Patents by Inventor Grace Chen

Grace Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250120995
    Abstract: Characterization of drug-drug interaction properties and pharmacological properties of maribavir is useful to inform potential drug-drug interactions and dosing strategies when administering with co-medications.
    Type: Application
    Filed: December 20, 2024
    Publication date: April 17, 2025
    Inventors: Heng SONG, Kefeng SUN, Matthew CROUTHAMEL, Grace CHEN, Andy Z. X. ZHU, Ingrid Nicolle MICHON, Howard James BURT, Zoe Elizabeth BARTER, Sibylle NEUHOFF
  • Publication number: 20250056388
    Abstract: A user equipment (UE) having multiple Subscriber Identity Modules (SIMs) scans for network connections using each of the multiple SIMs in sequence, until either a network connection is found, or the UE determines that there is no available network connection. Each of the multiple SIMs supports connection to a different network. In response to a primary SIM of the UE identifying an out-of-service (OOS) condition for the corresponding network, the UE sequentially employs a different one of the multiple SIMs to attempt to connect to a different network. This increases the likelihood that the UE is able to connect to a network, thereby improving the overall user experience.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Inventors: Edison Chen, Grace I. Chen
  • Patent number: 12213989
    Abstract: Characterization of drug-drug interaction properties and pharmacological properties of maribavir is useful to inform potential drug-drug interactions and dosing strategies when administering with co-medications.
    Type: Grant
    Filed: April 25, 2024
    Date of Patent: February 4, 2025
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Heng Song, Kefeng Sun, Matthew Crouthamel, Grace Chen, Andy Z. X. Zhu, Ingrid Nicolle Michon, Howard James Burt, Zoe Elizabeth Barter, Sibylle Neuhoff
  • Patent number: 12140550
    Abstract: A photoluminescent material can be applied to part of a substrate as part of substrate inspection. The photoluminescent material includes a conjugated polymer having a coiled macroscopic molecular shape and a meta-linkage or an ortho-linkage. The substrate is imaged using an inspection system. The conjugated polymer can be, for example, poly(m-phenylene ethynylene) (PPE) or poly(para-phenylene vinylene) (PPV).
    Type: Grant
    Filed: January 25, 2023
    Date of Patent: November 12, 2024
    Assignee: KLA Corporation
    Inventors: Jinsang Kim, Grace Chen
  • Publication number: 20240285663
    Abstract: Characterization of drug-drug interaction properties and pharmacological properties of maribavir is useful to inform potential drug-drug interactions and dosing strategies when administering with co-medications.
    Type: Application
    Filed: April 25, 2024
    Publication date: August 29, 2024
    Inventors: Heng SONG, Kefeng SUN, Matthew CROUTHAMEL, Grace CHEN, Andy Z. X. ZHU, Ingrid Nicolle MICHON, Howard James BURT, Zoe Elizabeth BARTER, Sibylle NEUHOFF
  • Publication number: 20240200118
    Abstract: The present disclosure details various compositions and/or methods of optimizing delivery systems the localized delivery of nucleic acid sequences, polypeptides or peptides for use in therapeutics and/or diagnostics.
    Type: Application
    Filed: February 16, 2024
    Publication date: June 20, 2024
    Inventors: Inna SHCHERBAKOVA, Grace CHEN, Abril Fleitas BEITANS, Brian GOODMAN, Ciaran LAWLOR, Kevin Yingxin YANG
  • Publication number: 20240156849
    Abstract: Characterization of drug-drug interaction properties and pharmacological properties of maribavir is useful to inform potential drug-drug interactions and dosing strategies when administering with co-medications.
    Type: Application
    Filed: December 29, 2023
    Publication date: May 16, 2024
    Applicants: Takeda Pharmaceuticals U.S.A., Inc, Certara USA, Inc.
