Abstract: This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types of particles in a portion of the sample using a first electrical differential counter to generate a first total; removing any particles of interest from the portion of the fluid sample; counting any particles remaining in the portion of the fluid sample using a second electrical differential counter after the particles of interest are removed to generate a second total; and calculating a number of particles of interest originally in the fluid sample by subtracting the second total from the first total, wherein the difference is the number of particles of interest in the sample. These methods and related devices can be used, for example, to produce a robust, inexpensive diagnostic kit for CD4+ T cell counting in whole blood samples.

Abstract: Method, systems, and apparatus for a method of processing a payment transaction using a mobile device of a merchant. In one aspect, determining the mobile device does not have a connection to an external network; receiving data indicating a payment transaction between a customer and the merchant; determining whether the payment transaction should be stored, where the determining is based on a risk heuristic model that considers one or more of the following: a number of already stored transactions, a value of the payment transaction, a total value, where the total value is a sum of the value of the payment transaction and values of one or more already stored transactions, and risk factors associated with the customer; and based at least on the determination, storing the payment transaction on the mobile device for future processing.

Abstract: Compositions and methods of modulating an innate immune response with circular RNAs are disclosed. In particular, the disclosure relates to methods for modifying an RNA by circularization and the use of circular RNAs generated with exogenous introns to stimulate an innate immune response or circular RNAs generated with endogenous introns to prevent immune recognition of foreign RNA.

Abstract: A system for network communication, preferably including: a plurality of nodes, a central routing server, a plurality of routers, a plurality of antennae, and/or one or more Internet sources. A method for configuring radio communication devices, preferably including: determining an installation region, determining candidate radio cluster locations, evaluating candidate radio cluster locations, and/or determining information associated with radio installation.

Abstract: A system for network communication, preferably including: a plurality of nodes, a central routing server, a plurality of routers, a plurality of antennae, and/or one or more Internet sources. A method for configuring radio communication devices, preferably including: determining an installation region, determining candidate radio cluster locations, evaluating candidate radio cluster locations, and/or determining information associated with radio installation.

Abstract: A method includes determining if a workflow step has an unsatisfied dependency; setting a state of the workflow step to a blocked state if the workflow step has an unsatisfied dependency; executing the workflow step if the workflow step does not have an unsatisfied dependency; setting the state of the workflow step to a cancelled state if, after executing the workflow step; the workflow step is cancelled; setting the state of the workflow step to a success state if, after executing the workflow step, the workflow step is executed successfully; setting the state of the workflow step to an error state if, after executing the workflow step, the workflow step is executed unsuccessfully; setting a state of a workflow to a success state if the workflow is executed successfully; and notifying other nodes of the state of the workflow step and the state of the workflow using a database replication.

Abstract: Methods and systems for determining a configuration for an optical element positioned in a collection aperture during wafer inspection are provided. One system includes a detector configured to detect light from a wafer that passes through an optical element, which includes a set of collection apertures, when the optical element has different configurations thereby generating different images for the different configurations. The system also includes a computer subsystem configured for constructing additional image(s) from two or more of the different images, and the two or more different images used to generate any one of the additional image(s) do not include only different images generated for single collection apertures in the set. The computer subsystem is further configured for selecting one of the different or additional configurations for the optical element based on the different images and the additional image(s).

Abstract: This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types of particles in a portion of the sample using a first electrical differential counter to generate a first total; removing any particles of interest from the portion of the fluid sample; counting any particles remaining in the portion of the fluid sample using a second electrical differential counter after the particles of interest are removed to generate a second total; and calculating a number of particles of interest originally in the fluid sample by subtracting the second total from the first total, wherein the difference is the number of particles of interest in the sample. These methods and related devices can be used, for example, to produce a robust, inexpensive diagnostic kit for CD4+ T cell counting in whole blood samples.

Abstract: This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types of particles in a portion of the sample using a first electrical differential counter to generate a first total; removing any particles of interest from the portion of the fluid sample; counting any particles remaining in the portion of the fluid sample using a second electrical differential counter after the particles of interest are removed to generate a second total; and calculating a number of particles of interest originally in the fluid sample by subtracting the second total from the first total, wherein the difference is the number of particles of interest in the sample. These methods and related devices can be used, for example, to produce a robust, inexpensive diagnostic kit for CD4+ T cell counting in whole blood samples.

