: 20220080419Abstract: The microfluidic device has a first reservoir that preferably includes a first liquid. The first liquid is being held by a capillary stop valve in the first reservoir. A second reservoir is in fluid communication with the first reservoir. The second reservoir has a second liquid and a sample support disposed therein. The second reservoir has an inlet opening defined therein. A draining unit is adjacent to the second reservoir. The draining unit is in fluid communication with the second reservoir. The draining unit has a first absorption member disposed therein.Type: ApplicationFiled: September 17, 2020Publication date: March 17, 2022Inventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
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Publication number: 20220072241Abstract: A spray nozzle chip comprising: a first layer provided with a first layer orifice, and a mechanically flexible nozzle layer provided with a nozzle orifice, wherein the first layer has a valve seat arranged aligned with the nozzle orifice, wherein the spray nozzle chip has a valve functionality obtained by movement of the nozzle layer relative to the valve seat due to pressure changes, and wherein the nozzle layer is arranged at a distance from the valve seat when the nozzle layer is in a default non-pressurised state, whereby a gap with a gap length (L) is formed between the nozzle layer and the valve seat, wherein the gap length (L) is smaller than a dimension of a specific bacterial type, to thereby seal against bacterial ingrowth through the nozzle orifice of the specific bacterial type.Type: ApplicationFiled: December 27, 2019Publication date: March 10, 2022Inventors: Niclas Roxhed, Torben Last, Göran Stemme
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Patent number: 11254488Abstract: A spray nozzle chip is presented having: a first layer provided with a first layer orifice, a mechanically flexible nozzle layer provided with a nozzle orifice, the spray nozzle chip having a valve functionality obtained by movement of the nozzle layer relative to the first layer due to pressure changes, wherein the nozzle orifice is closed when the nozzle layer is in a default non-pressurised state and wherein the nozzle orifice is opened and set in fluid communication with the first layer orifice when the nozzle layer is deformed due to pressure during a spraying operation, and wherein the spray nozzle chip further has a sealing layer configured to rupture when the nozzle layer is deformed due to applied pressure during a spraying operation.Type: GrantFiled: December 5, 2018Date of Patent: February 22, 2022Assignee: SHL MEDICAL AGInventors: Niclas Roxhead, Torben Last, Göran Stemme
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Patent number: 11000846Abstract: A capillary driven microfluidic device with blood plasma separation means that can be used to separate, meter and transfer a blood sample. The blood separation means can be arranged as a capillary pump by the configuration of a porous membrane and the microfluidic device.Type: GrantFiled: December 20, 2017Date of Patent: May 11, 2021Assignee: CAPITAINER ABInventors: Niclas Roxhed, Göran Stemme, Gabriel Lenk, Wouter Van Der Wijngaart, Jonas Hansson
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Publication number: 20200385201Abstract: A spray nozzle chip is presented having: a first layer provided with a first layer orifice, a mechanically flexible nozzle layer provided with a nozzle orifice, the spray nozzle chip having a valve functionality obtained by movement of the nozzle layer relative to the first layer due to pressure changes, wherein the nozzle orifice is closed when the nozzle layer is in a default non-pressurised state and wherein the nozzle orifice is opened and set in fluid communication with the first layer orifice when the nozzle layer is deformed due to pressure during a spraying operation, and wherein the spray nozzle chip further has a sealing layer configured to rupture when the nozzle layer is deformed due to applied pressure during a spraying operation.Type: ApplicationFiled: December 5, 2018Publication date: December 10, 2020Inventors: Niclas Roxhead, Torben Last, Göran Stemme
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Patent number: 10782249Abstract: Disclosed is a method of making a crack structure on a substrate, the crack structure being usable as a tunneling junction structure in a nanogap device, including the controlled fracture or release of a patterned layer under built-in stress, thereby forming elements separated by nanogaps or crack-junctions. The width of the crack-defined nanogap is controlled by locally release-etching the film at a notched bridge patterned in the film. The built-in stress contributes to forming the crack and defining of the width of the crack-defined nanogap. Further, by design of the length of the bridge in a range between sub-??? to >25???, the separation between the elements, defined by the width of the crack-defined nanogaps, can be controlled for each individual crack structure from <2 nm to >100 nm. The nanogaps can be used for tunneling devices in combination with nanopores for DNA, RNA or peptides sequencing.Type: GrantFiled: December 14, 2016Date of Patent: September 22, 2020Assignee: ZEDNA ABInventors: Valentin Dubois, Frank Niklaus, Göran Stemme