    Inventors: Heng Song, Kefeng Sun, Matthew Crouthamel, Grace Chen, Andy Z.X. Zhu, Ingrid Nicolle Michon, Howard James Burt, Zoe Elizabeth Barter, Sibylle Neuhoff
  • Publication number: 20230383300
    Abstract: Compositions and methods of modulating an innate immune response with circular RNAs are disclosed. In particular, the disclosure relates to methods for modifying an RNA by circularization and the use of circular RNAs generated with exogenous introns to stimulate an innate immune response or circular RNAs generated with endogenous introns to prevent immune recognition of foreign RNA.
    Type: Application
    Filed: February 28, 2023
    Publication date: November 30, 2023
    Inventors: Howard Y. Chang, Ye Grace Chen, Bali Pulendran, Sudhir Kasturi
  • Patent number: 11814627
    Abstract: Compositions and methods of modulating an innate immune response with circular RNAs are disclosed. In particular, the disclosure relates to methods for modifying an RNA by circularization and the use of circular RNAs generated with exogenous introns to stimulate an innate immune response or circular RNAs generated with endogenous introns to prevent immune recognition of foreign RNA.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: November 14, 2023
    Assignees: THE BOARD OF THE LELAND STANFORD JUNIOR UNIVERSITY, EMORY UNIVERSITY
    Inventors: Howard Y. Chang, Ye Grace Chen, Bali Pulendran, Sudhir Kasturi
  • Patent number: 11715622
    Abstract: A material recovery system for an optical component includes a reservoir containing gas and configured to supply a gas flow containing the gas. The material recovery system also includes an ion beam generator disposed on the reservoir and configured to receive the gas flow and to ionize the gas in the gas flow to generate an ion beam. The ion beam is configured to be directed to the optical component to remove at least a portion of a F-containing optical material degraded by exposure to VUV radiation, DUV radiation, and/or photo-contamination.
    Type: Grant
    Filed: August 4, 2021
    Date of Patent: August 1, 2023
    Assignee: KLA CORPORATION
    Inventors: Gildardo Delgado, Vera (Guorong) Zhuang, John Savee, Evgeniia Butaeva, Gary V. Lopez Lopez, Grace Chen
  • Publication number: 20230236134
    Abstract: A photoluminescent material can be applied to part of a substrate as part of substrate inspection. The photoluminescent material includes a conjugated polymer having a coiled macroscopic molecular shape and a meta-linkage or an ortho-linkage. The substrate is imaged using an inspection system. The conjugated polymer can be, for example, poly(m-phenylene ethynylene) (PPE) or poly(para-phenylene vinylene) (PPV).
    Type: Application
    Filed: January 25, 2023
    Publication date: July 27, 2023
    Inventors: Jinsang Kim, Grace Chen
  • Publication number: 20220334040
    Abstract: Embodiments of the present invention provide an apparatus and method for determining whether a dosage unit of a pharmaceutical dmg disintegrates in an immersion fluid of a disintegration tester within a prescribed time limit and to record and transmit to human-accessible output devices the times required. In one implementation, the apparatus comprises a computer system, a motion sensor, a capture device, a fastener for attaching the capture device and motion sensor to the reciprocating arm of the disintegration tester, and one or more data communications interfaces to carry commands and data between the computer system, the motion sensor and the capture device.
    Type: Application
    Filed: September 29, 2020
    Publication date: October 20, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Grace Chen, Joanna C. Everitt, Sydney Floryanzia, Janakiraman Gopinath, Prashant I. Shah
  • Patent number: 11475431
    Abstract: Techniques associated with a customer-facing device and a merchant-facing device are described herein. In an example, a system can include a customer-facing device configured with a customer application that is executable on an operating system of the customer-facing device to (i) display information to a customer and (ii) receive input from the customer, wherein the customer-facing device includes a payment reader to read payment data from a payment instrument in association with a payment transaction between the customer and a merchant, and a merchant-facing device configured with a merchant application that is executable on an operating system of the merchant-facing device to (i) display information to the merchant and (ii) receive input from the merchant. In at least one example, the customer-facing device and the merchant-facing device can communicate to process, at least in part, the payment transaction associated with the payment instrument via a remote payment service system.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: October 18, 2022
    Assignee: Block, Inc.