Abstract: Methods and systems for determining a configuration for an optical element positioned in a collection aperture during wafer inspection are provided. One system includes a detector configured to detect light from a wafer that passes through an optical element, which includes a set of collection apertures, when the optical element has different configurations thereby generating different images for the different configurations. The system also includes a computer subsystem configured for constructing additional image(s) from two or more of the different images, and the two or more different images used to generate any one of the additional image(s) do not include only different images generated for single collection apertures in the set. The computer subsystem is further configured for selecting one of the different or additional configurations for the optical element based on the different images and the additional image(s).

Abstract: Methods and systems for determining a configuration for an optical element positioned in a collection aperture during wafer inspection are provided. One system includes a detector configured to detect light from a wafer that passes through an optical element, which includes a set of collection apertures, when the optical element has different configurations thereby generating different images for the different configurations. The system also includes a computer subsystem configured for constructing additional image(s) from two or more of the different images, and the two or more different images used to generate any one of the additional image(s) do not include only different images generated for single collection apertures in the set. The computer subsystem is further configured for selecting one of the different or additional configurations for the optical element based on the different images and the additional image(s).

Abstract: The present invention includes generating illumination, providing a spatial light modulator (SLM) configured to selectably illuminate one or more portions of a surface of a wafer using the generated illumination, receiving a sets of wafer pattern data indicative of one or more patterns of the wafer, translating the wafer along a direction, selectably controlling a pixel configuration of the SLM to control an illumination pattern on the surface of the wafer, a first pixel configuration illuminating a first set of regions of the wafer at an illumination level, an additional pixel configuration illuminating an additional set of regions at an additional illumination level, wherein a pixel pattern of the SLM based on the received sets of wafer pattern data is configured to move across a surface of the SLM synchronously with the pattern of the translated wafer, and detecting illumination from the surface of the wafer.

Abstract: A method includes determining if a workflow step has an unsatisfied dependency; setting a state of the workflow step to a blocked state if the workflow step has an unsatisfied dependency; executing the workflow step if the workflow step does not have an unsatisfied dependency; setting the state of the workflow step to a cancelled state if, after executing the workflow step; the workflow step is cancelled; setting the state of the workflow step to a success state if, after executing the workflow step, the workflow step is executed successfully; setting the state of the workflow step to an error state if, after executing the workflow step, the workflow step is executed unsuccessfully; setting a state of a workflow to a success state if the workflow is executed successfully; and notifying other nodes of the state of the workflow step and the state of the workflow using a database replication.

Abstract: The devices and systems described herein include one or more fluid paths, e.g., channels, and one or more selectively permeable obstacles arranged in the fluid path(s), each including a plurality of aligned nanostructures, e.g., nanotubes or nanorods, defining an outer surface of the obstacle and an internal network of voids. The obstacle(s) can further include binding moieties applied to the outer surface and/or to the surfaces of the individual nanostructures within the obstacle(s). The devices can be manufactured by forming the dense groupings of nanostructures to extend outwards and upwards from a substrate; forming a fluidic channel, bonding the fluidic channel to the substrate; and optionally applying binding moieties to the obstacles. The devices can be used to manipulate cells within fluid samples.

Abstract: Methods and systems for determining a configuration for an optical element positioned in a collection aperture during wafer inspection are provided. One system includes a detector configured to detect light from a wafer that passes through an optical element, which includes a set of collection apertures, when the optical element has different configurations thereby generating different images for the different configurations. The system also includes a computer subsystem configured for constructing additional image(s) from two or more of the different images, and the two or more different images used to generate any one of the additional image(s) do not include only different images generated for single collection apertures in the set. The computer subsystem is further configured for selecting one of the different or additional configurations for the optical element based on the different images and the additional image(s).

Abstract: Information regarding a redemption code may include at least one parameter associated with certain redeemable content. Requests may be received from a user. The request may concern access to redeemable content associated with a redemption code. The applicability of parameters is determined as is the redeemable content associated with the identified parameter. The user may then be granted access to the identified redeemable content. The determination of applicable parameters may include identifying an associated modification and applying the modification to the redemption code in order to identify the redeemable content.

Abstract: A key set is registered. The registering the key set includes registering a first shared data resource key. The first shared data resource key includes a first identifier associating a first process with a first shared data resource. The registering the key set further includes registering a second shared data resource key, and the second shared data resource key includes a second identifier associating a second process with a second shared data resource. A failure of a first process is detected, and in response to the detecting the failure of the first process, the first shared data resource key is de-registered. The second shared data resource key remains registered after the de-registering the first shared data resource key.