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Patent number: 10598590Abstract: A sensor device comprising a planar substrate defining a substrate plane and a waveguide for guiding an electromagnetic wave. The waveguide extends in a length direction in a waveguide plane parallel to the substrate plane and has a width and a height wherein the width to height ratio is more than 5. The height of the waveguide is less than the wavelength of the electromagnetic wave. The waveguide is supported on the substrate by a support structure extending from the substrate to the waveguide, along the length direction of the waveguide, having a width which is smaller than the width of the waveguide. The invention further relates to a method of detecting a component in gas and a method of fabricating a sensor device.Type: GrantFiled: January 8, 2019Date of Patent: March 24, 2020Assignee: Senseair ABInventors: Kristinn B. Gylfason, Hans Sohlström, Floria Ottonello Briano, Göran Stemme
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Patent number: 10525239Abstract: The disclosure relates to a cerebrospinal fluid (CSF) shunt for treatment of hydrocephalus, comprising a valve having an inlet port and an outlet port, which ports are for draining CSF, and a control port for regulating the drainage of CSF through the valve according to a hydrostatic pressure provided to the control port, which hydrostatic pressure is dependent on the body position of the patient. The disclosure further relates to a method for treatment of hydrocephalus comprising regulating drainage of CSF based on a hydrostatic pressure that is dependent on the body position of the patient.Type: GrantFiled: March 31, 2015Date of Patent: January 7, 2020Inventors: Niclas Roxhed, Staffan Johansson, Göran Stemme, Anders Eklund, Jan Malm
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Patent number: 10433766Abstract: The invention relates to a miniaturised fluid flow regulating device comprising a fluid flow channel with an inlet portion, an outlet portion and a flow regulation passage between the inlet portion and the outlet portion, an elongated beam element arranged in the flow channel, such that a pressure difference over the inlet portion and the outlet portion causes the beam element to bend and regulate fluid flow in the flow regulation passage. The invention further relates to a breath analysis device comprising such a flow regulating device for regulating a flow of exhaled breath.Type: GrantFiled: January 23, 2015Date of Patent: October 8, 2019Assignee: CIRCASSIA ABInventors: Niclas Roxhed, Göran Stemme, Staffan Johansson
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Publication number: 20190154570Abstract: A sensor device comprising a planar substrate defining a substrate plane and a waveguide for guiding an electromagnetic wave. The waveguide extends in a length direction in a waveguide plane parallel to the substrate plane and has a width and a height wherein the width to height ratio is more than 5. The height of the waveguide is less than the wavelength of the electromagnetic wave. The waveguide is supported on the substrate by a support structure extending from the substrate to the waveguide, along the length direction of the waveguide, having a width which is smaller than the width of the waveguide. The invention further relates to a method of detecting a component in gas and a method of fabricating a sensor device.Type: ApplicationFiled: January 8, 2019Publication date: May 23, 2019Inventors: Kristinn B. Gylfason, Hans Sohlström, Floria Ottonello Briano, Göran Stemme
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Patent number: 10220389Abstract: A microfluidic device comprises an inlet port for liquid, and a capillary channel in fluid connection to the inlet port for receiving liquid from the inlet port, the channel having a defined volume. At least one dissolvable valve is provided comprising a dissolvable membrane having a first side oriented towards the capillary channel, and a capillary connected to the second side of the dissolvable membrane such that when the membrane is dissolved by the liquid, liquid is transported through the valve to the second side of the membrane by capillary action. A method of controlling a flow of liquid uses such a microfluidic device.Type: GrantFiled: September 30, 2014Date of Patent: March 5, 2019Assignee: CAPITAINER ABInventors: Göran Stemme, Gabriel Lenk, Olof Beck, Niclas Roxhed