    Inventors: Edward Ruder, James Puls, Mehdi Mulani, Shawn Morel, Grace Chen, Christopher R. Clark, J. Bryan Scott, Eric Monti
  • Patent number: 11283839
    Abstract: Predicting access impact of a plurality of rule changes on a corpus of information assets is provided. A set of affected rules in a new rule space for controlling access to the corpus of information assets is received. The set of affected rules is shredded to identify right-hand side terms contained in predication blocks of the set of affected rules. An enforcement knowledge graph is traversed to identify a set of hot information assets having same terms as the right-hand side terms of the set of affected rules. The set of hot information assets having the same terms as the right-hand side terms of the set of affected rules is added to a hash table of hot information assets.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: March 22, 2022
    Assignee: International Business Machines Corporation
    Inventors: Roger C. Raphael, Iun Veng Leong, Angineh Aghakiant, Immalla Grace Chen, Scott Schumacher
  • Publication number: 20220066071
    Abstract: An optical system includes a bulk material including a fluorine (F)-containing optical material. The bulk material is exposed to an environment at a pressure ranging from atmospheric to vacuum when the bulk material is under extreme ultra-violet (EUV), vacuum ultra-violet (VUV), deep ultra-violet (DUV) and/or UV radiation. The environment includes at least one type of gas or vapor. The at least one type of gas or vapor includes polar molecules.
    Type: Application
    Filed: August 4, 2021
    Publication date: March 3, 2022
    Inventors: Evgeniia Butaeva, Gildardo Delgado, Grace Chen, John Savee, Matthew Derstine, Vera (Guorong) Zhuang, Gary V. Lopez Lopez
  • Publication number: 20220049345
    Abstract: An optical component includes an optical material which is a fluorine (F)-containing optical material doped with an F-containing species different from the F-containing optical material. A coating system for depositing the optical material onto a substrate or a bulk material of an optical component is an electron beam evaporation coating system, an ion assisted deposition coating system, or an ion beam sputtering coating system.
    Type: Application
    Filed: August 4, 2021
    Publication date: February 17, 2022
    Inventors: Gildardo Delgado, Vera (Guorong) Zhuang, John Savee, Evgeniia Butaeva, Gary V. Lopez Lopez, Grace Chen
  • Publication number: 20220044905
    Abstract: A material recovery system for an optical component includes a reservoir containing gas and configured to supply a gas flow containing the gas. The material recovery system also includes an ion beam generator disposed on the reservoir and configured to receive the gas flow and to ionize the gas in the gas flow to generate an ion beam. The ion beam is configured to be directed to the optical component to remove at least a portion of a F-containing optical material degraded by exposure to VUV radiation, DUV radiation, and/or photo-contamination.
    Type: Application
    Filed: August 4, 2021
    Publication date: February 10, 2022
    Inventors: Gildardo Delgado, Vera (Guorong) Zhuang, John Savee, Evgeniia Butaeva, Gary V. Lopez Lopez, Grace Chen
  • Patent number: 11208653
    Abstract: Methods and compositions for increasing RNAi efficiency through single nucleotide mismatches.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: December 28, 2021
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Grace Chen, David Bartel, Hazel Sive
  • Publication number: 20210176279
    Abstract: Predicting access impact of a plurality of rule changes on a corpus of information assets is provided. A set of affected rules in a new rule space for controlling access to the corpus of information assets is received. The set of affected rules is shredded to identify right-hand side terms contained in predication blocks of the set of affected rules. An enforcement knowledge graph is traversed to identify a set of hot information assets having same terms as the right-hand side terms of the set of affected rules. The set of hot information assets having the same terms as the right-hand side terms of the set of affected rules is added to a hash table of hot information assets.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 10, 2021
    Inventors: Roger C. Raphael, Iun Veng Leong, Angineh Aghakiant, Immalla Grace Chen, Scott Schumacher
  • Publication number: 20210130819
    Abstract: Methods and compositions for increasing RNAi efficiency through single nucleotide mismatches.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 6, 2021
    Inventors: Grace Chen, David Bartel, Hazel Sive