Patents by Inventor Gordon M. Keller

Gordon M. Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cardiomyocyte Cell Populations
    Publication number: 20100158872
    Abstract: The present invention provides methods for inducing the differentiation of cardiac progenitor cells and cell populations produced by the methods of the invention. The invention further provides a method of screening for agents that affect cardiomyocytes, and a method of cardiomyocyte replacement therapy.
    Type: Application
    Filed: June 22, 2006
    Publication date: June 24, 2010
    Applicant: Mount Sinai School of Medicine of New York Univers
    Inventors: Gordon M. Keller, Chang-Yi Chen
  • Mesoderm and definitive endoderm cell populations
    Publication number: 20080226558
    Abstract: The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
    Type: Application
    Filed: March 24, 2008
    Publication date: September 18, 2008
    Applicant: Mount Sinai School of Medicine of New York University
    Inventors: Gordon M. Keller, Valerie Kouskoff, Atsushi Kubo, Hans Joerg Fehling
  • Cell populations and methods of production thereof
    Patent number: 7374934
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: May 20, 2008
    Assignee: National Jewish Medical and Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Method for identification of cell growth or differentiation factors
    Publication number: 20040106195
    Abstract: The present invention relates to novel immortalized precurso cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Application
    Filed: April 28, 2003
    Publication date: June 3, 2004
    Applicant: Jewish Medical and Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Method for production of neutrophils and uses therefor
    Publication number: 20040076617
    Abstract: An in vitro method for the differentiation of functionally mature neutrophils from stem cells is disclosed. Also disclosed are methods of producing genetically modified neutrophils in vitro and methods of using the neutrophils produced according to the invention.
    Type: Application
    Filed: March 18, 2003
    Publication date: April 22, 2004
    Inventors: Jonathan Gregory Lieber, George Scott Worthen, Saiphone Webb, Gordon M. Keller
  • Novel embryonic cell populations and methods to isolate such populations
    Publication number: 20030175955
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Application
    Filed: August 13, 2002
    Publication date: September 18, 2003
    Applicant: National Jewish Medical and Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Method for identification of cell growth or differentiation factors
    Patent number: 6576433
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: June 10, 2003
    Assignee: National Jewish Medical & Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Method for identification of cell growth or differentiation factors
    Patent number: 6555318
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: April 29, 2003
    Assignee: National Jewish Medical and Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Method for identification of cell growth or differentiation factors
    Publication number: 20020187548
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Application
    Filed: January 22, 2001
    Publication date: December 12, 2002
    Applicant: National Jewish Medical and Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Method to produce novel embryonic cell populations
    Patent number: 6110739
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: August 29, 2000
    Assignee: National Jewish Medical and Research Center
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi
  • Embryonic cell populations and methods to isolate such populations
    Patent number: 5914268
    Abstract: The present invention relates to novel pluripotent embryonic cell populations derived from embryonic stem cell populations and methods to produce such pluripotent embryonic cell populations. Disclosed is an embryonic stem cell-derived pluripotent embryoid body cell population having one or more cells capable of developing into cells of hematopoietic and/or endothelial lineage. Also disclosed is an embryoid body cell population-derived mixed population of endothelial and erythroid cells. Also disclosed is an embryoid body cell population-derived embryonic blast cell population capable of developing into a variety of hematopoietic cell types. The invention is additionally directed to embryonic stem cell population-derived T and B cell populations. Methods to identify embryonic cell compounds are also disclosed for therapeutic and experimental use.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: June 22, 1999
    Assignee: National Jewish Center for Immunology & Respiratory Medicine
    Inventors: Gordon M. Keller, Marion Kennedy, Kyunghee Choi, Meri T. Firpo
  • Embryonic cell populations and methods to isolate such populations
    Patent number: 5874301
    Abstract: The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay to identify regulatory compounds capable of controlling cell growth for therapeutic and experimental use.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: February 23, 1999
    Assignee: National Jewish Center for Immunology and Respiratory Medicine
    Inventors: Gordon M. Keller, Robert G. Hawley, Kyunghee Choi